TY - JOUR A1 - Dienst, Karl-Jakob T1 - Bewegungsgruppen projektiv-metrischer Ebenen von Char. 2 JF - Journal für die reine und angewandte Mathematik Y1 - 1971 SN - 0075-4102 U6 - http://dx.doi.org/10.1515/crll.1971.250.130 VL - 250 SP - 130 EP - 140 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Meißen, Ralf A1 - Krischer, C. T1 - Elektronische Fernsehlesehilfe für hochgradig sehbehinderte JF - Biomedical Engineering / Biomedizinische Technik Y1 - 1978 U6 - http://dx.doi.org/10.1515/bmte.1978.23.s1.220 VL - 23 IS - s1 SP - 220 EP - 221 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Weigand, Christoph T1 - Defining Precisions for Reliable Measurement and Estimation Procedures JF - Economic Quality Control. 24 (2009), H. 1 Y1 - 2009 SN - 0940-5151 SP - 5 EP - 33 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Spillner, Jan A1 - Kopp, Rüdiger A1 - Finocchiaro, Thomas T1 - Assistierte Zirkulation : ein Überblick aus klinischer Sicht = Assisted circulation: an overview from a clinical perspective / Spillner, Jan ; Kopp, Rüdiger ; Finocchiaro, Thomas ; Behbahani, Mehdi ; Rossaint, Rolf ; Steinseifer, Ulrich ; Behr, Marek ; Au JF - Biomedizinische Technik / Biomedical Engineering. 54 (2009), H. 5 Y1 - 2009 SN - 0013-5585 N1 - Printausgabe in der Bereichsbibliothek Jülich vorhanden : 63 Z 471 SP - 255 EP - 267 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Weigand, Christoph T1 - Statistical Tests Based on Reliability and Precision JF - Economic Quality Control : EQC ; international journal for quality and reliability N2 - The construction of a statistical test is investigated which is based only on “reliability” and “precision” as quality criteria. The reliability of a statistical test is quantifiedin a straightforward way by the probability that the decision of the test is correct. However, the quantification of the precision of a statistical test is not at all evident. Thereforethe paper presents and discusses several approaches. Moreover the distinction of “nullhypothesis” and “alternative hypothesis” is not necessary any longer. Y1 - 2012 U6 - http://dx.doi.org/10.1515/eqc-2012-0002 SN - 1869-6147 VL - 27 IS - 1 SP - 43 EP - 64 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Meliß, Michael A1 - Oesterwind, Dieter A1 - Voß, Alfred T1 - Non-nuclear and non-fossil energy resources and their possibilities for future power generation JF - Kerntechnik N2 - It must be stressed that the assessment of the exploitation possibilities of the energy resources discussed in this paper requires further studies. With this proviso, the situation can be provisionally summarised as follows: The total potential of known geothermal steam sources is only 64 GW. Geothermal energy could therefore only make a significant contribution to covering the worldwide power needs if we succeed in exploiting dry geothermal reservoirs. Exploitation of tidal energy is limited to a few geographically favourable locations. The power generation potential at these locations is only about 64 GW. An important drawback of tidal power is discontinuous power generation. Large scale exploitation of wind, wave and glacier energy, and of ocean heat, requires solution of a number of technological problems. The environmental effects of exploitation of these energy resources are to some extent of a qualitatively different nature from those of operation of fossil-fuel-fired and of nuclear power plants. The scanty knowledge in this area often results in these effects being underestimated. In any case, however, it would be deliberately misleading to postulate that any form of power generation is possible without some detrimental effects on the environment. It may be stated in conclusion that, owing to their small potential or to the as yet insufficiently advanced technological development, none of the energy resources discussed in this paper can make a significant contribution to the solution of middle-term energy supply problems, i.e., to a rapid replacement of mineral oil and natural gas. Y1 - 1975 U6 - http://dx.doi.org/10.18419/opus-8093 SN - 0932-3902 N1 - Printausg. in der Bibliothek vorhanden: 63 ZS 010-1975 VL - 17 IS - 7 SP - 301 EP - 306 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Naithani, V. K A1 - Klostermeyer, Henning A1 - Lange, H. R. A1 - [u.a.], A1 - Berndt, Heinz A1 - [u.a.], T1 - Preparation of peptide derivatives for porcine proinsulin-synthesis JF - Biological Chemistry Y1 - 1971 U6 - http://dx.doi.org/10.1515/bchm2.1971.352.1.1 SN - 1437-4315 VL - 352 IS - 1 SP - 2 EP - 3 PB - De Gruyter ER - TY - JOUR A1 - Berndt, Heinz A1 - Gattner, Hans-Gregor A1 - Zahn, Helmut T1 - Semisynthetisches Des-A1-glycin-Schafinsulin JF - Biological Chemistry Y1 - 1975 U6 - http://dx.doi.org/10.1515/bchm2.1975.356.2.1455 SN - 1437-4315 VL - 356 IS - 2 SP - 1469 EP - 1472 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Frotscher, Ralf A1 - Staat, Manfred T1 - Stresses produced by different textile mesh implants in a tissue equivalent JF - BioNanoMaterials N2 - Two single-incision mini-slings used for treating urinary incontinence in women are compared with respect to the stresses they produce in their surrounding tissue. In an earlier paper we experimentally observed that these implants produce considerably different stress distributions in a muscle tissue equivalent. Here we perform 2D finite element analyses to compare the shear stresses and normal stresses in the tissue equivalent for the two meshes and to investigate their failure behavior. The results clearly show that the Gynecare TVT fails for increasing loads in a zipper-like manner because it gradually debonds from the surrounding tissue. Contrary to that, the tissue at the ends of the DynaMesh-SIS direct may rupture but only at higher loads. The simulation results are in good agreement with the experimental observations thus the computational model helps to interpret the experimental results and provides a tool for qualitative evaluation of mesh implants. Y1 - 2014 U6 - http://dx.doi.org/10.1515/bnm-2014-0003 SN - 2191-4672 (E-Journal); 2193-066X (E-Journal); 0011-8656 (Print); 1616-0177 (Print); 2193-0651 (Print) VL - 15 IS - 1-2 SP - 25 EP - 30 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Kurbel, Karl A1 - Pietsch, Wolfram ED - Kurbel, Karl ED - Mertens, Peter ED - Scheer, August W. T1 - Projektmanagementebenen bei evolutionärer Softwareentwicklung T2 - Interaktive betriebswirtschaftliche Informations- und Steuerungssysteme Y1 - 1989 SN - 3-11-012100-X U6 - http://dx.doi.org/10.1515/9783110847055-013 SP - 261 EP - 285 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Fissabre, Anke T1 - Dachterrassen der Renaissance – „Cosa più maravigliosa che gl’orti pensili di Babbilonia“ JF - Architectura : Zeitschrift für Geschichte der Baukunst Y1 - 2011 SN - 0044-863X VL - 41 IS - 1 SP - 27 EP - 46 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Kolditz, Melanie A1 - Albin, Thivaharan A1 - Brüggemann, Gert-Peter A1 - Abel, Dirk A1 - Albracht, Kirsten T1 - Robotergestütztes System für ein verbessertes neuromuskuläres Aufbautraining der Beinstrecker JF - at - Automatisierungstechnik N2 - Neuromuskuläres Aufbautraining der Beinstrecker ist ein wichtiger Bestandteil in der Rehabilitation und Prävention von Muskel-Skelett-Erkrankungen. Effektives Training erfordert hohe Muskelkräfte, die gleichzeitig hohe Belastungen von bereits geschädigten Strukturen bedeuten. Um trainingsinduzierte Schädigungen zu vermeiden, müssen diese Kräfte kontrolliert werden. Mit heutigen Trainingsgeräten können diese Ziele allerdings nicht erreicht werden. Für ein sicheres und effektives Training sollen durch den Einsatz der Robotik, Sensorik, eines Regelkreises sowie Muskel-Skelett-Modellen Belastungen am Zielgewebe direkt berechnet und kontrolliert werden. Auf Basis zweier Vorstudien zu möglichen Stellgrößen wird der Aufbau eines robotischen Systems vorgestellt, das sowohl für Forschungszwecke als auch zur Entwicklung neuartiger Trainingsgeräte verwendet werden kann. Y1 - 2016 U6 - http://dx.doi.org/10.1515/auto-2016-0044 SN - 2196-677X VL - 64 IS - 11 SP - 905 EP - 914 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Poth, Sebastian A1 - Monzon, Magaly A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Lignocellulosic biorefinery: Process integration of hydrolysis and fermentation (SSF process) JF - Holzforschung N2 - The aim of the present work is the process integration and the optimization of the enzymatic hydrolysis of wood and the following fermentation of the products to ethanol. The substrate is a fiber fraction obtained by organosolv pre-treatment of beech wood. For the ethanol production, a co-fermentation by two different yeasts (Saccharomyces cerevisiae and Pachysolen tannophilus) was carried out to convert glucose as well as xylose. Two approaches has been followed: 1. A two step process, in which the hydrolysis of the fiber fraction and the fermentation to product are separated from each other. 