TY - JOUR A1 - Lagemaat, Miriam W. A1 - Vos, Eline K. A1 - Maas, Marnix C. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Uden, Mark J. van A1 - Kobus, Thiele A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - Phosphorus magnetic resonance spectroscopic imaging at 7 T in patients with prostate cancer JF - Investigative Radiology N2 - Objectives The aim of this study was to identify characteristics of phosphorus (³¹P) spectra of the human prostate and to investigate changes of individual phospholipid metabolites in prostate cancer through in vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) at 7 T. Materials and Methods In this institutional review board–approved study, 15 patients with biopsy-proven prostate cancer underwent T₂-weighted magnetic resonance imaging and 3-dimensional ³¹P MRSI at 7 T. Voxels were selected at the tumor location, in normal-appearing peripheral zone tissue, normal-appearing transition zone tissue, and in the base of the prostate close to the seminal vesicles. Phosphorus metabolite ratios were determined and compared between tissue types. Results Signals of phosphoethanolamine (PE) and phosphocholine (PC) were present and well resolved in most ³¹P spectra in the prostate. Glycerophosphocholine signals were observable in 43% of the voxels in malignant tissue, but in only 10% of the voxels in normal-appearing tissue away from the seminal vesicles. In many spectra, independent of tissue type, 2 peaks resonated in the chemical shift range of inorganic phosphate, possibly representing 2 separate pH compartments. The PC/PE ratio in the seminal vesicles was highly elevated compared with the prostate in 5 patients. A considerable overlap of ³¹P metabolite ratios was found between prostate cancer and normal-appearing prostate tissue, preventing direct discrimination of these tissues. The only 2 patients with high Gleason scores tumors (≥4+5) presented with high PC and glycerophosphocholine levels in their cancer lesions. Conclusions Phosphorus MRSI at 7 T shows distinct features of phospholipid metabolites in the prostate gland and its surrounding structures. In this exploratory study, no differences in ³¹P metabolite ratios were observed between prostate cancer and normal-appearing prostate tissue possibly because of the partial volume effects of small tumor foci in large MRSI voxels. Y1 - 2014 U6 - http://dx.doi.org/10.1097/RLI.0000000000000012 SN - 1536-0210 VL - 49 IS - 5 SP - 363 EP - 372 PB - Lippincott Williams & Wilkins CY - Philadelphia, Pa. ER - TY - CHAP A1 - Harzheim, Thomas A1 - Heuermann, Holger T1 - Phase Repeatable Synthesizers as a New Harmonic Phase Standard for Nonlinear Network Analysis T2 - IEEE Transactions on Microwave Theory and Techniques Y1 - 2018 U6 - http://dx.doi.org/10.1109/TMTT.2018.2817513 SP - 1 EP - 8 PB - IEEE ER - TY - CHAP A1 - Luczak, Holger A1 - Wolf, Martin A1 - Schlick, Christopher A1 - Springer, J. A1 - Foltz, Christian ED - Nagl, Walter T1 - Personenorientierte Arbeitsprozesse und Kommunikationsforrnen T2 - Integration von Entwicklungssystemen in Ingenieuranwendungen : substantielle Verbesserung der Entwicklungsprozesse Y1 - 1999 SN - 3-540-63920-9 SP - 403 EP - 422 PB - Springer CY - Berlin ER - TY - JOUR A1 - Ritz, Thomas T1 - Personalized Information Services: Production and Distribution of these Services employing Mass-Customization Y1 - 2002 N1 - International Congress on Mass Media and Communications in the e-society of the 21st Century, Moskau, 17.