TY - CHAP A1 - Duong, Minh Tuan A1 - Seifarth, Volker A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Staat, Manfred ED - Artmann, Gerhard ED - Temiz Artmann, Aysegül ED - Zhubanova, Azhar A. ED - Digel, Ilya T1 - Growth Modelling Promoting Mechanical Stimulation of Smooth Muscle Cells of Porcine Tubular Organs in a Fibrin-PVDF Scaffold T2 - Biological, Physical and Technical Basics of Cell Engineering N2 - Reconstructive surgery and tissue replacements like ureters or bladders reconstruction have been recently studied, taking into account growth and remodelling of cells since living cells are capable of growing, adapting, remodelling or degrading and restoring in order to deform and respond to stimuli. Hence, shapes of ureters or bladders and their microstructure change during growth and these changes strongly depend on external stimuli such as training. We present the mechanical stimulation of smooth muscle cells in a tubular fibrin-PVDFA scaffold and the modelling of the growth of tissue by stimuli. To this end, mechanotransduction was performed with a kyphoplasty balloon catheter that was guided through the lumen of the tubular structure. The bursting pressure was examined to compare the stability of the incubated tissue constructs. The results showed the significant changes on tissues with training by increasing the burst pressure as a characteristic mechanical property and the smooth muscle cells were more oriented with uniformly higher density. Besides, the computational growth models also exhibited the accurate tendencies of growth of the cells under different external stimuli. Such models may lead to design standards for the better layered tissue structure in reconstructing of tubular organs characterized as composite materials such as intestines, ureters and arteries. KW - Mechanical simulation KW - Growth modelling KW - Ureter KW - Bladder KW - Reconstruction Y1 - 2018 SN - 978-981-10-7904-7 U6 - https://doi.org/10.1007/978-981-10-7904-7_9 SP - 209 EP - 232 PB - Springer CY - Singapore ER - TY - JOUR A1 - Hackl, Michael A1 - Müller, Lars-Peter A1 - Staat, Manfred A1 - Kahmann, Stephanie Lucina A1 - Wegmann, Kilian T1 - Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques JF - Knee surgery, sports traumatology, arthroscopy N2 - Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis. Y1 - 2016 U6 - https://doi.org/10.1007/s00167-016-4080-7 SN - 0942-2056 VL - Volume 24 IS - Supplement 1 SP - 148 EP - 149 PB - Springer CY - Berlin ER - TY - JOUR A1 - Dietzel, F. A1 - Weber, Hans-Joachim A1 - Porschen, W. A1 - Feinendegen, L. E. T1 - Zur Wärmeempfindlichkeit von oxischen und hypoxischen Zellen in einem Tumor JF - Naturwissenschaften Y1 - 1976 U6 - https://doi.org/10.1007/BF00622808 SN - 0028-1042 VL - 63 IS - 12 SP - 585 EP - 586 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel A1 - Thiele, Jan Philipp T1 - Statistical inference for L²-distances to uniformity JF - Computational Statistics N2 - The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study. KW - Integrated empirical distribution (survival) function KW - Goodness-of-fit tests for uniformity KW - Numerical inversion of Laplace transforms KW - Coverage probability KW - Equivalence test Y1 - 2018 U6 - https://doi.org/10.1007/s00180-018-0820-0 SN - 1613-9658 VL - 2018 IS - 33 SP - 1863 EP - 1896 PB - Springer CY - Berlin ER - TY - JOUR A1 - Gaigall, Daniel T1 - Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data JF - Metrika N2 - We discuss the testing problem of homogeneity of the marginal distributions of a continuous bivariate distribution based on a paired sample with possibly missing components (missing completely at random). Applying the well-known two-sample Crámer–von-Mises distance to the remaining data, we determine the limiting null distribution of our test statistic in this situation. It is seen that a new resampling approach is appropriate for the approximation of the unknown null distribution. We prove that the resulting test asymptotically reaches the significance level and is consistent. Properties of the test under local alternatives are pointed out as well. Simulations investigate the quality of the approximation and the power of the new approach in the finite sample case. As