TY  - JOUR
A1  - Schlamann, Marc
A1  - Voigt, Melanie A.
A1  - Maderwald, Stefan
A1  - Bitz, Andreas
A1  - Kraff, Oliver
A1  - Ladd, Susanne C.
A1  - Ladd, Mark E.
A1  - Forsting, Michael
A1  - Wilhelm, Hans
T1  - Exposure to high-field MRI does not affect cognitive function
JF  - Journal of Magnetic Resonance Imaging
N2  - Purpose
To assess potential cognitive deficits under the influence of static magnetic fields at various field strengths some studies already exist. These studies were not focused on attention as the most vulnerable cognitive function. Additionally, mostly no magnetic resonance imaging (MRI) sequences were performed.

Materials and Methods
In all, 25 right-handed men were enrolled in this study. All subjects underwent one MRI examination of 63 minutes at 1.5 T and one at 7 T within an interval of 10 to 30 days. The order of the examinations was randomized. Subjects were referred to six standardized neuropsychological tests strictly focused on attention immediately before and after each MRI examination. Differences in neuropsychological variables between the timepoints before and after each MRI examination were assessed and P-values were calculated

Results
Only six subtests revealed significant differences between pre- and post-MRI. In these tests the subjects achieved better results in post-MRI testing than in pre-MRI testing (P = 0.013–0.032). The other tests revealed no significant results.

Conclusion
The improvement in post-MRI testing is only explicable as a result of learning effects. MRI examinations, even in ultrahigh-field scanners, do not seem to have any persisting influence on the attention networks of human cognition immediately after exposure.
Y1  - 2010
U6  - http://dx.doi.org/10.1002/jmri.22065
SN  - 1522-2586
VL  - 31
IS  - 5
SP  - 1061
EP  - 1066
PB  - Wiley-Liss
CY  - New York
ER  - 
TY  - CHAP
A1  - Konstantinidis, K.
A1  - Dachwald, Bernd
A1  - Ohndorf, A.
A1  - Dykta, P.
A1  - Voigt, K.
A1  - Förstner, R.
T1  - Enceladus explorer (ENEX): A lander mission to probe subglacial water pockets on Saturn's moon enceladus for life
T2  - 64th International Astronautical Congress 2013 (IAC 2013) : Beijing, China, 23 - 27 September 2013. (Proceedings of the International Astronautical Congress, IAC ; 2)
Y1  - 2013
SN  - 978-1-62993-909-4
SP  - 1340
EP  - 1350
PB  - Curran
CY  - Red Hook, NY
ER  - 
TY  - JOUR
A1  - Handtke, Stefan
A1  - Schroeter, Rebecca
A1  - Jürgen, Britta
A1  - Methling, Karen
A1  - Schlüter, Rabea
A1  - Albrecht, Dirk
A1  - Hijum, Sacha A. F. T. van
A1  - Bongaerts, Johannes
A1  - Maurer, Karl-Heinz
A1  - Lalk, Michael
A1  - Schweder, Thomas
A1  - Hecker, Michael
A1  - Voigt, Birgit
T1  - Bacillus pumilus reveals a remarkably high resistance to hydrogen peroxide provoked oxidative stress
JF  - PLOS one
N2  - Bacillus pumilus is characterized by a higher oxidative stress resistance than other comparable industrially relevant Bacilli such as B. subtilis or B. licheniformis. In this study the response of B. pumilus to oxidative stress was investigated during a treatment with high concentrations of hydrogen peroxide at the proteome, transcriptome and metabolome level. Genes/proteins belonging to regulons, which are known to have important functions in the oxidative stress response of other organisms, were found to be upregulated, such as the Fur, Spx, SOS or CtsR regulon. Strikingly, parts of the fundamental PerR regulon responding to peroxide stress in B. subtilis are not encoded in the B. pumilus genome. Thus, B. pumilus misses the catalase KatA, the DNA-protection protein MrgA or the alkyl hydroperoxide reductase AhpCF. Data of this study suggests that the catalase KatX2 takes over the function of the missing KatA in the oxidative stress response of B. pumilus. The genome-wide expression analysis revealed an induction of bacillithiol (Cys-GlcN-malate, BSH) relevant genes. An analysis of the intracellular metabolites detected high intracellular levels of this protective metabolite, which indicates the importance of bacillithiol in the peroxide stress resistance of B. pumilus.
Y1  - 2014
U6  - http://dx.doi.org/10.1371/journal.pone.0085625
SN  - 1932-6203
VL  - 9
IS  - 1
PB  - PLOS
CY  - San Francisco
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Bäumler, H.
A1  - Voigt, A.
A1  - Mitlöhner, R. [u.a.]
T1  - Plastic behaviour of polyelectrolyte microcapsules derived from colloid templates. Bäumler, H., Artmann, Gerhard Michael; Voigt, A., Mitlöhner, R., Neu, B., Kiesewetter, H.
JF  - Journal of Microencapsulation. 17 (2000), H. 5
Y1  - 2000
SN  - 1464-5246
SP  - 651
EP  - 655
ER  -