-19.10.2002 ER - TY - JOUR A1 - Ritz, Thomas T1 - Personalized information services : an electronic information commodity and its production JF - International Journal of E-Business Strategy Management Y1 - 2000 SN - 1467-0305 VL - 2 IS - 2 ER - TY - CHAP A1 - Ritz, Thomas T1 - Personalized information services : an electronic information commodity and its production T2 - Electronic publishing '01 : 2001 in the digital publishing odyssey ; proceedings of an ICCC/IFIP conference held at the University of Kent at Canterbury, Kent, United Kingdom, 5 - 7 July, 2001 ; [proceedings of the Fifth Conference on Electronic Publishing] Y1 - 2001 SN - 1-58603-191-0 SP - 48 EP - 58 PB - IOS Press [u.a.] CY - Amsterdam ER - TY - JOUR A1 - Ritz, Thomas A1 - Hoof, Antonius J. M. T1 - Personalisierung von Content basierten Services - Produktion von personalisierten Informationsdienstleistungen JF - Content Management : digitale Inhalte als Bausteine einer vernetzten Welt ; 18. Juni 2002, Stuttgart / Innovationsforum. Veranst. Verein zur Förderung Produktionstechnischer Forschung e.V., Stuttgart. [Fraunhofer-Institut Arbeitswirtschaft und Organisatio Y1 - 2002 SN - 3-8167-6155-0 SP - 91 EP - 106 PB - Fraunhofer-IRB-Verl. CY - Stuttgart ER - TY - JOUR A1 - Schuba, Marko A1 - Hermanns, Oliver T1 - Performance Investigations of the IP Multicast Architecture / Hermanns, Oliver ; Schuba, Marko JF - Performance of the IP Multicast Achitecture . Proceedings JENC 6. Proceedings of the 6th Joint European Networking Conference, Tel Aviv Y1 - 1995 N1 - Reprinted in Computer Networks and ISDN Systems 28 pp 429-439, 1996 SP - 121-1 EP - 121-8 ER - TY - JOUR A1 - Schuba, Marko A1 - Haverkort, Boudewijn R. A1 - Schneider, Gaby T1 - Performance evaluation of multicast communication in packet-switched networks / Schuba, Marko ; Haverkort, Boudewijn R. ; Schneider, Gaby JF - Performance Evaluation. 39 (2000), H. 1-4 Y1 - 2000 SN - 0166-5316 N1 - http://dx.doi.org/10.1016/S0166-5316(99)00058-9 SP - 61 EP - 80 ER - TY - JOUR A1 - Fiedler, Thomas M. A1 - Orzada, Stephan A1 - Flöser, Martina A1 - Rietsch, Stefan H. G. A1 - Schmidt, Simon A1 - Stelter, Jonathan K. A1 - Wittrich, Marco A1 - Quick, Harald H. A1 - Bitz, Andreas A1 - Ladd, Mark E. T1 - Performance and safety assessment of an integrated transmitarray for body imaging at 7 T under consideration of specificabsorption rate, tissue temperature, and thermal dose JF - NMR in Biomedicine N2 - In this study, the performance of an integrated body-imaging array for 7 T with 32 radiofrequency (RF) channels under consideration of local specific absorption rate (SAR), tissue temperature, and thermal dose limits was evaluated and the imaging performance was compared with a clinical 3 T body coil. Thirty-two transmit elements were placed in three rings between the bore liner and RF shield of the gradient coil. Slice-selective RF pulse optimizations for B1 shimming and spokes were performed for differently oriented slices in the body under consideration of realistic constraints for power and local SAR. To improve the B1+ homogeneity, safety assessments based on temperature and thermal dose were performed to possibly allow for higher input power for the pulse optimization than permissible with SAR limits. The results showed that using two spokes, the 7 T array outperformed the 3 T birdcage in all the considered regions of interest. However, a significantly higher SAR or lower duty cycle at 7 T is necessary in some cases to achieve similar B1+ homogeneity as at 3 T. The homogeneity in up to 50 cm-long coronal slices can particularly benefit from the high RF shim performance provided by the 32 RF channels. The thermal dose approach increases the allowable input power and the corresponding local SAR, in one example up to 100 W/kg, without limiting the exposure time necessary for an MR examination. In conclusion, the integrated antenna array at 7 T enables a clinical workflow for body imaging and comparable imaging performance to a conventional 3 T clinical body coil. KW - body imaging at 7 T MRI KW - thermal dose KW - tissue temperature KW - transmit antenna arrays Y1 - 2022 U6 - http://dx.doi.org/10.1002/nbm.4656 SN - 0952-3480 (Print) SN - 1099-1492 (Online) VL - 35 IS - 5 SP - 1 EP - 17 PB - Wiley ER - TY - JOUR A1 - Schuba, Marko T1 - Performance Analysis of Reliable Multicast Mechanisms for Widely Spread Distributed Applications in the Internet JF - International Conference on Parallel and Distributed Processing Techniques and Applications : PDPTA '99 ; June 28 - July 1, 1999, Las Vegas, Nevada, USA / ed.: Hamid R. Arabnia Y1 - 1999 SN - 1892512157 SP - 1 EP - 7 ER - TY - JOUR A1 - Mühl, Thomas A1 - Schwarz, Michael T1 - Pegel- und Dämpfungsmessung an Wellenlängenmultiplex-Systemen und -Komponenten JF - Nachrichtentechnische Zeitschrift. 