TY  - JOUR
A1  - Kühn, Raoul-Roman
A1  - Haugner, Werner
A1  - Staat, Manfred
A1  - Sponagel, Stefan
T1  - A Two Phase Mixture Model based on Bone Observation
N2  - An optimization method is developed to describe the mechanical behaviour of the human cancellous bone. The method is based on a mixture theory. A careful observation of the behaviour of the bone material leads to the hypothesis that the bone density is controlled by the principal stress trajectories (Wolff’s law). The basic idea of the developed method is the coupling of a scalar value via an eigenvalue problem to the principal stress trajectories. On the one hand this theory will permit a prediction of the reaction of the biological bone structure after the implantation of a prosthesis, on the other hand it may be useful in engineering optimization problems. An analytical example shows its efficiency.
KW  - Knochen
KW  - Knochenbildung
KW  - Knochenchirugie
KW  - Strukturanalyse
KW  - Schwammknochen
KW  - Knochendichte
KW  - Wolffsches Gesetz
KW  - bone structure
KW  - bone density
KW  - Wolff's Law
KW  - cancellous bone
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Beging, Stefan
A1  - Biselli, Manfred
A1  - Poghossian, Arshak
A1  - Wang, J.
A1  - Zang, Werner
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Concept for a solid-state multi-parameter sensor system for cell-culture monitoring
JF  - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI
Y1  - 2009
SN  - 0013-4686
SP  - 6107
EP  - 6112
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Beging, Stefan
A1  - Rotter, L.
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Zang, Werner
A1  - Schöning, Michael Josef
T1  - Online-Messsysteme für die automatisierte Charakterisierung von feldeffektbasierten Biosensoren
JF  - 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)
Y1  - 2007
SN  - 978-3-940046-45-1
N1  - Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29
SP  - 257
EP  - 260
PB  - TUDpress, Verl. der Wissenschaften
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Wendlandt, Tim
A1  - Koch, Claudia
A1  - Britz, Beate
A1  - Liedek, Anke
A1  - Schmidt, Nora
A1  - Werner, Stefan
A1  - Gleba, Yuri
A1  - Vahidpour, Farnoosh
A1  - Welden, Melanie
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System
JF  - Viruses
N2  - Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.
KW  - biosensor
KW  - horseradish peroxidase (HRP)
KW  - glucose oxidase (GOx)
KW  - enzyme cascade
KW  - turnip vein clearing virus (TVCV)
KW  - tobacco mosaic virus (TMV)
Y1  - 2023
U6  - https://doi.org/doi.org/10.3390/v15091951
SN  - 1999-4915
N1  - This article belongs to the Special Issue "Tobamoviruses 2023"
VL  - 9
IS  - 15
PB  - MDPI
CY  - Basel
ER  - 
TY  - CHAP
A1  - Hirt, Gerhard
A1  - Bleck, Wolfgang
A1  - Bobzin, Kirsten
A1  - Schleser, Markus
A1  - Brecher, Christian
A1  - Bührig-Polazcek, Andreas
A1  - Haberstroh, Edmund
A1  - Klocke, Fritz
A1  - Loosen, Peter
A1  - Michaeli, Walter
A1  - Poprawe, Reinhart
A1  - Reisgen, Uwe
A1  - Arntz, Kristian
A1  - Bagcivan, Nazlim
A1  - Bambach, Markus
A1  - Bäumler, Stephan
A1  - Beckemper, Stefan
A1  - Bergweiler, Georg
A1  - Breitbach, Tobias
A1  - Buchholz, Steffen
A1  - Bültmann, Jan
A1  - Diettrich, Jörg
A1  - Do-Khac, Dennis
A1  - Eilbracht, Stephan
A1  - Emonts, Michael
A1  - Flock, Dustin
A1  - Gerhardt, Kai
A1  - Gillner, Arnold
A1  - Göttmann, Alexander
A1  - Grönlund, Oliver
A1  - Hartmann, Claudia
A1  - Heinen, Daniel
A1  - Herfs, Werner
A1  - Hermani, Jan-Patrick
A1  - Holtkamp, Jens
A1  - Todor, Ivanov
A1  - Jakob, Matthias
A1  - Janssen, Andreas
A1  - Karlberger, Andreas
A1  - Klaiber, Fritz
A1  - Kutschmann, Pia
A1  - Neuß, Andreas
A1  - Prahl, Ulrich
A1  - Roderburg, Andreas
A1  - Rosen, Chris-Jörg
A1  - Rösner, Andreas
A1  - Saeed-Akbari, Alireza
A1  - Scharf, Micha
A1  - Scheik, Sven
A1  - Schleser, Markus
A1  - Schöngart, Maximilian
A1  - Stein, Lars
A1  - Steiners, Marius
A1  - Stollenwerk, Jochen
A1  - Araghi, Babak Taleb
A1  - Theiß, Sebastian
A1  - Wunderle, Johannes
T1  - Hybride Produktionssysteme
T2  - Integrative Produktionstechnik für Hochlohnländer / hrsg. von Christian Brecher
N2  - Während die virtuelle Produktentstehungskette große Gestaltungsfreiräume bietet, ist die reale Produktentstehungskette durch wesentlich mehr Randbedingungen gekennzeichnet, die nicht oder nur ansatzweise beeinflussbar sind. Die Realisierung des aus logistischer Sicht optimalen One-Piece-Flow bei gleichzeitiger Steigerung von Flexibilität und Produktivität sowie des Verschiebens der Grenze des technologisch Machbaren müssen in zukünftigen Forschungsansätzen gleichermaßen betrachtet werden. Die Grenzverschiebung auf Basis der Integration von Technologien ist dabei ein viel versprechender Ansatz, der es in vielen Fällen ermöglicht, in allen genannten Zielrichtungen gleichermaßen Potentiale zu erschließen.
Y1  - 2011
SN  - 978-3-642-20692-4 (Print) ; 978-3-642-20693-1 (E-Book)
U6  - https://doi.org/10.1007/978-3-642-20693-1_5
SP  - 465
EP  - 745
PB  - Springer
CY  - Berlin [u.a.]
ER  -