TY  - JOUR
A1  - Tippkötter, Nils
A1  - Al-Kaidy, Huschyar
A1  - Wollny, Steffen
A1  - Ulber, Roland
T1  - Functionalized magnetizable particles for downstream processing in single-use systems
JF  - Chemie Ingenieur Technik
N2  - Biotechnological downstream processing is usually an elaborate procedure, requiring a multitude of unit operations to isolate the target component. Besides the disadvantageous space-time yield, the risks of cross-contaminations and product loss grow fast with the complexity of the isolation procedure. A significant reduction of unit operations can be achieved by application of magnetic particles, especially if these are functionalized with affinity ligands. As magnetic susceptible materials are highly uncommon in biotechnological processes, target binding and selective separation of such particles from fermentation or reactions broths can be done in a single step. Since the magnetizable particles can be produced from iron salts and low priced polymers, a single-use implementation of these systems is highly conceivable. In this article, the principles of magnetizable particles, their synthesis and functionalization are explained. Furthermore, applications in the area of reaction engineering, microfluidics and downstream processing are discussed focusing on established single-use technologies and development potential.
Y1  - 2013
U6  - https://doi.org/10.1002/cite.201200130
VL  - 85
IS  - 1-2: Special Issue: Single-Use Technology
SP  - 76
EP  - 86
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Anding, Ralf
A1  - Tabaza, Ruth
A1  - Staat, Manfred
A1  - Trenz, Eva
A1  - Lohmann, Philipp
A1  - Klinge, Uwe
A1  - Kirschner-Hermanns, Ruth
T1  - Introducing a method of in vitro testing of different anchoring systems used for female incontinence and prolapse surgery
JF  - BioMed research international
Y1  - 2013
SN  - 1110-7251 (E-Journal); 2314-6141 (E-Journal); 1110-7243 (Print); 2314-6133 (Print)
VL  - Vol. 2013
SP  - Article ID 401417
ER  - 
TY  - CHAP
A1  - Duprat, J.
A1  - Dachwald, Bernd
A1  - Hilchenbach, M.
A1  - Engrand, Cecile
A1  - Espe, C.
A1  - Feldmann, M.
A1  - Francke, Gero
A1  - Görög, Mark
A1  - Lüsing, N.
A1  - Langenhorst, Falko
T1  - The MARVIN project: a micrometeorite harvester in Antarctic snow
T2  - 44th Lunar and Planetary Science Conference
N2  - MARVIN is an automated drilling and melting probe dedicated to collect pristine interplanetary dust particles (micrometeorites) from central Antarctica snow.
Y1  - 2013
N1  - 44th Lunar and Planetary Science Conference, March 18-22, 2013, The Woodlands, Texas
ER  - 
TY  - JOUR
A1  - Jung, Alexander
A1  - Staat, Manfred
A1  - Müller, Wolfram
T1  - Flight style optimization in ski jumping on normal, large, and ski flying hills
JF  - Journal of biomechanics
Y1  - 2013
SN  - 1873-2380 (E-Journal); 0021-9290 (Print)
N1  - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716-722] Journal of Biomechanics, 2018;71:313.
VL  - Vol. 47
IS  - Iss. 3
SP  - 716
EP  - 722
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Wu, Chunsheng
A1  - Poghossian, Arshak
A1  - Werner, Frederik
A1  - Bronder, Thomas
A1  - Bäcker, Matthias
A1  - Wang, Ping
A1  - Schöning, Michael Josef
T1  - An application of a scanning light-addressable potentiometric sensor for label-free DNA detection
T2  - 11. Dresdner Sensor-Symposium : 9.-11.12.2013
Y1  - 2013
SN  - 978-3-9813484-5-3
SP  - 164
EP  - 168
ER  - 
TY  - JOUR
A1  - Rens, Gavin
A1  - Ferrein, Alexander
T1  - Belief-node condensation for online POMDP algorithms
N2  - Slightly extended version of the paper accepted at the Robotics and Artificial Intelligence Workshop, a special track of IEEE AFRICON-2013, held in Mauritius, 9-12 September 2013
Y1  - 2013
SP  - 1
EP  - 7
PB  - IEEE
CY  - New York
ER  - 
TY  - CHAP
A1  - Ferrein, Alexander
A1  - Niemüller, Tim
A1  - Schiffer, Stefan
A1  - Lakemeyer, Gerhard
ED  - Boots, Byron
T1  - Lessons learnt from developing the embodied AI platform CAESAR for domestic service robotics
T2  - Designing intelligent robots : reintegrating AI II ; papers from the AAAI spring symposium ; [held March 25 - 27, 2013 in Palo Alto, California, USA, on the campus of Stanford University]. (Technical Report / Association for the Advancement of Artificial Intelligence ; 2013,4)
Y1  - 2013
SN  - 9781577356011
SP  - 21
EP  - 26
ER  - 
TY  - CHAP
A1  - Leingartner, Max
A1  - Maurer, Johannes
A1  - Steinbauer, Gerald
A1  - Ferrein, Alexander
T1  - Evaluation of sensors and mapping approaches for disasters in tunnels
T2  - IEEE International Symposium on Safety, Security, and Rescue Robotics : SSRR : 21-26 Oct. 2013, Linkoping, Sweden
Y1  - 2013
SN  - 978-1-4799-0879-0
SP  - 1
EP  - 7
ER  - 
TY  - CHAP
A1  - Niemüller, Tim
A1  - Ewert, Daniel
A1  - Reuter, Sebastian
A1  - Ferrein, Alexander
A1  - Jeschke, Sabina
A1  - Lakemeyer, Gerhard
T1  - The Carologistics RoboCup Logistics Team 2013
T2  - RoboCup 2013 : Eindhoven
Y1  - 2013
SP  - 1
EP  - 8
ER  - 
TY  - CHAP
A1  - Heuermann, Holger
A1  - Sadeghfam, Arash
A1  - Finger, Torsten
T1  - Alternative ignition system based on microwave plasma
T2  - Advanced ignition systems for gasoline engines : [Vorträge der 1st International Conference Advanced Ignition Systems for Gasoline Engines - 1. Internationale Tagung Zündsysteme für Ottomotoren, 12.-13. November 2012, Berlin]
Y1  - 2013
SN  - 9783816931904
SP  - 95
EP  - 103
PB  - Expert-Verl.