an illustration we apply the test to real data sets. KW - Marginal homogeneity test KW - Crámer–von-Mises distance KW - Paired sample KW - Incomplete data KW - Resampling test Y1 - 2019 U6 - https://doi.org/10.1007/s00184-019-00742-5 SN - 1435-926X VL - 2020 IS - 83 SP - 437 EP - 465 PB - Springer ER - TY - JOUR A1 - Ditzhaus, Marc A1 - Gaigall, Daniel T1 - Testing marginal homogeneity in Hilbert spaces with applications to stock market returns JF - Test N2 - This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cramér–von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices. Y1 - 2022 U6 - https://doi.org/10.1007/s11749-022-00802-5 SN - 1863-8260 VL - 2022 IS - 31 SP - 749 EP - 770 PB - Springer ER - TY - JOUR A1 - Duong, Minh Tuan A1 - Nguyen, Nhu Huynh A1 - Staat, Manfred T1 - Physical response of hyperelastic models for composite materials and soft tissues JF - Asia pacific journal on computational engineering Y1 - 2015 U6 - https://doi.org/10.1186/s40540-015-0015-x SN - 2196-1166 VL - 2 IS - 3 (December 2015) SP - 1 EP - 18 ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 71 EP - 87 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Kleefeld, Andreas T1 - The hot spots conjecture can be false: some numerical examples JF - Advances in Computational Mathematics N2 - The hot spots conjecture is only known to be true for special geometries. This paper shows numerically that the hot spots conjecture can fail to be true for easy to construct bounded domains with one hole. The underlying eigenvalue problem for the Laplace equation with Neumann boundary condition is solved with boundary integral equations yielding a non-linear eigenvalue problem. Its discretization via the boundary element collocation method in combination with the algorithm by Beyn yields highly accurate results both for the first non-zero eigenvalue and its corresponding eigenfunction which is due to superconvergence. Additionally, it can be shown numerically that the ratio between the maximal/minimal value inside the domain and its maximal/minimal value on the boundary can be larger than 1 + 10− 3. Finally, numerical examples for easy to construct domains with up to five holes are provided which fail the hot spots conjecture as well. KW - Numerics KW - Boundary integral equations KW - Potential theory KW - Helmholtz equation KW - Interior Neumann eigenvalues Y1 - 2021 U6 - https://doi.org/10.1007/s10444-021-09911-5 SN - 1019-7168 VL - 47 PB - Springer CY - Dordrecht ER - TY - CHAP A1 - Kahra, Marvin A1 - Breuß, Michael A1 - Kleefeld, Andreas A1 - Welk, Martin ED - Brunetti, Sara ED - Frosini, Andrea ED - Rinaldi, Simone T1 - An Approach to Colour Morphological Supremum Formation Using the LogSumExp Approximation T2 - Discrete Geometry and Mathematical Morphology N2 - Mathematical morphology is a part of image processing that has proven to be fruitful for numerous applications. Two main operations in mathematical morphology are dilation and erosion. These are based on the construction of a supremum or infimum with respect to an order over the tonal range in a certain section of the image. The tonal ordering can easily be realised in grey-scale morphology, and some morphological methods have been proposed for colour morphology. However, all of these have certain limitations. In this paper we present a novel approach to colour morphology extending upon previous work in the field based on the Loewner order. We propose to consider an approximation of the supremum by means of a log-sum exponentiation introduced by Maslov. We apply this to the embedding of an RGB image in a field of symmetric 2x2 matrices. In this way we obtain nearly isotropic matrices representing colours and the structural advantage of transitivity. In numerical experiments we highlight some remarkable properties of the proposed approach. Y1 - 2024 SN - 978-3-031-57793-2 U6 - https://doi.org/10.1007/978-3-031-57793-2_25 N1 - Third International Joint Conference, DGMM 2024, Florence, Italy, April 15–18, 2024 SP - 325 EP - 337 PB - Springer CY - Cham ER - TY - JOUR A1 - Schneider, Jules A1 - Schwabedal, Justus T. C. A1 - Bialonski, Stephan T1 - Schlafspindeln – Funktion, Detektion und Nutzung als Biomarker für die psychiatrische Diagnostik