TY  - JOUR
A1  - Turek, M.
A1  - Keusgen, M.
A1  - Poghossian, Arshak
A1  - Mulchandani, A.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - Enzyme-modified electrolyte-insulator-semiconductor sensors
JF  - Journal of Contemporary Physics. 43 (2008), H. 2
Y1  - 2008
SN  - 1934-9378
N1  - Armenian Academy of Sciences
SP  - 82
EP  - 85
ER  - 
TY  - JOUR
A1  - Katz, Evgeny
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics
JF  - Analytical and Bioanalytical Chemistry
N2  - The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a “filter” system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.
Y1  - 2017
U6  - http://dx.doi.org/10.1007/s00216-016-0079-7
SN  - 1618-2650
VL  - 409
SP  - 81
EP  - 94
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Katz, Evgeny
A1  - Schöning, Michael Josef
T1  - Enzyme logic AND-Reset and OR-Reset gates based on a field-effect electronic transducer modified with multi-enzyme membrane
JF  - Chemical Communications
N2  - Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.
Y1  - 2015
U6  - http://dx.doi.org/10.1039/C5CC01362C
VL  - 51
SP  - 6564
EP  - 6567
PB  - Royal Society of Chemistry (RSC)
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Malkoc, Ü.
A1  - Dicker, C. I.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Enzyme immobilisation on planar and porous silicon substrates for biosensor applications
JF  - Journal of Molecular Catalysis B: Enzymatic. 7 (1999), H. 1-4
Y1  - 1999
SN  - 1381-1177
SP  - 77
EP  - 83
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Bäcker, Matthias
A1  - Krischer, M.
A1  - Wenzel, L.
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor
JF  - Procedia Engineering
N2  - A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.
KW  - Field-effect sensor
KW  - enzymatic (bio)degradation
KW  - poly(d, l-lactic acid)
KW  - in-situ monitoring
KW  - impedance spectroscopy
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.proeng.2014.11.689
SN  - 1877-7058
N1  - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014>
VL  - 87
SP  - 1314
EP  - 1317
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Keusgen, M.
A1  - Jünger, M.
A1  - Knobbe, D.-T.
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Entwicklung eines potentiometrischen Cyanid-Biosensors auf der Basis von EIS-Strukturen
JF  - Sensoren für zukünftige Hochtechnologien und Neuentwicklungen für die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. Jörg Peter Baselt; Gerald Gerlach (Hg.)
Y1  - 2003
SN  - 3-935712-92-8
SP  - 235
EP  - 238
PB  - w.e.b.-Univ.-Verl.
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Schnitzler, Thomas
A1  - Biselli, Manfred
A1  - Zang, Werner
A1  - Wagner, P.
T1  - Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermentationen
JF  - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)
Y1  - 2010
SN  - 978-3-8007-3260-9
N1  - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik
SP  - 688
EP  - 698
PB  - VDE Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Schnitzler, Thomas
A1  - Zang, Werner
A1  - Wagner, P.
T1  - Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermenationen
JF  - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)
Y1  - 2010
SN  - 978-3-8007-3260-9
N1  - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik
SP  - 688
EP  - 691
PB  - VDE Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Henkel, H.
A1  - Schneider, A.
A1  - Schäfer, D.
A1  - Friedrich, P.
A1  - Berger, J.
A1  - Schöning, Michael Josef
T1  - Entwicklung eines Handheld-Sensorsystems für die „On-line“-Messung der H2O2-Konzentration in aseptischen Entkeimungsprozessen
JF  - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]
Y1  - 2009
SN  - 978-3-941298-44-6
N1  - Dresdner Sensor-Symposium ; (9, 2009, Dresden)
SP  - 285
EP  - 288
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Kowollik, Silvia
A1  - Schnitzler, Thomas
A1  - Wang, J.
A1  - Poghossian, Arshak
A1  - Zang, Werner
A1  - Biselli, Manfred
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Entwicklung eines festkörperbasierten Sensorsystems für die Bioprozessautomatisierung
JF  - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]
Y1  - 2009
SN  - 978-3-941298-44-6
N1  - Dresdner Sensor-Symposium ; (9, 2009, Dresden)
SP  - 197
EP  - 200
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Näther, Niko
A1  - Berger, Jörg
A1  - Emmerich, Rüdiger
A1  - Friedrich, Peter
A1  - Henkel, Hartmut
A1  - Schneider, Andreas
A1  - Schöning, Michael Josef
T1  - Entwicklung einer kalorimetrischen H2O2-Gassensoranordnung für die Prozessgaskontrolle
JF  - 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)
Y1  - 2007
SN  - 978-3-940046-45-1
N1  - Dresdner Beiträge zur Sensorik ; 29
SP  - 261
EP  - 264
PB  - TUDpress, Verl. der Wissenschaften
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Miyamoto, K.
A1  - Seki, K.
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination
JF  - Procedia Engineering
N2  - The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm.
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.proeng.2014.11.563
SN  - 1877-7058
N1  - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014>
VL  - 87
SP  - 612
EP  - 615
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Doll, Theodor
A1  - Wagner, Torsten
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Engineering of functional interfaces / Theodor Doll ; Torsten Wagner ; Patrick Wagner ; Michael J. Schöning (eds.)
JF  - Physica status solidi (a)
Y1  - 2016
U6  - http://dx.doi.org/10.1002/pssa.201670641
SN  - 1862-6319
VL  - 213
IS  - 6
SP  - 1393
EP  - 1394
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Wagner, Patrick
A1  - Doll, Theodor
A1  - Schöning, Michael Josef
T1  - Engineering of functional interfaces / Patrick Wagner ; Theodor Doll ; Michael J. Schöning (eds.)
