TY - JOUR A1 - Müller-Veggian, Mattea A1 - Mariscotti, M. A. J. A1 - Beuscher, H. A1 - Davidson, W. F. T1 - In-beam study of ¹⁴⁴ Gd JF - Annual report 1976 / Institut für Kernphysik Kernforschungsanlage Jülich / Ed. board: A. Fäßler ... Y1 - 1977 SP - 37 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Mariscotti, M. A. J. A1 - Beuscher, H. A1 - Davidson, W. F. T1 - In-beam study of ¹⁴⁴ Gd JF - Nuclear physics / A. 311 (1978), H. 3 Y1 - 1978 SN - 0375-9474 SP - 395 EP - 412 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Haenni, D. R. A1 - Beuscher, H. A1 - Lieder, R. M. T1 - In-beam study of ¹⁴⁵ Gd JF - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36) Y1 - 1979 SP - 27 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. T1 - In-beam γ-ray study of ¹⁸⁹,¹⁹¹,¹⁹³ Au JF - Nuclear physics / A. 327 (1979), H. 2 Y1 - 1979 SN - 0375-9474 SP - 269 EP - 287 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Kreiner, A. J. A1 - Fenzl, M. A1 - Kutschera, W. T1 - In-beam γ-spectroscopic investigation of ¹⁹⁶ Tl JF - Annual report 1977 / Institut für Kernphysik Kernforschungsanlage Jülich Y1 - 1978 N1 - Spezielle Berichte der Kernforschungsanlage Jülich ; 15 SP - 47 EP - 48 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Digel, Ilya T1 - In-situ biological decontamination of an ice melting probe Y1 - 2010 N1 - 38th COSPAR Scientific Assembly. Held 18-15 July 2010, in Bremen, Germany Abstract unter https://www.cospar-assembly.org/abstractcd/OLD/COSPAR-10/abstracts/data/pdf/abstracts/F36-0013-10.pdf ER - TY - JOUR A1 - Kuhnert, Marie-Therese A1 - Bialonski, Stephan A1 - Noenning, Nina A1 - Mai, Heinke A1 - Hinrichs, Hermann A1 - Helmstaedter, Christoph A1 - Lehnertz, Klaus T1 - Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks JF - Plos one N2 - Learning- and memory-related processes are thought to result from dynamic interactions in large-scale brain networks that include lateral and mesial structures of the temporal lobes. We investigate the impact of incidental and intentional learning of verbal episodic material on functional brain networks that we derive from scalp-EEG recorded continuously from 33 subjects during a neuropsychological test schedule. Analyzing the networks' global statistical properties we observe that intentional but not incidental learning leads to a significantly increased clustering coefficient, and the average shortest path length remains unaffected. Moreover, network modifications correlate with subsequent recall performance: the more pronounced the modifications of the clustering coefficient, the higher the recall performance. Our findings provide novel insights into the relationship between topological aspects of functional brain networks and higher cognitive functions. Y1 - 2013 U6 - http://dx.doi.org/10.1371/journal.pone.0080273 VL - 8 IS - 11 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Siqueira, Jose R. A1 - Molinnus, Denise A1 - Beging, Stefan A1 - Schöning, Michael Josef T1 - Incorporating a hybrid urease-carbon nanotubes sensitive nanofilm on capacitive field-effect sensors for urea detection JF - Analytical chemistry N2 - The ideal combination among biomolecules and nanomaterials is the key for reaching biosensing units with high sensitivity. The challenge, however, is to find out a stable and sensitive film architecture that can be incorporated on the sensor’s surface. In this paper, we report on the benefits of incorporating a layer-by-layer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors for detecting urea. Three sensor arrangements were studied in order to investigate the adequate film architecture, involving the LbL film with the enzyme urease: (i) urease immobilized directly onto a bare EIS [EIS-urease] sensor; (ii) urease atop the LbL film over the EIS [EIS-(PAMAM/CNT)-urease] sensor; and (iii) urease sandwiched between the LbL film and another CNT layer [EIS-(PAMAM/CNT)-urease-CNT]. The surface morphology of all three urea-based EIS biosensors was investigated by atomic force microscopy (AFM), while the biosensing abilities were studied by means of capacitance–voltage (C/V) and dynamic constant-capacitance (ConCap) measureaments at urea concentrations ranging from 0.1 mM to 100 mM. The EIS-urease and EIS-(PAMAM/CNT)-urease sensors showed similar sensitivity (∼18 mV/decade) and a nonregular signal behavior as the urea concentration increased. On the other hand, the EIS-(PAMAM/CNT)-urease-CNT sensor exhibited a superior output signal performance and higher sensitivity of about 33 mV/decade. The presence of the additional CNT layer was decisive to achieve a urea based EIS sensor with enhanced properties. Such sensitive architecture demonstrates that the incorporation of an adequate hybrid enzyme-nanofilm as sensing unit opens new prospects for biosensing applications using the field-effect sensor platform. Y1 - 2014 U6 - http://dx.doi.org/10.1021/ac500458s SN - 1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print) VL - 86 IS - 11 SP - 5370 EP - 5375 PB - ACS Publications CY - Columbus ER - TY - JOUR A1 - Heinzel, Alexander A1 - Schäfer, Ralf A1 - Müller, Hans-Wilhelm A1 - Schieffer, Andre A1 - Ingenhag, Ariane A1 - Eickhoff, Simon B. A1 - Northoff, Georg A1 - Franz, Matthias A1 - Hautzel, Hubertus T1 - Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study JF - Psychotherapy and Psychosomatics N2 - Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study. Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System. Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala. Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia. Y1 - 2010 U6 - http://dx.doi.org/10.1159/000320121 SN - 0033-3190 VL - 79 IS - 6 SP - 363 EP - 370 PB - Karger CY - Basel ER - TY - JOUR A1 - Heinke, Lars N. A1 - Knicker, Axel J. A1 - Albracht, Kirsten T1 - Increased shoulder muscle stretch reflex elicitability in supine subject posture JF - Isokinetics and Exercise Science N2 - BACKGROUND: Muscle stretch reflexes are widely used to examine neural muscle function. The knowledge of reflex response in muscles crossing the shoulder is limited. OBJECTIVE: To quantify reflex modulation according to various subject postures and different procedures of muscle pre-activation steering. METHODS: Thirteen healthy male participants performed two sets of external shoulder rotation stretches in various positions and with different procedures of muscle pre-activation steering on an isokinetic dynamometer over a range of two different pre-activation levels. All stretches were applied with a dynamometer acceleration of 104∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexive response was observed in all tested muscles in all experimental conditions. The reflex elicitation rate revealed a significant muscle main effect (F (5,288) = 2.358, ρ= 0.040; η2= 0.039; f= 0.637) and a significant test condition main effect (F (1,288) = 5.884, ρ= 0.016; η2= 0.020; f= 0.143). Reflex latency revealed a significant muscle pre-activation level main effect (F (1,274) = 5.008, ρ= 0.026; η2= 0.018; f= 0.469). CONCLUSION: Muscular reflexive response was more consistent in the primary internal rotators of the shoulder. Supine posture in combination with visual feedback of muscle pre-activation level enhanced the reflex elicitation rate. Y1 - 2020 U6 - http://dx.doi.org/10.3233/IES-192219 SN - 1878-5913 VL - 28 IS - 2 SP - 139 EP - 146 PB - IOS Press CY - Amsterdam ER - TY - JOUR A1 - Kraft, Bodo A1 - Heer, Thomas A1 - Retkowitz, Daniel T1 - Incremental Ontology Integration / Heer, Thomas ; Retkowitz, Daniel ; Kraft, Bodo JF - Proceedings of the 10th International Conference on Enterprise Information Systems : Barcelona, Spain, June 12 - 16, 2008 / organized by INSTICC, Institute for Systems and Technologies of Information, Control and Communication ... [Ed. by José Cordeiro ...] Y1 - 2008 N1 - International Conference on Enterprise Information Systems ; (10 : ; 2008.06.12-16 : ; Barcelona) ; ICEIS ; (10 : ; 2008.06.12-16 : ; Barcelona) SP - 13 EP - 28 PB - INSTICC CY - Setubal ER - TY - BOOK A1 - Bialonski, Stephan T1 - Inferring complex networks from time series of dynamical systems: Pitfalls, misinterpretations, and possible solutions Y1 - 2012 N1 - Bonn, Rheinische Friedrich-Wilhelms-Universität Bonn, Diss., 2012 PB - Universitäts- und Landesbibliothek Bonn CY - Bonn ER - TY - JOUR A1 - Nguyen, Nhu Huynh A1 - Duong, Minh Tuan A1 - Tran, Thanh Ngoc A1 - Pham, Phu Tinh A1 - Grottke, O. A1 - Tolba, R. A1 - Staat, Manfred T1 - Influence of a freeze–thaw cycle on the stress–stretch curves of tissues of porcine abdominal organs JF - Journal of Biomechanics N2 - The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze–thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze–thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines. KW - Autolysis KW - Decomposition KW - Freeze–thaw process KW - Spleen KW - Liver Y1 - 2012 U6 - http://dx.doi.org/10.1016/j.jbiomech.2012.07.008 SN - 1873-2380 VL - 45 IS - 14 SP - 2382 EP - 2386 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Albracht, Kirsten T1 - Influence of mechanical properties of the leg extensor muscletendon units on running economy Y1 - 2010 N1 - Cologne, German Sport Univ., Diss., 2010 PB - Deutsche Sporthochschule Köln CY - Köln ER - TY - JOUR A1 - Artmann, Gerhard A1 - Schmid-Schönbein, H. A1 - Schröder, Susanne A1 - Grebe, R. [u.a.] T1 - Influence of Moxaverine-HCL on Membrane Curvature and Microsieve Filterability of Red Cells after Exposure to Hyperosmolarity and Lactacidosis. Schmid-Schönbein, H.; Schröder, Susanne; Grebe, R.; Artmann, Gerhard Michael, Eschweiler, H; Teitel, P. JF - Arzneimittelforschung. 38 (1988), H. 5 Y1 - 1988 SN - 0004-4172 SP - 710 EP - 716 ER - TY - JOUR A1 - Duong, Minh Tuan A1 - Nguyen, Nhu Huynh A1 - Tran, Thanh Ngoc A1 - Tolba, R. H. A1 - Staat, Manfred T1 - Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen JF - International biomechanics Y1 - 2015 U6 - http://dx.doi.org/10.1080/23335432.2015.1049295 SN - 2333-5432 VL - Vol. 2 IS - Iss. 1 SP - 79 EP - 88 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Lenz, Maximilian A1 - Kahmann, Stephanie Lucina A1 - Behbahani, Mehdi A1 - Pennig, Lenhard A1 - Hackl, Michael A1 - Leschinger, Tim A1 - Müller, Lars Peter A1 - Wegmann, Kilian T1 - Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation JF - Archives of Orthopaedic and Trauma Surgery N2 - Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer’s classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education. KW - Proximal humerus fracture KW - Biomechanical simulation KW - Fracture configuration KW - Fracture simulation KW - Rotator cuff Y1 - 2022 U6 - http://dx.doi.org/10.1007/s00402-022-04471-9 SN - 1434-3916 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Bertz, Morten A1 - Schöning, Michael Josef A1 - Molinnus, Denise A1 - Homma, Takayuki T1 - Influence of temperature, light, and H₂O₂ concentration on microbial spore inactivation: in-situ Raman spectroscopy combined with optical trapping JF - Physica status solidi (a) applications and materials science N2 - To gain insight on chemical sterilization processes, the influence of temperature (up to 70 °C), intense green light, and hydrogen peroxide (H₂O₂) concentration (up to 30% in aqueous solution) on microbial spore