2. A process, in which the hydrolysis and the fermentation are carried out in one single process step as simultaneous saccharification and fermentation (SSF). Following the first approach, a yield of about 0.15 g ethanol per gram substrate can be reached. Based on the SSF, one process step can be saved, and additionally, the gained yield can be raised up to 0.3 g ethanol per gram substrate. Y1 - 2011 N1 - 11th EWLP, Hamburg, Germany, August 16–19, 2010 VL - 65 IS - 5 SP - 633 EP - 637 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors T1 - Markierungsfreie Detektion doppelsträngiger DNA Moleküle mit Hilfe von Polyelektrolyt-modifizierten kapazitiven Feldeffekt-Sensoren JF - tm - Technisches Messen N2 - In this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA)molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto theSiO2-chip surface.EIS sensors can be utilized as a tool to detect surface-charge changes; the electrostatic adsorption of oligonucleotides onto the polyelectrolyte layer leads to a measureable surface-potential change. Signals of 39mV have been recorded after the incubation with the oligonucleotide solution. Besides the electrochemical experiments, the successful adsorption of dsDNA onto the polyelectrolyte layer has been verified via fluorescence microscopy. The presented results demonstrate that the signal recording of EISchips, which are modified with a polyelectrolyte layer, canbe used as a favorable approach for a fast, cheap and simple detection method for dsDNA. Y1 - 2017 U6 - http://dx.doi.org/10.1515/teme-2017-0015 VL - 84 IS - 10 SP - 628 EP - 634 PB - De Gruyter CY - Oldenbourg ER - TY - JOUR A1 - Tran, Linda A1 - Mottaghy, K. A1 - Arlt-Körfer, Sabine A1 - Waluga, Christian A1 - Behbahani, Mehdi T1 - An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system JF - Biomedizinische Technik Y1 - 2017 U6 - http://dx.doi.org/10.1515/bmt-2015-0034 SN - 0013-5585 VL - 62 IS - 4 SP - 383 EP - 392 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Bhattarai, Aroj A1 - Jabbari, Medisa A1 - Anding, Ralf A1 - Staat, Manfred T1 - Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis JF - tm - Technisches Messen N2 - Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores. Insbesondere ältere, mehrgebährende Frauen leiden häufiger an einem Scheidenvorfall nach einer Hysterektomie aufgrund der schwachen Unterstützung durch laxe apikale Bänder. Es wird angenommen, dass eine verringerte Menge an Östrogen und Progesteron im höheren Alter das Kollagen umformt, wodurch die Gewebesteifigkeit reduziert wird. Die Sakrokolpopexie ist eine offene oder laparoskopische Operation, die mit prothetischen Netzimplantaten durchgeführt wird, um laxe Bänder zu ersetzen. Y-förmige Netzmodelle (DynaMesh, Gynemesh und Ultrapro) werden in einem 3D-Modell des weiblichen Beckenbodens im extraperitonealen Raum vom Vaginalstumpf bis zum Promontorium implantiert. Numerische Simulationen werden während des Valsalva-Manövers mit geschwächtem Gewebe durchgeführt, das durch eine reduzierte Gewebesteifigkeit modelliert wird. Die Gewebe werden als inkompressible, isotrop hyperelastische Materialien modelliert, während die Netze entweder als orthotrope linear elastische oder als isotrope hyperlastische Materialien modelliert werden. Die Positionen des Vaginalstumpfs, der Blase und der Harnröhrenachse werden anhand der Pubococcygeallinie aus der Ruhelage, für den Prolaps und nach der Reparatur unter Verwendung der drei Netze berechnet. Aufgrund der Netzmechanik und der Netzporenverformung bietet das DynaMesh mit regelmäßigen rechteckigen Netzporen eine bessere mechanische Unterstützung und eine Neupositionierung des Scheidengewölbes, der Blase und der Urethraachse als Gynemesh und Ultrapro mit unregelmäßigen hexagonalen Netzporen. Y1 - 2018 U6 - http://dx.doi.org/10.1515/teme-2017-0115 SN - 2196-7113 VL - 85 IS - 5 SP - 331 EP - 342 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Birgel, Stefan