TY - JOUR A1 - Gossmann, Matthias A1 - Thomas, Ulrich A1 - Horváth, András A1 - Dragicevic, Elena A1 - Stoelzle-Feix, Sonja A1 - Jung, Alexander A1 - Raman, Aravind Hariharan A1 - Staat, Manfred A1 - Linder, Peter T1 - A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions JF - Journal of Pharmacological and Toxicological Methods Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.vascn.2020.106843 VL - 105 IS - Article 106843 PB - Elsevier CY - New York, NY ER - TY - CHAP A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Introduction to Additive Manufacturing T2 - 3D Printing of Optical Components N2 - Additive manufacturing (AM) works by creating objects layer by layer in a manner similar to a 2D printer with the “printed” layers stacked on top of each other. The layer-wise manufacturing nature of AM enables fabrication of freeform geometries which cannot be fabricated using conventional manufacturing methods as a one part. Depending on how each layer is created and bonded to the adjacent layers, different AM methods have been developed. In this chapter, the basic terms, common materials, and different methods of AM are described, and their potential applications are discussed. KW - Additive manufacturing KW - 3D printing KW - Digital manufacturing KW - Rapid prototyping KW - Rapid manufacturing Y1 - 2020 SN - 978-3-030-58960-8 U6 - http://dx.doi.org/10.1007/978-3-030-58960-8_1 SP - 1 EP - 22 PB - Springer CY - Cham ER - TY - CHAP A1 - Bozakov, Zdravko A1 - Sander, Volker T1 - OpenFlow: A Perspective for Building Versatile Networks T2 - Network-Embedded Management and Applications Y1 - 2013 SN - 978-1-4419-6769-5 U6 - http://dx.doi.org/10.1007/978-1-4419-6769-5_11 SP - 217 EP - 245 PB - Springer CY - New York, NY ER - TY - CHAP A1 - Götten, Falk A1 - Finger, Felix A1 - Braun, Carsten A1 - Havermann, Marc A1 - Bil, C. A1 - Gomez, F. T1 - Empirical Correlations for Geometry Build-Up of Fixed Wing Unmanned Air Vehicles T2 - APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018) N2 - The results of a statistical investigation of 42 fixed-wing, small to medium sized (20 kg−1000 kg) reconnaissance unmanned air vehicles (UAVs) are presented. Regression analyses are used to identify correlations of the most relevant geometry dimensions with the UAV’s maximum take-off mass. The findings allow an empirical based geometry-build up for a complete unmanned aircraft by referring to its take-off mass only. This provides a bridge between very early design stages (initial sizing) and the later determination of shapes and dimensions. The correlations might be integrated into a UAV sizing environment and allow designers to implement more sophisticated drag and weight estimation methods in this process. Additional information on correlation factors for a rough drag estimation methodology indicate how this technique can significantly enhance the accuracy of early design iterations. KW - Unmanned Air Vehicle KW - Geometry KW - Correlations KW - Statistics KW - Drag Y1 - 2019 SN - 978-981-13-3305-7 U6 - http://dx.doi.org/10.1007/978-981-13-3305-7_109 N1 - APISAT 2018 - Asia-Pacific International Symposium on Aerospace Technology. 16-18 October 2018. Chengdu, China. Lecture Notes in Electrical Engineering (LNEE, volume 459) SP - 1365 EP - 1381 PB - Springer CY - Singapore ER - TY - CHAP A1 - Finger, Felix A1 - Götten, Falk A1 - Braun, Carsten A1 - Bil, C. T1 - On Aircraft Design Under the Consideration of Hybrid-Electric Propulsion Systems T2 - APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018) N2 - A hybrid-electric propulsion system combines the advantages of fuel-based systems and battery powered systems and offers new design freedom. To take full advantage of this technology, aircraft designers must be aware of its