TY - JOUR A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Tastambek, Kuanysh T. A1 - Marat, Adel K. A1 - Turaliyeva, Moldir A. A1 - Kaiyrmanova, Gulzhan K. T1 - Biotechnology of Microorganisms from Coal Environments: From Environmental Remediation to Energy Production JF - Biology N2 - It was generally believed that coal sources are not favorable as live-in habitats for microorganisms due to their recalcitrant chemical nature and negligible decomposition. However, accumulating evidence has revealed the presence of diverse microbial groups in coal environments and their significant metabolic role in coal biogeochemical dynamics and ecosystem functioning. The high oxygen content, organic fractions, and lignin-like structures of lower-rank coals may provide effective means for microbial attack, still representing a greatly unexplored frontier in microbiology. Coal degradation/conversion technology by native bacterial and fungal species has great potential in agricultural development, chemical industry production, and environmental rehabilitation. Furthermore, native microalgal species can offer a sustainable energy source and an excellent bioremediation strategy applicable to coal spill/seam waters. Additionally, the measures of the fate of the microbial community would serve as an indicator of restoration progress on post-coal-mining sites. This review puts forward a comprehensive vision of coal biodegradation and bioprocessing by microorganisms native to coal environments for determining their biotechnological potential and possible applications. Y1 - 2022 U6 - http://dx.doi.org/10.3390/biology11091306 SN - 2079-7737 N1 - This article belongs to the Special Issue "Microbial Ecology and Evolution in Extreme Environments" VL - 11 IS - 9 PB - MDPI CY - Basel ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Sherelkhan, Dinara K. A1 - Razzaque, Mohammed S. T1 - Vitamin D and Phosphate Interactions in Health and Disease T2 - Phosphate Metabolism N2 - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease. KW - Vitamin D KW - PTH KW - Phosphate KW - FGF23 KW - Klotho Y1 - 2022 SN - 978-3-030-91621-3 U6 - http://dx.doi.org/10.1007/978-3-030-91623-7_5 SP - 37 EP - 46 PB - Springer CY - Cham ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Razzaque, Mohammed S. T1 - Role of vitamins in maintaining structure and function of intestinal microbiome T2 - Comprehensive Gut Microbiota N2 - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota. KW - Vitamin A KW - Vitamin B KW - Thiamine KW - Riboflavin KW - Niacin Y1 - 2022 SN - 978-0-12-822036-8 U6 - http://dx.doi.org/10.1016/B978-0-12-819265-8.00043-7 SP - 320 EP - 334 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Abbas, Karim A1 - Balc, Nicolae A1 - Bremen, Sebastian A1 - Skupin, Marco T1 - Crystallization and aging behavior of polyetheretherketone PEEK within rapid tooling and rubber molding JF - Journal of Manufacturing and Materials Processing N2 - In times of short product life cycles, additive manufacturing and rapid tooling are important methods to make tool development and manufacturing more efficient. High-performance polymers are the key to mold production for prototypes and small series. However, the high temperatures during vulcanization injection molding cause thermal aging and can impair service life. The extent to which the thermal stress over the entire process chain stresses the material and whether it leads to irreversible material aging is evaluated. To this end, a mold made of PEEK is fabricated using fused filament fabrication and examined for its potential application. The mold is heated to 200 ◦C, filled with rubber, and cured. A differential scanning calorimetry analysis of each process step illustrates the crystallization behavior and first indicates the material resistance. It shows distinct cold crystallization regions at a build chamber temperature of 90 ◦C. At an ambient temperature above Tg, crystallization of 30% is achieved, and cold crystallization no longer occurs. Additional tensile tests show a decrease in tensile strength after ten days of thermal aging. The steady decrease in recrystallization temperature indicates degradation of the additives. However, the tensile tests reveal steady embrittlement of the material due to increasing crosslinking. KW - additive manufacturing KW - fused filament fabrication KW - crystallization KW - polyetheretherketone KW - rapid tooling Y1 - 2022 U6 - http://dx.doi.org/10.3390/jmmp6050093 SN - 2504-4494 N1 - The article belongs to the Special Issue Advances in Injection Molding: Process, Materials and Applications VL - 6 IS - 5 SP - 1 EP - 12 PB - MDPI CY - Basel ER - TY - JOUR T1 - Dimensionen 1-2022: Magazin der FH Aachen University of Applied Sciences - Auf dem Weg zur Nachhaltigkeit N2 - Inhaltsverzeichnis: 06| "WIR" werden nachhaltig 10| Der Kraft-Stoff aus dem Bioreaktor 14| Energieverbrauch des Campus Jülich optimieren 16| „Eine große Hilfestellung für Flutopfer“ 20| Von der ersten Skizze zu den Blumen in der Vase 22|Wie schläft es sich im All, Herr Maurer? 24| Expedition Arktis 28| Eine Frage, zwei Antworten 30| Der schönste Arbeitsplatz der Welt 32| Im Einklang 36| Ein Vorgeschmack auf die echte Arbeitswelt 38| Den Rätseln des Universums auf der Spur 40| Auf Umwegen in die Spitzenforschung 42| Klappe FH Aachen, die erste … Kamera läuft! 44| Auszeit 46| „Fotografie öffnet Türen zu Parallelwelten“ 50| Es gibt viel zu tun 52| Durch-Blick 54| Weichen stellen für einen ganz besonderen Job 58| Souta, Iver und der Wind 60| Die FH Aachen ist systemakkreditiert 61| Der Vulkan 62| Kopfnuss, Impressum T3 - Dimensionen - Magazin der FH Aachen University of Applied Sciences - 2022, 1 Y1 - 2022 CY - Aachen ER - TY - JOUR T1 - Dimensionen 2-2022: Magazin der FH Aachen University of Applied Sciences - Werkstatt Zukunft N2 - Werkstatt Zukunft - Die FH Aachen versteht sich als interdisziplinäre Ideenschmiede 04| Aufbruch ins Ungewisse 08| Mit Altpapierresten aus der Energiekrise 14| Mehr Power für die Energiewende 20| Pfadfinder im Datendschungel 23| Ein historischer Schritt 24| Gemeinsam vorwärts 30| Für eine gerechte Hochschule. Für alle. 32| Der grüne Reiter 34| Vom Flugsimulator bis zum Roboter 36| Unsere Azubis sind top! 38| WIR sind ein Sportteam! 40| Effizient und sicher: Der Bergbau der Zukunft 46| Mit Sonnenlicht zu sauberem Trinkwasser 48| Neue Brandmeldeanlage für den Dom zu Aachen 50| Auszeichnung für außergewöhnliches Engagement 52| Neue Ideen für Schloss Lichtenburg 55| Kopfnuss 56| One-Man-Show 60| Kämpferin für das Schöne 61| Ein charmanter Diplomat 62| Teamplay für die Zukunft 63| Impressum T3 - Dimensionen - Magazin der FH Aachen University of Applied Sciences - 2022, 2 Y1 - 2022 CY - Aachen ER -