TY  - CHAP
A1  - Frotscher, Ralf
A1  - Koch, Jan-Peter
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
ED  - Onate, E.
T1  - Evaluation of a computational model for drug action on cardiac tissue
T2  - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona
Y1  - 2014
SP  - 1
EP  - 12
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Sora, M.-C.
A1  - Staat, Manfred
ED  - Onate, E.
T1  - A 3D finite element model of the female pelvic floor for the reconstruction of urinary incontinence
T2  - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona
Y1  - 2014
SP  - 1
EP  - 12
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Staat, Manfred
ED  - Nithiarasu, Perumal
T1  - Homogenization of a cardiac tissue construct
T2  - CMBE15 : 4th International Conference on Computational & Mathematical Biomedical Engineering ; 29th June - 1st July 2015 ; École Normale Supérieure de Cachan ; Cachan (Paris), France
Y1  - 2015
SN  - 2227-9385
N1  - Konferenzband unter:
http://www.compbiomed.net/getfile.php?type=12/site_documents&id=Proceedings_2227-9385_compressed.pdf
SP  - 645
EP  - 648
PB  - CMBE
CY  - [s.l.]
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Duong, Minh Tuan
A1  - Staat, Manfred
T1  - Simulating beating cardiomyocytes with electromechanical coupling
T2  - II. International Conference on Biomedical Technology : 28-30 October 2015 Hannover, Germany / T. Lenarz, P. Wriggers (Eds.)
Y1  - 2015
SP  - 1
EP  - 2
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Jung, Alexander
A1  - Frotscher, Ralf
A1  - Staat, Manfred
ED  - Papadrakakis, M.
T1  - A 3D electromechanical FEM-based model for cardiac tissue
T2  - ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5–10 June 2016
Y1  - 2016
N1  - revised after the conference
P11367
ER  - 
TY  - CHAP
A1  - Jung, Alexander
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Electromechanical model of hiPSC-derived ventricular cardiomyocytes cocultured with fibroblasts
T2  - 6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK
N2  - The CellDrum provides an experimental setup to study the mechanical effects of fibroblasts co-cultured with hiPSC-derived ventricular cardiomyocytes. Multi-scale computational models based on the Finite Element Method are developed. Coupled electrical cardiomyocyte-fibroblast models (cell level) are embedded into reaction-diffusion equations (tissue level) which compute the propagation of the action potential in the cardiac tissue. Electromechanical coupling is realised by an excitation-contraction model (cell level) and the active stress arising during contraction is added to the passive stress in the force balance, which determines the tissue displacement (tissue level). Tissue parameters in the model can be identified experimentally to the specific sample.
Y1  - 2018
ER  -