TY - JOUR A1 - Wagner, Torsten A1 - Molina, R. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells JF - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) Y1 - 2007 SN - 1-4244-0841-5 N1 - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon SP - 1107 EP - 1110 PB - IEEE CY - Piscataway ER - TY - JOUR A1 - Werner, Frederik A1 - Krumbe, Christoph A1 - Schumacher, Katharina A1 - Groebel, Simone A1 - Spelthahn, Heiko A1 - Stellberg, Michael A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Selmer, Thorsten A1 - Keusgen, Michael A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1340 EP - 1344 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Turek, Monika A1 - Ketterer, Lothar A1 - Claßen, Melanie A1 - Berndt, Heinz A1 - Elbers, Gereon A1 - Krüger, Peter A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Development and Electrochemical Investigations of an EIS-(Electrolyte-Insulator-Semiconductor) based Biosensor for Cyanide Detection JF - Sensors Y1 - 2007 SN - 1424-8220 VL - 7 IS - 8 SP - 1415 EP - 1426 ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, Roberto A1 - Yoshinobu, Tatsuo A1 - Kloock, Joachim P. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Schöning, Michael Josef T1 - Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications JF - Electrochimica Acta. 53 (2007), H. 2 Y1 - 2007 SN - 0013-4686 SP - 305 EP - 311 ER - TY - JOUR A1 - Werner, Frederik A1 - Groebel, Simone A1 - Schuhmacher, K. A1 - Spelthahn, Heiko A1 - Wagner, Torsten A1 - Selmer, Thorsten A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Bestimmung der metabolischen Aktivität von Mikroorganismen während des Biogasbildungsprozesses JF - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] Y1 - 2009 SN - 978-3-941298-44-6 N1 - Dresdner Sensor-Symposium ; (9, 2009, Dresden) SP - 201 EP - 204 PB - TUDpress CY - Dresden ER - TY - JOUR A1 - Werner, Frederik A1 - Groebel, Simone A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Selmer, Thorsten A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Überwachung der metabolischen Aktivität von Mikroorganismen zur Kontrolle des biologischen Prozesses im Biogasfermenter JF - Biogas 2011 : Energieträger der Zukunft ; 6. Fachtagung, Fachtagung Braunschweig, 08. und 09. Juni 2011 / VDI Energie und Umwelt Y1 - 2011 SN - 978-3-18-092121-1 N1 - Gesellschaft Energie und Umwelt ; Fachtagung Biogas ; (6 : ; 2011.06.08-09 : ; Braunschweig) ; VDI-Berichte ; 2121 SP - 285 EP - 286 PB - VDI-Verl. CY - Düsseldorf ER - TY - JOUR A1 - Pilas, Johanna A1 - Iken, Heiko A1 - Selmer, Thorsten A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Development of a multi‐parameter sensor chip for the simultaneous detection of organic compounds in biogas processes JF - Physica status solidi (a) N2 - An enzyme-based multi-parameter biosensor is developed for monitoring the concentration of formate, d-lactate, and l-lactate in biological samples. The sensor is based on the specific dehydrogenation by an oxidized β-nicotinamide adenine dinucleotide (NAD+)-dependent dehydrogenase (formate dehydrogenase, d-lactic dehydrogenase, and l-lactic dehydrogenase, respectively) in combination with a diaphorase from Clostridium kluyveri (EC 1.8.1.4). The enzymes are immobilized on a platinum working electrode by cross-linking with glutaraldehyde (GA). The principle of the determination scheme in case of l-lactate is as follows: l-lactic dehydrogenase (l-LDH) converts l-lactate into pyruvate by reaction with NAD+. In the presence of hexacyanoferrate(III), the resulting reduced β-nicotinamide adenine dinucleotide (NADH) is then regenerated enzymatically by diaphorase. The electrochemical detection is based on the current generated by oxidation of hexacyanoferrate(II) at an applied potential of +0.3 V vs. an Ag/AgCl reference electrode. The biosensor will be electrochemically characterized in terms of linear working range and sensitivity. Additionally, the successful practical application of the sensor is demonstrated in an extract from maize silage. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431894 SN - 1862-6319 VL - 212 IS - 6 SP - 1306 EP - 1312 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Breuer, Lars A1 - Raue, Markus A1 - Kirschbaum, M. A1 - Mang, Thomas A1 - Schöning, Michael Josef A1 - Thoelen, R. A1 - Wagner, Torsten T1 - Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide JF - Physica status solidi (a) N2 - Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431944 SN - 1862-6319 VL - 212 IS - 6 SP - 1368 EP - 1374 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Pilas, Johanna A1 - Mariano, K. A1 - Keusgen, M. A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes JF - Procedia Engineering Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.08.702 SN - 1877-7058 N1 - Part of special issue "Eurosensors 2015" VL - 120 SP - 532 EP - 535 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Takenaga, Shoko A1 - Schneider, Benno A1 - Erbay, E. A1 - Biselli, Manfred A1 - Schnitzler, Thomas A1 - Schöning, Michael Josef A1 - Wagner, Torsten T1 - Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process JF - Physica status solidi (a) N2 - A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201532053 SN - 1862-6319 VL - 212 IS - 6 SP - 1347 EP - 1352 PB - Wiley CY - Weinheim ER -