A1 - Leschinger, Tim A1 - Wegmann, Kilian A1 - Staat, Manfred T1 - Calculation of muscle forces and joint reaction loads in the shoulder area via an OpenSim based computer model JF - tm - Technisches Messen N2 - Using the OpenSim software and verified anatomical data, a computer model for the calculation of biomechanical parameters is developed and used to determine the effect of a reattachment of the Supraspinatus muscle with a medial displacement of the muscle attachment point, which may be necessary for a rupture of the supraspinatus tendon. The results include the influence of the operation on basic biomechanical parameters such as the lever arm, as well as the calculated the muscle activations for the supraspinatus and deltoid. In addition, the influence on joint stability is examined by an analysis of the joint reaction force. The study provides a detailed description of the used model, as well as medical findings to a reattachment of the supraspinatus. Mit der Software OpenSim und überprüften anatomischen Daten wird ein Computermodell zur Berechnung von biomechanischen Parametern entwickelt und genutzt, um den Effekt einer Refixierung des Supraspinatusmuskels mit einer medialen Verschiebung des Muskelansatzpunktes zu ermitteln, wie sie unter anderem nach einem Riss der Supraspinatussehne notwendig sein kann. Die Ergebnisse umfassen hierbei den Einfluss der Operation auf grundlegende biomechanische Parameter wie den Hebelarm sowie die berechneten Muskelaktivierungen für den Supraspinatus und Deltoideus. Zusätzlich wird der Einfluss auf die Gelenkstabilität betrachtet und durch eine Analyse der Gelenkreaktionskraft untersucht. Die Studie bietet eine detaillierte Beschreibung des genutzten Modells, sowie medizinische Erkenntnisse zu einer Refixierung des Supraspinatus. Y1 - 2018 U6 - http://dx.doi.org/10.1515/teme-2017-0114 SN - 2196-7113 VL - 85 IS - 5 SP - 321 EP - 330 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Wilke, Thomas T1 - Peyre, Marie-Josephe T2 - Allgemeines Künstler-Lexikon. Bd. 95 Y1 - 2017 SN - 978-3-11-023261-5 N1 - namentlich gekennzeichneter Lexikon-Eintrag SP - 301 EP - 302 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Wilke, Thomas T1 - Peyre, Antoine-Francois T2 - Allgemeines Künstler-Lexikon. Bd. 95 Y1 - 2017 SN - 978-3-11-023261-5 N1 - namentlich gekennzeichneter Lexikon-Eintrag SP - 300 EP - 301 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Wilke, Thomas T1 - Patte, Pierre T2 - Allgemeines Künstler-Lexikon. Bd. 94 Y1 - 2017 SN - 978-3-11-023260-8 N1 - namentlich gekennzeichneter Lexikon-Eintrag SP - 429 EP - 430 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Wilke, Thomas T1 - Ranson, Pierre T2 - Allgemeines Künstler-Lexikon. Online Y1 - 2017 N1 - namentlich gekennzeichneter Lexikon-Eintrag PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Wilke, Thomas T1 - Lepautre T2 - Allgemeines Künstler-Lexikon. Bd. 84 Y1 - 2015 SN - 978-3-11-023189-2 N1 - unter besonderer Berücksichtigung von Antoine, Jean und Pierre Lepautre; namentlich gekennzeichneter Lexikon-Eintrag SP - 157 EP - 160 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Horbach, Andreas A1 - Staat, Manfred T1 - Optical strain measurement for the modeling of surgical meshes and their porosity JF - Current Directions in Biomedical Engineering N2 - The porosity of surgical meshes makes them flexible for large elastic deformation and establishes the healing conditions of good tissue in growth. The biomechanic modeling of orthotropic and compressible materials requires new materials models and simulstaneoaus fit of deformation in the load direction as well as trannsversely to to load. This nonlinear modeling can be achieved by an optical deformation measurement. At the same time the full field deformation measurement allows the dermination of the change of porosity with deformation. Also the socalled effective porosity, which has been defined to asses the tisssue interatcion with the mesh implants, can be determined from the global deformation of the surgical meshes. Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0045 SN - 2364-5504 VL - Band 4 IS - 1 SP - 181 EP - 184 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Bhattarai, Aroj A1 - Staat, Manfred T1 - Computational comparison of different textile implants to correct apical prolapse in females JF - Current Directions in Biomedical Engineering N2 - Prosthetic textile implants of different shapes, sizes and polymers are used to correct the apical prolapse after hysterectomy (removal of the uterus). The selection of the implant before or during minimally invasive surgery depends on the patient’s anatomical defect, intended function after reconstruction and most importantly the surgeon’s preference. Weakness or damage of the supporting tissues during childbirth, menopause or previous pelvic surgeries may put females in higher risk of prolapse. Numerical simulations of reconstructed pelvic floor with weakened tissues and organ supported by textile product models: DynaMesh®-PRS soft, DynaMesh®-PRP soft and DynaMesh®-CESA from FEG Textiletechnik mbH, Germany are compared. Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0159 VL - 4 IS - 1 SP - 661 EP - 664 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Lapitan, Denis G. A1 - Rogatkin, Dmitrii A. A1 - Persheyev, Sydulla K. A1 - Kotliar, Konstantin T1 - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter JF - Biomedizinische Technik N2 - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise. Y1 - 2018 U6 - http://dx.doi.org/10.1515/bmt-2017-0060 SN - 0013-5585 VL - 63 IS - 4 SP - 439 EP - 444 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Kampker, Achim A1 - Schleser, Markus A1 - Triebs, Johannes A1 - Berg, Alexander-Karl A1 - Hansen, Jan Ole A1 - Fiedler, Falko T1 - Bauteilintegrierte Vorrichtungsfunktionen im Karosseriebau : Aktuelle Ergebnisse im Forschungsprojekt ProeK JF - ZWF Zeitschrift für wirtschaftlichen Fabrikbetrieb N2 - Das Forschungsprojekt Produktionseffizienz in der Kleinserie (ProeK) erarbeitet kostengünstige und effiziente Lösungsansätze für Prozessketten im Zukunftsfeld der Elektromobilität. Das Teilprojekt Karosserie setzt diese Zielsetzung durch innovative und praxisorientierte Produkt- und Prozesskonzepte mit neuartigen bauteilintegrierten Vorrichtungsfunktionen (BiV) um. Im Teilprojekt Außenhaut sollen Toleranzen adaptiv durch Anpassungen der Prozessparameter sowie Bauteilmanipulation kompensiert werden. Y1 - 2018 U6 - http://dx.doi.org/10.3139/104.112012 SN - 0947-0085 VL - 113 IS - 11 SP - 767 EP - 770 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin A1 - Ramser, Claudia T1 - Grenzenlose Liebe T2 - Examensklausurenkurs : 16 Examensklausuren mit ausformulierten Lösungen ; zahlreiche Originalexamensklausuren ; Zivilrecht, Strafrecht, öffentliches Recht, Schwerpunktbereiche Y1 - 2008 SN - 978-3-89949-455-6 N1 - Jura Sonderheft SP - 51 EP - 56 PB - de Gruyter Recht CY - Berlin ER - TY - JOUR A1 - Laura, C.O. A1 - Drechsler, Klaus A1 - Erdt, M. A1 - Wesarg, S. A1 - Bale, R. T1 - Intervention assessment tool for primary tumors in the liver JF - Current Directions in Biomedical Engineering N2 - After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm. Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0081 SN - 2364-5504 VL - 4 IS - 1 SP - 337 EP - 340 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Buhl, Eva Miriam A1 - Baumann, Martin A1 - Schmitz-Rode, Thomas A1 - Slabu, Ioana T1 - Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia JF - Current Directions in Biomedical Engineering Y1 - 2017 U6 - http://dx.doi.org/10.1515/cdbme-2017-0096 SN - 2364-5504 VL - 3 IS - 2 SP - 457 EP - 460 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Grundlach, Michael A1 - Baumann, Martin A1 - Engelmann, Ulrich M. ED - Dössel, Olaf T1 - How Multimodal Examinations Can Increase Sustainable Student Gain by Aligning Teaching and Assessment JF - Current Directions in Biomedical Engineering N2 - Modern industry and multi-discipline projects require highly trained individuals with resilient science and engineering back-grounds. Graduates must be able to agilely apply excellent theoretical knowledge in their subject matter as well as essential practical “hands-on” knowledge of diverse working processes to solve complex problems. To meet these demands, university education follows the concept of Constructive Alignment and thus increasingly adopts the teaching of necessary practical skills to the actual industry requirements and assessment routines. However, a systematic approach to coherently align these