CY  - Renningen
ER  - 
TY  - CHAP
A1  - Achenbach, Timm
A1  - Bosch, Timo
A1  - Breitbach, Gerd
A1  - Göttsche, Joachim
A1  - Sauerborn, Markus
T1  - Theoretical and experimental investigations regarding open volumetric receivers of CRS
T2  - Energy procedia : proceedings of the SolarPACES 2013 International Conference
Y1  - 2013
SN  - 1876-6102
VL  - Vol. 49
SP  - 1259
EP  - 1268
ER  - 
TY  - JOUR
A1  - Huck, Christina
A1  - Schiffels, Johannes
A1  - Herrera, Cony N.
A1  - Schelden, Maximilian
A1  - Selmer, Thorsten
A1  - Poghossian, Arshak
A1  - Baumann, Marcus
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor
JF  - Physica Status Solidi (A)
N2  - Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the “welfare” of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis–Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.
Y1  - 2013
U6  - https://doi.org/10.1002/pssa.201200900
SN  - 0031-8965
VL  - 210
IS  - 5
SP  - 926
EP  - 931
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties
JF  - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.)
Y1  - 2013
SN  - 978-94-007-5424-9
SP  - 89
EP  - 102
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Thiel, Alexander
A1  - Tippkötter, Nils
A1  - Suck, Kirstin
A1  - Sohling, Ulrich
A1  - Ruf, Friedrich
A1  - Ulber, Roland
T1  - New zeolite adsorbents for downstream processing of polyphenols from renewable resources
JF  - Engineering in Life Sciences
N2  - Commercial materials with polyvinylpolypyrrolidone and polymeric amberlites (XAD7HP, XAD16) are commonly used for the adsorptive downstream processing of polyphenols from renewable resources. In this study, beta-zeolite-based adsorbent systems were examined, and their properties were compared to organic resins. Batch adsorption experiments were conducted with synthetic solutions of major polyphenols. Adsorption isotherms and desorption characteristics of individual adsorbent were determined based on these results. Maximum adsorption capacities were calculated using the Langmuir model. For example, the zeolites had capacities up to 203.2 mg/g for ferulic acid. To extend these results to a complex system, additional experiments were performed on rapeseed meal and wheat seed extracts as representative renewable resources. HPLC analysis showed that with 7.5% w/v, which is regarded as the optimum amount of zeolites, zeolites A and B could bind 100% of the major polyphenols as well as release polyphenols at high yields. Additionally, regeneration experiments were performed with isopropyl alcohol at 99°C to evaluate how zeolites regenerate under mild conditions. The results showed only a negligible loss of adsorption capacity and no loss of desorption capacity. In summary, it was concluded that beta-zeolites were promising adsorbents for developing new processes to isolate polyphenols from renewable resources.
Y1  - 2013
U6  - https://doi.org/10.1002/elsc.201200188
VL  - 13
IS  - 3
SP  - 239
EP  - 246
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Limit and shakedown analysis under uncertainty
JF  - International journal of computational methods : IJCM
Y1  - 2013
SN  - 0219-8762
SP  - Publ. online
PB  - World Scientific Publishing
CY  - Singapore
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Menzel, S.
A1  - Bäcker, Matthias
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements
JF  - Electrochimica Acta
Y1  - 2013
SN  - 1873-3859 (E-Journal); 0013-4686 (Print)
VL  - Vol. 113
SP  - 779
EP  - 784
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Micili, Serap C.
A1  - Valter, Markus
A1  - Oflaz, Hakan
A1  - Ozogul, Candan
A1  - Linder, Peter
A1  - Föckler, Nicole
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Temiz Artmann, Aysegül
T1  - Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes
JF  - Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine
Y1  - 2013
SN  - 0046-2039 (Print) ; 2041-3033 (E-Journal)
VL  - Vol. 227
IS  - No. 4
SP  - 393
EP  - 401
PB  - Sage
CY  - London
ER  - 
TY  - CHAP
A1  - Becker, Jörg
A1  - Eggert, Mathias
A1  - Fleischer, Stefan
A1  - Knackstedt, Ralf
T1  - How to Teach Regulatory Compliant Data Warehouse Engineering?
T2  - Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013.
Y1  - 2013
N1  - AMCIS 2013 Proceedings
ER  - 
TY  - CHAP
A1  - Gogolin, C.
A1  - Carvalho, R.
A1  - Bung, Daniel Bernhard
A1  - Matos, J.
T1  - Experimental and numerical investigation of steady and unsteady flows in roughened channels with cross beams
T2  - 35th IAHR world congress : 8.-13.9.2013, Chengdu, China
Y1  - 2013
SP  - Artikelkennnummer: A10837C
PB  - Tsinghua Univ. Press
CY  - Beijing
ER  - 
TY  - CHAP
A1  - Oertel, Mario
A1  - Bung, Daniel Bernhard
T1  - Comparison of 2D dam-break waves with VOF and SPH method
T2  - Proceedings of the 35th IAHR world congress : 8.-13.9.2013, Chengdu, China
Y1  - 2013
SP  - Artikelkennnummer: A11113
PB  - Tsinghua Univ. Press
CY  - Beijing
ER  -