inactivation is evaluated by in-situ Raman spectroscopy with an optical trap. Bacillus atrophaeus is utilized as a model organism. Individual spores are isolated and their chemical makeup is monitored under dynamically changing conditions (temperature, light, and H₂O₂ concentration) to mimic industrially relevant process parameters for sterilization in the field of aseptic food processing. While isolated spores in water are highly stable, even at elevated temperatures of 70 °C, exposure to H₂O₂ leads to a loss of spore integrity characterized by the release of the key spore biomarker dipicolinic acid (DPA) in a concentration-dependent manner, which indicates damage to the inner membrane of the spore. Intensive light or heat, both of which accelerate the decomposition of H₂O₂ into reactive oxygen species (ROS), drastically shorten the spore lifetime, suggesting the formation of ROS as a rate-limiting step during sterilization. It is concluded that Raman spectroscopy can deliver mechanistic insight into the mode of action of H₂O₂-based sterilization and reveal the individual contributions of different sterilization methods acting in tandem. KW - hydrogen peroxide KW - optical spore trapping KW - Raman spectroscopy KW - sterilization conditions KW - temperature Y1 - 2024 U6 - http://dx.doi.org/10.1002/pssa.202300866 SN - 1862-6319 (Online) SN - 1862-6300 (Print) IS - Early View PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Kopp, Alexander A1 - Schunck, Laura A1 - Gosau, Martin A1 - Smeets, Ralf A1 - Burg, Simon A1 - Fuest, Sandra A1 - Kröger, Nadja A1 - Zinser, Max A1 - Krohn, Sebastian A1 - Behbahani, Mehdi A1 - Köpf, Marius A1 - Lauts, Lisa A1 - Rutkowski, Rico T1 - Influence of the casting concentration on the mechanical and optical properties of Fa/CaCl2-derived silk fibroin membranes JF - International Journal of Molecular Sciences N2 - In this study, we describe the manufacturing and characterization of silk fibroin membranes derived from the silkworm Bombyx mori. To date, the dissolution process used in this study has only been researched to a limited extent, although it entails various potential advantages, such as reduced expenses and the absence of toxic chemicals in comparison to other conventional techniques. Therefore, the aim of this study was to determine the influence of different fibroin concentrations on the process output and resulting membrane properties. Casted membranes were thus characterized with regard to their mechanical, structural and optical assets via tensile testing, SEM, light microscopy and spectrophotometry. Cytotoxicity was evaluated using BrdU, XTT, and LDH assays, followed by live–dead staining. The formic acid (FA) dissolution method was proven to be suitable for the manufacturing of transparent and mechanically stable membranes. The fibroin concentration affects both thickness and transparency of the membranes. The membranes did not exhibit any signs of cytotoxicity. When compared to other current scientific and technical benchmarks, the manufactured membranes displayed promising potential for various biomedical applications. Further research is nevertheless necessary to improve reproducible manufacturing, including a more uniform thickness, less impurity and physiological pH within the membranes. Y1 - 2020 U6 - http://dx.doi.org/10.3390/ijms21186704 SN - 1422-0067 N1 - Special issue: Optimization of Biomaterials for Reconstructive and Regenerative Medicine VL - 21 IS - 18 art. no. 6704 PB - MDPI CY - Basel ER - TY - JOUR A1 - Albracht, Kirsten A1 - Arampatzis, Adamantios T1 - Influence of the mechanical properties of the muscle-tendon unit on force generation in runners with different running economy JF - Biological Cybernetics Y1 - 2006 U6 - http://dx.doi.org/10.1007/s00422-006-0070-z SN - 1432-0770 VL - 95 IS - 1 SP - 87 EP - 96 ER - TY - JOUR A1 - Stulpe, Werner A1 - Singer, Matthias T1 - Informational Incompleteness of the Observables Sx,Sy,Sz for Spin-1 Systems. Singer, Matthias; Stulpe, W. JF - Foundations of Physics. 20 (1990), H. 4 Y1 - 1990 SN - 1572-9516 SP - 471 EP - 472 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zhou-Stache, J. A1 - Buettner, R. A1 - Mittermayer, C. [u.a.] T1 - Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K. JF - Medical and Biological Engineering and Computing. 40 (2002), H. 6 Y1 - 2002 SN - 0140-0118 SP - 698 EP - 703 ER - TY - JOUR A1 - Hamad, E. M. A1 - Bilatto, S. E. R. A1 - Adly, N. Y. A1 - Correa, D. S. A1 - Wolfrum, B. A1 - Schöning, Michael Josef A1 - Offenhäusser, A. A1 - Yakushenko, A. T1 - Inkjet printing of UV-curable adhesive and dielectric inks for microfluidic devices JF - Lab on a Chip N2 - Bonding of polymer-based microfluidics to polymer substrates still poses a challenge for Lab-On-a-Chip applications. Especially, when sensing elements are incorporated, patterned deposition of adhesives with curing at ambient conditions is required. Here, we demonstrate a fabrication method for fully printed microfluidic systems with sensing elements using inkjet and stereolithographic 3D-printing. Y1 - 2016 U6 - http://dx.doi.org/10.1039/C5LC01195G SN - 1473-0189 VL - 16 IS - 1 SP - 70 EP - 74 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schubert, J A1 - Kloock, Joachim P. A1 - Zander, W. A1 - Mourzina, Y. G. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Innovative thin film techniques for microfabricating electrochemical sensors JF - Lecture Notes of the ICB Seminars Y1 - 2002 SP - 55 EP - 66 PB - MCB CY - Warsaw ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schubert, Joachim P. A1 - Kloock, Joachim P. A1 - Zander, W. A1 - Mourzina, Y. G. A1 - Legin, A. A1 - Vlasov, Y. G. A1 - Lüth, H. T1 - Innovative thin film techniques for microfabricating electrochemical sensors JF - Biocybernetics and Biomedical Engineering. 