TY  - JOUR
A1  - Artmann, Gerhard
T1  - Microscopic photometric quantification of stiffness and relaxation time of red blood cells in a flow chamber. Artmann, Gerhard Michael
JF  - Biorheology. 32 (1995), H. 5
Y1  - 1995
SN  - 0006-355x
SP  - 553
EP  - 570
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
T1  - Cellular engineering - a challenge for engineers? / Artmann, G. M.
JF  - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1
Y1  - 2000
SN  - 1862-278X
SP  - 449
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Burns, Laura
A1  - Canaves, Jaume M.
A1  - Temiz Artmann, Aysegül
T1  - Circular dichroism spectra of human hemoglobin reveal a reversible structural transition at body temperature
JF  - European Biophysics Journal. 33 (2004), H. 6
Y1  - 2004
SN  - 1432-1017
SP  - 490
EP  - 496
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Bäumler, H.
A1  - Voigt, A.
A1  - Mitlöhner, R. [u.a.]
T1  - Plastic behaviour of polyelectrolyte microcapsules derived from colloid templates. Bäumler, H., Artmann, Gerhard Michael; Voigt, A., Mitlöhner, R., Neu, B., Kiesewetter, H.
JF  - Journal of Microencapsulation. 17 (2000), H. 5
Y1  - 2000
SN  - 1464-5246
SP  - 651
EP  - 655
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Linder, Peter
A1  - Porst, Dariusz
T1  - Mechanism of haemoglobin sensing body temperature
JF  - Tissue Engineering Part A. 14 (2008), H. 5
Y1  - 2008
SN  - 1937-3341
N1  - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal
SP  - 754
EP  - 754
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Zerlin, Kay
A1  - Maggakis-Kelemen, Christina
A1  - Linder, Peter
A1  - Porst, Dariusz
A1  - Kayser, Peter
A1  - Stadler, David
A1  - Dikta, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Hemoglobin senses body temperature
JF  - European Biophysics Journal
Y1  - 2009
SN  - 0175-7571
VL  - 38
IS  - 5
SP  - 589
EP  - 600
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Gorbatenkova, E. A.
A1  - Panasenko, O. M.
T1  - Hypochlorous acid and human blood low density lipoproteins modified by hypochlorous acid increase erythrocyte adhesion to endothelial cells. Gorbatenkova, E. A.; Artmann, Gerhard Michael; Panasenko, O. M.
JF  - Membrane and cell biology. 13 (2000), H. 4
Y1  - 2000
SN  - 1023-6597
SP  - 537
EP  - 546
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Grebe, R.
A1  - Homrighausen, A.
A1  - Wolff, H.
A1  - [u.a.], 
T1  - Response of normal and diabetic erythrocytes to membrane deformation by chemical and mechanical forces. Artmann, Gerhard Michael; Grebe, R.; Homrighausen, A.; Wolff, H.; Teitel, P.; Schmid-Schönbein, H.
JF  - 12. Jahrestagung der Gesellschaft für Mikrozirkulation
Y1  - 1988
SP  - 196
EP  - 200
PB  - Karger [u.a.]
CY  - Basel [u.a.]
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Hovav, T.
A1  - Goldfarb, A.
A1  - Yedgar, S. [u.a.]
T1  - Enhanced adherence of beta-thalassaemic erythrocytes to endothelial cells. Hovav, T., Goldfarb, A.; Artmann, Gerhard Michael, Yedgar, S.; Barstein, G.
JF  - British Journal of Haematology. 106 (1999), H. 1
Y1  - 1999
SN  - 1365-2141
SP  - 178
EP  - 181
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Hueck, I. S.
A1  - Hollweg, H. G.
A1  - Schmid-Schönbein, G. W.
T1  - Chlorpromazine modulates the Morphological Macro- and Microstructure of Endothelial Cells. Hueck, I. S.; Hollweg, H. G.; Schmid-Schönbein, G. W.; Artmann, Gerhard Michael
JF  - American Journal of Physiology. Cell Physiology. 278 (2000), H. 5
Y1  - 2000
SN  - 1522-1563
N1  - Zählung: C873- C878
SP  - 873
EP  - 878
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Hueck, Isgard S.
A1  - Rossiter, Katharine
A1  - Schmid-Schönbein, Geert W.
T1  - Fluid Shear Attenuates Endothelial Pseudopodia Formation into the Capillary Lumen / Hueck, Isgard S. ; Rossiter, Katharine ; Artman, Gerhard M. ; Schmid-Schönbein, Geert W.
