TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Razzaque, Mohammed S. T1 - Role of vitamins in maintaining structure and function of intestinal microbiome T2 - Comprehensive Gut Microbiota N2 - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota. KW - Vitamin A KW - Vitamin B KW - Thiamine KW - Riboflavin KW - Niacin Y1 - 2022 SN - 978-0-12-822036-8 U6 - https://doi.org/10.1016/B978-0-12-819265-8.00043-7 SP - 320 EP - 334 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Gkatzogias, Konstantinos A1 - Veljkoviv, Ana A1 - Pohoryles, Daniel A. A1 - Tsionis, Georgios A1 - Bournas, Dionysios A. A1 - Crowley, Helen A1 - Norlén, Hedvig A1 - Butenweg, Christoph A1 - Gervasio, Helena A1 - Manfredi, Vincenzo A1 - Masi, Angelo A1 - Zaharieva, Roumiana ED - Gkatzogias, Konstantinos ED - Tsionis, Georgios T1 - Policy practice and regional impact assessment for building renovation T2 - REEBUILD Integrated Techniques for the Seismic Strengthening & Energy Efficiency of Existing Buildings N2 - The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent. Y1 - 2022 SN - 978-92-76-60454-9 U6 - https://doi.org/10.2760/883122 SN - 1831-9424 SP - 1 EP - 68 PB - Publications Office of the European Union CY - Luxembourg ER - TY - CHAP A1 - Weber, Felix A1 - Bomholt, Frederik A1 - Butenweg, Christoph ED - Bergmeister, Konrad ED - Fingerloos, Frank ED - Wörner, Johann-Dietrich T1 - Erdbeben- und Schwingungsschutz von Bauwerken T2 - 2023 BetonKalender: Wasserundurchlässiger Beton, Brückenbau N2 - Dieser Beitrag beschreibt die herkömmlichen Maßnahmen wie die Kapazitätsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die Dämpfungserhöhung der Struktur mittels Inter-Story-Dämpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Ergänzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. Für die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Berücksichtigung der wesentlichen Nichtlinearitäten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, Dämpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, ökonomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt. Y1 - 2022 SN - 9783433611180 SN - 9783433033753 U6 - https://doi.org/10.1002/9783433611180.ch16 N1 - Beton-Kalender, 112. Jahrgang (2023): Wasserundurchlässiger Beton, Brückenbau ausleihbar unter der Sig. 11 XCF 3-2023,2 SP - 779 EP - 859 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Butenweg, Christoph A1 - Thierauf, G. ED - Papadrakakis, M. ED - Topping, B.H.V. T1 - Automatic design of reinforced concrete structures with parallel computing T2 - Innovative computational methods for structural mechanics N2 - A concept for the analysis and optimal design of reinforced concrete structures is described. It is based on a nonlinear optimization algorithm and a finite element program for linear and nonlinear analysis of structures. With the aim of minimal cost design a two stage optimization using efficient gradient algorithm is developed. The optimization problems on global (structural) and local (crosssectional) level are formulated. A parallelization concept for solving the two stage optimization problem in minimal time is presented. Examples are included to illustrate the practical use and the effectively of the parallelization in the area of engineering design. Y1 - 1999 SN - 1-874672-05-9 U6 - https://doi.org/10.4203/csets.1.14 SP - 305 EP - 318 PB - Saxe-Coburg Publication CY - Edinburgh ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Kalker, Ines A1 - Mistler, Michael T1 - Numerical simulation of historic masonry buildings T2 - Antike Erdbeben im alpinen und zirkumalpinen Raum : Befunde und Probleme in archäologischer, historischer und seismologischer Sicht ; Beiträge des Interdisziplinären Workshops Schloss Hohenkammer, 14./15. Mai 2004 = Earthquakes in antiquity in the alpine and circum-alpine region / Gerhard H. Waldherr ; Anselm Smolka (Hrsg.) (Geographica Historica ; 24) Y1 - 2007 SN - 978-3-515-09030-8 ; 3-515-09030-4 SP - 171 EP - 189 PB - Franz Steiner Verlag CY - Stuttgart ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph T1 - Erdbebensichere Auslegung von Bauwerken nach DIN 4149:2005 T2 - Betonkalender 2008: Konstruktiver Wasserbau, erdbebensicheres Bauen. Band 2 Y1 - 2008 SN - 978-3-433-01839-2 (Print) ; 978-3-433-01854-5 (E-Book) U6 - https://doi.org/10.1002/9783433600702.ch5 SP - 1 EP - 54 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Butenweg, Christoph A1 - Gellert, Christoph T1 - Berechnung und Bemessung von durch Erdbeben beanspruchten Mauerwerksbauten nach DIN 4149 (04.2005) T2 - Mauerwerksbau-Praxis / Schubert ; Schneider ; Schoch (Hrsg.) Y1 - 2007 SN - 3-9343-6938-3 ; 978-3-9343-6938-2 SP - 363 EP - 393 PB - Werner Verlag CY - Berlin ER - TY - CHAP A1 - Butenweg, Christoph A1 - Ebenau, C. T1 - Entwicklung eines objekt-orientierten FE-Programms T2 - Forum Bauinformatik - Junge Wissenschaftler forschen, Cottbus '96 Y1 - 1996 SN - 978-3-18-313504-2 N1 - Fortschritt-Berichte VDI : Reihe 4, Bauingenieurwesen, Band 135 SP - 60 EP - 65 PB - VDI-Verlag CY - Düsseldorf ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Sherelkhan, Dinara K. A1 - Razzaque, Mohammed S. T1 - Vitamin D and Phosphate Interactions in Health and Disease T2 - Phosphate Metabolism N2 - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease. KW - Vitamin D KW - PTH KW - Phosphate KW - FGF23 KW - Klotho Y1 - 2022 SN - 978-3-030-91621-3 U6 - https://doi.org/10.1007/978-3-030-91623-7_5 SP - 37 EP - 46 PB - Springer CY - Cham ER - TY - CHAP A1 - Alexopoulos, Spiros T1 - Biomass technology and bio-fuels: Heating/cooling and power T2 - Renewable energy systems : theory, innovations, and intelligent applications / eds.: Socrates Kaplanis and Eleni Kaplani Y1 - 2013 SN - 9781624177415 SP - 501 EP - 523 PB - Nova Science Publ. CY - Hauppauge, NY ER -