TY - JOUR A1 - Bohrn, Ulrich A1 - Mucha, Andreas A1 - Werner, Frederik A1 - Trattner, Barbara A1 - Bäcker, Matthias A1 - Krumbe, Christoph A1 - Schienle, Meinrad A1 - Stütz, Evamaria A1 - Schmitt-Landsiedel, Doris A1 - Fleischer, Maximilian A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment JF - Sensors and actuators. B: Chemical Y1 - 2013 SN - 1873-3077 (E-Journal); 0925-4005 (Print) VL - Vol. 182 SP - 58 EP - 65 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Helsper, Christoph A1 - Fissan, H. J. A1 - Franzen, H. ED - Benarie, Michel M. T1 - Particle Size Distributions of Combustion Aerosols T2 - Atmospheric Pollution 1978 : Proceedings of the 13th International Colloquium; 25-28 April 1978; Paris, France; Edited by Michel M. Benarie N2 - It has been observed that carcinogenic polycyclic aromatic hydrocarbons (PAH) are present in the atmosphere. Combustion processes are considered the most important sources for PAH. Among these, the burning of coal produces the highest emission, but in cities with high traffic density and low meteorological exchange activities, vehicle emissions determine the immission situation, especially in narrow streets. For estimating the potential health effects caused by PAH, it is sufficient to characterize the emission of PAH with respect to their physical state, concentrations, and, as far as the particulate phase is concerned, size distribution. The size distribution is important for transport phenomena, inhalation, and deposition in the respiratory tract. These parameters mainly depend on the combustion system, on system operating conditions, on the exhaust system, and on exhaust cooling conditions. At exhaust-gas temperatures in the range of ambient air temperatures, almost the whole emission of PAH is made up of particulate matter. Y1 - 1978 SN - 0-444-41691-9 U6 - https://doi.org/10.1016/S0166-1116(08)71583-8 SP - 263 EP - 266 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wagner, Torsten A1 - Werner, Frederik A1 - Miyamoto, K. A1 - Schöning, Michael Josef A1 - Yoshinobu, T. T1 - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control JF - Procedia Chemistry. 1 (2009), H. 1 Y1 - 2009 SN - 1876-6196 N1 - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 SP - 1483 EP - 1486 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Mimura, Shuhei A1 - Kanoh, Shin`ichiro A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - Constant-phase-mode operation of the light-addressable potentiometric sensor JF - Procedia Chemistry. 1 (2009), H. 1 Y1 - 2009 SN - 1876-6196 N1 - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 SP - 1487 EP - 1490 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Turek, M. A1 - Heiden, W. A1 - Riesen, A. A1 - Chhabda, T. A. A1 - Schubert, J. A1 - Krüger, P. A1 - Keusgen, M. T1 - Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors JF - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI Y1 - 2009 SN - 0013-4686 SP - 6082 EP - 6088 PB - Elsevier CY - New York ER - TY - JOUR A1 - Wagner, Torsten A1 - Werner, Frederik A1 - Miyamoto, Ko-Ichiro A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 124 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Mimura, Shuhei A1 - Kanoh, Shiníchiro A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - Constant-phase-mode operation of the light-addressable potentiometric sensor JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 119 EP - 123 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, Bin A1 - Spelthahn, Heiko A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 257 EP - 263 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Kanoh, Shin`ichiro A1 - Schöning, Michael Josef T1 - Phase-mode LAPS and its application to chemical imaging JF - Sensors and Actuators B: Chemical. 154 (2011), H. 1 Y1 - 2011 SN - 1873-3077 SP - 28 EP - 32 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Damm, Alexander A1 - Erler, André A1 - Hillen, Walter A1 - Meroni, Michele A1 - Schaepman, Michael E. A1 - Verhoef, Wout A1 - Rascher, Uwe T1 - Modeling the impact of spectral sensor configurations on the FLD retrieval accuracy of sun-induced chlorophyll fluorescence JF - Remote Sensing of Environment Y1 - 2011 SN - 0034-4257 VL - 115 IS - 8 SP - 1882 EP - 1892 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Probability of lightning strikes to air-terminations of structures using the electro-geometrical model theory and the statistics of lightning current parameters JF - Atmospheric Research. 