TY  - JOUR
A1  - Gebhardt, Andreas
A1  - Schmidt, Frank-Michael
A1  - Hötter, Jan-Steffen
A1  - Sokalla, Wolfgang
A1  - Sokalla, Patrick
T1  - Additive Manufacturing by selective laser melting the realizer desktop machine and its application for the dental industry
JF  - Physics Procedia
Y1  - 2010
SN  - 1875-3892
N1  - Laser Assisted Net Shape Engineering 6, Proceedings of the LANE 2010, Part 2
VL  - 5
IS  - 2
SP  - 543
EP  - 549
ER  - 
TY  - JOUR
A1  - Berretz, Frank
A1  - Skorupa, Sasche
A1  - Sander, Volker
A1  - Belloum, Adam
A1  - Bubak, Marian
T1  - Actor-Driven Workflow Execution in Distributed Environments
JF  - Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.)
Y1  - 2011
SN  - 978-3-642-21877-4
N1  - Lecture Notes in Computer Science ; 6586
SP  - 287
EP  - 294
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hartung, Frank
A1  - Husoy, J. H.
T1  - Wavelet and subband coding of images - A comparative study / Hartung, F. ; Husoy, J. H.
JF  - Mathematical imaging: wavelet applications in signal and image processing : 15 - 16 July 1993, San Diego, California / sponsored and publ. by SPIE - the International Society for Optical Engineering. Andrew F. Laine, chair/ed
Y1  - 1993
SN  - 081941283X
N1  - SPIE proceedings series ; 2034 ; Society of Photo-Optical Instrumentation Engineers ; Conference ; (1993.07.15-16 : ; San Diego, Calif.)
SP  - 242
EP  - 253
PB  - SPIE
CY  - Bellingham, Wash.
ER  - 
TY  - JOUR
A1  - Weckesser, Matthias
A1  - Hufnagel, Andreas
A1  - Ziemons, Karl
A1  - Grießmeier, Martin
A1  - Sonnenberg, Frank
A1  - Hackländer, Thomas
A1  - Langen, Karl-J.
A1  - Holschbach, Markus
A1  - Elger, Christian E.
A1  - Müller-Gärtner, Hans-W.
T1  - Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy
JF  - European Journal of Nuclear Medicine
N2  - Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.
Y1  - 1997
SN  - 1619-7089
VL  - 24
IS  - 9
SP  - 1156
EP  - 1161
ER  - 
TY  - JOUR
A1  - Weckesser, Martin
A1  - Grießmeier, Martin
A1  - Schmidt, Daniela
A1  - Sonnenberg, Frank
A1  - Ziemons, Karl
A1  - Kemna, Lars
A1  - Holschbach, Marcus
A1  - Langen, Karl-J.
A1  - Müller-Gärtner, Hans-W.
T1  - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent
JF  - European Journal of Nuclear Medicine
N2  - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Y1  - 1998
SN  - 1619-7089
VL  - 25
IS  - 2
SP  - 150
EP  - 156
ER  - 
TY  - BOOK
A1  - Janser, Frank
A1  - Havermann, Marc
T1  - Inkompressible Strömungen
Y1  - 2012
SN  - 978-3-86130-446-3
N1  - Strömungslehre und Aerodynamik
PB  - Mainz
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Meliß, Michael
A1  - Späte, Frank
T1  - The solar heating system with seasonal storage at the Solar-Campus Jülich
JF  - Solar energy. Vol. 69 (2000), iss. 6
Y1  - 2000
SN  - 0038-092X
SP  - 525
EP  - 533
ER  - 
TY  - CHAP
A1  - Meliß, Michael
A1  - Späte, Frank
T1  - Solar-Campus Jülich - an interdisciplinary project
T2  - EuroSun '96 ; 10. Internationales Sonnenforum : proceedings. Bd 3
Y1  - 1996
SP  - 1281
EP  - 1285
PB  - DGS-Sonnenenergie
CY  - München
ER  - 
TY  - CHAP
A1  - Meliß, Michael
A1  - Späte, Frank
A1  - Lange, Harald
T1  - The Solar-Campus Jülich - an interdisciplinary project
T2  - Building a new century. 5th Conference on Solar Architecture and Design, Bonn, 27th of May 1998. Ed. by Eurosolar e.V. Ed. by Irm Pontenagel.
Y1  - 1999
SN  - 3-933745-03-9
SP  - 382
EP  - 387
PB  - Eurosolar-Verl.
CY  - Bonn
ER  - 
TY  - CHAP
A1  - Kroker, Jan
A1  - Hoffschmidt, Bernhard
A1  - Schwarzer, Klemens
A1  - Späte, Frank
T1  - PTC 1000 modular parabolic trough collector
T2  - Process heat collectors : state of the art within task 33/IV ; IEA SHC-Task 33 and SolarPACES-Task IV: Solar heat for industrial processes : Förderkennzeichen BMBF 0329273A / Solar Heating and Cooling Executive Committee of the International Energy Agency (IEA) ; ed. Werner Weiss
Y1  - 2008
SP  - 45
EP  - 46
PB  - AEE INTEC
CY  - Gleisdorf
ER  -