JF  - Physica status solidi (A) : Applications and materials science
Y1  - 2014
U6  - http://dx.doi.org/10.1002/pssa.201470241
SN  - 1521-396X (E-Book); 1862-6319 (E-Book); 0031-8965 (Print); 1862-6300 (Print)
VL  - 211
IS  - 6
SP  - 1339
EP  - 1339
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Bronder, Thomas
A1  - Poghossian, Arshak
A1  - Scheja, S.
A1  - Wu, Chunsheng
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Electrostatic Detection of Unlabelled Single- and Double-stranded DNA Using Capacitive Field-effect Devices Functionalized with a Positively Charged Polyelectrolyte Layer
JF  - Procedia Engineering
N2  - Capacitive field-effect electrolyte-insulator-semiconductor sensors consisting of an Al-p-Si-SiO2 structure have been used for the electrical detection of unlabelled single- and double-stranded DNA (dsDNA) molecules by their intrinsic charge. A simple functionalization protocol based on the layer-by-layer (LbL) technique was used to prepare a weak polyelectrolyte/probe-DNA bilayer, followed by the hybridization with complementary target DNA molecules. Due to the flat orientation of the LbL-adsorbed DNA molecules, a high sensor signal has been achieved. In addition, direct label-free detection of in-solution hybridized dsDNA molecules has been studied.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.proeng.2015.08.710
SN  - 1877-7058
N1  - Eurosensors 2015
VL  - 120
SP  - 544
EP  - 547
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Murib, M. S.
A1  - Grinsven, B. van
A1  - Grieten, L.
A1  - Janssens, S. D.
A1  - Vermeeren, V.
A1  - Eersels, K.
A1  - Broeders, J.
A1  - Ameloot, M.
A1  - Michiels, L.
A1  - Ceuninck, W. De
A1  - Haenen, K.
A1  - Schöning, Michael Josef
A1  - Wagner, Patrick
T1  - Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates
JF  - Physica Status Solidi (A). Vol. 210 (2013), iss. 5
Y1  - 2013
SN  - 0031-8965
SP  - 911
EP  - 917
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Moreno i Codinachs, Lia
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
A1  - Baldi, Antoni
A1  - Ipatov, Andrey
A1  - Bratov, Andrey
A1  - Jimenez-Jorquera, Cecilia
T1  - Electronic integrated multisensor tongue applied to grape juice and wine analysis
JF  - Analyst. 133 (2008)
Y1  - 2008
SN  - 1364-5528
SP  - 1440
EP  - 1448
ER  - 
TY  - JOUR
A1  - Honarvarfard, Elham
A1  - Gamella, Maria
A1  - Channaveerappa, Devika
A1  - Darie, Costel C.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - Electrochemically Stimulated Insulin Release from a Modified Graphene–functionalized Carbon Fiber Electrode
JF  - Electroanalysis
N2  - A graphene-functionalized carbon fiber electrode was modified with adsorbed polyethylenimine to introduce amino functionalities and then with trigonelline and 4-carboxyphenylboronic acid covalently bound to the amino groups. The trigonelline species containing quarterized pyridine groups produced positive charge on the electrode surface regardless of the pH value, while the phenylboronic acid species were neutral below pH 8 and negatively charged above pH 9 (note that their pKa=8.4). The total charge on the monolayer-modified electrode was positive at the neutral pH and negative at pH > 9. Note that 4-carboxyphenylboronic acid was attached to the electrode surface in molar excess to trigonelline, thus allowing the negative charge to dominate on the electrode surface at basic pH. Negatively charged fluorescent dye-labeled insulin (insulin-FITC) was loaded on the modified electrode surface at pH 7.0 due to its electrostatic attraction to the positively charged interface. The local pH in close vicinity to the electrode surface was increased to ca. 9–10 due to consumption of H+ ions upon electrochemical reduction of oxygen proceeding at the potential of −1.0 V (vs. Ag/AgCl) applied on the modified electrode. The process resulted in recharging of the electrode surface to the negative value due to the formation of the negative charge on the phenylboronic acid groups, thus resulting in the electrostatic repulsion of insulin-FITC and stimulating its release from the electrode surface. The insulin release was characterized by fluorescence spectroscopy (using the FITC-labeled insulin), by electrochemical measurements on an iridium oxide, IrOx, electrode and by mass spectrometry. The graphene-functionalized carbon fiber electrode demonstrated significant advantages in the signal-stimulated insulin release comparing with the carbon fiber electrode without the graphene species.
Y1  - 2017
U6  - http://dx.doi.org/10.1002/elan.201700095
SN  - 1521-4109
VL  - 29
IS  - 6
SP  - 1543
EP  - 1553
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Delle, L.
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Zang, Werner
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Electrochemical sensor array for bioprocess monitoring
JF  - Electrochimica Acta (2011)
Y1  - 2011
VL  - 56
IS  - 26
SP  - 9673
EP  - 9678
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Glück, O.
A1  - Thust, M.
T1  - Electrochemical methods for the determination of chemical variables in aqueous media
JF  - The measurement, instrumentation, and sensors handbook / ed.-in-chief John G. Webster. In cooperation with IEEE Press
Y1  - 1999
SN  - 0-8493-8347-1
SP  - 1
EP  - 49
PB  - CRC Press
CY  - Boca Raton [u.a.]
ER  -