JF - Der Nervenarzt N2 - Hintergrund: Die Schlafspindel ist ein Graphoelement des Elektroenzephalogramms (EEG), das im Leicht- und Tiefschlaf beobachtet werden kann. Veränderungen der Spindelaktivität wurden für verschiedene psychiatrische Erkrankungen beschrieben. Schlafspindeln zeigen aufgrund ihrer relativ konstanten Eigenschaften Potenzial als Biomarker in der psychiatrischen Diagnostik. Methode: Dieser Beitrag liefert einen Überblick über den Stand der Wissenschaft zu Eigenschaften und Funktionen der Schlafspindeln sowie über beschriebene Veränderungen der Spindelaktivität bei psychiatrischen Erkrankungen. Verschiedene methodische Ansätze und Ausblicke zur Spindeldetektion werden hinsichtlich deren Anwendungspotenzial in der psychiatrischen Diagnostik erläutert. Ergebnisse und Schlussfolgerung: Während Veränderungen der Spindelaktivität bei psychiatrischen Erkrankungen beschrieben wurden, ist deren exaktes Potenzial für die psychiatrische Diagnostik noch nicht ausreichend erforscht. Diesbezüglicher Erkenntnisgewinn wird in der Forschung gegenwärtig durch ressourcenintensive und fehleranfällige Methoden zur manuellen oder automatisierten Spindeldetektion ausgebremst. Neuere Detektionsansätze, die auf Deep-Learning-Verfahren basieren, könnten die Schwierigkeiten bisheriger Detektionsmethoden überwinden und damit neue Möglichkeiten für die praktisch KW - Schlafspindeldetektion KW - Psychiatrische Biomarker KW - · Psychiatrische Erkrankungen/Diagnostik KW - Elektroenzephalographie KW - Deep Learning Y1 - 2022 U6 - https://doi.org/10.1007/s00115-022-01340-z SN - 1433-0407 SP - 1 EP - 8 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Hafner, David A1 - Demetz, Oliver A1 - Weickert, Joachim A1 - Reißel, Martin T1 - Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation JF - Journal of Mathematical Imaging and Vision Y1 - 2014 U6 - https://doi.org/10.1007/s10851-014-0529-9 SN - 1573-7683 (Online) N1 - Springer Online First (ohne Seitenang. und Heftzuteilung) PB - Springer CY - New York ER - TY - JOUR A1 - Kohl, Philipp A1 - Krämer, Yoka A1 - Fohry, Claudia A1 - Kraft, Bodo ED - Fred, Ana ED - Hadjali, Allel ED - Gusikhin, Oleg ED - Sansone, Carlo T1 - Scoping review of active learning strategies and their evaluation environments for entity recognition tasks JF - Deep learning theory and applications N2 - We conducted a scoping review for active learning in the domain of natural language processing (NLP), which we summarize in accordance with the PRISMA-ScR guidelines as follows: Objective: Identify active learning strategies that were proposed for entity recognition and their evaluation environments (datasets, metrics, hardware, execution time). Design: We used Scopus and ACM as our search engines. We compared the results with two literature surveys to assess the search quality. We included peer-reviewed English publications introducing or comparing active learning strategies for entity recognition. Results: We analyzed 62 relevant papers and identified 106 active learning strategies. We grouped them into three categories: exploitation-based (60x), exploration-based (14x), and hybrid strategies (32x). We found that all studies used the F1-score as an evaluation metric. Information about hardware (6x) and execution time (13x) was only occasionally included. The 62 papers used 57 different datasets to evaluate their respective strategies. Most datasets contained newspaper articles or biomedical/medical data. Our analysis revealed that 26 out of 57 datasets are publicly accessible. Conclusion: Numerous active learning strategies have been identified, along with significant open questions that still need to be addressed. Researchers and practitioners face difficulties when making data-driven decisions about which active learning strategy to adopt. Conducting comprehensive empirical comparisons using the evaluation environment proposed in this study could help establish best practices in the domain. Y1 - 2024 SN - 978-3-031-66694-0 (online ISBN) SN - 978-3-031-66693-3 (print ISBN) U6 - https://doi.org/10.1007/978-3-031-66694-0_6 SP - 84 EP - 106 PB - Springer CY - Cham ER - TY - CHAP A1 - Maurer, Florian A1 - Miskiw, Kim K. A1 - Acosta, Rebeca Ramirez A1 - Harder, Nick A1 - Sander, Volker