104 (2011) Y1 - 2011 SN - 0169-8095 N1 - Article in Press PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schiffels, Johannes A1 - Baumann, Marcus A1 - Selmer, Thorsten T1 - Facile analysis of short-chain fatty acids as 4-nitrophenyl esters in complex anaerobic fermentation samples by high performance liquid chromatography JF - Journal of Chromatography A. 1218 (2011), H. 34 Y1 - 2011 SN - 0021-9673 SP - 5848 EP - 5851 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Lustfeld, H. A1 - Pithan, C. A1 - Reißel, Martin T1 - Metallic electrolyte composites in the framework of the brick-layer model JF - Journal of the European Ceramic Society N2 - It is well known that the already large dielectric constants of some electrolytes like BaTiO₃ can be enhanced further by adding metallic (e.g. Ni, Cu or Ag) nanoparticles. The enhancement can be quite large, a factor of more than 1000 is possible. The consequences for the properties will be discussed in the present paper applying a brick-layer model (BLM) for calculating dc-resistivities of thin layers and a modified one (PBLM) that includes percolation for calculating dielectric properties of these materials. The PBLM results in an at least qualitative description and understanding of the physical phenomena: This model gives an explanation for the steep increase of the dielectric constant below the percolation threshold and why this increase is connected to a dramatic decrease of the breakdown voltage as well as the ability of storing electrical energy. We conclude that metallic electrolyte composites like BaTiO₃ are not appropriate for energy storage. Y1 - 2012 U6 - https://doi.org/10.1016/j.jeurceramsoc.2011.10.017 SN - 0955-2219 VL - 32 IS - 4 SP - 859 EP - 864 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Spiess, Elmar A1 - Wilfried, Reichardt A1 - Alvarez, Gerardo A1 - Gottrup, Marcus A1 - Öhlschläger, Peter T1 - An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma JF - Molecular Therapy Y1 - 2011 SN - 1525-0016 VL - 20 IS - 3 SP - 555 EP - 564 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Olaru, Alexandra Maria A1 - Kowalski, Julia A1 - Sethi, Vaishali A1 - Blümich, Bernhard T1 - Exchange relaxometry of flow at small Péclet numbers in a glass bead pack JF - Journal of Magnetic Resonance (JMR) N2 - In this paper we consider low Péclet number flow in bead packs. A series of relaxation exchange experiments has been conducted and evaluated by ILT analysis. In the resulting correlation maps, we observed a collapse of the signal and a translation towards smaller relaxation times with increasing flow rates, as well as a signal tilt with respect to the diagonal. In the discussion of the phenomena we present a mathematical theory for relaxation exchange experiments that considers both diffusive and advective transport. We perform simulations based on this theory and discuss them with respect to the conducted experiments. KW - NMR exchange relaxometry KW - Low-field NMR Y1 - 2012 U6 - https://doi.org/10.1016/j.jmr.2012.04.015 SN - 1096-0856 VL - 220 SP - 32 EP - 44 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Fischer, Jan-Thomas A1 - Kowalski, Julia A1 - Pudasaini, Shiva P. T1 - Topographic curvature effects in applied avalanche modelling JF - Cold Regions Science and Technology N2 - This paper describes the implementation of topographic curvature effects within the RApid Mass MovementS (RAMMS) snow avalanche simulation toolbox. RAMMS is based on a model similar to shallow water equations with a Coulomb friction relation and the velocity dependent Voellmy drag. It is used for snow avalanche risk assessment in Switzerland. The snow avalanche simulation relies on back calculation of observed avalanches. The calibration of the friction parameters depends on characteristics of the avalanche track. The topographic curvature terms are not yet included in the above mentioned classical model. Here, we fundamentally improve this model by mathematically and physically including the topographic curvature effects. By decomposing the velocity dependent friction into a topography dependent term that accounts for a curvature enhancement in the Coulomb friction, and a topography