JF  - Microcirculation. 15 (2008), H. 6
Y1  - 2008
SN  - 1549-8719
SP  - 531
EP  - 542
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Chien, S.
T1  - Temperature transition of human hemoglobin at body temperature: effects of calcium. Kelemen, C.; Chien, S.; Artmann, Gerhard Michael
JF  - Biophysical journal. 80 (2001), H. 6
Y1  - 2001
SN  - 1542-0086
SP  - 2622
EP  - 2630
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Porst, Dariusz
A1  - Büldt, G.
T1  - Cellular engineering: Crash tests an menschlichen Erythrozyten geben Aufschluß über versteckte Materialeigenschaften zellulärer Proteine / Artmann, G. M. ; Kelemen, Ch. ; Porst, D. ; Büldt, G. ; Chien, Shu
JF  - Biomedizinische Technik / Biomedical Engineering. 43 (1998), H. s1
Y1  - 1998
SN  - 1862-278
SP  - 446
EP  - 447
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, Christina
A1  - Porst, Dariusz
A1  - Büldt, G. [u.a.]
T1  - Temperature transitions of protein properties in human red blood cells. Artmann, Gerhard Michael, Kelemen, Christina; Porst, D.; Büldt, G.; Chien, S.
JF  - Biophysical Journal. 75 (1998), H. 6
Y1  - 1998
SN  - 1542-0086
N1  - http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1299989&blobtype=pdf
SP  - 3179
EP  - 3183
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Keller, U.
A1  - Haas, J.
A1  - Amort, U.
A1  - Zang, Werner
A1  - Karschies, S.
T1  - Technik und ausgewählte Applikationen eines Membranbioassays roter Blutzellen
JF  - Biomedizinische Technik = Biomedical engineering. 36 (1991)
Y1  - 1991
SN  - 0013-5585
VL  - 36
IS  - S1
SP  - 450
EP  - 451
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Li, Anlan
T1  - Dihydroergocryptine maintains erythrocyte fluidity in acidotic and hyperosmolar suspensions modelling hypoxic and ischemic microcirculation. Li, Anlan; Artmann, Gerhard Michael
JF  - Clinical Hemorheology. 15 (1994), H. 2
Y1  - 1994
SN  - 0271-5198
SP  - 133
EP  - 146
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Li, Anlan
A1  - Seipelt, H.
A1  - Müller, C. [u.a.]
T1  - Effects of salicylic acid derivatives on red blood cell membranes. Li, Anlan; Seipelt, H.; Müller, C.;Shi, Yong de; Artmann, Gerhard Michael
JF  - Pharmacology and Toxicology. 85 (1999)
Y1  - 1999
SN  - 0902-9938
SP  - 206
EP  - 211
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Li, Anlan
A1  - Ziemer, J.
A1  - Schneider, G. [u.a.]
T1  - A photometric method to analyze induced erythrocyte shape changes. Artmann, Gerhard Michael; Li, Anlan; Ziemer, J.; Schneider, G.; Sahm, U.: ; Ziemer, J.; Schneider, G.; Sahm, U.
JF  - Biorheology. 33 (1996), H. 3
Y1  - 1996
SN  - 0006-355x
SP  - 251
EP  - 265
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Montanus, M.
A1  - Teitel, P.
T1  - Die photometrische Kapillaraggregation- ein neues Verfahren zur Messung der Erythrozytenaggregation. Montanus, M.; Artmann, Gerhard Michael; Teitel, P.
JF  - Biomedizinische Technik = Biomedical engineering. 36 (1991)
Y1  - 1991
SN  - 0013-5585
SP  - 213
EP  - 215
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schikarsky, C.
T1  - Ginkgo Biloba extract (EGb 761) protects red blood cells from oxidative damage. Artmann, Gerhard Michael; Schikarsky, C.
JF  - Clinical Hemorheology. 13 (1993), H. 4
Y1  - 1993
SN  - 0271-5198
SP  - 529
EP  - 539
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schmid-Schönbein, H.
T1  - The microscope-photometrical-monolayer-technique- a new principle for analyzing the distribution of rheological responses in pathological and experimentally modified red cell populations. Artmann, Gerhard Michael; Schmid-Schönbein, H.
JF  - Microcirculation, an update : proceedings of the Fourth World Congress for Microcirculation, Tokyo, Japan, July 26-30, 1987
Y1  - 1987
SN  - 0444809511
N1  - World Congress for Microcirculation (4, 1987, Tokyo;); International congress series ; 755
SP  - 475
EP  - 477
PB  - Excerpta Medica
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schmid-Schönbein, H.
