TY  - JOUR
A1  - Thust, M.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Naser, S.
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Crosssensitivity of a capacitive penicillin sensor combined with a diffusion barrier
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague)
SP  - 573
EP  - 576
CY  - The Hague, The Netherlands
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Platen, J.
A1  - Schöning, Michael Josef
T1  - Field-effect sensors with charged macromolecules – from micro towards nano aspects
T2  - Biochemical Sensing Utilisation of Micro-and                       Nanotechnologies, Warschau, Nov. 2005 : Lecture Notes of the                       ICB Seminar / ed.: M. Mascini, W. Torbicz
Y1  - 2006
SP  - 74
EP  - 81
PB  - Polish Academy Sciences Press
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Jablonski, Melanie
A1  - Koch, Claudia
A1  - Bronder, Thomas
A1  - Rolka, David
A1  - Wege, Christina
A1  - Schöning, Michael Josef
T1  - Field-effect biosensor using virus particles as scaffolds for enzyme immobilization
JF  - Biosensors and Bioelectronics
N2  - A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.
Y1  - 2018
U6  - https://doi.org/10.1016/j.bios.2018.03.036
SN  - 0956-5663
VL  - 110
SP  - 168
EP  - 174
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Schusser, Sebastian
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins
JF  - GIT Labor-Fachzeitschrift
Y1  - 2014
SN  - 0016-3538
IS  - 2
SP  - 28
EP  - 30
PB  - Wiley
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Schultze, J. W.
A1  - Lüth, H.
T1  - Field-effect based multifunctional hybrid sensor module for the determination of both (bio-)chemical and physical paramters
JF  - Proceedings of SPIE. 4576 (2002)
Y1  - 2002
SP  - 149
EP  - 159
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, L.
A1  - Schöning, Michael Josef
T1  - Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 649
EP  - 652
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Näther, Niko
A1  - Auger, V.
A1  - Poghossian, Arshak
A1  - Koudelka-Hep, M.
A1  - Schöning, Michael Josef
T1  - A miniaturized flow-through cell in SU-8 technique for EIS sensors
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 994
EP  - 995
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Weiland, Maryam
A1  - Schöning, Michael Josef
ED  - Lvova, Larisa
ED  - Kirsanov, Dmitry
ED  - di Natale, Corrado
ED  - Legin, Audrey
T1  - Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing
T2  - Multisensor system for chemical analysis : materials and sensors
N2  - An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.
Y1  - 2014
SN  - 978-981-4411-15-8 ; 978-981-4411-16-5
U6  - https://doi.org/10.1201/b15491-11
SP  - 333
EP  - 373
PB  - Jenny Stanford Publishing
CY  - Singapore
ET  - 1
ER  - 
TY  - JOUR
A1  - Buniatyan, V.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Aroutiounian, V. M.
A1  - Schöning, Michael Josef
T1  - BaxSr1-x TiO3/pc-Si heterojunction capacitance
JF  - Armenian journal of physics
Y1  - 2013
SN  - 1829-1171
VL  - 6
IS  - 4
SP  - 188
EP  - 197
PB  - National Academy of Sciences of Armenia
CY  - Yerevan
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Schultze, Joachim W.
T1  - Measuring seven parameters by two ISFET modules in a microcell set-up
JF  - Int. Journal of Computational Engineering Science. 4 (2003), H. 2
Y1  - 2003
SN  - 1465-8763
SP  - 257
EP  - 260
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - (Bio-­)chemical sensor array based on nanoplate SOI capacitors
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 31
EP  - 31
ER  - 
TY  - JOUR
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Reisert, Steffen
A1  - Kramer, Friederike
A1  - Begoyan, Vardges K.
A1  - Buniatyan, Vahe V.
A1  - Schöning, Michael Josef
T1  - Multi-parameter sensing using high-k oxide of barium strontium titanate
JF  - Physica status solidi (a)
N2  - High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.
Y1  - 2015
U6  - https://doi.org/10.1002/pssa.201431911
SN  - 1862-6319
VL  - 212
IS  - 6
SP  - 1259
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 47
EP  - 47
ER  - 
TY  - JOUR
A1  - Karschuck, Tobias
A1  - Schmidt, Stefan
A1  - Achtsnicht, Stefan
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Multiplexing system for automated characterization of a capacitive field-effect sensor array
JF  - Physica Status Solidi A
N2  - In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive–voltage (C–V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles.
KW  - Capacitive field-effect sensor
KW  - Gold nanoparticles
KW  - Label-free detection
KW  - Multicell
KW  - Multiplexing
Y1  - 2023
U6  - https://doi.org/10.1002/pssa.202300265
SN  - 1862-6300 (Print)
SN  - 1862-6319 (Online)
N1  - Corresponding author: Michael Josef Schöning
VL  - 220
IS  - 22
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Wendlandt, Tim
A1  - Koch, Claudia
A1  - Britz, Beate
A1  - Liedek, Anke
A1  - Schmidt, Nora
A1  - Werner, Stefan
A1  - Gleba, Yuri
A1  - Vahidpour, Farnoosh
A1  - Welden, Melanie
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System
JF  - Viruses
N2  - Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.
KW  - biosensor
KW  - horseradish peroxidase (HRP)
KW  - glucose oxidase (GOx)
KW  - enzyme cascade
KW  - turnip vein clearing virus (TVCV)
KW  - tobacco mosaic virus (TMV)
Y1  - 2023
U6  - https://doi.org/doi.org/10.3390/v15091951
SN  - 1999-4915
N1  - This article belongs to the Special Issue "Tobamoviruses 2023"
VL  - 9
IS  - 15
PB  - MDPI
CY  - Basel
ER  -