TY  - JOUR
A1  - Becker, Meike
A1  - Frauenrath, Tobias
A1  - Hezel, Fabian
A1  - Krombach, Gabriele A.
A1  - Kremer, Ute
A1  - Koppers, Benedikt
A1  - Butenweg, Christoph
A1  - Goemmel, Andreas
A1  - Utting, Jane F.
A1  - Schulz-Menger, Jeanette
A1  - Niendorf, Thoralf
T1  - Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T
JF  - European Radiology
N2  - Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT’s performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)%). Conclusions: ACT’s intrinsic insensitivity to interference from electromagnetic fields renders
KW  - Magnetic resonance imaging (MRI)
KW  - MR-stethoscope
KW  - Magnetic field strength
KW  - Left ventriular function
KW  - Cardiovascular MRI
Y1  - 2010
U6  - https://doi.org/10.1007/s00330-009-1676-z
SN  - 1432-1084 (Onlineausgabe)
SN  - 0938-7994 (Druckausgabe)
VL  - 20
SP  - 1344
EP  - 1355
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Heinrichs, Uwe
A1  - Utting, Jane F.
A1  - Frauenrath, Tobias
A1  - Hezel, Fabian
A1  - Krombach, Gabriele A.
A1  - Hodenius, Michael A. J.
A1  - Kozerke, Sebastian
A1  - Niendorf, Thoralf
T1  - Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T
JF  - Magnetic Resonance in Medicine
N2  - This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T₂ mapping of the heart. First, T₂ maps are presented for oil phantoms without and with respiratory motion emulation (T₂ = (22.1 ± 1.7) ms at 1.5 T and T₂ = (22.65 ± 0.89) ms at 3.0 T). T₂ relaxometry of a ferrofluid revealed relaxivities of R2 = (477.9 ± 17) mM⁻¹s⁻¹ and R2 = (449.6 ± 13) mM⁻¹s⁻¹ for UFLARE and multiecho gradient-echo imaging at 1.5 T. For inferoseptal myocardial regions mean T₂ values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T₂-values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T₂-mapping are considered.
Y1  - 2009
U6  - https://doi.org/10.1002/mrm.22054
SN  - 1522-2594
VL  - 62
IS  - 3
SP  - 822
EP  - 828
PB  - Wiley-Liss
CY  - New York
ER  -