TY - JOUR A1 - Waldvogel, Janice A1 - Ritzmann, Ramona A1 - Freyler, Kathrin A1 - Helm, Michael A1 - Monti, Elena A1 - Albracht, Kirsten A1 - Stäudle, Benjamin A1 - Gollhofer, Albert A1 - Narici, Marco T1 - The Anticipation of Gravity in Human Ballistic Movement JF - Frontiers in Physiology N2 - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation. Y1 - 2021 U6 - https://doi.org/10.3389/fphys.2021.614060 SN - 1664-042X PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Lowis, Carsten A1 - Ferguson, Simon A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia T1 - Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron JF - Applied Radiation and Isotopes Y1 - 2021 U6 - https://doi.org/10.1016/j.apradiso.2021.109675 SN - 0969-8043 VL - 172 IS - Art. 109675 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wert, Stefan A1 - Iken, Heiko A1 - Schöning, Michael Josef A1 - Matysik, Frank-Michael T1 - Development of a temperature‐pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy JF - Electroanalysis N2 - Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating. Y1 - 2021 U6 - https://doi.org/10.1002/elan.202100089 SN - 1521-4109 IS - Early View PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Maurischat, Andreas T1 - Algebraic independence of the Carlitz period and its hyperderivatives KW - Drinfeld modules KW - t-modules KW - Transcendence KW - Hyperdifferentials Y1 - 2021 N1 - Zweitveröffentlichung. Verlagsveröffentlichung: https://doi.org/10.1016/j.jnt.2022.01.006 SP - 1 EP - 12 ER - TY - CHAP A1 - El Moussaoui, Noureddine A1 - Kassmi, Khalil A1 - Alexopoulos, Spiros A1 - Schwarzer, Klemens A1 - Chayeb, Hamid A1 - Bachiri, Najib T1 - Simulation studies on a new innovative design of a hybrid solar distiller MSDH alimented with a thermal and photovoltaic energy T2 - Materialstoday: Proceedings N2 - In this paper, we present the structure, the simulation the operation of a multi-stage, hybrid solar desalination system (MSDH), powered by thermal and photovoltaic (PV) (MSDH) energy. The MSDH system consists of a lower basin, eight horizontal stages, a field of four flat thermal collectors with a total area of 8.4 m2, 3 Kw PV panels and solar batteries. During the day the system is heated by thermal energy, and at night by heating resistors, powered by solar batteries. These batteries are charged by the photovoltaic panels during the day. More specifically, during the day and at night, we analyse the temperature of the stages and the production of distilled water according to the solar irradiation intensity and the electric heating power, supplied by the solar batteries. The simulations were carried out in the meteorological conditions of the winter month (February 2020), presenting intensities of irradiance and ambient temperature reaching 824 W/m2 and 23 °C respectively. The results obtained show that during the day the system is heated by the thermal collectors, the temperature of the stages and the quantity of water produced reach 80 °C and 30 Kg respectively. At night, from 6p.m. the system is heated by the electric energy stored in the batteries, the temperature of the stages and the quantity of water produced reach respectively 90 °C and 104 Kg for an electric heating power of 2 Kw. Moreover, when the electric power varies from 1 Kw to 3 Kw the quantity of water produced varies from 92 Kg to 134 Kg. The analysis of these results and their comparison with conventional solar thermal desalination systems shows a clear improvement both in the heating of the stages, by 10%, and in the quantity of water produced by a factor of 3. Y1 - 2021 U6 - https://doi.org/10.1016/j.matpr.2021.03.115 SN - 2214-7853 N1 - The Fourth edition of the International Conference on Materials & Environmental Science (ICMES 2020), virtual conference, November 18-28, 2020, Morocco VL - 45 IS - 8 SP - 7653 EP - 7660 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Molinnus, Denise A1 - Drinic, Aleksander A1 - Iken, Heiko A1 - Kröger, Nadja A1 - Zinser, Max A1 - Smeets, Ralf A1 - Köpf, Marius A1 - Kopp, Alexander A1 - Schöning, Michael Josef T1 - Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk JF - Biosensors and Bioelectronics Y1 - 2021 U6 - https://doi.org/10.1016/j.bios.2021.113204 SN - 0956-5663 VL - 183 IS - Art. 113204 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Bayer, Robin T1 - Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:38-362212 N1 - Dissertation, Universität zu Köln, 2021 PB - Universität zu Köln CY - Köln ER - TY - BOOK A1 - Laack, Walter van T1 - Größer als das ganze Universum Y1 - 2021 SN - 978-3-936624-38-0 PB - van Laack GmbH CY - Aachen ER - TY - JOUR A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing JF - Current Opinion in Electrochemistry Y1 - 2021 U6 - https://doi.org/10.1016/j.coelec.2021.100727 SN - 2451-9103 IS - In Press, Journal Pre-proof PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hennes, Philipp A1 - Laumann, Jörg T1 - Ansatz der Drehbehinderung aus Koppelpfetten mit dünnwandigen kaltgeformten Z-Profilen JF - Stahlbau Y1 - 2021 U6 - https://doi.org/10.1002/stab.202000104 SN - 1437-1049 VL - 90 IS - 3 SP - 158 EP - 168 PB - Ernst & Sohn CY - Berlin ER -