21 (2001), H. 4 Y1 - 2001 SN - 0208-5216 SP - 107 EP - 119 ER - TY - JOUR A1 - Kloock, Joachim P. A1 - Mourzina, Y.G. A1 - Ermolenko, Y. A1 - Doll, T. A1 - Schubert, J. A1 - Schöning, Michael Josef T1 - Inorganic thin-film sensor membranes with PLD-prepared chalcogenide glasses: Challenges and implementation JF - Sensors. 4 (2004), H. 10 Y1 - 2004 SN - 1424-8220 SP - 156 EP - 162 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Schroth, Peter A1 - Lüth, Hans A1 - Hummel, Hans E. A1 - Schütz, Stefan T1 - Insect chemoreceptors coupled to silicon transistors as innovative biosensors JF - Proceedings of SPIE. 4205 (2001) Y1 - 2001 SP - 152 EP - 162 ER - TY - JOUR A1 - Schütz, S. A1 - Czynski, J. A1 - Hummel, Hans E. A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Kordos, P. A1 - Lüth, H. T1 - Insect meets microelectronics: A BioFET as a first step to bioelectronic microsystems JF - Transducers '99 : proceedings of the Tenth International Conference on Solid-State Sensors and Actuators ; 7 - 10 June, 1999, Sendai, Japan / ed.: S. Middelhoek Y1 - 2000 N1 - International Conference on Solid State Sensors and Actuators <10, 1999, Sendai, Miyagi-ken> ; Transducers '99 ; (10 : ; 1999.06.07-10 : ; Sendai) SP - 1104 EP - 1107 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Schroth, P. A1 - Schöning, Michael Josef A1 - Kordos, P. A1 - Lüth, H. A1 - Schütz, S. A1 - Weißbecker, B. A1 - Hummel, Hans E. T1 - Insectbased BioFETs with improved signal characteristics JF - Biosensors & Bioelectronics. 14 (1999), H. 3 Y1 - 1999 SN - 0956-5663 SP - 303 EP - 308 ER - TY - JOUR A1 - Sponagel, Stefan A1 - Akbay, U. A1 - Becker, E. T1 - Instability of plane Couette flow of viscoelastic liquids JF - Journal of non-Newtonian fluid mechanics. 18 (1985), H. 2 Y1 - 1985 SN - 0377-0257 SP - 123 EP - 141 ER - TY - JOUR A1 - Sponagel, Stefan A1 - Akbay, U. A1 - Becker, E. A1 - Krozer, S. T1 - Instability of slow viscometric flow JF - Mechanics Research Communications. 7 (1980), H. 4 Y1 - 1980 SN - 0093-6413 SP - 199 EP - 204 ER - TY - JOUR A1 - Rolka, David A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Integration of a capacitive EIS sensor into a FIA system for pH and penicillin determination JF - Sensors. 4 (2004) Y1 - 2004 SN - 1424-8220 SP - 84 EP - 94 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Malzahn, K. A1 - Abouzar, Maryam H. A1 - Mehndiratta, P. A1 - Katz, E. A1 - Schöning, Michael Josef T1 - Integration of biomolecular logic gates with field-effect transducers JF - Electrochimica Acta. 56 (2011), H. 26 Y1 - 2011 SN - 0013-4686 SP - 9661 EP - 9665 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schäfer, Horst A1 - Mende, H. H. T1 - Interaction between laminated g.o.3% SiFe sheets due to gap-stray fields and edge peaks JF - Physica Scripta. 39 (1989), H. 3 Y1 - 1989 SN - 0031-8949 SP - 397 EP - 400 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Krämer, Melina A1 - Abouzar, Maryam H. A1 - Pita, Marcos A1 - Katz, Evgeny A1 - Schöning, Michael Josef T1 - Interfacing of biocomputing systems with silicon chips: Enzyme logic gates based on field-effect devices JF - Procedia Chemistry. 1 (2009), H. 1 Y1 - 2009 SN - 1876-6196 N1 - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 SP - 682 EP - 685 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hekmat, Khosro A1 - Salemink, B. A1 - Lauterbach, Gerhard A1 - Schwinger, R. H. G. A1 - Südkamp, M. A1 - Weber, Hans-Joachim A1 - Mehlhorn, U. T1 - Interference by cellular phones with permanent implanted pacemakers: an update JF - Europace. 6 (2004), H. 4 Y1 - 2004 SP - 363 EP - 369 ER - TY - JOUR A1 - Bialonski, Stephan A1 - Wellmer, Jörg A1 - Elger, Christian E. A1 - Lehnertz, Klaus T1 - Interictal focus localization in neocortical lesional epilepsies with synchronization cluster analysis JF - Epilepsia Y1 - 2006 SN - 0013-9580 VL - 47 SP - 36 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Lieder, R. M. A1 - Bochev, B. A1 - Didelez, J. P. T1 - Interpretation of proton spectra measured in the ²⁰⁹ Bi (g,pxn) reaction by exiton model JF - Annual report 1981 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 146) Y1 - 1982 SP - 34 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Neskakis, A. A1 - Lieder, R. M. A1 - Sletten, G. T1 - Interpretations of the side-bands in ¹⁸⁰ Os in the framework of the cranked shell model JF - Annual report 1981 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 146) Y1 - 1982 SP - 62 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Laura, C.O. A1 - Drechsler, Klaus A1 - Erdt, M. A1 - Wesarg, S. A1 - Bale, R. T1 - Intervention assessment tool for primary tumors in the liver JF - Current Directions in Biomedical Engineering N2 - After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm. Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0081 SN - 2364-5504 VL - 4 IS - 1 SP - 337 EP - 340 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Maier, Mathias A1 - Feucht, Nikolaus T1 - Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma / Lanzl, Ines M. ; Maier, Mathias ; Feucht, Nikolaus ; Lohmann, Chris P. ; Kotliar, Konstantin E. JF - American Journal of Ophthalmology . 