TY  - JOUR
A1  - Jansen, S. V.
A1  - Behbahani, Mehdi
A1  - Laumen, M.
A1  - Kaufmann, T.
A1  - Hormes, M.
A1  - Behr, M.
A1  - Schmitz-Rode, T.
A1  - Steinseifer, U.
T1  - Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation
Y1  - 2010
N1  - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010
ER  - 
TY  - JOUR
A1  - Schmitz, Günter
A1  - Altherr, M.
A1  - Hofmann, O.
A1  - Pischinger, M. (u.a.)
T1  - Anwendung moderner Simulationstools für die Entwicklung eines elektromagnetischen Ventilaktuators
JF  - TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Aachener Workshop TransMechatronik 26. Mai 1998, Technologiezentrum am Europaplatz
Y1  - 1998
SN  - 3-931466-37-X
SP  - 55
EP  - 74
PB  - Heinz-Nixdorf-Inst, Univ.-GH Paderborn
CY  - Paderborn
ER  - 
TY  - JOUR
A1  - Mang, Thomas
A1  - Hodenius, M. A. J.
A1  - Schmitz-Rode, T.
A1  - Baumann, M.
T1  - Absorption of 10-hydroxycamptothecin into the coat of magnetoliposomes / Hodenius, M. A. J. ; Schmitz-Rode, T. ; Baumann, M. ; Ivoanova, G. ; Wong, J. E. ; Mang, T. ; Haulena, F. ; Soenen, S. J. H. ; De Cuyper, M.
JF  - Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3
Y1  - 2009
SN  - 0927-7757
N1  - Colloid and Surface Science for Nanotechnology
SP  - 20
EP  - 23
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Gall, J.
A1  - Abel, D.
A1  - Ahlbrink, N.
A1  - Andersson, J.
A1  - Diehl, M.
A1  - Pitz-Paal, R.
A1  - Schmitz, M.
A1  - Teixeira Boura, Cristiano José
T1  - Optimized control of hot-gas cycle for solar thermal power plants
T2  - Proceedings of the 7th International Modelica Conference : Como, Italy, 20-22 September 2009 / Francesco Casella, ed.
Y1  - 2009
SN  - 978-91-7393-513-5
SP  - 490
EP  - 495
PB  - The Modelica Association
ER  - 
TY  - CHAP
A1  - Gall, J.
A1  - Abel, Dirk
A1  - Ahlbrink, N.
A1  - Pitz-Paal, R.
A1  - Andersson, J.
A1  - Diehl, M.
A1  - Teixeira Boura, Cristiano José
A1  - Schmitz, M.
A1  - Hoffschmidt, Bernhard
T1  - Simulation and control of solar thermal power plants
T2  - International Conference on Renewable Energies and Power Quality : ICREPQ '10 : Granada 23rd - 25th March 2010
Y1  - 2010
SP  - 1
EP  - 5
ER  - 
TY  - JOUR
A1  - Röth, A.
A1  - Slabu, I.
A1  - Kolvenbach, K.
A1  - Engelmann, Ulrich M.
A1  - Baumann, M.
A1  - Schmitz-Rode, T.
A1  - Trahms, L.
A1  - Neumann, U.
T1  - Aufnahmekinetik von magnetischen Nanopartikeln zur Tumortherapie in humanen Pankreaskarzinomzelllinien
JF  - Zeitschrift für Gastroenterologie
Y1  - 2015
U6  - http://dx.doi.org/10.1055/s-0035-1559529
SN  - 1439-7803
VL  - 53
IS  - 8
SP  - KC139
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Röth, A.A.
A1  - Slabu, I.
A1  - Engelmann, Ulrich M.
A1  - Baumann, M.
A1  - Schmitz-Rode, T.
A1  - Neumann, U. P.
T1  - Targeting von gastroenterologischen Tumoren mittels magnetischer Nanopartikel zur hyperthermischen Therapie
JF  - Zeitschrift für Gastroenterologie
Y1  - 2017
U6  - http://dx.doi.org/10.1055/s-0037-1605124
VL  - 55
IS  - 8
SP  - KV-384
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Slabu, Ioana
A1  - Roeth, Anjali A.
A1  - Engelmann, Ulrich M.
A1  - Wiekhorst, Frank
A1  - Buhl, Eva M.
A1  - Neumann, Ulf P.
A1  - Schmitz-Rode, Thomas
T1  - Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro
JF  - Nanotechnology
Y1  - 2019
U6  - http://dx.doi.org/10.1088/1361-6528/ab033e
SN  - 1361-6528
VL  - 30
IS  - 18
SP  - 184004
ER  - 
TY  - JOUR
A1  - Schmitz, Günter
A1  - Pischinger, M.
T1  - Mechatronische Simulation eines EMV- Aktuators
JF  - TransMechatronik : Entwicklung und Transfer von Entwicklungssystemen der Mechatronik / Paderborner Workshop TransMechatronik, 24. Juni 1997, Heinz-Nixdorf-MuseumsForum. [Hrsg. Jürgen Gausemeier]
Y1  - 1997
SN  - 3-931466-22-1
N1  - HNI-Verlagsschriftenreihe ; 23
SP  - 69
EP  - 83
PB  - Heinz-Nixdorf-Inst., Univ.-GH Paderborn
CY  - Paderborn
ER  - 
TY  - JOUR
A1  - Schmitz, Günter
A1  - Bartz, R.
A1  - Hilger, U.
A1  - Siedentop, M.
