TY - CHAP A1 - Weber, Niklas A1 - Wolf, Martin R. ED - Barton, Thomas T1 - Datenerhebung für die CDG-Forschung T2 - Prozesse, Technologie, Anwendungen, Systeme und Management 2017 : angewandte Forschung in der Wirtschaftsinformatik : Tagungsband zur 30. AKWI-Jahrestagung vom 17.09.2017 bis 20.09.2017 an der Hochschule Aschaffenburg / Arbeitskreis Wirtschaftsinformatik an Fachhochschulen (AKWI) Y1 - 2017 SN - 978-3-944330-56-3 SP - 218 EP - 227 PB - mana-Buch CY - Heide ER - TY - PAT A1 - Artmann, Gerhard A1 - Linder, Peter A1 - Bayer, Robin A1 - Gossmann, Matthias T1 - Celldrum electrode arrangement for measuring mechanical stress [Patent of invention] N2 - The invention pertains to a CellDrum electrode arrangement for measuring mechanical stress, comprising a mechanical holder (1 ) and a non-conductive membrane (4), whereby the membrane (4) is at least partially fixed at its circumference to the mechanical holder (1), keeping it in place when the membrane (4) may bend due to forces acting on the membrane (4), the mechanical holder (1) and the membrane (4) forming a container, whereby the membrane (1) within the container comprises an cell- membrane compound layer or biological material (3) adhered to the deformable membrane 4 which in response to stimulation by an agent may exert mechanical stress to the membrane (4) such that the membrane bending stage changes whereby the container may be filled with an electrolyte, whereby an electric contact (2) is arranged allowing to contact said electrolyte when filled into to the container, whereby within a predefined geometry to the fixing of the membrane (4) an electrode (7) is arranged, whereby the electrode (7) is electrically insulated with respect to the electric contact (2) as well as said electrolyte, whereby mechanical stress due to an agent may be measured as a change in capacitance. Y1 - 2017 N1 - Patent auch unter EP3403090, CN109477828, US2019033245 und LU92948 veröffentlicht. PB - WIPO CY - Geneva ER - TY - CHAP A1 - Samuelsson, K. A1 - Scheer, Nico A1 - Wilson, I. A1 - Wolf, C.R. A1 - Henderson, C.J. ED - Chackalamannil, Samuel T1 - Genetically Humanized Animal Models T2 - Comprehensive Medicinal Chemistry III. 3rd Edition N2 - Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug–drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development. KW - Chimeric liver-humanized mice KW - Drug distribution KW - Drug metabolism KW - Toxicology KW - Knockout mice Y1 - 2017 SN - 978-0-12-803201-5 U6 - https://doi.org/10.1016/B978-0-12-409547-2.12376-5 SP - 130 EP - 149 PB - Elsevier CY - Saint Louis ER - TY - JOUR A1 - Wilson, Ian D. A1 - Wilson, Claire E. A1 - Scheer, Nico A1 - Dickie, A.P. A1 - Schreiter, K. A1 - Wilson, E. M. A1 - Riley, R. J. A1 - Wehr, R. A1 - Bial, J. T1 - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice JF - Biochemical pharmacology Y1 - 2017 U6 - https://doi.org/10.1016/j.bcp.2017.03.015 SN - 1873-2968 VL - Volume 135 SP - 139 EP - 150 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Small Claims Regulation T2 - European Encyclopedia of Private International Law Y1 - 2017 SN - 9781782547228 PB - Edward Elgar Publishing CY - Cheltenham, UK ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Names of individuals T2 - European Encyclopedia of Private International Law Y1 - 2017 SN - 9781782547228 PB - Edward Elgar Publishing CY - Cheltenham, UK ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin ED - Weller, Marc-Philippe ED - Kindler, Peter T1 - Art. 48 EGBGB: Wahl eines in einem anderen Mitgliedstaat der Europäischen Union erworbenen Namens, Rn. 5-8, Rn. 11-14, Rn. 45-47, Rn. 48-51 T2 - Beck‘scher Online-Großkommentar zum Bürgerlichen Recht (BeckOGK), Band: Internationales Privatrecht Y1 - 2017 PB - C.H.Beck CY - München ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Kommentierung zu §§ 1852 - 1857a T2 - Münchener Kommentar zum BGB Band 9, Familienrecht II Y1 - 2017 SN - 978-3-406-66548-6 PB - C.H.Beck CY - München ET - 7. Auflage ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Kommentierung zu §§ 1837 - 1851 T2 - Münchener Kommentar zum BGB Band 9, Familienrecht II Y1 - 2017 SN - 978-3-406-66548-6 PB - C.H.Beck CY - München ET - 7. Auflage ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin ED - Oetker, Hartmut ED - Rixecker, Roland ED - Säcker, Jürgen T1 - Kommentierung zu §§ 1802 - 1834 T2 - Münchener Kommentar zum BGB Band 9, Familienrecht II Y1 - 2017 SN - 978-3-406-66548-6 PB - C.H.Beck CY - München ET - 7. Auflage ER -