145 (2008), H. 1 Y1 - 2008 SN - 1879-1891 SP - 185 EP - 185 PB - - ER - TY - JOUR A1 - Hackl, Michael A1 - Nacov, Julia A1 - Kammerlohr, Sandra A1 - Staat, Manfred A1 - Buess, Eduard A1 - Leschinger, Tim A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure JF - The American Journal of Sports Medicine Y1 - 2021 U6 - http://dx.doi.org/10.1177/03635465211006138 SN - 1552-3365 SN - 0363-5465 VL - 49 IS - 7 SP - 1847 EP - 1853 PB - Sage CY - London ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus A1 - Lohmann, Chris A1 - Lanzl, Ines T1 - Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply JF - Acta Ophthalmologica Y1 - 2008 SN - 1755-3768 VL - 86 IS - 6 SP - 692 EP - 693 PB - - ER - TY - JOUR A1 - Anding, Ralf A1 - Tabaza, Ruth A1 - Staat, Manfred A1 - Trenz, Eva A1 - Lohmann, Philipp A1 - Klinge, Uwe A1 - Kirschner-Hermanns, Ruth T1 - Introducing a method of in vitro testing of different anchoring systems used for female incontinence and prolapse surgery JF - BioMed research international Y1 - 2013 SN - 1110-7251 (E-Journal); 2314-6141 (E-Journal); 1110-7243 (Print); 2314-6133 (Print) VL - Vol. 2013 SP - Article ID 401417 ER - TY - JOUR A1 - Dikta, Gerhard A1 - Subramanian, Sundarraman T1 - Inverse censoring weighted median regression / Sundarraman Subramanian and Gerhard Dikta JF - Statistical Methodology. 6 (2009), H. 6 Y1 - 2009 SN - 1572-3127 SP - 594 EP - 603 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Näther, Niko A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Schöning, Michael Josef T1 - Investigation of different catalytically active and passive materials for realising a hydrogen peroxide gas sensor JF - physica status solidi (a) . 206 (2009), H. 3 Y1 - 2009 SN - 1862-6319 N1 - Special Issue: Engineering of Functional Interfaces (EnFI 08) SP - 449 EP - 454 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Khodaverdi, M. A1 - Chatziioannou, A. F. A1 - Weber, S. A1 - Ziemons, Karl A1 - Halling, H. A1 - Pietrzyk, U. T1 - Investigation of different MicroCT scanner configurations by GEANT4 simulations JF - IEEE Transactions on Nuclear Science N2 - This study has been performed to design the combination of the new ClearPET (ClearPET is a trademark of the Crystal Clear Collaboration), a small animal positron emission tomography (PET) system, with a micro-computed tomography (microCT) scanner. The properties of different microCT systems have been determined by simulations based on GEANT4. We will demonstrate the influence of the detector material and the X-ray spectrum on the obtained contrast. Four different detector materials (selenium, cadmium zinc telluride, cesium iodide and gadolinium oxysulfide) and two X-ray spectra (a molybdenum and a tungsten source) have been considered. The spectra have also been modified by aluminum filters of varying thickness. The contrast between different tissue types (water, air, brain, bone and fat) has been simulated by using a suitable phantom. The results indicate the possibility to improve the image contrast in microCT by an optimized combination of the X-ray source and detector material. Y1 - 2005 SN - 0018-9499 VL - 52 IS - 1 SP - 188 EP - 192 ER - TY - JOUR A1 - Khodaverdi, M. A1 - Chaziioannou, A. F. A1 - Weber, S. A1 - Ziemons, Karl A1 - Halling, H. A1 - Pietrzyk, U. T1 - Investigation of different microCT scanner configurations by GEANT4 simulations JF - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 4 N2 - This study has been performed to design the combination of the new ClearPET TM (ClearPET is a trademark of the Crystal Clear Collaboration), a small animal Positron Emission Tomography (PET) system, with a microComputed Tomography (microCT) scanner. The properties of different microCT systems have been determined by simulations based on GEANT4. We demonstrate the influence of the detector material and the X-ray spectrum on the obtained contrast. Four different detector materials (selenium, cadmium zinc telluride, cesium iodide and gadolinium oxysulfide) and two X-ray spectra (a molybdenum and a tungsten source) have been considered. The spectra have also been modified by aluminum filters of varying thickness. The contrast between different tissue types (water, air, brain, bone and fat) has been simulated by using a suitable phantom. The results indicate the possibility to improve the image contrast in microCT by an optimized combination of the X-ray source and detector material. Y1 - 2004 SN - 1082-3654 SP - 2989 EP - 2993 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. A1 - Mayer-Böricke, C. T1 - Investigation of high spin states and isomers in ¹³⁶,¹³⁷ Ce JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976) Y1 - 1976 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1976=6.R.11,8 SP - 911 EP - 912 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Neskakis, A. A1 - Lieder, R. M. A1 - Beuscher, H. T1 - Investigation of high-spin states in odd-odd ¹⁹⁰,¹⁹²,¹⁹⁴ Au nuclei JF - Nuclear physics / A, Nuclear and hadronic physics. 290 (1982), H. 1 Y1 - 1982 SN - 0375-9474 SP - 53 EP - 69 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. A1 - lieder, R. M. T1 - Investigation of high-spin states in ¹³⁸,¹³⁹ Nd JF - Nuclear physics / A. 344 (1980), H. 1 Y1 - 1980 SN - 0375-9474 SP - 89 EP - 108 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. T1 - Investigation of high-spin states in ¹³⁸,¹³⁹ Nd JF - Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49) Y1 - 1980 SN - 0-85498-140-3 N1 - Conference on the Structure of Medium Heavy Nuclei <6, 1979, Rodos> ; European Physical Society / Nuclear Physics Division SP - 112 PB - Inst. of Physics CY - Bristol ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. T1 - Investigation of high-spin states in ¹³⁹ Nd JF - Annual report 1979 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 72) Y1 - 1980 SP - 46 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Ismail, A.B.M. A1 - Harada, T. A1 - Yoshinobu, T. A1 - Iwasaki, H. A1 - Schöning, Michael Josef A1 - Lüth, H. T1 - Investigation of pulsed laser-deposited Al2O3 as a high pH-sensitive layer for LAPS-based biosensing applications JF - Sensors and Actuators B. 71 (2000), H. 3 Y1 - 2000 SN - 0925-4005 SP - 169 EP - 172 ER - TY - JOUR A1 - Jansen, S. V. A1 - Behbahani, Mehdi A1 - Laumen, M. A1 - Kaufmann, T. A1 - Hormes, M. A1 - Behr, M. A1 - Schmitz-Rode, T. A1 - Steinseifer, U. T1 - Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation Y1 - 2010 N1 - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Hamacher, A. A1 - Kinast, R. T1 - Investigation of the grooves on p-contacts of position-sensitive germanium detectors JF - Annual report 1993 / Forschungszentrum Jülich Institut für Kernphysik / Baur, G. (Hrsg.). - (Berichte des Forschungszentrums Jülich ; 2879) Y1 - 1994 PB - Forschungszentrum, Zentralbibliothek CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea T1 - Investigation of the preequilibrium reaction mechanism through the study of the isomer ratios ²¹¹,²¹² Po JF - Annual report 1979 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 72) Y1 - 1980 SP - 32 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Breuer, Lars A1 - Mang, Thomas A1 - Schöning, Michael Josef A1 - Thoelen, Ronald A1 - Wagner, Torsten T1 - Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography JF - Sensors and Actuators A: Physical Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.sna.2017.11.031 SN - 0924-4247 VL - 268 SP - 126 EP - 132 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Neskakis, A. A1 - Lieder, R. M. T1 - Investigation of ¹⁸¹⁻¹⁸⁴ OS and ¹⁸¹ Re; evidence for p-backbending JF - Annual report 1975 / Institut für Kernphysik Kernforschungsanlage Jülich / Ed. board: A. Fäßler ... Y1 - 1976 SP - 47 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Artmann, Gerhard A1 - Trzewik, J. A1 - Schmid-Schönbein, G. W. T1 - Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Schönbein, G. W. JF - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1 Y1 - 2000 SN - 1862-278X SP - 521 EP - 522 ER - TY - JOUR A1 - Akimbekov, N. Sh. A1 - Digel, Ilya A1 - Zhubanova, A. A. T1 - Investigation the Influence of Carbonized Material Based On Rice Husk on Viability and Migration of Fibroblasts in T3B3 Cell Culture JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 N1 - Original in russischer Sprache VL - 59 IS - 3/1 SP - 20 EP - 23 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. T1 - Investigations of high spin states in ¹³⁸,¹³⁹ Nd JF - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36) Y1 - 1979 SP - 24 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Akimbekov, N.Sh. A1 - Digel, Ilya A1 - Savitkaya, I.S. A1 - Zhubanova, A.A. A1 - Tastambek, K.T. T1 - Investigations of LPS endotoxin elimination in the flowing column conditions with the sorbent on the basis of carbonized rice husk JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 N1 - Original in russischer Sprache VL - 57 IS - 1 SP - 124 EP - 127 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Crott, M. A1 - Ronkel, F. A1 - Thust, M. A1 - Schultze, J. W. A1 - Kordos, P. A1 - Lüth, H. T1 - Investigations on porous silicon layers with regard to chemical microsensor applications JF - Third International Conference on Intelligent Materials : Lyon, 3-4-5 June 1996, Center of Congress "L'Espace Tête d'Or" / [publ. by SPIE, the International Society for Optical Engineering]. General chair/ed. by: P. F. Gobin Y1 - 1996 SN - 0819421650 N1 - International Conference on Intelligent Materials ; (3, 1996, Lyon) SP - 275 EP - 280 PB - SPIE CY - Bellingham, Wash. ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Bruns, M. A1 - Hoffmann, W. A1 - Hoffmann, B. (u.a.) T1 - Iodide ion-sensitive field-effect structures JF - Sensors and Actuators B. 15 (1993), H. 1-3 Y1 - 1993 SN - 0925-4005 SP - 192 EP - 194 ER - TY - JOUR A1 - Weckesser, Martin A1 - Grießmeier, Martin A1 - Schmidt, Daniela A1 - Sonnenberg, Frank A1 - Ziemons, Karl A1 - Kemna, Lars A1 - Holschbach, Marcus A1 - Langen, Karl-J. A1 - Müller-Gärtner, Hans-W. T1 - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent JF - European Journal of Nuclear Medicine N2 - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment. Y1 - 1998 SN - 1619-7089 VL - 25 IS - 2 SP - 150 EP - 156 ER - TY - JOUR A1 - Mourzina, Y. G. A1 - Yoshinobu, T. A1 - Schubert, J. A1 - Lüth, H. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - Ion-selective lightaddressable potentiometric sensor (LAPS) with chalcogenide thin film by pulsed laser deposition JF - Sensors and Actuators B. 80 (2001), H. 2 Y1 - 2001 SN - 0925-4005 SP - 136 EP - 140 ER - TY - CHAP A1 - Beging, Stefan A1 - Poghossian, Arshak A1 - Mlynek, D. A1 - Hataihimakul, S. A1 - Pedraza, A. A1 - Dhawan, S. A1 - Laube, N. A1 - Kleinen, L. A1 - Baldsiefen, G. A1 - Busch, H. A1 - Schöning, Michael Josef T1 - Ion-selective sensors for the determination of the risk of urinary stone formation T2 - Micro- and Nanosystems in biochemical diagnosis : Principles and applications Y1 - 2010 SP - 74 EP - 80 CY - Warsaw ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Sauke, M. A1 - Steffen, A. A1 - Marso, M. (u.a.) T1 - Ion-sensitive field-effect transistors with ultrathin Langmuir-Blodgett membranes JF - Sensors and Actuators B. 27 (1995), H. 1-3 Y1 - 1995 SN - 0925-4005 SP - 325 EP - 328 ER - TY - JOUR A1 - Leschinger, Tim A1 - Besch, Katharina A1 - Aydin, Cansu A1 - Staat, Manfred A1 - Scaal, Martin A1 - Müller, Lars Peter A1 - Wegmann, Kilian T1 - Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique JF - The Orthopaedic Journal of Sports