TY - JOUR A1 - Öhlschläger, Peter A1 - Quetting, Michael A1 - Alvarez, Gerardo A1 - Dürst, Matthias A1 - Gissmann, Lutz A1 - Kaufmann, Andreas M. T1 - Enhancement of immunogenicity of a therapeutic cervical cancer DNA-based vaccine by co-application of sequence-optimized genetic adjuvants JF - International Journal of Cancer Y1 - 2009 SN - 1097-0215 VL - 125 IS - 1 SP - 189 EP - 198 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schnitzler, Thomas T1 - Cultivation of hybridoma cell line CF-10H5 (DSMZ ACC477) JF - Application notes / Sartorius stedim biotech Y1 - 2009 SP - 1 EP - 4 ER - TY - JOUR A1 - Schnitzler, Thomas T1 - Kultivierung der Hybridomazelllinie CF-10H5 (DSMZ ACC477) JF - Application notes / Sartorius stedim biotech Y1 - 2009 PB - Sartorius Stedim Biotec CY - Aubagne ER - TY - JOUR A1 - Scheele, S. A1 - Bongaerts, Johannes A1 - Maurer, K.-H. A1 - Freudl, R. T1 - Sekretion einer Kofaktor-haltigen Oxidase durch Corynebacterium glutamicum JF - Chemie - Ingenieur - Technik (CIT) Y1 - 2009 SN - 1522-2640 (E-Journal); 0009-286X (Print) VL - Vol. 81 IS - Iss. 8 SP - 1309 ER - TY - PAT A1 - Bessler, Cornelius A1 - Evers, Stefan A1 - Maurer, Karl-Heinz A1 - Merkel, Marion A1 - Siegert, Petra A1 - Weber, Angrit A1 - Wieland, Susanne T1 - Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen [Offenlegungsschrift] T1 - Improved-performance proteases and detergents and cleaning agents comprising said proteases [Internationale Patentanmeldung] Y1 - 2009 SP - 1 EP - 41 PB - Deutsches Patent- und Markenamt / WIPO CY - München / Genf ER - TY - PAT A1 - Bessler, Cornelius A1 - Maurer, Karl-Heinz A1 - Merkel, Marion A1 - Siegert, Petra A1 - Wieland, Susanne T1 - Subtilisin from Bacillus Pumilus and detergent and cleaning agents containing said novel subtilisin [US Patentanmeldung / Internationale Patentanmeldung] Y1 - 2009 SP - 1 EP - 39 PB - USPTO; WIPO CY - Washington; Genf ER - TY - PAT A1 - Siegert, Petra A1 - Merkel, Marion A1 - Kluin, Cornelia A1 - O'Connell, Timothy A1 - Maurer, Karl-Heinz T1 - Wasch- und Reinigungsmittel enthaltend Proteasen aus Xanthomonas [Offenlegungsschrift] T1 - Detergents and cleaners comprising proteases from xanthomonas [Internationale Patentanmeldung] Y1 - 2008 SP - 1 EP - 15 PB - Deutsches Patent- und Markenamt / WIPO CY - München / Genf ER - TY - PAT A1 - Berg, Gabriele A1 - Bessler, Cornelius A1 - Gerlach, Jochen A1 - Gübitz, Georg A1 - Heumann, Sonja A1 - Karl, Wolfgang A1 - Maurer, Karl-Heinz A1 - Remler, Peter A1 - Ribitsch, Doris A1 - Schwab, Helmut A1 - Siegert, Petra A1 - Wieland, Susanne T1 - Mittel enthaltend Proteasen aus Stenotrophomonas maltophilia [Offenlegungsschrift] T1 - Agents containing proteases from Stenotrophomonas maltophilia [Europäische Patentanmeldung / US Patentanmeldung / Internationale Patentanmeldung] Y1 - 2009 SP - 1 EP - 47 PB - Deutsches Patent- und Markenamt / Europäisches Patentamt / USPTO / WIPO CY - München / Den Hague / Washington / Genf ER - TY - JOUR A1 - Glaser, Stefan A1 - Lubitz, Sandra A1 - Loveland, Kate L. A1 - Ohbo, Kazu A1 - Robb, Lorraine A1 - Schwenk, Frieder A1 - Seibler, Jost A1 - Roellig, Daniela A1 - Kranz, Andrea A1 - Anastassiadis, Konstantinos A1 - Stewart, A. Francis T1 - The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis JF - Epigenetics & Chromatin Y1 - 2009 U6 - http://dx.doi.org/10.1186/1756-8935-2-5 SN - 1756-8935 VL - 2 IS - 5 SP - 1 EP - 16 ER - TY - JOUR A1 - Kotnik, Katarina A1 - Popova, Elena A1 - Todiras, Mihail A1 - Mori, Marcelo A. A1 - Alenina, Natalia