three central teaching demands is strangely absent from current university curricula. We demonstrate the feasibility of implementing practical assessments in a regular theory-based examination, thus defining the term “blended assessment”. We assessed a course for natural science and engineering students pursuing a career in biomedical engineering, and evaluated the benefit of blended assessment exams for students and lecturers. Our controlled study assessed the physiological background of electrocardiograms (ECGs), the practical measurement of ECG curves, and their interpretation of basic pathologic alterations. To study on long time effects, students have been assessed on the topic twice with a time lag of 6 months. Our findings suggest a significant improvement in student gain with respect to practical skills and theoretical knowledge. The results of the reassessments support these outcomes. From the lecturers ́ point of view, blended assessment complements practical training courses while keeping organizational effort manageable. We consider blended assessment a viable tool for providing an improved student gain, industry-ready education format that should be evaluated and established further to prepare university graduates optimally for their future careers. KW - constructive alignment KW - examination KW - long-term retention KW - multimodal KW - practical learning Y1 - 2021 SN - 2364-5504 U6 - http://dx.doi.org/10.1515/cdbme-2021-2019 VL - 7 IS - 7/2 SP - 73 EP - 76 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Gazda, Quentin A1 - Maurischat, Andreas T1 - Special functions and Gauss-Thakur sums in higher rank and dimension Y1 - 2020 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Czarnecki, Christian A1 - Fettke, Peter ED - Czarnecki, Christian ED - Fettke, Peter T1 - Robotic process automation : Positioning, structuring, and framing the work T2 - Robotic process automation : Management, technology, applications N2 - Robotic process automation (RPA) has attracted increasing attention in research and practice. This chapter positions, structures, and frames the topic as an introduction to this book. RPA is understood as a broad concept that comprises a variety of concrete solutions. From a management perspective RPA offers an innovative approach for realizing automation potentials, whereas from a technical perspective the implementation based on software products and the impact of artificial intelligence (AI) and machine learning (ML) are relevant. RPA is industry-independent and can be used, for example, in finance, telecommunications, and the public sector. With respect to RPA this chapter discusses definitions, related approaches, a structuring framework, a research framework, and an inside as well as outside architectural view. Furthermore, it provides an overview of the book combined with short summaries of each chapter. KW - Robotic process automation KW - management KW - technology KW - applications KW - research framework Y1 - 2021 SN - 978-3-11-067668-6 (Print) SN - 978-3-11-067669-3 (PDF) SN - 978-3-11-067677-8 (ePub) U6 - http://dx.doi.org/10.1515/9783110676693-202 SP - 3 EP - 24 PB - De Gruyter CY - Oldenbourg ER - TY - CHAP A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian ED - Czarnecki, Christian ED - Fettke, Peter T1 - Finding the perfect RPA match : a criteria-based selection method for RPA solutions T2 - Robotic process automation : Management, technology, applications N2 - The benefits of robotic process automation (RPA) are highly related to the usage of commercial off-the-shelf (COTS) software products that can be easily implemented and customized by business units. But, how to find the best fitting RPA product for a specific situation that creates the expected benefits? This question is related to the general area of software evaluation and selection. In the face of more than 75 RPA products currently on the market, guidance considering those specifics is required. Therefore, this chapter proposes a criteria-based selection method specifically for RPA. The method includes a quantitative evaluation of costs and benefits as well as a qualitative utility analysis based on functional criteria. By using the visualization of financial implications (VOFI) method, an application-oriented structure is provided