independent contribution similar to the classical Voellmy drag, we construct a general curvature dependent frictional resistance, and thus propose new extended model equations. With three site-specific examples, we compare the apparent frictional resistance of the new approach, which includes topographic curvature effects, to the classical one. Our simulation results demonstrate substantial effects of the curvature on the flow dynamics e.g., the dynamic pressure distribution along the slope. The comparison of resistance coefficients between the two models demonstrates that the physically based extension presents an improvement to the classical approach. Furthermore a practical example highlights its influence on the pressure outline in the run out zone of the avalanche. Snow avalanche dynamics modeling natural terrain curvature centrifugal force friction coefficients. KW - Snow KW - Avalanche Y1 - 2012 U6 - https://doi.org/10.1016/j.coldregions.2012.01.005 SN - 1872-7441 VL - 74-75 SP - 21 EP - 30 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Fateri, Miranda A1 - Hötter, Jan-Steffen A1 - Gebhardt, Andreas T1 - Experimental and Theoretical Investigation of Buckling Deformation of Fabricated Objects by Selective Laser Melting JF - Physics Procedia N2 - Although Selective Laser Melting (SLM) process is an innovative manufacturing method, there are challenges such as inferior mechanical properties of fabricated objects. Regarding this, buckling deformation which is caused by thermal stress is one of the undesired mechanical properties which must be alleviated. As buckling deformation is more observable in hard to process materials, silver is selected to be studied theoretically and experimentally for this paper. Different scanning strategies are utilized and a Finite Element Method (FEM) is applied to calculate the temperature gradient in order to determine its effect on the buckling deformation of the objects from experiments. Y1 - 2012 U6 - https://doi.org/10.1016/j.phpro.2012.10.062 SN - 1875-3892 N1 - Part of special issue "Laser Assisted Net shape Engineering 7 (LANE 2012)" VL - 39 SP - 464 EP - 470 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Werner, Frederik A1 - Takenaga, Shoko A1 - Taki, Hidenori A1 - Sawada, Kazuaki A1 - Schöning, Michael Josef T1 - Comparison of label-free ACh-imaging sensors based on CCD and LAPS JF - Sensors and Actuators B: Chemical (2012) N2 - Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics. Y1 - 2013 SN - 0925-4005 VL - 177 SP - 745 EP - 752 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Suco, Henri-Pierre A1 - Rysstad, Gunnar A1 - Schöning, Michael Josef T1 - Monitoring the microbicidal effectiveness of gaseous hydrogen peroxide in sterilisation processes by means of a calorimetric gas sensor JF - Food control N2 - In the present work, a novel method for monitoring sterilisation processes with gaseous H2O2 in combination with heat activation by means of a specially designed calorimetric gas sensor was evaluated. Therefore, the sterilisation process was extensively studied by using test specimens inoculated with Bacillus atrophaeus spores in order to identify the most influencing process factors on its microbicidal effectiveness. Besides the contact time of the test specimens with gaseous H2O2 varied between 0.2 and 0.5 s, the present H2O2 concentration in a range from 0 to 8% v/v (volume percent) had a strong influence on the microbicidal effectiveness, whereas the change of the vaporiser temperature, gas flow and humidity were almost negligible. Furthermore, a calorimetric H2O2 gas sensor was characterised in the sterilisation process with gaseous H2O2 in a wide range of parameter settings, wherein the measurement signal has shown a linear response against the H2O2 concentration with a sensitivity of 4.75 °C/(% v/v). In a final step, a correlation model by matching the measurement signal of the gas sensor with the microbial inactivation kinetics was established that demonstrates its suitability as an efficient method for validating the microbicidal effectiveness of sterilisation processes with gaseous H2O2. KW - hydrogen peroxide KW - sterilisation KW - Bacillus atrophaeus KW - calorimetric gas sensor Y1 - 2012 U6 - https://doi.org/10.1016/j.foodcont.2012.11.048 SN - 0956-7135 VL - 31 IS - 2 SP - 530 EP - 538 