A1 - Seibler, Jost A1 - Bader, Michael T1 - Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown JF - Plos One Y1 - 2009 U6 - http://dx.doi.org/10.1371/journal.pone.0005124 VL - 4 IS - 4 SP - e5124 PB - Plos CY - San Francisco, California, US ER - TY - JOUR A1 - Graf, Alain-Michel A1 - Steinhof, Rafael A1 - Lotz, Martin A1 - Tippkötter, Nils A1 - Kasper, Cornelia A1 - Beutel, Sascha A1 - Ulber, Roland T1 - Downstream-Processing mit Membranadsorbern zur Isolierung nativer Proteinfraktionen aus Kartoffelfruchtwasser JF - Chemie Ingenieur Technik N2 - Bei der Stärkeproduktion entstehendes Kartoffelfruchtwasser besitzt mit 2 – 3 % einen hohen Anteil an ernährungsphysiologisch interessanten Proteinen. Die industrielle Gewinnung dieser Proteinfracht liefert jedoch lediglich ein minderwertiges, denaturiertes Produkt. Mit Hilfe der Membranadsorber-Technologie lassen sich aus Kartoffelfruchtwasser unter milden Reaktionsbedingungen native bioaktive Proteinfraktionen gewinnen. Geeignete Trennbedingungen wurden im Labormaßstab entwickelt und in den Technikumsmaßstab übertragen. An Anionenaustauscher-Membranadsorbern mit einer Membranfläche von 10 000 cm2 wurde eine Patatinhaltige Fraktion (44 kDa) mit Bindungskapazitäten von 0,37 mg/cm2 isoliert. Eine niedermolekulare Proteinfraktion mit Protease-Inhibitoren konnte durch Kationenaustauscher-Membranadsorber mit Bindungskapazitäten von 1,00 mg/cm2 gewonnen werden. Sie ist für verschiedenste Applikationen in der pharmazeutischen, kosmetischen und der Nahrungsmittelindustrie interessant z. B. für Appetitzügler oder muskelaufbauende Proteinpräparate. Der Aufreinigung der nativen Proteinfraktionen durch Ultra-/Diafiltration schließt sich die Konfektionierung durch Sprühtrocknung an. Die bioanalytische Charakterisierung der Produkte belegt die Reinheit und die enzymatische Aktivität sowie die Abreicherung von Störkomponenten wie Glykoalkaloide und Polyphenoloxidasen. Y1 - 2009 U6 - http://dx.doi.org/10.1002/cite.200800139 VL - 81 IS - 3 SP - 267 EP - 274 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Sieker, Tim A1 - Ulber, Roland A1 - Dimitrova, Darina A1 - Bart, Hans-Jörg A1 - Neuner, Andreas A1 - Heinzle, Elmar A1 - Tippkötter, Nils T1 - Silage : Fermentationsrohstoff für die chemische Industrie? JF - labor&more N2 - In Anbetracht des zu erwartenden Rückgangs der Verfügbarkeit fossiler Rohstoffe müssen nicht nur für den Energiesektor, sondern auch für die Herstellung industrieller Produkte alternative Rohstoffe gefunden werden. Ein Beispiel für einen nicht in Nahrungsmittelkonkurrenz stehenden nachwachsenden Rohstoff ist grüne Biomasse wie Gras und Klee. Diese lassen sich in Deutschland auf großen Flächen anbauen und enthalten eine Vielzahl potenzieller Substrate für Fermentationen. Y1 - 2009 IS - 2 SP - 44 EP - 45 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Stückmann, Henning A1 - Kroll, Stephen A1 - Winkelmann, Gunda A1 - Noack, Udo A1 - Scheper, Thomas A1 - Ulber, Roland T1 - A semi-quantitative dipstick assay for microcystin JF - Analytical and Bioanalytical Chemistry N2 - An immunochromatographic lateral flow dipstick assay for the fast detection of microcystin-LR was developed. Colloid gold particles with diameters of 40 nm were used as red-colored antibody labels for the visual detection of the antigen. The new dipstick sensor is capable of detecting down to 5 µg·l−1 (ppb; total inversion of the color signal) or 1 ppb (observation of color grading) of microcystin-LR. The course of the labeling reaction