TY - CHAP A1 - Digel, Ilya A1 - Demirci, Taylan A1 - Trzewik, Jürgen A1 - Linder, Peter A1 - Temiz Artmann, Aysegül T1 - Fibroblast response to mechanical stress: role of the adhesion substrate : [abstract] N2 - Mechanical stimulation of the cells resulted in evident changes in the cell morphology, protein composition and gene expression. Microscopically, additional formation of stress fibers accompanied by cell re-arrangements in a monolayer was observed. Also, significant activation of p53 gene was revealed as compared to control. Interestingly, the use of CellTech membrane coating induced cell death after mechanical stress had been applied. Such an effect was not detected when fibronectin had been used as an adhesion substrate. KW - Fibroblast KW - Mechanische Beanspruchung KW - celldrum technology Y1 - 2004 ER - TY - CHAP A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Nojima, H. A1 - Artmann, Gerhard T1 - Effects of plasma generated ions on bacteria : [poster] N2 - Summary and Conclusions PCIs were clearly effective in terms of their antibacterial effects with the strains tested. This efficacy increased with the time the bacteries were exposed to PCIs. The bactericidal action has proved to be irreversible. PCIs were significantly less effective in shadowed areas. PCI exposure caused multiple protein damages as observed in SDS PAGE studies. There was no single but multiple molecular mechanism causing the bacterial death. KW - Clusterion KW - Bakterien KW - plasma generated ions Y1 - 2003 ER -