A1  - Grebe, R.
A1  - Teitel, P. [u.a.]
T1  - Restoration of Microsieve Filterability of Human Red Cells After Exposure to Hyperosmolarity and Lactazidosis: Effect of Vinpocetine. Schmid-Schönbein, H.; Grebe, R.; Teitel, P.; Artmann, Gerhard Michael, Eschweiler, H.; Schröder, Susanne
JF  - Drug Development Research. 14 (1988), H. 3-4
Y1  - 1988
SN  - 1098-2299
N1  - Abstracts frei unter:
SP  - 205
EP  - 211
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schmid-Schönbein, H.
A1  - Schröder, Susanne
A1  - Grebe, R. [u.a.]
T1  - Influence of Moxaverine-HCL on Membrane Curvature and Microsieve Filterability of Red Cells after Exposure to Hyperosmolarity and Lactacidosis. Schmid-Schönbein, H.; Schröder, Susanne; Grebe, R.; Artmann, Gerhard Michael, Eschweiler, H; Teitel, P.
JF  - Arzneimittelforschung. 38 (1988), H. 5
Y1  - 1988
SN  - 0004-4172
SP  - 710
EP  - 716
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Shi, Young de
A1  - Agosti, R.
A1  - Longhini, E.
T1  - A modified casson equation to characterize blood rheology for hypertension. Shi, Young de; Artmann, Gerhard Michael; Agosti, R.; Longhini, E.
JF  - Clinical Hemorheology Microcirculation. 19 (1998), H. 2
Y1  - 1998
SN  - 1386-0291
SP  - 115
EP  - 127
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Stache, O.
A1  - Königsfeld, J.
T1  - Temperaturabhängigkeit der Pseudopodienbildung und Rückbildung von Granulozyten / Stache, O. ; Königsfeld, J. ; Artmann, G. M.
JF  - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1
Y1  - 2000
SN  - 1862-278X
SP  - 450
EP  - 451
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Sung, K.-L. Paul
A1  - Horn, Thomas
A1  - Whittemore, Darren [u.a.]
T1  - Micropipette aspiration of human erythrocytes induces echinocytes via membrane phospholipid translocation. Artmann, Gerhard Michael; Sung, K.-L. Paul; Horn, Thomas; Whittemore, Darren; Norwich, Gerald; Chien, Shu
JF  - Biophysical journal. 72 (1997), H. 3
Y1  - 1997
SN  - 1542-0086
SP  - 1434
EP  - 1441
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Teitel, P.
A1  - Schmid-Schönbein, H.
T1  - Variable rheologische Antwort der Erythrozyten auf den Einfluß von Xantinderivaten (Coffein): Experimentelle Differenzierung von "Responders" und "Nonresponders"
JF  - 11. Jahrestagung der Gesellschaft für Mikrozirkulation
Y1  - 1987
SP  - 100
EP  - 105
PB  - Karger [u.a.]
CY  - Basel [u.a.]
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Trzewik, J.
A1  - Schmid-Schönbein, G. W.
T1  - Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Schönbein, G. W.
JF  - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1
Y1  - 2000
SN  - 1862-278X
SP  - 521
EP  - 522
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Trzewik, Jürgen
A1  - Ates, M.
T1  - A novel method to quantify mechanical tension in cell monolayers. Trzewik, Jürgen; Ates, M., Artmann, Gerhard Michael
JF  - Biomedizinische Technik. 47 (2002), H. Suppl. 1. Pt. 1
Y1  - 2002
SN  - 0013-5585
N1  - Druckausgabe unter 63 Z 47 vorhanden
SP  - 379
EP  - 381
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Trzewik, Jürgen
A1  - Mallipattu, S. K.
A1  - Delano, F. A. [u.a.]
T1  - Evidence for a second valve system in Lymphatics: Endothelial Microvalves. Trzewik, Jürgen; Mallipattu, S. K.; Artmann, Gerhard Michael; Delano, F. A.; Schmid-Schonbein, G. W
JF  - The FASEB Journal. 15 (2001)
Y1  - 2001
SN  - 1530-6860
SP  - 1711
EP  - 1717
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Vogel, A.
A1  - Zink, S.
A1  - Stache, O.
T1  - Entwicklung eines automatisierten, computergesteuerten Permeabilitätsanalysators zur Messung an Endothelzellen / Vogel, A. ; Zinke, S. ; Stache, O. ; Königsfeld, J. ; Artmann, G.