was observed via spectrometric wave shifts caused by the change of particle size during the binding of antibodies. Different stabilizing reagents showed that especially bovine serum albumin (BSA) and casein increase the assays sensitivity and the conjugate stability. Performance of the dipsticks was quantified by pattern processing of capture zone CCD images. Storage stability of dipsticks and conjugate suspensions over 115 days under different conditions were monitored. The ready-to-use dipsticks were successfully tested with microcystin-LR-spiked samples of outdoor drinking- and salt water and applied to the tissue of microcystin-fed mussels. Y1 - 2009 U6 - http://dx.doi.org/10.1007/s00216-009-2750-8 SN - 1618-2650 VL - 394 IS - 3 SP - 863 EP - 869 PB - springer CY - Berlin ER - TY - JOUR A1 - Ulber, Roland A1 - Tippkötter, Nils T1 - Nitratfreie Molke JF - Rundschau für Fleischhygiene und Lebensmittelüberwachung Y1 - 2009 IS - 4 SP - 150 EP - 152 ER - TY - JOUR A1 - Henderson, Colin J. A1 - Scheer, Nico A1 - Wolf, C. Roland T1 - Advances in the generation of mouse models to elucidate the pathways of drug metabolism in rodents and man JF - Expert Review of Clinical Pharmacology Y1 - 2009 U6 - http://dx.doi.org/10.1586/17512433.2.2.105 SN - 1751-2441 VL - 2 IS - 2 SP - 105 EP - 109 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Stanley, Lesley A. A1 - Horsburgh, Brian C. A1 - Ross, Jillian A1 - Scheer, Nico A1 - Wolf, C. Roland T1 - Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior JF - Drug Metabolism Reviews Y1 - 2009 U6 - http://dx.doi.org/10.1080/03602530802605040 SN - 1097-9883 VL - 41 IS - 1 SP - 27 EP - 65 PB - Taylor & Francis CY - London ER - TY - CHAP A1 - Henderson, Colin J. A1 - Wolf, C. Roland A1 - Scheer, Nico ED - Woolf, Thomas F. T1 - The use of transgenic animals to study drug metabolism T2 - Handbook of Drug Metabolism. 2nd Edition Y1 - 2009 SN - 978-1-4200-7647-9 SP - 637 EP - 658 PB - Informa Healthcare CY - New York ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Zoor, Annegreth T1 - A new irreversible enzyme-aided esterification method in organic solvents JF - Biotechnology letters. 30 (2008), H. 5 Y1 - 2008 SN - 1573-6776 SP - 925 EP - 928 ER - TY - JOUR A1 - Elbers, Gereon A1 - Nieren, Monika A1 - Hoffmann, Katharina A1 - Gäb, Martina T1 - Schnellerfassung der Wirkung von Luftschadstoffen auf Pflanzen mit der Nahinfrarotspektroskopie (NIRS). Untersuchung Ammoniak exponierter Gräser und Kräuter / Nieren, Monika ; Hoffmann, Katharina ; Gäb, Martina ; Ooyen, Sven van ; Köllner, Barbara ; Elbe JF - Immissionsschutz. 13 (2008), H. 2 Y1 - 2008 SN - 1430-9262 SP - 82 EP - 90 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Pinkenburg, Olaf T1 - Method of cloning at least one nucleic acid molecule of interest using type IIS restriction endonucleases, and corresponding cloning vectors, kits and system using type IIS restriction endonucleases / Selmer, Thorsten ; Pinkenburg, Olaf Y1 - 2008 N1 - Patent No. WO 2008095927 A1 Aug 14, 2008 ER - TY - BOOK A1 - Jeromin, Günter Erich T1 - Organische Chemie : Ein praxisbezogenes Lehrbuch. Korr. Nachdr. der 2. Aufl. Y1 - 2008 SN - 3-8171-1732-9 PB - Deutsch CY - Frankfurt am Main ER - TY - PAT A1 - Jeromin, Günter Erich A1 - Schwarzer, Klemens T1 - Neuer Wärmeträger für Solaranlagen : Offenlegungsschrift : DE 102007016738 A1 ; Offenlegungstag: 09.10.2008 Y1 - 2008 N1 - Volltext über Datenbank DEPATISnet: http://depatisnet.dpma.de/DepatisNet/depatisnet?action=pdf&docid=DE102007016738A1 PB - Deutsches Patent- und Markenamt CY - München ER - TY - PAT A1 - Mang, Thomas A1 - Krombholz, Markus A1 - Hoffmüller, Winfried A1 - Burchard, Theodor T1 - Verfahren zur Herstellung von Sicherheitsfolien : Offenlegungschrift DE 102007055112 A1 ; Offenlegungstag 10.07.2008 / Krombholz, Markus ; Mang, Thomas ; Hoffmüller, Winfried ; Burchard, Theodor ; Heim, Manfred Y1 - 2008 N1 - Volltext über Datenbank: http://publikationen.dpma.de/ PB - Deutsches Patent- und Markenamt CY - München ER - TY - PAT A1 - Siegert, Petra A1 - Wieland, Susanne A1 - Engelskirchen, Julia A1 - Merkel, Marion A1 - Maurer, Karl-Heinz A1 - Bessler, Cornelius T1 - Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift] T1 - Novel alkaline protease from Bacillus Gibsonii and washing and cleaning agents containing said novel alkaline protease [Europäische Patentanmeldung / US Patentanmeldung / Internationale Patentanmeldung] Y1 - 2008 SP - 1 EP - 51 PB - Deutsches Patentamt / Europäisches Patentamt / WIPO CY - München / Den Hague / Genf ER - TY - JOUR A1 - Herold, Marco J. A1 - Brandt, Jens van den A1 - Seibler, Jost A1 - Reichardt, Holger M. T1 - Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats JF - Proceedings of the National Academy of Sciences of the United States of America Y1 - 2008 U6 - http://dx.doi.org/10.1073/pnas.0806213105 SN - 1091-6490 VL - 105 IS - 47 SP - 18507 EP - 18512 ER - TY - JOUR A1 - Koch, Linda A1 - Wunderlich, F. Thomas A1 - Seibler, Jost A1 - Könner, A. Christine A1 - Hampel, Brigitte A1 - Irlenbusch, Sigrid A1 - Brabant, Georg A1 - Kahn, C. Ronald A1 - Schwenk, Frieder A1 - Brüning, Jens C. T1 - Central insulin action regulates peripheral glucose and fat metabolism in mice JF - The Journal of Clinical Investigation (JCI) Y1 - 2008 U6 - http://dx.doi.org/10.1172/JCI31073 SN - 1558-8238 VL - 118 IS - 6 SP - 2132 EP - 2147 ER - TY - JOUR A1 - Christoph, Thomas A1 - Bahrenberg, Gregor A1 - Vry, Jean de A1 - Englberger, Werner A1 - Erdmann, Volker A. A1 - Frech, Moritz A1 - Kögel, Babette A1 - Röhl, Thomas A1 - Schiene, Klaus A1 - Schröder, Wolfgang A1 - Seibler, Jost A1 - Kurreck, Jens T1 - Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice JF - Molecular and Cellular Neuroscience Y1 - 2008 U6 - http://dx.doi.org/10.1016/j.mcn.2007.12.006 SN - 1044-7431 VL - 37 IS - 3 SP - 579 EP - 589 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Deterding, A. A1 - Ulber, Roland T1 - Determination of acetic acid in fermentation broth by gas-diffusion technique JF - Engineering in Life Sciences N2 - Due to the interfering effects of acetic acid in many fermentation processes, a gas-diffusion technique was developed for the online determination of acetic acid. The measurements were accomplished with a flow diffusion analysis (FDA) unit from the TRACE Analytics GmbH, Braunschweig, Germany. The diffusion analysis is based on the UV-absorbance of acetic acid at 205 nm. The measurement was achieved by the separation of an acceptor and a carrier stream (acidified fermentation broth) using a gas permeable polytetrafluoroethylene (PTFE) membrane, whereby broth constituents that would otherwise disturb the UV-measurement of acetic acid, are held back efficiently. Merely, the fermentation by-products, e.g. formic acid, is capable of diffusing through the membrane. While formic acid can disturb the measurement, carbon dioxide does not absorb at 205 nm. The method operates with time-dependent sample enrichment. During the analysis, a small volume of the acceptor stream is stopped