key differences, compared to conventional, carbon-fuel based, propulsion systems. This paper gives an overview of the challenges and potential benefits associated with the design of aircraft that use hybrid-electric propulsion systems. It offers an introduction of the most popular hybrid-electric propulsion architectures and critically assess them against the conventional and fully electric propulsion configurations. The effects on operational aspects and design aspects are covered. Special consideration is given to the application of hybrid-electric propulsion technology to both unmanned and vertical take-off and landing aircraft. The authors conclude that electric propulsion technology has the potential to revolutionize aircraft design. However, new and innovative methods must be researched, to realize the full benefit of the technology. KW - Hybrid-electric aircraft KW - Aircraft design KW - Design rules KW - Green aircraft Y1 - 2019 SN - 978-981-13-3305-7 U6 - http://dx.doi.org/10.1007/978-981-13-3305-7_99 N1 - APISAT 2018 - Asia-Pacific International Symposium on Aerospace Technology. 16-18 October 2018. Chengdu, China. Lecture Notes in Electrical Engineering (LNEE, volume 459) SP - 1261 EP - 1272 PB - Springer CY - Singapore ER - TY - JOUR A1 - Conzen, Catharina A1 - Albanna, Walid A1 - Weiss, Miriam A1 - Kürten, David A1 - Vilser, Walthard A1 - Kotliar, Konstantin A1 - Zäske, Charlotte A1 - Clusmann, Hans A1 - Schubert, Gerrit Alexander T1 - Vasoconstriction and Impairment of Neurovascular Coupling after Subarachnoid Hemorrhage: a Descriptive Analysis of Retinal Changes JF - Translational Stroke Research N2 - Impaired cerebral autoregulation and neurovascular coupling (NVC) contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Retinal vessel analysis (RVA) allows non-invasive assessment of vessel dimension and NVC hereby demonstrating a predictive value in the context of various neurovascular diseases. Using RVA as a translational approach, we aimed to assess the retinal vessels in patients with SAH. RVA was performed prospectively in 24 patients with acute SAH (group A: day 5–14), in 11 patients 3 months after ictus (group B: day 90 ± 35), and in 35 age-matched healthy controls (group C). Data was acquired using a Retinal Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and NVC using flicker-light excitation. Diameter of retinal vessels—central retinal arteriolar and venular equivalent—was significantly reduced in the acute phase (p < 0.001) with gradual improvement in group B (p < 0.05). Arterial NVC of group A was significantly impaired with diminished dilatation (p < 0.001) and reduced area under the curve (p < 0.01) when compared to group C. Group B showed persistent prolonged latency of arterial dilation (p < 0.05). Venous NVC was significantly delayed after SAH compared to group C (A p < 0.001; B p < 0.05). To our knowledge, this is the first clinical study to document retinal vasoconstriction and impairment of NVC in patients with SAH. Using non-invasive RVA as a translational approach, characteristic patterns of compromise were detected for the arterial and venous compartment of the neurovascular unit in a time-dependent fashion. Recruitment will continue to facilitate a correlation analysis with clinical course and outcome. Y1 - 2018 U6 - http://dx.doi.org/10.1007/s12975-017-0585-8 SN - 1868-601X IS - 9 SP - 284 EP - 293 PB - Springer Nature CY - Cham ER - TY - CHAP A1 - Chavez Bermudez, Victor Francisco A1 - Wollert, Jörg T1 - Arduino based Framework for Rapid Application Development of a Generic IO-Link interface T2 - Kommunikation und Bildverarbeitung in der Automation N2 - The implementation of IO-Link in the automation industry has increased over the years. Its main advantage is it offers a