JF  - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1
Y1  - 2000
SN  - 1862-278X
SP  - 479
EP  - 480
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Witte, Ch.
T1  - Expertensystem für Personal Computer zur Strukturbestimmung des Circulus Arteriosus Willisii mittels transkranieller Dopplersonografie. Witte, Ch.; Artmann, Gerhard Michael
JF  - Biomedizinische Technik = Biomedical engineering. 36 (1991)
Y1  - 1991
SN  - 0013-5585
SP  - 228
EP  - 230
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zang, Werner
T1  - Fully automatic measurement of rheologic parameters of red blood cells = Laborautomat zur Messung mechanischer Eigenschaften roter Blutzellen
JF  - Biomedizinische Technik = Biomedical engineering. 35 (1990), H. Suppl. 3
Y1  - 1990
SN  - 0013-5585
SP  - 94
EP  - 96
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zang, Werner
T1  - Vollautomatische Messung rheologischer Parameter roter Blutzellen
JF  - Biomedizinische Technik / Biomedical Engineering
Y1  - 1990
SN  - 0013-5585
VL  - 35
IS  - S3
SP  - 94
EP  - 96
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zerlin, Kay
A1  - Digel, Ilya
T1  - Hemoglobin Senses Body Temperature
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 415
EP  - 447
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zerlin, Kay
A1  - Digel, Ilya
A1  - Stadler, Andreas M.
T1  - Physical discontinuities at body temperature in human red blood cells / Artmann, GM ; Zerlin, K ; Digel, I ; Stadler, A ; Zaccai, G ; Temiz, AA
JF  - Tissue Engineering. 13 (2007), H. 7
Y1  - 2007
SN  - 1076-3279
N1  - TERMIS-EU Meeting Abstracts London, UK September 4–7, 2007
SP  - 1778
EP  - 1778
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zhou-Stache, J.
A1  - Buettner, R.
A1  - Mittermayer, C. [u.a.]
T1  - Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K.
JF  - Medical and Biological Engineering and Computing. 40 (2002), H. 6
Y1  - 2002
SN  - 0140-0118
SP  - 698
EP  - 703
ER  - 
TY  - JOUR
A1  - Atlas, Glen
A1  - Brealey, David
A1  - Dhar, Sunil
A1  - Dikta, Gerhard
A1  - Singer, Meryvn
T1  - Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting
JF  - Journal of clinical monitoring and computing
N2  - The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient’s clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated.
KW  - Acceleration
KW  - Velocity
KW  - Kinetic energy
KW  - Force
KW  - Compliance
KW  - Afterload
KW  - Contractility
KW  - Volume status
KW  - Esophageal Doppler monitor
Y1  - 2012
SN  - 1573-2614
U6  - http://dx.doi.org/10.1007/s10877-012-9386-5
IS  - 26
SP  - 473
EP  - 482
PB  - Springer Nature
CY  - London
ER  - 
TY  - JOUR
A1  - Attar, Mandana Hossein Zadeh
A1  - Merk, Hans F.
A1  - Kotliar, Konstantin
A1  - Wurpts, Gerda
A1  - Röseler, Stefani
A1  - Moll-Slodowy, Silke
A1  - Plange, Johann
A1  - Baron, Jens Malte
A1  - Balakirski, Galina
T1  - The CD63 basophil activation test as a diagnostic tool for assessing autoimmunity in patients with chronic spontaneous urticaria
JF  - European Journal of Dermatology
Y1  - 2019
U6  - http://dx.doi.org/10.1684/ejd.2019.3680
VL  - 29
IS  - 6
SP  - 614
EP  - 618
ER  - 
TY  - JOUR
A1  - Auffray, E.
A1  - Bruyndonckx, P.
A1  - Devroede, O.
A1  - Fedorov, A.
A1  - Ziemons, Karl
T1  - The ClearPET project
JF  - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
N2  - The Crystal Clear Collaboration has designed and is building a high-resolution small animal PET scanner. The design is based on the use of the Hamamatsu R7600-M64 multi-anode photomultiplier tube and a LSO/LuYAP phoswich matrix with one to one coupling between the crystals and the photo-detector. The complete system will have 80 PM tubes in four rings with an inner diameter of 137 mm and an axial field of view of 110 mm. The PM pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. Simulations, and measurements a 2×4 module test set-up predict a spatial resolution of 1.5 mm in the centre of the field of view and a sensitivity of 5.9% for a point source in the centre of the field of view.
