TY - JOUR A1 - Schmidt, Daniela A1 - Langen, Karl-J. A1 - Herzog, Hans A1 - Wirths, Jochen A1 - Holschbach, Markus A1 - Kiwit, Jürgen C. W. A1 - Ziemons, Karl A1 - Coenen, Heinz-H. A1 - Müller-Gärtner, Hans-W. T1 - Whole-body kinetics and dosimetry of L-3[123I]-iodo-α-methyltyrosine JF - European Journal of Nuclear Medicine Y1 - 1997 SN - 1619-7089 VL - 24 IS - 9 SP - 1162 EP - 1166 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Jannsens, R. A1 - Masri, Y. El. A1 - Michel, C. T1 - Untersuchung der Hochspinzustände in ¹⁷⁸,¹⁸⁰ Os JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976) Y1 - 1976 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1976=6.R.11,8 SP - 950 ER - TY - JOUR A1 - Streun, M. A1 - Chavan, U. A1 - Lame, H. A1 - Parl, C. A1 - Müller-Veggian, Mattea A1 - Ziemons, Karl T1 - Treating the Gain Non-Uniformity of Multi Channel PMTs by Channel-Specific Trigger Levels JF - 2006 IEEE Nuclear Science Symposium Conference Record, Vol. 2. Y1 - 2006 SN - 1082-3654 SP - 1301 EP - 1304 CY - San Diego, CA ER - TY - JOUR A1 - Bansal, N. K. A1 - Müller, C. A1 - Vieira, M. E. A1 - Faber, Christian A1 - Schwarzer, Klemens T1 - Thermal performance of a rock bed storage system JF - Proceedings : University of Stuttgart, Germany, August 28th until September 1st, 2000 / Terrastock 2000, 8th International Conference on Thermal Energy Storage. Ed.: M. Benner ... - Vol. 1 Y1 - 2000 SN - 3-9805274-1-7 N1 - Terrastock <2000, Stuttgart> ; Institut für Thermodynamik und Wärmetechnik SP - 433 EP - 439 PB - Inst. für Thermodynamik und Wärmetechnik CY - Stuttgart ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. A1 - Mayer-Böricke, C. T1 - Suche nach isomeren Zuständen in ¹³⁶ Ce JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. (VI) 10 (1975) Y1 - 1975 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1975 = 6.R.10 SP - 781 PB - Physik-Verlag CY - Weinheim ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. A1 - Mayer-Böricke, C. T1 - Study of high spin states in ¹⁹⁵,¹⁹⁷ Tl JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976) Y1 - 1976 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1976=6.R.11,8 SP - 952 ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Müller, C. A1 - Vieira da Silva, E. T1 - Solare Meerwasser-Entsalzungsanlagen mit mehrstufiger Wärmerückgewinnung / C. Müller ; K. Schwarzer ; E. Vieira da Silva ... JF - 14. Symposium Thermische Solarenergie : 12. bis 14. Mai, 2004, Kloster Banz / [Veranst.: OTTI Energie-Kolleg] Y1 - 2004 SN - 3-934681-33-6 N1 - Symposium Thermische Solarenergie ; (14, 2004, Kloster Banz) ; Energie-Kolleg ; (Regensburg) ; OTTI-Symposium Thermische Solarenergie ; Parallel als CD-ROM-Ausg. ersch. SP - 154 EP - 159 PB - Ostbayerisches Technologie-Transfer-Institut CY - Regensburg ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Müller, C. A1 - Mertes, C. T1 - Solar thermal desalination systems with multi-layer heat recovery / C. Müller ; K. Schwarzer ; C. Mertes ... JF - Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft für Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol 1 Y1 - 2004 SN - 3-9809656-1-9 N1 - EuroSun <5, 2004, Freiburg, Breisgau> ; Internationales Sonnenforum <14, 2004, Freiburg, Breisgau> ; Deutsche Gesellschaft für Sonnenenergie ; CD-ROM-Ausg.: ISBN 3-9809656-4-3 SP - 1-647-1-652 PB - PSE CY - Freiburg [Breisgau] ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Müller, C. A1 - Kleine-Hering, H. T1 - Simple solar systems for heating, hot water and cooking in high altitude regions with high solar radiation / C. Müller ; K. Schwarzer ; H. Kleine-Hering JF - Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft für Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol 1 Y1 - 2004 SN - 3-9809656-1-9 N1 - EuroSun <5, 2004, Freiburg, Breisgau> ; Internationales Sonnenforum <14, 2004, Freiburg, Breisgau> ; Deutsche Gesellschaft für Sonnenenergie ; CD-ROM-Ausg.: ISBN 3-9809656-4-3 SP - 1-653-1-658 PB - PSE CY - Freiburg [Breisgau] ER - TY - JOUR A1 - Luisier, Raphaëlle A1 - Lempiäinen, Harri A1 - Scherbichler, Nina A1 - Braeuning, Albert A1 - Geissler, Miriam A1 - Dubost, Valerie A1 - Müller, Arne A1 - Scheer, Nico A1 - Chibout, Salah-Dine A1 - Hara, Hisanori A1 - Picard, Frank A1 - Theil, Diethilde A1 - Couttet, Philippe A1 - Vitobello, Antonio A1 - Grenet, Olivier A1 - Grasl-Kraupp, Bettina A1 - Ellinger-Ziegelbauer, Heidrung A1 - Thomson, John P. A1 - Meehan, Richard R. A1 - Elcombe, Clifford R. A1 - Henderson, Colin J. A1 - Wolf, C. Roland A1 - Schwarz, Michael A1 - Moulin, Pierre A1 - Terranova, Remi A1 - Moggs, Jonathan G. T1 - Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors JF - Toxicological Sciences N2 - The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced rodent nongenotoxic hepatocarcinogenesis. Here, we have used a humanized CAR/PXR mouse model to examine potential species differences in receptor-dependent mechanisms underlying liver tissue molecular responses to PB. Early and late transcriptomic responses to sustained PB exposure were investigated in liver tissue from double knock-out CAR and PXR (CARᴷᴼ-PXRᴷᴼ), double humanized CAR and PXR (CARʰ-PXRʰ), and wild-type C57BL/6 mice. Wild-type and CARʰ-PXRʰ mouse livers exhibited temporally and quantitatively similar transcriptional responses during 91 days of PB exposure including the sustained induction of the xenobiotic response gene Cyp2b10, the Wnt signaling inhibitor Wisp1, and noncoding RNA biomarkers from the Dlk1-Dio3 locus. Transient induction of DNA replication (Hells, Mcm6, and Esco2) and mitotic genes (Ccnb2, Cdc20, and Cdk1) and the proliferation-related nuclear antigen Mki67 were observed with peak expression occurring between 1 and 7 days PB exposure. All these transcriptional responses were absent in CARᴷᴼ-PXRᴷᴼ mouse livers and largely reversible in wild-type and CARʰ-PXRʰ mouse livers following 91 days of PB exposure and a subsequent 4-week recovery period. Furthermore, PB-mediated upregulation of the noncoding RNA Meg3, which has recently been associated with cellular pluripotency, exhibited a similar dose response and perivenous hepatocyte-specific localization in both wild-type and CARʰ-PXRʰ mice. Thus, mouse livers coexpressing human CAR and PXR support both the xenobiotic metabolizing and the proliferative transcriptional responses following exposure to PB. Y1 - 2014 U6 - http://dx.doi.org/https://doi.org/10.1093/toxsci/kfu038 SN - 1094-2025 VL - 139 IS - 2 SP - 501 EP - 511 PB - Oxford University Press CY - Oxford ER -