that opposes the total cost of ownership to the time savings times salary (TSTS). For the utility analysis a detailed list of functional criteria for RPA is offered. The whole method is based on a multi-vocal review of scientific and non-scholarly literature including publications by business practitioners, consultants, and vendors. The application of the method is illustrated by a concrete RPA example. The illustrated structures, templates, and criteria can be directly utilized by practitioners in their real-life RPA implementations. In addition, a normative decision process for selecting RPA alternatives is proposed before the chapter closes with a discussion and outlook. KW - robotic process automation KW - business process automation KW - commercial offthe- shelf solutions KW - software evaluation KW - software selection Y1 - 2021 SN - 978-3-11-067677-8 SN - 978-3-11-067669-3 SN - 9783110676686 U6 - http://dx.doi.org/10.1515/9783110676693-201 SP - 47 EP - 75 PB - De Gruyter CY - Oldenbourg ER - TY - CHAP A1 - Croon, Philipp A1 - Czarnecki, Christian ED - Czarnecki, Christian ED - Fettke, Peter T1 - Liability for loss or damages caused by RPA T2 - Robotic process automation : Management, technology, applications N2 - Intelligent autonomous software robots replacing human activities and performing administrative processes are reality in today’s corporate world. This includes, for example, decisions about invoice payments, identification of customers for a marketing campaign, and answering customer complaints. What happens if such a software robot causes a damage? Due to the complete absence of human activities, the question is not trivial. It could even happen that no one is liable for a damage towards a third party, which could create an uncalculatable legal risk for business partners. Furthermore, the implementation and operation of those software robots involves various stakeholders, which result in the unsolvable endeavor of identifying the originator of a damage. Overall it is advisable to all involved parties to carefully consider the legal situation. This chapter discusses the liability of software robots from an interdisciplinary perspective. Based on different technical scenarios the legal aspects of liability are discussed. KW - robotic process automation KW - artificial intelligence KW - liability KW - culpability Y1 - 2021 SN - 9783110676778 SN - 9783110676693 SN - 9783110676686 U6 - http://dx.doi.org/10.1515/9783110676693-202 SP - 135 EP - 151 PB - De Gruyter CY - Oldenbourg ER - TY - JOUR A1 - Ketelhut, Maike A1 - Göll, Fabian A1 - Braunstein, Björn A1 - Albracht, Kirsten A1 - Abel, Dirk T1 - Comparison of different training algorithms for the leg extension training with an industrial robot JF - Current Directions in Biomedical Engineering N2 - In the past, different training scenarios have been developed and implemented on robotic research platforms, but no systematic analysis and comparison have been done so far. This paper deals with the comparison of an isokinematic (motion with constant velocity) and an isotonic (motion against constant weight) training algorithm. Both algorithms are designed for a robotic research platform consisting of a 3D force plate and a high payload industrial robot, which allows leg extension training with arbitrary six-dimensional motion trajectories. In the isokinematic as well as the isotonic training algorithm, individual paths are defined i n C artesian s pace by sufficient s upport p oses. I n t he i sotonic t raining s cenario, the trajectory is adapted to the measured force as the robot should only move along the trajectory as long as the force applied by the user exceeds a minimum threshold. In the isotonic training scenario however, the robot’s acceleration is a function of the force applied by the user. To validate these findings, a simulative experiment with a simple linear trajectory is performed. For this purpose, the same force path is applied in both training scenarios. The results illustrate that the algorithms differ in the force dependent trajectory adaption. KW - Rehabilitation Technology and Prosthetics KW - Surgical Navigation and Robotics Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0005 SN - 2364-5504 VL - 4 IS - 1 SP - 17 EP - 20 PB - De Gruyter CY - Berlin ER -