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hardt, Arno A1 - Martin, S. A1 - Meißburger, J. A1 - Retz, R. A1 - Wimmer, J. T1 - The cryopump system of the QQDDQ magnet spectrometer BIG KARL JF - Vacuum N2 - Cryopumps without liquid nitrogen shielding are used to provide a vacuum of 10−6 torr in the spectrometer. The vacuum system is subdivided in three sections that can be separated by valves. The first section (scattering chamber) has a volume of 60 l, two rotation transmissions with 35 cm dia and a sliding seal that allows a rotation of 160° without deteriorating the vacuum. The second section includes the vacuum chambers inside the magnets with 6 × 80 cm cross-section and a length of 1200 cm. The third section (detector box) has a volume of 4300 l and contains a moveable detector system. The gas inside the detector with a pressure of 760 torr is separated from the vacuum by a 15 μm mylar foil with an area of 300 cm2. The detector box can be valved off by a valve with the dimension of 10 × 100 cm. The layout of system is given. The instrumentation and the interlock system are described. First experiences with this system are presented. Y1 - 1978 U6 - https://doi.org/10.1016/S0042-207X(78)80026-8 SN - 1879-2715 (E-Journal); 0042-207X (Print) VL - 28 IS - 10-11 SP - 483 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirstein, Simon A1 - Müller, Karsten A1 - Walecki-Mingers, Mark A1 - Deserno, Thomas M. T1 - Robust adaptive flow line detection in sewer pipes JF - Automation in construction N2 - As part of a novel approach to automatic sewer inspection, this paper presents a robust algorithm for automatic flow line detection. A large image repository is obtained from about 50,000 m sewers to represent the high variability of real world sewer systems. Automatic image processing combines Canny edge detection, Hough transform for straight lines and cost minimization using Dijkstra's shortest path algorithm. Assuming that flow lines are mostly smoothly connected horizontal structures, piecewise flow line delineation is reduced to a process of selecting adjacent line candidates. Costs are derived from the gap between adjacent candidates and their reliability. A single parameter α enables simple control of the algorithm. The detected flow line may precisely follow the segmented edges (α = 0.0) or minimize gaps at joints (α = 1.0). Both, manual and ground truth-based analysis indicate that α = 0.8 is optimal and independent of the sewer's material. The algorithm forms an essential step to further automation of sewer inspection. Y1 - 2012 U6 - https://doi.org/10.1016/j.autcon.2011.05.009 SN - 1872-7891 (E-Journal) ; 0926-5805 (Print) IS - 21 SP - 24 EP - 31 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, K. A1 - Kuwabara, Yohei A1 - Kanoh, Shin'ichiro A1 - Yoshinobu, Tatsuo A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Chemical image scanner based on FDM-LAPS JF - Sensors and Actuators B: Chemical. 137 (2009), H. 2 Y1 - 2009 SN - 0925-4005 SP - 533 EP - 538 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Mang, Thomas A1 - Hodenius, M. A. J. A1 - Schmitz-Rode, T. A1 - Baumann, M. T1 - Absorption of 10-hydroxycamptothecin into the coat of magnetoliposomes / Hodenius, M. A. J. ; Schmitz-Rode, T. ; Baumann, M. ; Ivoanova, G. ; Wong, J. E. ; Mang, T. ; Haulena, F. ; Soenen, S. J. H. ; De Cuyper, M. JF - Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3 Y1 - 2009 SN - 0927-7757 N1 - Colloid and Surface Science for Nanotechnology SP - 20 EP - 23 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schwarzer, Klemens A1 - da Silva, Vieira E. A1 - Hoffschmidt, Bernhard A1 - Schwarzer, T. T1 - A new solar desalination system with heat recovery for decentralised drinking water production JF - Desalination. 248 (2009), H. 1-3 Y1 - 2009 SN - 0011-9164 N1 - Water and Sanitation in International Development and Disaster Relief (WSIDDR) International Workshop Edinburgh, Scotland, UK, 28–30 May 2008 SP - 204 EP - 211 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bohrn, U. A1 - Stütz, E. A1 - Fuchs, K. A1 - Fleischer, M. A1 - Schöning, Michael Josef A1 - Wagner, P. T1 - Monitoring of irritant gas using a whole-cell-based sensor system JF - Sensors and Actuators B: Chemical N2 - Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security. Y1 - 2012 U6 - https://doi.org/10.1016/j.snb.2012.05.088 SN - 0925-4005 VL - 175 SP - 208 EP - 217 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hüning, Felix A1 - Leineweber, A. A1 - Jacobs, H. A1 - Lueken, H. T1 - ε-Fe3N: magnetic structure, magnetization and temperature dependent disorder of nitrogen / Leineweber, A. ; Jacobs, H. ; Hüning, F. ; Lueken, H. ; Schilder, H. ; Kockelmann, W. JF - Journal of Alloys and Compounds. 