Y1  - 2004
SN  - 0168-9002
N1  - Proceedings of the 2nd International Conference on Imaging Technologies in Biomedical Sciences
VL  - 527
IS  - 1-2
SP  - 171
EP  - 174
ER  - 
TY  - JOUR
A1  - Ayala, Rafael Ceja
A1  - Harris, Isaac
A1  - Kleefeld, Andreas
A1  - Pallikarakis, Nikolaos
T1  - Analysis of the transmission eigenvalue problem with two conductivity parameters
JF  - Applicable Analysis
N2  - In this paper, we provide an analytical study of the transmission eigenvalue problem with two conductivity parameters. We will assume that the underlying physical model is given by the scattering of a plane wave for an isotropic scatterer. In previous studies, this eigenvalue problem was analyzed with one conductive boundary parameter whereas we will consider the case of two parameters. We prove the existence and discreteness of the transmission eigenvalues as well as study the dependence on the physical parameters. We are able to prove monotonicity of the first transmission eigenvalue with respect to the parameters and consider the limiting procedure as the second boundary parameter vanishes. Lastly, we provide extensive numerical experiments to validate the theoretical work.
KW  - Transmission Eigenvalues
KW  - Conductive Boundary Condition
KW  - Inverse Scattering
Y1  - 2023
U6  - http://dx.doi.org/10.1080/00036811.2023.2181167
SN  - 0003-6811
PB  - Taylor & Francis
ER  - 
TY  - JOUR
A1  - Balakirski, Galina
A1  - Kotliar, Konstantin
A1  - Pauly, Karolin J.
A1  - Krings, Laura K.
A1  - Rübben, Albert
A1  - Baron, Jens M.
A1  - Schmitt, Laurenz
T1  - Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience
JF  - Dermatologic Surgery
N2  - BACKGROUND 
Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited.

PATIENTS AND METHODS 
All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records.

RESULTS 
The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7% (19/284) of the cases. In 95% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients.

CONCLUSION 
According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients.

The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects.

Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13% to 29% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis.

To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients.
Y1  - 2018
U6  - http://dx.doi.org/10.1097/DSS.0000000000001615
IS  - 44 (12)
SP  - 1525
EP  - 1536
PB  - Wolters Kluwer
ER  - 
TY  - JOUR
A1  - Ball, Christopher Stephen
A1  - Vögele, Stefan
A1  - Grajewski, Matthias
A1  - Kuckshinrichs, Wilhelm
T1  - E-mobility from a multi-actor point of view: Uncertainties and their impacts
JF  - Technological Forecasting and Social Change
Y1  - 2021
SN  - 0040-1625
U6  - http://dx.doi.org/10.1016/j.techfore.2021.120925
VL  - 170
IS  - Art. 120925
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bandodkar, Amay J.
A1  - Molinnus, Denise
A1  - Mirza, Omar
A1  - Guinovart, Tomas
A1  - Windmiller, Joshua R.
A1  - Valdes-Ramirez, Gabriela
A1  - Andrade, Francisco J.
A1  - Schöning, Michael Josef
A1  - Wang, Joseph
T1  - Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring
JF  - Biosensors and bioelectronics
N2  - This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains.
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.bios.2013.11.039
SN  - 1873-4235 (E-Journal); 0956-5663 (Print)
VL  - 54
SP  - 603
EP  - 609
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - A goodness-of-fit test for the compound Poisson exponential model
JF  - Journal of Multivariate Analysis
N2  - On the basis of bivariate data, assumed to be observations of independent copies of a random vector (S,N), we consider testing the hypothesis that the distribution of (S,N) belongs to the parametric class of distributions that arise with the compound Poisson exponential model. Typically, this model is used in stochastic hydrology, with N as the number of raindays, and S as total rainfall amount during a certain time period, or in actuarial science, with N as the number of losses, and S as total loss expenditure during a certain time period. The compound Poisson exponential model is characterized in the way that a specific transform associated with the distribution of (S,N) satisfies a certain differential equation. Mimicking the function part of this equation by substituting the empirical counterparts of the transform we obtain an expression the weighted integral of the square of which is used as test statistic. We deal with two variants of the latter, one of which being invariant under scale transformations of the S-part by fixed positive constants. Critical values are obtained by using a parametric bootstrap procedure. The asymptotic behavior of the tests is discussed. A simulation study demonstrates the performance of the tests in the finite sample case. The procedure is applied to rainfall data and to an actuarial dataset. A multivariate extension is also discussed.
