TY - JOUR A1 - Wagner, Torsten A1 - Maris, Rob J. A1 - Ackermann, Hans-Josef A1 - Otto, Ralph A1 - Beging, Stefan A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations JF - Sensors and Actuators B: Chemical . 127 (2007), H. 1 Y1 - 2007 SN - 0925-4005 SP - 217 EP - 223 ER - TY - JOUR A1 - Gasparyan, F. V. A1 - Poghossian, Arshak A1 - Vitusevich, S. A. A1 - Petrychuk, M. V. A1 - Sydoruk, V. A. A1 - Surmalyan, A. V. A1 - Siqueira, J. R. A1 - Oliveira, O. N. A1 - Offenhäusser, A. A1 - Schöning, Michael Josef T1 - Low Frequency Noise In Electrolyte-Gate Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers JF - Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso Y1 - 2009 SN - 9780735406650 N1 - AIP conference proceedings ; 1129 ; International Conference on Noise and Fluctuations ; (20, 2009, Pisa) SP - 133 EP - 136 PB - American Inst. of Physics CY - Melville, NY ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schultze, J. W. A1 - Schöning, Michael Josef T1 - Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids JF - Electrochimica Acta. 48 (2003), H. 20-22 Y1 - 2003 SP - 3289 EP - 3297 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Platen, J. A1 - Schöning, Michael Josef T1 - Towards self-aligned nanostructures by means of layerexpansion technique JF - Electrochimica Acta. 51 (2005), H. 5 Y1 - 2005 SN - 0013-4686 SP - 838 EP - 843 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Lüth, H. A1 - Schultze, J. W. A1 - Schöning, Michael Josef T1 - (Bio-)chemical and physical microsensor array using an identical transducer principle JF - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz Y1 - 2001 SN - 0-08-044014-2 SP - 243 EP - 249 PB - Elsevier [u.a.] CY - Amsterdam [u.a.] ER - TY - CHAP A1 - Näther, Niko A1 - Poghossian, Arshak A1 - Platen, J. A1 - Yoshinobu, T. A1 - Koudelka-Hep, M. A1 - Schöning, Michael Josef T1 - Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle T2 - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Y1 - 2006 SP - 172 EP - 181 CY - Warsaw ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Poghossian, Arshak A1 - Schultze, J. W. A1 - Lüth, H. T1 - Field-effect based multifunctional hybrid sensor module for the determination of both (bio-)chemical and physical paramters JF - Proceedings of SPIE. 4576 (2002) Y1 - 2002 SP - 149 EP - 159 ER - TY - JOUR A1 - Murib, M. S. A1 - Grinsven, B. van A1 - Grieten, L. A1 - Janssens, S. D. A1 - Vermeeren, V. A1 - Eersels, K. A1 - Broeders, J. A1 - Ameloot, Marcel A1 - Michiels, L. A1 - Ceuninck, W. De A1 - Haenen, K. A1 - Schöning, Michael Josef A1 - Wagner, Patrick T1 - Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates JF - Physica Status Solidi (A). Vol. 210 (2013), iss. 5 Y1 - 2013 SN - 0031-8965 SP - 911 EP - 917 PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Murib, M. S. A1 - Yeap, W. S. A1 - Eurlings, Y. A1 - Grinsven, B. van A1 - Boyen, H.-G. A1 - Conings, B. A1 - Michiels, L. A1 - Ameloot, Marcel A1 - Carleer, R. A1 - Warmer, J. A1 - Kaul, P. A1 - Haenen, K. A1 - Schöning, Michael Josef A1 - Ceuninck, W. de A1 - Wagner, P. T1 - Heat-transfer based characterization of DNA on synthetic sapphire chips JF - Sensors and Actuators B: Chemical N2 - In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material. Y1 - 2016 U6 - https://doi.org/10.1016/j.snb.2016.02.027 SN - 0925-4005 VL - 230 IS - 230 SP - 260 EP - 271 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Molinnus, Denise A1 - Hardt, G. A1 - Käver, L. A1 - Willenberg, H.S. A1 - Kröger, J.-C. A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling JF - Sensor and Actuators B: Chemical N2 - A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2018.05.136 SN - 0925-4005 VL - 272 SP - 21 EP - 27 PB - Elsevier CY - Amsterdam ER -