288 (1999), H. 1-2 N2 - ε-Fe3N has been investigated by time-of-flight neutron diffraction (temperature range 4.2–618 K) and SQUID magnetometry (2–700 K, B≤5 T). A ferromagnetic spin structure is observed with magnetic moments oriented perpendicular to the c-axis of the hexagonal nuclear structure. The magnetic saturation moment of iron is 2.2 μB at 4.2 K from neutron diffraction and 2.0 μB from magnetic measurements and decreases in a Brillouin-like manner on heating to TC=575 K. Above 450 K an increasing but reversible disorder of the nitrogen partial structure is observed. Y1 - 1999 SN - 1873-4669 VL - 288 IS - 1-2 SP - 79 EP - 87 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Pressler, Axel A1 - Esefeld, Katrin A1 - Scherr, Johannes A1 - Ali, Mohammad A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Halle, Martin A1 - Kaemmerer, Harald A1 - Schmidt-Trucksäss, Arno A1 - Hager, Alfred T1 - Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation JF - The American Journal of Cardiology N2 - Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5%, first to third quartile 2.1% to 4.5% vs 3.6%, first to third quartile 2.2% to 4.3%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients. Y1 - 2010 U6 - https://doi.org/10.1016/j.amjcard.2009.10.070 SN - 0002-9149 VL - 105 IS - 5 SP - 740 EP - 744 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Schmidt-Trucksäss, A. A1 - Sitnikova, Diana A1 - Ali, Mohammad A1 - Blume, Katharina A1 - Halle, Martin A1 - Hansser, Henner T1 - Dynamic retinal vessel response to flicker in obesity: A methodological approach JF - Microvascular Research Y1 - 2011 SN - 0026-2862 VL - 81 IS - 1 SP - 123 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hanssen, H. A1 - Nickel, T. A1 - Drexel, V. A1 - Hertel, G. A1 - Emslander, I. A1 - Sisic, Z. A1 - Lorang, D. A1 - Schuster, T. A1 - Kotliar, Konstantin A1 - Pressler, A. A1 - Schmidt-Trucksäss, A. A1 - Weis, M. A1 - Halle, M. T1 - Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity JF - Atherosclerosis Y1 - 2011 SN - 0021-9150 VL - 216 IS - 2 SP - 433 EP - 439 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Itabashi, Akinori A1 - Kosaka, Naoki A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - High-speed chemical imaging system based on front-side-illuminated LAPS JF - Sensors and actuators B: Chemical N2 - The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the spatial distribution of specific ions on the sensing surface. The conventional chemical imaging system based on the light-addressable potentiometric sensor (LAPS), however, required a long time to obtain a chemical image, due to the slow mechanical scan of a single light beam. For high-speed imaging, a plurality of light beams modulated at different frequencies can be employed to measure the ion concentrations simultaneously at different locations on the sensor plate by frequency division multiplex (FDM). However, the conventional measurement geometry of back-side illumination limited the bandwidth of the modulation frequency required for FDM measurement, because of the low-pass filtering characteristics of carrier diffusion in the Si substrate. In this study, a high-speed chemical imaging system based on front-side-illuminated LAPS was developed, which achieved high-speed spatiotemporal recording of pH change at a rate of 70 frames per second. Y1 - 2013 U6 - https://doi.org/10.1016/j.snb.2013.03.016 SN - 1873-3077 VL - 182 SP - 315 EP - 321 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Uni- and bi-axial deformation behavior of laser welded advanced high strength steel sheets JF - Journal of materials processing technology N2 - Bead-on-plate butt joints of 2.5 mm hot rolled DP600/DP600 and 1.2 mm cold rolled TRIP700/TRIP700 steel sheets were performed using 6 kW CO2 laser beam welding. The welding speed ranged from 1.5 to 3.0 and from 2.1 to 3.9 m/min in DP/DP and TRIP/TRIP steel weldments respectively. A top surface