for a defined time interval in the acceptor chamber. During this period, the gaseous acetic acid diffuses through the membrane and is enriched in the acceptor chamber. Subsequently after the enrichment, the acceptor stream flows through a UV-detector. The intensity of the signal is proportional to the acetic acid concentration. Online measurements in bioreactors via a sterile filtration probe have been accomplished. A linear calibration in the range of 0.5–5.0 g/L acetic acid with a relative standard deviation of <5 % was obtained. A sampling rate of 8 samples per hour was possible. The system was applied for the determination of acetic acid in E. coli fermentation broth. The instrument is easy to clean, very user-friendly and does not require any toxic or expensive reagents. Y1 - 2008 U6 - http://dx.doi.org/10.1002/elsc.200820227 VL - 8 IS - 1, Special Issue: Technical Systems for the Use in Life Sciences SP - 62 EP - 67 ER - TY - CHAP A1 - Tippkötter, Nils A1 - Schünemann, V. A1 - Christmann, R. A1 - Pasteur, A. A1 - Schweizer, J. A1 - Ulber, R. ED - Beckmann, Dieter T1 - Bioaffinity Layering magnetisierbarer Mikro- und Nanopartikel T2 - Technische Systeme für die Lebenswissenschaften : 14. Heiligenstädter Kolloquium, Heilbad Heiligenstadt, 22.09. - 24.09.2008 Y1 - 2008 SN - 978-3-00-025695-0 SP - 97 EP - 98 CY - Heiligenstadt ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, W. A1 - Ulber, R. T1 - Nitrate removal from whey concentrate with biotechnological regeneration of the waste water JF - European dairy magazine : EDM Y1 - 2008 SN - 0936-6318 IS - 1 SP - 30 EP - 32 ER - TY - JOUR A1 - Ulber, R. A1 - Tippkötter, Nils A1 - Buchholz, H. A1 - Demmer, W. A1 - Scheper, T. T1 - Innovative Verfahren in der Molkeaufarbeitung zur Gewinnung neuer Produkte JF - Deutsche Milchwirtschaft Y1 - 2008 SN - 0012-0480 VL - 59 IS - 19 SP - 704 EP - 706 ER - TY - CHAP A1 - Tippkötter, Nils A1 - Roikaew, W. A1 - Ulber, R. T1 - An automated pilot plant for the bioengineering processing of concentrated whey T2 - European BioPerspectives : in cooperation with BIOTECHNICA 2008 : 7 - 9 October 2008 Hannover, Germany ; book of abstracts ; abstracts, poster programme Y1 - 2008 SP - 98 PB - Dechema CY - Frankfurt am Main ER - TY - JOUR A1 - Scheer, Nico A1 - Ross, Jillian A1 - Rode, Anja A1 - Zevnik, Branko A1 - Niehaves, Sandra A1 - Faust, Nicole A1 - Wolf, C. Roland T1 - A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response JF - Journal of Clinical Investigation Y1 - 2008 U6 - http://dx.doi.org/https://doi.org/10.1172/JCI35483 SN - 1558-8238 VL - 118 IS - 9 SP - 3228 EP - 3239 ER - TY - JOUR A1 - Wagner, Torsten A1 - Beging, Stefan A1 - Rotter, L. A1 - Poghossian, Arshak A1 - Biselli, Manfred A1 - Zang, Werner A1 - Schöning, Michael Josef T1 - Online-Messsysteme für die automatisierte Charakterisierung von feldeffektbasierten Biosensoren JF - 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.) Y1 - 2007 SN - 978-3-940046-45-1 N1 - Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29 SP - 257 EP - 260 PB - TUDpress, Verl. der Wissenschaften CY - Dresden ER - TY - JOUR A1 - Mang, Thomas A1 - Roosen, Christoph A1 - Ansorge-Schumacher, Marion A1 - Leitner, Walter T1 - Gaining pH-control in water/carbon dioxide biphasic systems / Roosen, Christoph ; Ansorge-Schumacher, Marion ; Mang, Thomas ; Leitner, Walter ; Greiner, Lasse JF - Green Chemistry. 