Medicine Y1 - 2019 U6 - http://dx.doi.org/10.1177/2325967119864590 VL - 7 IS - 8 SP - 1 EP - 5 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Gono, Y. T1 - Isomeric 10⁺ states in nuclei with N=78 JF - Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl. Y1 - 1978 N1 - International Conference on Nuclear Structure <1977, Tokyo> SP - 861 PB - Physical Soc. of Japan CY - Tokyo ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Bochev, B. A1 - Kutsarova, T. T1 - Isomeric state in ¹³⁴ La JF - Annual report 1980 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 99) Y1 - 1981 SP - 47 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Bochev, B. A1 - Kutsarova, T. T1 - Isomeric state in ¹³⁶ La JF - Annual report 1980 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 99) Y1 - 1981 SP - 48 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Beuscher, H. A1 - Bochev, B. T1 - Isomeric states in ¹³⁴ Ba JF - Annual report 1979 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 72) Y1 - 1980 SP - 44 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Beuscher, H. A1 - Bochev, B. T1 - Isomeric states in ¹³⁴ Ba JF - Zeitschrift für Physik / A, Hadrons and nuclei. 298 (1980), H. 4 Y1 - 1980 SN - 1431-5831 SP - 267 EP - 271 ER - TY - JOUR A1 - Ziemons, Karl A1 - Herzog, H. A1 - Feinendegen, L. E. T1 - Iterative image reconstruction with weighted pixel contribution to projection element JF - European Journal of Nuclear Medicine Y1 - 1990 SN - 1619-7089 N1 - Abstracts of the European Association of Nuclear Medicine Congress ; V52 VL - 16 IS - 7 SP - 403 EP - 403 ER - TY - JOUR A1 - Ziemons, Karl A1 - Herzog, H. A1 - Bosetti, P. A1 - Feinendegen, L. E. T1 - Iterative image reconstruction with weighted pixel contribution to projection elements JF - European Journal of Nuclear Medicine Y1 - 1992 SN - 1619-7089 N1 - Abstracts of the European Association of Nuclear Medicine Congress 23–26 August 1992 Lisboa, Portugal ; V143-2 VL - 19 IS - 8 SP - 588 EP - 588 ER - TY - CHAP A1 - Ketelhut, Maike A1 - Göll, Fabian A1 - Braunstein, Bjoern A1 - Albracht, Kirsten A1 - Abel, Dirk T1 - Iterative learning control of an industrial robot for neuromuscular training T2 - 2019 IEEE Conference on Control Technology and Applications N2 - Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations. KW - Knee KW - Training KW - Load modeling KW - Force KW - Iterative learning control Y1 - 2019 SN - 978-1-7281-2767-5 (ePub) SN - 978-1-7281-2766-8 (USB) SN - 978-1-7281-2768-2 (PoD) U6 - http://dx.doi.org/10.1109/CCTA.2019.8920659 N1 - 2019 IEEE Conference on Control Technology and Applications (CCTA) Hong Kong, China, August 19-21, 2019 PB - IEEE CY - New York ER - TY - JOUR A1 - Ziemons, Karl T1 - Jet production and fragmentation properties in deep inelastic muon scattering JF - Zeitschrift für Physik C : Particles and Fields Y1 - 1987 SN - 0170-9739 N1 - European Muon Collaboration VL - 36 IS - 4 SP - 527 EP - 543 ER - TY - JOUR A1 - Berghoff, G. A1 - Lanske, D. A1 - Schultze, K. A1 - Ziemons, Karl T1 - Jets and QCD-effects in muon-nuclean scattering JF - Verhandlungen der Deutschen Physikalischen Gesellschaft Y1 - 1988 SN - 0420-0195 VL - 23 IS - 5 ER - TY - CHAP A1 - Braunstein, Bjoern A1 - Goldmann, Jan-Peter A1 - Albracht, Kirsten A1 - Sanno, Maximilian A1 - Willwacher, Steffen A1 - Heinrich, Kai A1 - Herrmann, Volker A1 - Brüggemann, Gert-Peter T1 - Joint specific contribution of mechanical power and work during acceleration and top speed in elite sprinters T2 - 31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013 Y1 - 2013 SN - 1999-4168 ER - TY - CHAP A1 - Goldmann, Jan-Peter A1 - Braunstein, Bjoern A1 - Heinrich, Kai A1 - Sanno, Maximilian A1 - Stäudle, Benjamin A1 - Ritzdorf, Wolfgang A1 - Brüggemann, Gert-Peter A1 - Albracht, Kirsten T1 - Joint work of the take-off leg during elite high jump T2 - Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS) Y1 - 2015 ER - TY - JOUR A1 - Mourzina, Y. A1 - Mai, T. A1 - Poghossian, Arshak A1 - Ermolenko, Y. A1 - Yoshinobu, T. A1 - Vlasov, Y. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - K+-selective field-effect sensors as transducers for bioelectronic applications JF - Electrochimica Acta. 48 (2003), H. 20-22 Y1 - 2003 SN - 0013-4686 SP - 3333 EP - 3339 ER - TY - JOUR A1 - Hillen, Walter T1 - K0 production in e+e− annihilations at 30 GeV center of mass energy. TASSO Collaboration JF - Physics Letters B. 94 (1980), H. 1 Y1 - 1980 SN - 0370-2693 SP - 91 EP - 95 ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Simsek, Beril A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study JF - Sensors N2 - Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled Néel–Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays. KW - key performance indicators KW - magnetic biosensing KW - coupled Néel–Brownian relaxation dynamics KW - frequency mixing magnetic detection KW - magnetic relaxation KW - micromagnetic simulation KW - magnetic nanoparticles Y1 - 2024 U6 - http://dx.doi.org/10.3390/s24061945 SN - 1424-8220 N1 - This article belongs to the Special Issue "Advances in Magnetic Sensors and Their Applications" VL - 24 IS - 6 PB - MDPI CY - Basel ER - TY - BOOK A1 - Laack, Walter van T1 - Key to Eternity / Walter van Laack. [Transl. by Anneliese Wolstenholme] Y1 - 2000 SN - 978-3-8311-0344-7 N1 - Schlüssel zur Ewigkeit PB - van Laack CY - Aachen ER - TY - CHAP A1 - Abel, Thomas A1 - Bonin, Dominik A1 - Albracht, Kirsten A1 - Zeller, Sebastian A1 - Brüggemann, Gert-Peter A1 - Burkett, Brendan A1 - Strüder, Heiko K. T1 - Kinematic profile of the elite handcyclist T2 - 28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 – 23, 2010 Y1 - 2017 SN - 1999-4168 SP - 140 EP - 141 ER - TY - JOUR A1 - Meyer, Carolin A1 - Gaalen, Kerstin van A1 - Leschinger, Tim A1 - Scheyerer, Max J. A1 - Neiss, Wolfram F. A1 - Staat, Manfred A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement JF - BioMed Research International Y1 - 2019 U6 - http://dx.doi.org/10.1155/2019/9232813 SP - Article ID 9232813 ER - TY - BOOK A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Label-free biosensing: advanced materials, devices and applications Y1 - 2018 SN - 978-3-319-75219-8 PB - Springer CY - Cham ER - TY - JOUR A1 - Poghossian, Arshak A1 - Ingebrandt, S. A1 - Abouzar, Maryam H. A1 - Schöning, Michael Josef T1 - Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation JF - Applied Physics A: Materials Science & Processing. 