digital point-to-point plugand-play interface for any type of device or application. This simplifies the communication between devices and increases productivity with its different features like self-parametrization and maintenance. However, its complete potential is not always used. The aim of this paper is to create an Arduino based framework for the development of generic IO-Link devices and increase its implementation for rapid prototyping. By generating the IO device description file (IODD) from a graphical user interface, and further customizable options for the device application, the end-user can intuitively develop generic IO-Link devices. The peculiarity of this framework relies on its simplicity and abstraction which allows to implement any sensor functionality and virtually connect any type of device to an IO-Link master. This work consists of the general overview of the framework, the technical background of its development and a proof of concept which demonstrates the workflow for its implementation. Y1 - 2020 SN - 978-3-662-59895-5 SN - 978-3-662-59894-8 U6 - http://dx.doi.org/10.1007/978-3-662-59895-5_2 N1 - Teil der Buchserie "Technologien für die intelligente Automation" (TIA,volume 12) SP - 21 EP - 33 PB - Springer Vieweg CY - Berlin ER - TY - CHAP A1 - Gebhardt, Andreas A1 - Hoetter, Jan-Steffen T1 - Rapid Tooling T2 - CIRP Encyclopedia of Production Engineering Y1 - 2019 SN - 978-3-662-53120-4 U6 - http://dx.doi.org/10.1007/978-3-662-53120-4 SP - 39 EP - 52 PB - Springer CY - Berlin, Heidelberg ER - TY - CHAP A1 - Hofmann, Till A1 - Limpert, Nicolas A1 - Mataré, Viktor A1 - Ferrein, Alexander A1 - Lakemeyer, Gerhard T1 - Winning the RoboCup Logistics League with Fast Navigation, Precise Manipulation, and Robust Goal Reasoning T2 - RoboCup 2019: Robot World Cup XXIII. RoboCup Y1 - 2019 SN - 978-3-030-35699-6 U6 - http://dx.doi.org/10.1007/978-3-030-35699-6_41 N1 - Lecture Notes in Computer Science, vol 11531 SP - 504 EP - 516 PB - Springer CY - Cham ER - TY - JOUR A1 - Gazda, Quentin A1 - Maurischat, Andreas T1 - Special functions and Gauss-Thakur sums in higher rank and dimension Y1 - 2020 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Stulpe, Werner T1 - Pairwise coexistence of effects versus coexistence JF - Journal of Physics: Conference Series Y1 - 2020 U6 - http://dx.doi.org/10.1088/1742-6596/1638/1/012004 SN - 1742-6596 VL - 1638 IS - 012004 SP - 1 EP - 21 PB - IOP CY - Bristol ER - TY - CHAP A1 - Frantz, Cathy A1 - Binder, Matthias A1 - Busch, Konrad A1 - Ebert, Miriam A1 - Heinrich, Andreas A1 - Kaczmarkiewicz, Nadine A1 - Schlögl-Knothe, Bärbel A1 - Kunze, Tobias A1 - Schuhbauer, Christian A1 - Stetka, Markus A1 - Schwager, Christian A1 - Spiegel, Michael A1 - Teixeira Boura, Cristiano José A1 - Bauer, Thomas A1 - Bonk, Alexander A1 - Eisen, Stefan A1 - Funck, Bernhard T1 - Basic Engineering of a High Performance Molten Salt Tower Receiver System T2 - Solar Paces 2020 Y1 - 2020 SP - 1 EP - 10 ER - TY - CHAP A1 - Iomdina, Elena N. A1 - Kiseleva, Anna A. A1 - Kotliar, Konstantin A1 - Luzhnov, Petr V. T1 - Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing T2 - 2020 International Conference on Biomedical Innovations and Applications (BIA) Y1 - 2020 SN - 978-1-7281-7073-2 U6 - http://dx.doi.org/10.1109/BIA50171.2020.9244511 SP - 41 EP - 44 ER - TY - BOOK A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef ED - Yoshinobu, Tatsuo ED - Schöning, Michael Josef T1 - Light-addressing and chemical imaging technologies for electrochemical sensing Y1 - 2020 SN - 978-3-03943-029-1 U6 - http://dx.doi.org/10.3390/books978-3-03943-029-1 N1 - This book is a printed edition of the Special Issue Light-Addressing and Chemical Imaging Technologies for Electrochemical Sensing that was published