T1  - Intelligent Alcohol Fuel Sensor
Y1  - 1990
N1  - SAE- Paper-No.: 900231, SAE International Congress and Exposition, Detroit, Feb. 26 - March 2, 1990
ER  - 
TY  - JOUR
A1  - Schmitz, Günter
A1  - Roetert, J.
A1  - Pischinger, M.
T1  - A Fast Intelligent VMEbus System for Combustion Analysis in Engines
JF  - 19th [nineteenth] International Symposium on Automotive Technology & [and] Automation : with particular reference to cell control and quality management systems for the manufacturing industries; Monte Carlo, 24. - 28. October 1988.
Y1  - 1988
SN  - 0947719229
SP  - 381
EP  - 391
PB  - Automotive Automation Ltd
CY  - Croydon
ER  - 
TY  - JOUR
A1  - Taylor, J. G.
A1  - Schmitz, N.
A1  - Ziemons, Karl
A1  - Grosse-Ruyken, M.-L.
A1  - Gruber, O.
A1  - Müller-Gärtner, H.-W.
A1  - Shah, N. J.
T1  - The network of brain areas involved in the motion aftereffect
JF  - Neuroimage
N2  - A network of brain areas is expected to be involved in supporting the motion aftereffect. The most active components of this network were determined by means of an fMRI study of nine subjects exposed to a visual stimulus of moving bars producing the effect. Across the subjects, common areas were identified during various stages of the effect, as well as networks of areas specific to a single stage. In addition to the well-known motion-sensitive area MT the prefrontal brain areas BA44 and 47 and the cingulate gyrus, as well as posterior sites such as BA37 and BA40, were important components during the period of the motion aftereffect experience. They appear to be involved in control circuitry for selecting which of a number of processing styles is appropriate. The experimental fMRI results of the activation levels and their time courses for the various areas are explored. Correlation analysis shows that there are effectively two separate and weakly coupled networks involved in the total process. Implications of the results for awareness of the effect itself are briefly considered in the final discussion.
Y1  - 2000
SN  - 1053-8119
VL  - 11
IS  - 4
SP  - 257
EP  - 270
ER  - 
TY  - CHAP
A1  - Ziolko, C.
A1  - Schmitz, M.
A1  - Sattler, Johannes, Christoph
A1  - Khedim, Ahmed
A1  - Hoffschmidt, Bernhard
T1  - AlSol - the open volumetric receiver technology moves to Africa
T2  - SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France
Y1  - 2010
SP  - 93
EP  - 94
PB  - Soc. OSC
CY  - Saint Maur
ER  - 
TY  - CHAP
A1  - Alexopoulos, Spiros
A1  - Hoffschmidt, Bernhard
A1  - Rau, Christoph
A1  - Schmitz, M.
A1  - Schwarzbözl, P.
A1  - Pomp, Stefan
T1  - Simulation results for a hybridized operation of a gas turbine or a burner for a small solar tower power plant
T2  - SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France
Y1  - 2010
SP  - 82
EP  - 83
PB  - Soc. OSC
CY  - Saint Maur
ER  - 
TY  - JOUR
A1  - Schmitz, M.
A1  - Hirsch, E.
A1  - Bongaerts, Johannes
A1  - Takors, Ralf
T1  - Pulse experiments as a prerequisite for the quantification of in vivo enzyme kinetics in aromatic amino acid pathway of Eschericia coli
JF  - Biotechnology progress
Y1  - 2002
SN  - 1520-6033 (E-Journal); 8756-7938 (Print)
VL  - Vol. 18
IS  - Iss. 5
SP  - 935
EP  - 941
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Roeth, Anjali A.J.
A1  - Eberbeck, Dietmar
A1  - Buhl, Eva Miriam
A1  - Neumann, Ulf Peter
A1  - Schmitz-Rode, Thomas
A1  - Slabu, Ioana
T1  - Combining Bulk Temperature and Nanoheating Enables Advanced Magnetic Fluid Hyperthermia Efficacy on Pancreatic Tumor Cells
JF  - Scientific Reports
N2  - Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95% was achieved by depositing an intracellular total thermal energy with about 50% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65% after MNP were internalized inside cells.
Y1  - 2018
U6  - http://dx.doi.org/10.1038/s41598-018-31553-9
SN  - 2045-2322
VL  - 8
IS  - 1
SP  - Article number 13210
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Buhl, Eva Miriam
A1  - Draack, Sebastian
A1  - Viereck, Thilo
A1  - Frank, 
A1  - Schmitz-Rode, Thomas
A1  - Slabu, Ioana
T1  - Magnetic relaxation of agglomerated and immobilized iron oxide nanoparticles for hyperthermia and imaging applications
JF  - IEEE Magnetic Letters
N2  - Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23% for agglomerated MNP in suspension and a decrease by up to 28% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.
Y1  - 2018
U6  - http://dx.doi.org/10.1109/LMAG.2018.2879034
SN  - 1949-307X
VL  - 9
IS  - Article number 8519617
PB  - IEEE
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Buhl, Eva Miriam
A1  - Baumann, Martin
A1  - Schmitz-Rode, Thomas
A1  - Slabu, Ioana
T1  - Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia
JF  - Current Directions in Biomedical Engineering
Y1  - 2017
U6  - http://dx.doi.org/10.1515/cdbme-2017-0096
SN  - 2364-5504
VL  - 3
IS  - 2
SP  - 457
EP  - 460
PB  - De Gruyter
CY  - Berlin
ER  -