87 (2007), H. 3 Y1 - 2007 SN - 0947-8396 N1 - Special Issue “From Surface Science to Nanoscale Devices” SP - 517 EP - 524 ER - TY - JOUR A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies JF - Procedia Engineering N2 - Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride). KW - LAPS KW - lable-free detection KW - DNA hybridization KW - field-effect sensor Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.proeng.2014.11.647 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 755 EP - 758 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Schöning, Michael Josef T1 - Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer JF - Nanoscale N2 - A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent–voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout. Y1 - 2015 U6 - http://dx.doi.org/10.1039/C4NR07225A VL - 14 IS - 7 SP - 6143 EP - 6150 PB - Royal Society of Chemistry (RSC) CY - Cambridge ER - TY - JOUR A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors T1 - Markierungsfreie Detektion doppelsträngiger DNA Moleküle mit Hilfe von Polyelektrolyt-modifizierten kapazitiven Feldeffekt-Sensoren JF - tm - Technisches Messen N2 - In this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA)molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto theSiO2-chip surface.EIS sensors can be utilized as a tool to detect surface-charge changes; the electrostatic adsorption of oligonucleotides onto the polyelectrolyte layer leads to a measureable surface-potential change. Signals of 39mV have been recorded after the incubation with the oligonucleotide solution. Besides the electrochemical experiments, the successful adsorption of dsDNA onto the polyelectrolyte layer has been verified via fluorescence microscopy. The presented results demonstrate that the signal recording of EISchips, which are modified with a polyelectrolyte layer, canbe used as a favorable approach for a fast, cheap and simple detection method for dsDNA. Y1 - 2017 U6 - http://dx.doi.org/10.1515/teme-2017-0015 VL - 84 IS - 10 SP - 628 EP - 634 PB - De Gruyter CY - Oldenbourg ER - TY - JOUR A1 - Ingebrandt, S. A1 - Han, Y. A1 - Nakamura, F. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Offenhäusser, A. T1 - Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors JF - Biosensors and Bioelectronics. 22 (2007), H. 12 Y1 - 2007 SN - 0956-5663 SP - 2834 EP - 2840 ER - TY - THES A1 - Bronder, Thomas T1 - Label-free detection of tuberculosis DNA with capacitive field-effect biosensors Y1 - 2020 U6 - http://dx.doi.org/10.17192/z2021.0056 N1 - Dissertation, Universität, Marburg 2020 PB - Philipps-Universität Marburg CY - Marburg ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Scheja, Sabrina A1 - Jessing, Max A1 - Metzger-Boddien, Christoph A1 - Keusgen, Michael A1 - Poghossian, Arshak T1 - Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities JF - Proceedings N2 - Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed. Y1 - 2017 U6 - http://dx.doi.org/10.3390/proceedings1080719 SN - 2504-3900 N1 - This article belongs to the Proceedings of "Proceedings of the 5th International Symposium on Sensor Science (I3S 2017)" VL - 1 IS - 8 SP - Artikel 719 PB - MDPI CY - Basel ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Pedraza, A. M. A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles JF - Procedia Engineering. 5 (2010) Y1 - 2010 SN - 1877-7058 N1 - Proc. Eurosensors XXIV, September 5–8, 2010, Linz, Austria SP - 918 EP - 921 ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Cherstvy, Andrey G. A1 - Pedraza, Angela M. A1 - Ingebrandt, Sven A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling JF - Physica Status Solidi (a) N2 - Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface. Y1 - 2012 U6 - http://dx.doi.org/10.1002/pssa.201100710 SN - 1862-6319 VL - 209 SP - 925 EP - 934 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Bäcker, Matthias A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips JF - Physica status solidi A : Applications and materials science N2 - A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent–voltage (I–V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I–V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge. Y1 - 2014 U6 - http://dx.doi.org/10.1002/pssa.201330442 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1423 EP - 1428 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Poghossian, Arshak A1 - Bronder, Thomas A1 - Scheja, S. A1 - Wu, Chunsheng A1 - Metzger-Boddien, C. A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices T2 - Procedia Engineering N2 - A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Y1 - 2016 U6 - http://dx.doi.org/10.1016/j.proeng.2016.11.512 SN - 1877-7058 N1 - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary VL - Vol. 168 SP - 514 EP - 517 PB - Elsevier CY - Amsterdam ER -