46 (1993), H. 1 Y1 - 1993 SN - 0027-707X SP - 36 EP - 38 ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Geittner, P. T1 - PCVD hybrid technology for single mode fibres. Hagemann, H. J.; Geittner, P. JF - Proceedings : papers presented at: the 8th Annual European Fibre Optic Communications and Local Area Networks Exposition Y1 - 1990 N1 - EFOC LAN <8, 1990, München> SP - 67 EP - 72 ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Geittner, P. A1 - Warnier, J. A1 - Wilson, H. T1 - PCVD at high deposition rates. Geittner, P.; Hagemann, H. J.; Warnier, J.; Wilson, H. JF - Journal of Lightwave Technology (J-LT) / Institute of Electrical and Electronics Engineers (IEEE). 4 (1986), H. 7 Y1 - 1986 SN - 0733-8724 SP - 818 EP - 822 ER - TY - JOUR A1 - Scholl, Ingrid A1 - Conradi, Helmut A1 - Wirtz, D. A1 - Spreckelsen, Cord T1 - OrthoDocs - Ein modellbasiertes Werkzeug zur Erstellung orthopädischer Lerndokumente. Conradi, Helmar; Wirtz, D.; Spreckelsen, Cord; Scholl, Ingrid; Kreutz, Reinhard; Forst, R.; Spitzer, Klaus JF - Medizinische Informatik, Biometrie und Epidemiologie, GMDS '96, 41. Jahrestagung der GMDS, Bonn, September 1996 Y1 - 1997 SN - 3820812954 SP - 169 EP - 173 PB - MVV, Medizin-Verl. CY - München ER - TY - JOUR A1 - Scholl, Ingrid A1 - Kreutz, Reinhard A1 - Conradi, Helmut A1 - Spitzer, Klaus T1 - Orientierungs- und Benutzerunterstützung in Web-Dokumenten. Kreutz, Reinhard; Conradi, Helmut; Scholl, Ingrid; Spitzer, Klaus JF - Informatik '97 : Informatik als Innovationsmotor ; 27. Jahrestagung der Gesellschaft für Informatik Aachen, 24. - 26. September 1997 / Hrsg.: Matthias Jarke ... Y1 - 1997 SN - 3-540-63066-X SP - 516 EP - 517 PB - Springer CY - Berlin ER - TY - JOUR A1 - Köhler, Klemens A1 - Wolf, Martin T1 - Organisatorische Maßnahmen zu Erhöhung der IT Sicherheit – Empfehlungen aus der Perspektive der Konflikttheorie N2 - Die NATO definiert den Cyberspace als die "Umgebung, die durch physische und nicht-physische Bestandteile zum Speichern, Ändern, und Austauschen von Daten mit Hilfe von Computer-Netzwerken" [NATO CCDCOE]. Darüber hinaus ist es ein Medium menschlicher Interaktion. IT Angriffe sind feindselige, nichtkooperative Interaktionen, die mittels Konflikttheorie beschrieben werden können. Durch die Anwendung dieses Gedankengebäudes auf IT Sicherheit von Organisationen können eine Reihe von Verbesserungen in Unternehmen identifiziert werden. Y1 - 2020 IS - Preprint ER - TY - JOUR A1 - Ferrein, Alexander A1 - Böhnstedt, Lutz A1 - Lakemeyer, Gerhard T1 - Options in readylog reloaded -- generating decision-theoretic plan libraries in golog / Böhnstedt, Lutz ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - KI 2007: advances in artificial intelligence : 30th Annual German Conference on AI, KI 2007, Osnabrück, Germany, September 10 - 13, 2007 ; proceedings Y1 - 2007 SN - 978-3-540-74564-8 N1 - Lecture Notes in Computer Science ; 4667 SP - 352 EP - 366 PB - Springer CY - Berlin ER - TY - GEN A1 - Alt, Helmut T1 - Optionen einer bezahlbaren Energieversorgung „Vision versus Realismus" : Beitrag für KTG Kongress: vom 4. bis 6. Mai 2010, Berlin Y1 - 2010 SP - 1 EP - 10 ER - TY - JOUR A1 - Benkner, Thorsten T1 - Optimum Transmission Power in High Capacity Umbrella Cell Systems JF - Multiaccess, mobility and teletraffic : advances in wireless networks ; [proceedings of the Third Workshop on Multiaccess, Mobility and Teletraffic for Personal Communications held in December 1997 in Melbourne, Australia] / ed. by David Everitt ... Y1 - 1998 SN - 0-7923-8091-6 N1 - Workshop on Multiaccess, Mobility and Teletraffic for Personal Communications <3, 1997, Melbourne> SP - 221 EP - 232 PB - Kluwer CY - Boston, Mass. [u.a.] ER -