KW  - Bootstrapping
KW  - Collective risk model
Y1  - 2022
U6  - http://dx.doi.org/10.1016/j.jmva.2022.105154
SN  - 0047-259X
SN  - 1095-7243
VL  - 195
IS  - Article 105154
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - On Hotelling’s T² test in a special paired sample case
JF  - Communications in Statistics - Theory and Methods
N2  - In a special paired sample case, Hotelling’s T² test based on the differences of the paired random vectors is the likelihood ratio test for testing the hypothesis that the paired random vectors have the same mean; with respect to a special group of affine linear transformations it is the uniformly most powerful invariant test for the general alternative of a difference in mean. We present an elementary straightforward proof of this result. The likelihood ratio test for testing the hypothesis that the covariance structure is of the assumed special form is derived and discussed. Applications to real data are given.
KW  - complete block symmetry
KW  - Hotelling’s T² test
KW  - likelihood ratio test
KW  - uniformly most powerful invariant test
Y1  - 2017
U6  - http://dx.doi.org/10.1080/03610926.2017.1408828
SN  - 1532-415X
VL  - 48
IS  - 2
SP  - 257
EP  - 267
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - Hotelling’s T² tests in paired and independent survey samples: An efficiency comparison
JF  - Journal of Multivariate Analysis
N2  - Hotelling’s T² tests in paired and independent survey samples are compared using the traditional asymptotic efficiency concepts of Hodges–Lehmann, Bahadur and Pitman, as well as through criteria based on the volumes of corresponding confidence regions. Conditions characterizing the superiority of a procedure are given in terms of population canonical correlation type coefficients. Statistical tests for checking these conditions are developed. Test statistics based on the eigenvalues of a symmetrized sample cross-covariance matrix are suggested, as well as test statistics based on sample canonical correlation type coefficients.
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jmva.2016.11.004
SN  - 0047-259X
VL  - 2017
IS  - 154
SP  - 177
EP  - 198
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - On an independence test approach to the goodness-of-fit problem
JF  - Journal of Multivariate Analysis
N2  - Let X₁,…,Xₙ be independent and identically distributed random variables with distribution F. Assuming that there are measurable functions f:R²→R and g:R²→R characterizing a family F of distributions on the Borel sets of R in the way that the random variables f(X₁,X₂),g(X₁,X₂) are independent, if and only if F∈F, we propose to treat the testing problem H:F∈F,K:F∉F by applying a consistent nonparametric independence test to the bivariate sample variables (f(Xᵢ,Xⱼ),g(Xᵢ,Xⱼ)),1⩽i,j⩽n,i≠j. A parametric bootstrap procedure needed to get critical values is shown to work. The consistency of the test is discussed. The power performance of the procedure is compared with that of the classical tests of Kolmogorov–Smirnov and Cramér–von Mises in the special cases where F is the family of gamma distributions or the family of inverse Gaussian distributions.
KW  - Goodness-of-fit test
KW  - Independence test
KW  - Parametric bootstrap
KW  - Vapnik–Čhervonenkis class
KW  - Gamma distribution
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.jmva.2015.05.013
SN  - 0047-259X
VL  - 2015
IS  - 140
SP  - 193
EP  - 208
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - On an asymptotic relative efficiency concept based on expected volumes of confidence regions
JF  - Statistics - A Journal of Theoretical and Applied Statistic
N2  - The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.
KW  - Volume of confidence regions
KW  - asymptotic relative efficiency
KW  - likelihood ratio test
KW  - multivariate normal distribution
KW  - multinomial distribution
Y1  - 2019
U6  - http://dx.doi.org/10.1080/02331888.2019.1683560
SN  - 1029-4910
VL  - 53
IS  - 6
SP  - 1396
EP  - 1436
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
A1  - Thiele, Jan Philipp
T1  - Statistical inference for L²-distances to uniformity
JF  - Computational Statistics
N2  - The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study.
KW  - Integrated empirical distribution (survival) function
KW  - Goodness-of-fit tests for uniformity
KW  - Numerical inversion of Laplace transforms
KW  - Coverage probability
KW  - Equivalence test
Y1  - 2018
U6  - http://dx.doi.org/10.1007/s00180-018-0820-0
SN  - 1613-9658
VL  - 2018
IS  - 33
SP  - 1863
EP  - 1896
PB  - Springer
CY  - Berlin
ER  -