in Sensors PB - MDPI CY - Basel ER - TY - CHAP A1 - Sildatke, Michael A1 - Karwanni, Hendrik A1 - Kraft, Bodo A1 - Schmidts, Oliver A1 - Zündorf, Albert T1 - Automated Software Quality Monitoring in Research Collaboration Projects T2 - ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops Y1 - 2020 U6 - http://dx.doi.org/10.1145/3387940.3391478 SP - 603 EP - 610 ER - TY - CHAP A1 - Ibanez-Sanchez, Gema A1 - Wolf, Martin T1 - Interactive Process Mining-Induced Change Management Methodology for Healthcare T2 - Interactive Process Mining in Healthcare N2 - The adoption of the Digital Health Transformation is a tremendous paradigm change in health organizations, which is not a trivial process in reality. For that reason, in this chapter, it is proposed a methodology with the objective to generate a changing culture in healthcare organisations. Such a change culture is essential for the successful implementation of any supporting methods like Interactive Process Mining. It needs to incorporate (mostly) new ways of team-based and evidence-based approaches for solving structural problems in a digital healthcare environment. KW - Methodology KW - Change culture KW - Lean thinking KW - Interactive process mining KW - Objective data Y1 - 2020 SN - 978-3-030-53993-1 (Online) SN - 978-3-030-53992-4 (Print) U6 - http://dx.doi.org/10.1007/978-3-030-53993-1_16 SP - 267 EP - 293 PB - Springer CY - Cham ER - TY - JOUR A1 - Malan, Leone A1 - Hamer, Mark A1 - Känel, Roland von A1 - Kotliar, Konstantin A1 - Wyk, Roelof D. van A1 - Lambert, Gavin W. A1 - Vilser, Walthard A1 - Ziemssen, Tjalf A1 - Schlaich, Markus P. A1 - Smith, Wayne A1 - Magnusson, Martin A1 - Wentzel, Annemarie A1 - Myburgh, Carlien E. A1 - Steyn, Hendrik S. A1 - Malan, Nico T. T1 - Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study JF - Cardiovascular Journal of Africa Y1 - 2020 U6 - http://dx.doi.org/10.5830/CVJA-2020-031 SN - 1680-0745 VL - 26 IS - 31 SP - 1 EP - 12 PB - Clinics Cardive Publishing CY - Durbanville ER - TY - JOUR A1 - Quittmann, Oliver J. A1 - Meskemper, Joshua A1 - Albracht, Kirsten A1 - Abel, Thomas A1 - Foitschik, Tina A1 - Strüder, Heiko K. T1 - Normalising surface EMG of ten upper-extremity muscles in handcycling: Manual resistance vs. sport-specific MVICs JF - Journal of Electromyography and Kinesiology N2 - Muscular activity in terms of surface electromyography (sEMG) is usually normalised to maximal voluntary isometric contractions (MVICs). This study aims to compare two different MVIC-modes in handcycling and examine the effect of moving average window-size. Twelve able-bodied male competitive triathletes performed ten MVICs against manual resistance and four sport-specific trials against fixed cranks. sEMG of ten muscles [M. trapezius (TD); M. pectoralis major (PM); M. deltoideus, Pars clavicularis (DA); M. deltoideus, Pars spinalis (DP); M. biceps brachii (BB); M. triceps brachii (TB); forearm flexors (FC); forearm extensors (EC); M. latissimus dorsi (LD) and M. rectus abdominis (RA)] was recorded and filtered using moving average window-sizes of 150, 200, 250 and 300 ms. Sport-specific MVICs were higher compared to manual resistance for TB, DA, DP and LD, whereas FC, TD, BB and RA demonstrated lower values. PM and EC demonstrated no significant difference between MVIC-modes. Moving average window-size had no effect on MVIC outcomes. MVIC-mode should be taken into account when normalised sEMG data are illustrated in handcycling. Sport-specific MVICs seem to be suitable for some muscles (TB, DA, DP and LD), but should be augmented by MVICs against manual/mechanical resistance for FC, TD, BB and RA. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.jelekin.2020.102402 SN - 1050-6411 VL - 51 IS - Article 102402 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Varga, Laszlo A1 - Davinson, Thomas A1 - Glorius, Jan A1 - Jurado, Beatrix A1 - Langer, Christoph A1 - Lederer-Woods, Claudia A1 - Litvinov, Yuri A. A1 - Reifarth, Rene A1 - Slavkovska, Zuzana A1 - Stöhlker, Thomas A1 - Woods, Phil J. A1 - Xing, Yuan Ming T1 - Towards background-free studies of capture reaction in a heavy-ion storage ring JF - Journal of Physics: Conference Series N2 - Stored and cooled, highly-charged ions offer unprecedented capabilities for precision studies in the realm of atomic, nuclear structure and astrophysics[1]. After the successful investigation of the 96Ru(p,7)97Rh reaction cross section in 2009[2], the first measurement of the 124Xe(p,7)125Cs reaction cross section has been performed with decelerated, fully-ionized 124Xe ions in 2016 at the Experimental Storage Ring (ESR) of GSI[3]. Using a Double Sided Silicon Strip Detector, introduced directly into the ultra-high vacuum environment of a storage ring, the 125Cs proton-capture products have been successfully detected. The cross section has been measured at 5 different energies between 5.5AMeV and 8AMeV, on the high energy tail of the Gamow-window for hot, explosive scenarios such as supernovae and X-ray binaries. The elastic scattering on the H2 gas jet target is the major source of background to count the (p,7) events. Monte Carlo simulations show that an additional slit system in the ESR in combination with the energy information of the Si detector will enable background free measurements of the proton-capture products. The corresponding hardware is being prepared and will increase the sensitivity of the method tremendously. Y1 - 2020 VL - 1668 IS - Art 012046 PB - IOP CY - Bristol ER - TY - JOUR A1 - Henriques, A. A1 - Jurado, B. A1 - Grieser, M. A1 - Denis-Petit, D. A1 - Chiron, T. A1 - Gaudefroy, L. A1 - Glorius, J. A1 - Langer, Christoph A1 - Litvinov, Yu. A. A1 - Mathieu, L. A1 - Meot, V. A1 - Perez-Sanchez, R. A1 - Pibernat, J. A1 - Reifarth, R. A1 - Roig, O. A1 - Thomas, B. A1 - Thomas, B. A. A1 - Thomas, J. C. A1 - Tsekhanovich, I. T1 - Indirect measurements of neutron cross-secti at heavy-ion storage rings JF - Journal of Physics: Conference Series N2 - Cross sections for neutron-induced reactions of short-lived nuclei are essential for nuclear astrophysics since these reactions in the stars are responsible for the production of most heavy elements in the universe. These reactions are also key in applied domains like energy production and medicine. Nevertheless, neutron-induced cross-section measurements can be extremely challenging or even impossible to perform due to the radioactivity of the targets involved. Indirect measurements through the surrogate-reaction method can help to overcome these difficulties. The surrogate-reaction method relies on the use of an alternative reaction that will lead to the formation of the same excited nucleus as in the neutron-induced reaction of interest. The decay probabilities (for fission, neutron and gamma-ray emission) of the nucleus produced via the surrogate reaction allow one to constrain models and the prediction of the desired neutron cross sections. We propose to perform surrogate reaction measurements in inverse kinematics at heavy-ion storage rings, in particular at the CRYRING@ESR of the GSI/FAIR facility. We present the conceptual idea of the most promising setup to measure for the first time simultaneously the fission, neutron and gamma-ray emission probabilities. The results of the first simulations considering the 238U(d,d') reaction are shown, as well as new technical developments that are being carried out towards this set-up. Y1 - 2020 U6 - http://dx.doi.org/10.1088/1742-6596/1668/1/012019 VL - 1668 IS - Art. 012019 PB - IOP CY - Bristol ER -