TY  - JOUR
A1  - Dietzel, F.
A1  - Weber, Hans-Joachim
A1  - Porschen, W.
A1  - Feinendegen, L. E.
T1  - Zur Wärmeempfindlichkeit von oxischen und hypoxischen Zellen in einem Tumor
JF  - Naturwissenschaften
Y1  - 1976
U6  - http://dx.doi.org/10.1007/BF00622808
SN  - 0028-1042
VL  - 63
IS  - 12
SP  - 585
EP  - 586
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
A1  - Porschen, W.
A1  - Dietzel, F.
A1  - [u.a.], 
ED  - Streffer, Christian
T1  - In vivo analysis of the influence of combined hyperthermia and gamma irradiation on euoxic and hypoxic tumor cells
T2  - Cancer therapy by hyperthermia and radiation : [proceedings of the 2. International Symposium on Cancer Therapy by Hyperthermia and Radiation, Essen, 2.-4.6.1977]
Y1  - 1978
SN  - 0-8067-1701-7
SN  - 3-541-71701-7
SP  - 276
EP  - 277
PB  - Urban and Schwarzenberg
CY  - Baltimore ; Munich [u.a.]
ER  - 
TY  - JOUR
A1  - Porschen, W.
A1  - Gartzen, J.
A1  - Gewehr, K.
A1  - Mühlensiepen, H.
A1  - Weber, Hans-Joachim
A1  - [u.a.], 
T1  - In vivo assay of the radiation sensitivity of hypoxic tumour cells : influence of γ-rays, cyclotron neutrons, misonidazole, hyperthermia and mixed modalities
JF  - The British journal of cancer / Supplement
N2  - Tumour cell death can be evaluated in the living mouse by externally measuring the rate of loss of tumour-bound DNA tracer. By sequentially labelling the tumour-bearing animals with ¹²⁵IUdR and ¹³¹IUdR 50 h apart, the average tumour cells at the time of the second injection are labelled by ¹²⁵IUdR and the euoxic tumour cells are specifically labelled with ¹³¹IUdR. Tumour treatment at this stage of labelling permits the observation of the reaction of euoxic cells and average tumour cells and finally yields data on hypoxic cells and thus on the oxygen enhancement ratio. This information adds to results from tumour control and growth delay.

With this technique effects were analysed of 60-Co γ-rays, cyclotron neutrons (E = 6 MeV), misonidazole (500 mg/kg body wt) and hyperthermia (42°C water-bath), or combinations of these.

Misonidazole (15 min before irradiation) altered the oxygen enhancement ratio by a factor of 1·5 for γ-rays and of 1·1 for neutrons; when evaluated from tumour-growth delay and TCD-50 misonidazole gave a dose modifying factor of 1·47 for γ-rays and of 1·2-1·3 for neutrons.

Based on percentage tumour regression 100 days after treatment, the enhancement ratio from hyperthermia (after irradiation) was 2·75 for γ-rays (at 10 Gray) and 2·2 for neutrons (at 3·2 Gray). For neutrons combined with misonidazole and hyperthermia the ratio was 2·4.

These results demonstrate that effects of neutron irradiation may be modified by electron-affinic substances and/or hyperthermia.
Y1  - 1978
SN  - 0306-9443
N1  - Section 6: Sensitization and Hypoxic Cytotoxicity: Effects of Hyperthermia and High Let
IS  - 3
SP  - 194
EP  - 197
PB  - Lewis
CY  - London
ER  - 
TY  - BOOK
A1  - Weber, Hans-Joachim
T1  - In-vivo-Untersuchungen am Experimentaltumor Sarkom 180 über die Therapieeffizienz von Gammastrahlen und Neutronen in Verbindung mit Hyperthermie und Misonidazol
Y1  - 1982
N1  - Düsseldorf, Univ., Diss., 1982
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schmitt, W.
A1  - Jahn, D.
T1  - Thermische Untersuchungen beim Bohren in kortikalem Knochen unter Verwendung verschiedener Kühlsysteme / Schmitt, W. ; Weber, H. J. ; Jahn, D.
JF  - Deutsche zahnärztliche Zeitschrift : DZZ. 43 (1988), H. 7
Y1  - 1988
SN  - 0012-1029
SP  - 802
EP  - 805
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schmitt, W.
A1  - Jahn, D.
A1  - Euringer, H.
T1  - Ein Versuch zur theoretischen Temperaturermittlung im Schneidbereich bei Bohrungen in kortikalem Knochen - An Experiment to Calculate the Theoretical Temperature at the Drill - Cortical Bone Interface / Schmitt, W. ; Weber, H. J. ; Jahn, D. ; Euringer, H.
JF  - Biomedizinische Technik/Biomedical Engineering. 34 (1989), H. 3
Y1  - 1989
SN  - 0013-5585
N1  - in der Bereichsbibliothek Jülich gedruckt vorhanden
SP  - 53
EP  - 56
ER  - 
TY  - JOUR
A1  - Traud, S.
A1  - Gottschling, C.
A1  - Haas, J.
A1  - Gatzweiler, Karl-Heinz
A1  - Weber, Hans-Joachim
T1  - Internet-Server für die Kardiotechnik an der Fachhochschule Aachen/Jülich
JF  - Kardiotechnik. 4 (1996), H. 3
Y1  - 1996
SN  - 0941-2670
SP  - 82
EP  - 85
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
T1  - Applied physics of compressible and incompressible fluids
T2  - Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo
Y1  - 1998
SN  - 978-94-010-6306-7
SP  - 63
EP  - 84
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Schulte, A.
A1  - Lauterbach, Gerhard
A1  - Südkamp, Michael [u.a.]
T1  - Studienüberblick zu transienten Druckexkursionen bei Membranoxygenatoren / A. Schulte, G. Lauterbach, M. Südkamp, H.-J. Weber
JF  - Kardiotechnik. 8 (1999), H. 1
Y1  - 1999
SN  - 0941-2670
SP  - 14
EP  - 16
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
T1  - Verbundforschungsprojekt Multimediale 3D-Visualisierung der Herzmuskelerregung
JF  - Intelligente, innovative Produktentwicklung  für  die  industrielle  Praxis. Stenzel, Horst [Hrsg.]
Y1  - 2001
N1  - Forschungsverbund Multimedia an Fachhochschulen in Nordrhein-Westfalen
SP  - 99
EP  - 112
PB  - Forschungverbund Multimedia an Fachhochschulen
CY  - Köln
ER  -