helium gas was used as a shielding gas at a flow rate of 20 l/min. Metallographic examinations and transverse tensile testing (DIN EN 895: 1995) were carried out to characterize the weldments. The formability of base metals and weldments were investigated by standard Erichsen test (DIN EN ISO 20482). It was found that the uniaxial plastic behavior of both DP600 and TRIP700 base metals was in agreement with Swift and modified Mecking–Kocks models respectively. In a perpendicular tensile test to the weld line, all specimens were fractured at the base metal however the strengths were somewhat higher than those of base metal. There was a significant reduction in formability caused by welding of both DP/DP and TRIP/TRIP steel weldments and the formability has been improved with the increase of the welding speed. Y1 - 2010 U6 - https://doi.org/http10.1016/j.jmatprotec.2010.08.003 SN - 0924-0136 VL - 210 IS - 15 SP - 2188 EP - 2196 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Shielding gas influences on laser weldability of tailored blanks of advanced automotive steels JF - Applied surface science N2 - The effects of shielding gas types and flow rates on CO2 laser weldability of DP600/TRIP700 steel sheets were studied in this work. The evaluated shielding gases were helium (He), argon (Ar) and different mixtures of He and Ar. Weld penetration, tensile strength and formability (Erichsen test) of laser welds were found to be strongly dependent upon the shielding gas types. The ability of shielding gas in removing plasma plume and thus increasing weld penetration is believed to be closely related to ionization potential and atomic weight which determine the period of plasma formation and disappearance. It was found that the higher helium shielding gas flow rate, the deeper weld penetration and the lower weld width. Y1 - 2010 U6 - https://doi.org/10.1016/j.apsusc.2010.08.042 SN - 0169-4332 (E-Journal); 0169-4332 (Print) VL - 257 IS - 5 SP - 1401 EP - 1406 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Roesner, Andreas A1 - Scheik, Sven A1 - Olowinsky, Alexander A1 - Gillner, Arnold A1 - Reisgen, Uwe A1 - Schleser, Markus T1 - Laser assisted joining of plastic metal hybrids JF - Lasers in manufacturing 2011 : proceedings of the sixth International WLT Conference on Lasers in Manufacturing, Munich, May 23 - 26 2011. (Physics procedia ; Vol. 12 (2011), Part B) Y1 - 2011 SN - 1875-3892 (E-Journal); 1875-3884 (Print) SP - 370 EP - 377 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Statistical modeling of laser welding of DP/TRIP steel sheets JF - Optics and laser technology N2 - In this research work, a statistical analysis of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets was done using response surface methodology. The analysis considered the effect of laser power (2–2.2 kW), welding speed (40–50 mm/s) and focus position (−1 to 0 mm) on the heat input, the weld bead geometry, uniaxial tensile strength, formability limited dome height and welding operation cost. The experimental design was based on Box–Behnken design using linear and quadratic polynomial equations for predicting the mathematical models. The results indicate that the proposed models predict the responses adequately within the limits of welding parameters being used and the welding speed is the most significant parameter during the welding process. Y1 - 2012 U6 - https://doi.org/10.1016/j.optlastec.2011.05.025 SN - 1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print) VL - 44 IS - 1 SP - 92 EP - 101 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Optimization of laser welding of DP/TRIP steel sheets using statistical approach JF - Optics and laser technology N2 - Generally, the quality of a weld joint is directly influenced by the welding input parameter settings. Selection of proper process parameters is important to obtain the desired weld bead profile and quality. In this research work, numerical and graphical optimization techniques of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets were carried out using response surface methodology (RSM) based on Box–Behnken design. The procedure was established to improve the weld quality, increase the productivity and minimize the total operation cost by considering the welding parameters range of laser power (2–2.2 kW), welding speed (40–50 mm/s) and focus position (−1 to 0 mm). It was found that, RSM can be considered as a powerful tool in experimental welding optimization, even when the experimenter does not have a model for the process. Strong, efficient and low cost weld joints could be achieved using the optimum welding conditions. Y1 - 2012 U6 - https://doi.org/10.1016/j.optlastec.2011.06.028 SN - 1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print) VL - 44 IS - 1 SP - 255 EP - 262 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ramazani, Ali A1 - Li, Yang A1 - Mukherjee, Krishnendu A1 - Prahl, Ulrich A1 - Bleck, Wolfgang A1 - Abdurakhmanov, Aydemir A1 - Schleser, Markus A1 - Reisgen, Uwe T1 - Microstructure evolution simulation in hot rolled DP600 steel during gas metal arc welding JF - Computational materials science Y1 - 2013 SN - 1879-0801 (E-Book); 0927-0256 (Print) VL - Vol. 68 SP - 107 EP - 116 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bandodkar, Amay J. A1 - Molinnus, Denise A1 - Mirza, Omar A1 - Guinovart, Tomas A1 - Windmiller, Joshua R. A1 - Valdes-Ramirez, Gabriela A1 - Andrade, Francisco J. A1 - Schöning, Michael Josef A1 - Wang, Joseph T1 - Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring JF - Biosensors and bioelectronics N2 - This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains. Y1 - 2014 U6 - https://doi.org/10.1016/j.bios.2013.11.039 SN - 1873-4235 (E-Journal); 0956-5663 (Print) VL - 54 SP - 603 EP - 609 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dikta, Gerhard T1 - Asymptotically efficient estimation under semi-parametric random censorship models JF - Journal of multivariate analysis N2 - We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan–Meier estimator. In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model. Y1 - 2014 U6 - https://doi.org/10.1016/j.jmva.2013.10.002 SN - 1095-7243 (E-Journal); 0047-259X (Print) VL - 124 SP - 10 EP - 24 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Döring, Bernd A1 - Kendrick, C. A1 - Lawson, R. M. T1 - Thermal capacity of composite floor slabs JF - Energy and buildings Y1 - 2013 SN - 1872-6178 (E-Journal); 0378-7788 (Print) VL - Vol. 67 SP - 531 EP - 539 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Hirayama, Yuji A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor JF - Electrochimica acta Y1 - 2013 SN - 1873-3859 (E-Journal); 0013-4686 (Print) SP - Publ. online PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Lanzl, I. A1 - Seidova, S.-F. A1 - Dühring, C. von A1 - Kotliar, Konstantin ED - Erb, Carl T1 - Befunde der dynamischen Gefäßanalyse am Auge bei Gesunden und Glaukom-Patienten mit praxisrelevanter Bedeutung T2 - Mikrozirkulation beim Glaukom Y1 - 2009 N1 - Search on Glaucoma SP - 33 EP - 39 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dankelmann, Peter A1 - Hellwig, Angelika A1 - Volkmann, Lutz T1 - Inverse degree and edge-connectivity JF - Discrete mathematics Y1 - 2009 SN - 1872-681X (E-Journal); 0012-365X (Print) VL - Vol. 309 IS - Iss. 9 SP - 2943 EP - 2947 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dutta, Suryendu A1 - Hartkopf-Fröder, Christoph A1 - Witte, Karin A1 - Brocke, Rainer A1 - Mann, Ulrich T1 - Molecular characterization of fossil palynomorphs by transmission micro-FTIR spectroscopy: implications for hydrocarbon source evaluation JF - International journal of coal geology Y1 - 2013 SN - 1872-7840 (E-Journal); 0166-5162 (Print) VL - Vol. 115 SP - 13 EP - 23 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Funke, Harald A1 - Dickhoff, J. A1 - Keinz, Jan A1 - Anis, H. A. A1 - Parente, A. A1 - Hendrick, P. T1 - Experimental and numerical study of the micromix combustion principle applied for hydrogen and hydrogen-rich syngas as fuel with increased energy density for industrial gas turbine applications JF - Energy procedia N2 - The Dry Low NOx (DLN) Micromix combustion principle with increased energy density is adapted for the industrial gas turbine APU GTCP 36-300 using hydrogen and hydrogen-rich syngas with a composition of 90%-Vol. hydrogen (H₂) and 10%-Vol. carbon-monoxide (CO). Experimental and numerical studies of several combustor geometries for hydrogen and syngas show the successful advance of the DLN Micromix combustion from pure hydrogen to hydrogen-rich syngas. The impact of the different fuel properties on the