TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Garbe, S.
A1  - Nour, Y.
A1  - Wolf, K.
T1  - Scattered dose determination using the semiconductor diodes for a mask based whole brain radiotherapy (WBRT) with high-energy photons
JF  - Biomedizinische Technik. 50 (2005), H. 2
Y1  - 2005
SN  - 0932-4666
SP  - 1069
EP  - 1070
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Garbe, S.
A1  - Nour, Y.
A1  - Wolf, K.
T1  - 468 Scatter dose determination at the eye lens during a mask based whole brain radiotherapy (WBRT)
JF  - Radiotherapy and Oncology
Y1  - 2005
U6  - http://dx.doi.org/10.1016/S0167-8140(05)81444-6
SN  - 0167-8140
VL  - 76
IS  - Suppl. 2
SP  - S202
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Samuelsson, K.
A1  - Scheer, Nico
A1  - Wilson, I.
A1  - Wolf, C.R.
A1  - Henderson, C.J.
ED  - Chackalamannil, Samuel
T1  - Genetically Humanized Animal Models
T2  - Comprehensive Medicinal Chemistry III. 3rd Edition
N2  - Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug–drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development.
KW  - Chimeric liver-humanized mice
KW  - Drug distribution
KW  - Drug metabolism
KW  - Toxicology
KW  - Knockout mice
Y1  - 2017
SN  - 978-0-12-803201-5
U6  - http://dx.doi.org/10.1016/B978-0-12-409547-2.12376-5
SP  - 130
EP  - 149
PB  - Elsevier
CY  - Saint Louis
ER  -