9 (2007) Y1 - 2007 SN - 1463-9262 SP - 455 EP - 458 ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Martins, J. A1 - Kremer, K. T1 - Investigation of the Elastomer-Foam Production with Single-Sided NMR / Kolz, J. ; Martins, J. ; Kremer, K. ; Mang, Thomas ; Blümich, B. JF - Kautschuk Gummi Kunststoffe. 60 (2007), H. 4 Y1 - 2007 SN - 0948-3276 SP - 179 EP - 183 ER - TY - PAT A1 - Jeromin, Günter Erich T1 - Enzymkatalysierte irreversible Veresterung von Carbonsäuren in organischem Lösungsmittel : Offenlegungsschrift DE102005061737A1 ; Offenlegungstag: 05.07.2007 Y1 - 2007 N1 - Volltext über Datenbank: http://publikationen.dpma.de/ PB - Deutsches Patent- und Markenamt CY - München ER - TY - JOUR A1 - Biselli, Manfred A1 - Rechmann, Hanrik A1 - Friedrich, Andrea A1 - Forouzan, Dara T1 - Characterization of photosynthetically active duckweed ( Wolffia australiana ) in vitro culture by Respiration Activity Monitoring System (RAMOS) / Henrik Rechmann, Andrea Friedrich, Dara Forouzan, Stefan Barth, Heide Schnabl, Manfred Biselli und Robert B JF - Biotechnology Letters. 29 (2007), H. 6 Y1 - 2007 SN - 0141-5492 SP - 971 EP - 977 ER - TY - JOUR A1 - Turek, Monika A1 - Ketterer, Lothar A1 - Claßen, Melanie A1 - Berndt, Heinz A1 - Elbers, Gereon A1 - Krüger, Peter A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Development and Electrochemical Investigations of an EIS-(Electrolyte-Insulator-Semiconductor) based Biosensor for Cyanide Detection JF - Sensors Y1 - 2007 SN - 1424-8220 VL - 7 IS - 8 SP - 1415 EP - 1426 ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, Roberto A1 - Yoshinobu, Tatsuo A1 - Kloock, Joachim P. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Schöning, Michael Josef T1 - Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications JF - Electrochimica Acta. 53 (2007), H. 2 Y1 - 2007 SN - 0013-4686 SP - 305 EP - 311 ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, R. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells JF - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) Y1 - 2007 SN - 1-4244-0841-5 N1 - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon SP - 1107 EP - 1110 PB - IEEE CY - Piscataway ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Goga, N. A1 - Casanova, F. T1 - Spatial localization with single-sided NMR sensors / Kolz, J. ; Goga, N. ; Casanova, F. ; Mang, T. ; Blümich, B. JF - Applied Magnetic Resonance. 32 (2007), H. 1-2 Y1 - 2007 SN - 0937-9347 SP - 171 EP - 184 ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Hunger, K. A1 - Rath, S. T1 - Investigation of self-diffusion processes in ionic hydrogels with a single-sided sensor / Kolz, J. ; Hunger, K. ; Rath, S. ; Mang, T. ; Blümich, B. JF - Magnetic Resonance Imaging. 25 (2007), H. 4 Y1 - 2007 SN - 0730-725X N1 - Proceedings of the Eighth International Bologna Conference on Magnetic Resonance in Porous Media SP - 566 EP - 567 ER - TY - PAT A1 - Jeromin, Günter Erich T1 - Denk- und Lernspielzeug : Offenlegungsschrift : DE 102006003433 A1 ; Offenlegungstag: 26.07.2007 Y1 - 2007 N1 - Volltext über Datenbank: http://publikationen.dpma.de/ PB - Deutsches Patent- und Markenamt CY - München ER - TY - PAT A1 - Bessler, Cornelius A1 - Maurer, Karl-Heinz A1 - Merkel, Marion A1 - Siegert, Petra A1 - Wieland, Susanne T1 - Subtilisin aus Bacillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin [Offenlegungsschrift] T1 - Subtilisin from Bacillus pumilus and washing and cleaning agents containing said novel subtilisin [Europäische Patentanmeldung / Internationale Patentanmeldung / Kanadische Patentanmeldung] Y1 - 2007 SP - 1 EP - 47 PB - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO / CIPO CY - München / Den Hague / Genf ER - TY - CHAP A1 - Wendorff, Marion A1 - Eggert, Thorsten A1 - Pohl, Martina A1 - Dresen, Carola A1 - Müller, Michael A1 - Jaeger, Karl-Erich A1 - Sprenger, Georg A. A1 - Schürmann, Melanie A1 - Schürmann, Martin A1 - Johnen, Sandra A1 - Sprenger, Gerda A1 - Sahm, Hermann A1 - Inoue, Tomoyuki A1 - Schörken, Ulrich A1 - Breittaupt, Holger A1 - Frölich, Bettina A1 - Heim, Petra A1 - Iding, Hans A1 - Juchem, Bettina A1 - Siegert, Petra A1 - Kula, Maria-Regina A1 - Weckbecker, Andrea A1 - Hummel, Werner A1 - Fessner, Wolf-Dieter A1 - Elling, Lothar A1 - Wolberg, Michael A1 - Bode, Silke A1 - Feldmann, Ralf A1 - Geilenkirchen, Petra A1 - Schubert, Thomas A1 - Walter, Lydia A1 - Dünnwald, Thomas A1 - Demir, Ayhan S. A1 - Kolter-Jung, Doris A1 - Nitsche, Adam A1 - Dünkelmann, Pascal A1 - Cosp, Annabel A1 - Lingen, Bettina T1 - Catalytic asymmetric synthesis : section 2.2 T2 - Asymmetric synthesis with chemical and biological methods / ed. by Dieter Enders ... Y1 - 2007 SN - 978-3-527-31473-7 SP - 298 EP - 413 PB - Wiley-VCH CY - Weinheim ER - TY - PAT A1 - O'Connell, Timothy A1 - Hoven, Nina A1 - Siegert, Petra A1 - Maurer, Karl-Heinz T1 - Amadoriasen in Wasch- und Reinigungsmitteln [Offenlegungsschrift] T1 - Amadoriases in washing and cleaning products [Europäische Patentanmeldung / Internationale Patentanmeldung] Y1 - 2007 SP - 1 EP - 45 PB - Deutsches Patent- und Markenamt / Europäisches Patentamt / WIPO CY - München / Den Hague / Genf ER - TY - JOUR A1 - Seibler, Jost A1 - Kleinridders, Andre A1 - Küter-Luks, Birgit A1 - Niehaves, Sandra A1 - Brüning, Jens C. A1 - Schwenk, Frieder T1 - Reversible gene knockdown in mice using a tight, inducible shRNA expression system JF - Nucleic Acids Research Y1 - 2007 U6 - http://dx.doi.org/10.1093/nar/gkm122 SN - 1362-4962 VL - 35 IS - 7 SP - e54 ER - TY - JOUR A1 - Kappler-Tanudyaya, Nathalie A1 - Schmitt, Heike A1 - Tippkötter, Nils A1 - Meyer, Lina A1 - Lenzen, Sigurd A1 - Ulber, Roland T1 - Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose JF - Biotechnology Journal N2 - Mannoheptulose is a seven-carbon sugar. It is an inhibitor of glucose-induced insulin secretion due to its ability to selectively inhibit the enzyme glucokinase. An improved procedure for mannoheptulose isolation from avocados is described in this study (based upon the original method by La Forge). The study focuses on the combination of biotransformation and downstream processing (preparative chromatography) as an efficient method to produce a pure extract of mannoheptulose. The experiments were divided into two major phases. In the first phase, several methods and parameters were compared to optimize the mannoheptulose extraction with respect to efficiency and purity. In the second phase, a mass balance of mannoheptulose over the whole extraction process was undertaken to estimate the yield and efficiency of the total extraction process. The combination of biotransformation and preparative chromatography allowed the production of a pure mannoheptulose extract. In a biological test, the sugar inhibited the glucokinase enzyme activity efficiently. Y1 - 2007 U6 - http://dx.doi.org/10.1002/biot.200700004 SN - 1860-7314 VL - 2 IS - 6 SP - 692 EP - 699 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, N. A1 - Ulber, R. T1 - Nitratentfernung aus Molkekonzentrat mit biotechnologischer Regeneration der Abwässer JF - Deutsche Milchwirtschaft Y1 - 2007 SN - 0012-0480 VL - 58 IS - 15 SP - 540 EP - 542 ER -