combustion principle and aerodynamic flame stabilization design laws, flow field, flame structure and emission characteristics is investigated by numerical analysis using a hybrid Eddy Break Up combustion model and validated against experimental results. Y1 - 2014 U6 - https://doi.org/10.1016/j.egypro.2014.12.201 SN - 1876-6102 (E-Journal) IS - 61 SP - 1736 EP - 1739 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ribitsch, D. A1 - Heumann, S. A1 - Karl, W. A1 - Gerlach, J. A1 - Leber, R. A1 - Birner-Gruenberger, R. A1 - Gruber, K. A1 - Eiteljoerg, I. A1 - Remler, P. A1 - Siegert, Petra A1 - Lange, J. A1 - Maurer, Karl-Heinz A1 - Berg, G. A1 - Guebitz, G. M. A1 - Schwab, H. T1 - Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli JF - Journal of biotechnology N2 - A large strain collection comprising antagonistic bacteria was screened for novel detergent proteases. Several strains displayed protease activity on agar plates containing skim milk but were inactive in liquid media. Encapsulation of cells in alginate beads induced protease production. Stenotrophomonas maltophilia emerged as best performer under washing conditions. For identification of wash-active proteases, four extracellular serine proteases called StmPr1, StmPr2, StmPr3 and StmPr4 were cloned. StmPr2 and StmPr4 were sufficiently overexpressed in E. coli. Expression of StmPr1 and StmPr3 resulted in unprocessed, insoluble protein. Truncation of most of the C-terminal domain which has been identified by enzyme modeling succeeded in expression of soluble, active StmPr1 but failed in case of StmPr3. From laundry application tests StmPr2 turned out to be a highly wash-active protease at 45 °C. Specific activity of StmPr2 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 17 ± 2 U/mg. In addition we determined the kinetic parameters and cleavage preferences of protease StmPr2. KW - Alginate beads KW - Stenotrophomonas maltophilia KW - Detergent protease Y1 - 2012 U6 - https://doi.org/10.1016/j.jbiotec.2011.09.025 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - 157 IS - 1 SP - 140 EP - 147 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ribitsch, D. A1 - Karl, W. A1 - Birner-Gruenberger, R. A1 - Gruber, K. A1 - Eiteljoerg, I. A1 - Remler, P. A1 - Wieland, S. A1 - Siegert, Petra A1 - Maurer, Karl-Heinz A1 - Schwab, H. T1 - C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli JF - Journal of biotechnology N2 - Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7–11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease. Y1 - 2010 U6 - https://doi.org/10.1016/j.jbiotec.2010.09.947 SN - 1873-4863 (E-Journal); 0168-1656 (Print) VL - 150 IS - 3 SP - 408 EP - 416 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Vieira da Silva, Maria Eugenia A1 - Schwarzer, Klemens A1 - Hoffschmidt, Bernhard A1 - Pinheiro Rodrigues, Frederico A1 - Schwarzer, Tarik A1 - Costa Rocha, Paulo Alexandre T1 - Mass transfer correlation for evaporation–condensation thermal process in the range of 70 °C–95 °C JF - Renewable energy Y1 - 2013 SN - 1879-0682 (E-Journal); 0960-1481 (Print) VL - Vol. 53 SP - 174 EP - 179 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kusch, Peter A1 - Rieser, Claudia A1 - Knupp, Gerd A1 - Mang, Thomas T1 - Characterization of copolymers of methacrylic acid with poly(ethylene glycol) methyl ether methacrylate macromonomers by analytical pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) JF - Journal of Analytical and Applied Pyrolysis Y1 - 2015 U6 - https://doi.org/10.1016/j.jaap.2015.03.003 SN - 0165-2370 VL - Vol. 113 SP - 412 EP - 418 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dantism, S. A1 - Takenaga, S. A1 - Wagner, P. A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells JF - Procedia Engineering N2 - LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution. Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.08.647 SN - 1877-7058 N1 - Part of special issue "Eurosensors 2015" VL - 120 SP - 384 EP - 387 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Pilas, Johanna A1 - Mariano, K. A1 - Keusgen, M. A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes JF - Procedia Engineering Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.08.702 SN - 1877-7058 N1 - Part of special issue "Eurosensors 2015" VL - 120 SP - 532 EP - 535 PB - Elsevier CY - Amsterdam ER -