TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Razavi, Arash A1 - Besmehn, Astrid A1 - Bijnens, Nathalie A1 - Williams, Oliver A. A1 - Haenen, Ken A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Penicillin detection with nanocrystalline-diamond field-effect sensor JF - physica status solidi (a). 205 (2008), H. 9 Y1 - 2008 SN - 1862-6319 N1 - Special Issue: Hasselt Diamond Workshop 2008 - SBDD XIII SP - 2141 EP - 2145 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Beging, Stefan A1 - Biselli, Manfred A1 - Poghossian, Arshak A1 - Wang, J. A1 - Zang, Werner A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Concept for a solid-state multi-parameter sensor system for cell-culture monitoring JF - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI Y1 - 2009 SN - 0013-4686 SP - 6107 EP - 6112 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Wenmackers, Sylvia A1 - Janssens, Stoffel D. A1 - Haenen, Ken A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films JF - Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.] Y1 - 2010 N1 - MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society SP - 1 EP - 6 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Pouyeshman, S. A1 - Schnitzler, Thomas A1 - Poghossian, Arshak A1 - Wagner, Patrick A1 - Biselli, Manfred A1 - Schöning, Michael Josef T1 - A silicon-based multi-sensor chip for monitoring of fermentation processes JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1364 EP - 1369 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Bäcker, Matthias A1 - Rakowski, D. A1 - Poghossian, Arshak A1 - Biselli, Manfred A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis JF - Journal of Biotechnology N2 - A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses. Y1 - 2013 U6 - http://dx.doi.org/10.1016/j.jbiotec.2012.03.014 SN - 0168-1656 VL - 163 IS - 4 SP - 371 EP - 376 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Gun, Jenny A1 - Gutkin, Vitaly A1 - Lev, Ovadia A1 - Boyen, Hans-Gerd A1 - Saitner, Marc A1 - Wagner, Patrick A1 - Olieslaeger, Marc D´ A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices JF - Journal of Physical Chemistry C. 115 (2011), H. 11 Y1 - 2011 SN - 1932-7455 SP - 4439 EP - 4445 PB - American Cemical Society CY - Washington, DC ER - TY - CHAP A1 - Huck, Christina A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Bifunktionaler Sensorchip für den Nachweis von Gelöstwasserstoff Y1 - 2011 SN - 978-3942710-53-4 U6 - http://dx.doi.org/10.5162/10dss2011/16.10 SP - 325 EP - 328 ER - TY - JOUR A1 - Huck, Christina A1 - Jolly, Christina A1 - Wagner, Patrick A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 1161 EP - 1164 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Bäcker, Matthias A1 - Zander, W. A1 - Schubert, J. A1 - Sukoyan, L. H. A1 - Begoyan, V. A1 - Buniatyan, V. V. A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Chemische Sensoren mit Bariumstrontiumtitanat als funktionelle Schicht zur Multiparameterdetektion T2 - 11. Dresdner Sensor-Symposium : 9.-11.12.2013 Y1 - 2013 SN - 978-3-9813484-5-3 SP - 368 EP - 372 ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Kerroumi, Iman A1 - Schusser, Sebastian A1 - Bäcker, Matthias A1 - Zander, Willi A1 - Schubert, Jürgen A1 - Buniatyan, Vahe V. A1 - Martirosyan, Norayr W. A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material JF - Electroanalysis N2 - It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate. Y1 - 2014 U6 - http://dx.doi.org/10.1002/elan.201400076 SN - 1521-4109 (E-Journal); 1040-0397 (Print) VL - 26 IS - 5 SP - 980 EP - 987 PB - Wiley-VCH CY - Weinheim ER -