A1 - Lehnhoff, Sebastian ED - Jorgensen, Bo Norregaard ED - Pereira da Silva, Luiz Carlos ED - Ma, Zheng T1 - Market abstraction of energy markets and policies - application in an agent-based modeling toolbox T2 - EI.A 2023: Energy Informatics N2 - In light of emerging challenges in energy systems, markets are prone to changing dynamics and market design. Simulation models are commonly used to understand the changing dynamics of future electricity markets. However, existing market models were often created with specific use cases in mind, which limits their flexibility and usability. This can impose challenges for using a single model to compare different market designs. This paper introduces a new method of defining market designs for energy market simulations. The proposed concept makes it easy to incorporate different market designs into electricity market models by using relevant parameters derived from analyzing existing simulation tools, morphological categorization and ontologies. These parameters are then used to derive a market abstraction and integrate it into an agent-based simulation framework, allowing for a unified analysis of diverse market designs. Furthermore, we showcase the usability of integrating new types of long-term contracts and over-the-counter trading. To validate this approach, two case studies are demonstrated: a pay-as-clear market and a pay-as-bid long-term market. These examples demonstrate the capabilities of the proposed framework. KW - Energy market design KW - Agent-based simulation KW - Market modeling Y1 - 2023 SN - 978-3-031-48651-7 (Print) SN - 978-3-031-48652-4 (eBook) U6 - https://doi.org/10.1007/978-3-031-48652-4_10 N1 - Third Energy Informatics Academy Conference, EI.A 2023, Campinas, Brazil, December 6–8, 2023 N1 - Part of the Lecture Notes in Computer Science book series (LNCS,volume 14468). SP - 139 EP - 157 PB - Springer CY - Cham ER - TY - JOUR A1 - Belavy, Daniel L. A1 - Albracht, Kirsten A1 - Brüggemann, Gert-Peter A1 - Vergroesen, Pieter-Paul A. A1 - Dieen, Jaap H. van T1 - Can exercise positively influence the intervertebral disc? JF - Sports Medicine N2 - To better understand what kinds of sports and exercise could be beneficial for the intervertebral disc (IVD), we performed a review to synthesise the literature on IVD adaptation with loading and exercise. The state of the literature did not permit a systematic review; therefore, we performed a narrative review. The majority of the available data come from cell or whole-disc loading models and animal exercise models. However, some studies have examined the impact of specific sports on IVD degeneration in humans and acute exercise on disc size. Based on the data available in the literature, loading types that are likely beneficial to the IVD are dynamic, axial, at slow to moderate movement speeds, and of a magnitude experienced in walking and jogging. Static loading, torsional loading, flexion with compression, rapid loading, high-impact loading and explosive tasks are likely detrimental for the IVD. Reduced physical activity and disuse appear to be detrimental for the IVD. We also consider the impact of genetics and the likelihood of a ‘critical period’ for the effect of exercise in IVD development. The current review summarises the literature to increase awareness amongst exercise, rehabilitation and ergonomic professionals regarding IVD health and provides recommendations on future directions in research. KW - Intradiscal Pressure KW - Annulus Fibrosus KW - Disc Degeneration KW - Nucleus Pulposus KW - Intervertebral Disc Y1 - 2016 U6 - https://doi.org/10.1007/s40279-015-0444-2 SN - 1179-2035 VL - 46 IS - 4 SP - 473 EP - 485 PB - Springer CY - Berlin ER - TY - JOUR A1 - Berretz, Frank A1 - Skorupa, Sascha A1 - Sander, Volker A1 - Belloum, Adam A1 - Bubak, Marian T1 - Actor-Driven Workflow Execution in Distributed Environments JF - Euro-Par 2010 Parallel Processing Workshops : HeteroPAR, HPCC, HiBB, CoreGrid, UCHPC, HPCF, PROPER, CCPI, VHPC ; Ischia, Italy, August 31 - September 3, 2010 ; revised selected papers / Mario R. Guarracino ... (eds.) Y1 - 2011 SN - 978-3-642-21877-4 N1 - Lecture Notes in Computer Science ; 6586 SP - 287 EP - 294 PB - Springer CY - Berlin ER -