TY - JOUR A1 - Pressler, Axel A1 - Esefeld, Katrin A1 - Scherr, Johannes A1 - Ali, Mohammad A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Halle, Martin A1 - Kaemmerer, Harald A1 - Schmidt-Trucksäss, Arno A1 - Hager, Alfred T1 - Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation JF - The American Journal of Cardiology N2 - Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5%, first to third quartile 2.1% to 4.5% vs 3.6%, first to third quartile 2.2% to 4.3%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients. Y1 - 2010 U6 - https://doi.org/10.1016/j.amjcard.2009.10.070 SN - 0002-9149 VL - 105 IS - 5 SP - 740 EP - 744 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Schmidt-Trucksäss, A. A1 - Sitnikova, Diana A1 - Ali, Mohammad A1 - Blume, Katharina A1 - Halle, Martin A1 - Hansser, Henner T1 - Dynamic retinal vessel response to flicker in obesity: A methodological approach JF - Microvascular Research Y1 - 2011 SN - 0026-2862 VL - 81 IS - 1 SP - 123 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hanssen, H. A1 - Nickel, T. A1 - Drexel, V. A1 - Hertel, G. A1 - Emslander, I. A1 - Sisic, Z. A1 - Lorang, D. A1 - Schuster, T. A1 - Kotliar, Konstantin A1 - Pressler, A. A1 - Schmidt-Trucksäss, A. A1 - Weis, M. A1 - Halle, M. T1 - Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity JF - Atherosclerosis Y1 - 2011 SN - 0021-9150 VL - 216 IS - 2 SP - 433 EP - 439 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Lanzl, I. A1 - Seidova, S.-F. A1 - Dühring, C. von A1 - Kotliar, Konstantin ED - Erb, Carl T1 - Befunde der dynamischen Gefäßanalyse am Auge bei Gesunden und Glaukom-Patienten mit praxisrelevanter Bedeutung T2 - Mikrozirkulation beim Glaukom Y1 - 2009 N1 - Search on Glaucoma SP - 33 EP - 39 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Stadler, Alexander Maximilian A1 - Garvey, Christopher J. A1 - Embs, Jan Peter A1 - Koza, Michael Marek A1 - Unruh, Tobias A1 - Artmann, Gerhard A1 - Zaccai, Guiseppe T1 - Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study JF - Biochimica et biophysica acta (BBA): General Subjects Y1 - 2014 U6 - https://doi.org/10.1016/j.bbagen.2014.06.007 SN - 1872-8006 (E-Journal); 0304-4165 (Print) VL - 1840 IS - 10 SP - 2989 EP - 2999 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Peloni, Alessandro A1 - Dachwald, Bernd A1 - Ceriotti, Matteo T1 - Multiple near-earth asteroid rendezvous mission: Solar-sailing options JF - Advances in Space Research Y1 - 2017 U6 - https://doi.org/10.1016/j.asr.2017.10.017 SN - 0273-1177 IS - In Press, Corrected Proof PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kezerashvili, Roman Ya A1 - Dachwald, Bernd T1 - Preface: Solar sailing: Concepts, technology, and missions II JF - Advances in Space Research Y1 - 2021 U6 - https://doi.org/10.1016/j.asr.2021.01.037 SN - 0273-1177 VL - 67 IS - 9 SP - 2559 EP - 2560 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Seefeldt, Patric A1 - Grundmann, Jan Thimo A1 - Jahnke, Rico A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Ceriotti, Matteo A1 - Dachwald, Bernd A1 - Macdonald, Malcolm A1 - McInnes, Colin A1 - Seboldt, Wolfgang A1 - Quantius, Dominik A1 - Bauer, Waldemar A1 - Wiedemann, Carsten A1 - Grimm, Christian D. A1 - Hercik, David A1 - Ho, Tra-Mi A1 - Lange, Caroline A1 - Schmitz, Nicole T1 - Paths not taken – The Gossamer roadmap’s other options JF - Advances in Space Research KW - Solar sail KW - Small spacecraft KW - DLR-ESTEC GOSSAMER roadmap for solar sailing KW - GOSSAMER-1 Y1 - 2021 U6 - https://doi.org/10.1016/j.asr.2021.01.044 SN - 0273-1177 VL - 67 IS - 9 SP - 2912 EP - 2956 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Grundmann, Jan Thimo A1 - Dachwald, Bernd A1 - Grimm, Christian D. A1 - Kahle, Ralph A1 - Koch, Aaron Dexter A1 - Krause, Christian A1 - Lange, Caroline A1 - Quantius, Dominik A1 - Ulamec, Stephan T1 - Spacecraft for Hypervelocity Impact Research – An Overview of Capabilities, Constraints and the Challenges of Getting There JF - Procedia Engineering Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.04.021 SN - 1877-7058 N1 - Proceedings of the 2015 Hypervelocity Impact Symposium (HVIS 2015) VL - Vol. 103 SP - 151 EP - 158 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Wind and fairness in ski jumping: A computer modelling analysis JF - Journal of Biomechanics N2 - Wind is closely associated with the discussion of fairness in ski jumping. To counter-act its influence on the jump length, the International Ski Federation (FIS) has introduced a wind compensation approach. We applied three differently accurate computer models of the flight phase with wind (M1, M2, and M3) to study the jump length effects of various wind scenarios. The previously used model M1 is accurate for wind blowing in direction of the flight path, but inaccuracies are to be expected for wind directions deviating from the tangent to the flight path. M2 considers the change of airflow direction, but it does not consider the associated change in the angle of attack of the skis which additionally modifies drag and lift area time functions. M3 predicts the length effect for all wind directions within the plane of the flight trajectory without any mathematical simplification. Prediction errors of M3 are determined only by the quality of the input data: wind velocity, drag and lift area functions, take-off velocity, and weight. For comparing the three models, drag and lift area functions of an optimized reference jump were used. Results obtained with M2, which is much easier to handle than M3, did not deviate noticeably when compared to predictions of the reference model M3. Therefore, we suggest to use M2 in future applications. A comparison of M2 predictions with the FIS wind compensation system showed substantial discrepancies, for instance: in the first flight phase, tailwind can increase jump length, and headwind can decrease it; this is opposite of what had been anticipated before and is not considered in the current wind compensation system in ski jumping. Y1 - 2018 U6 - https://doi.org/10.1016/j.jbiomech.2018.05.001 SN - 0021-9290 IS - 75 SP - 147 EP - 153 PB - Elsevier CY - Amsterdam ER -