TY - JOUR A1 - Sun, Hui A1 - Altherr, Lena A1 - Pei, Ji A1 - Pelz, Peter F. A1 - Yuan, Shouqi T1 - Optimal booster station design and operation under uncertain load JF - Applied Mechanics and Materials N2 - Given industrial applications, the costs for the operation and maintenance of a pump system typically far exceed its purchase price. For finding an optimal pump configuration which minimizes not only investment, but life-cycle costs, methods like Technical Operations Research which is based on Mixed-Integer Programming can be applied. However, during the planning phase, the designer is often faced with uncertain input data, e.g. future load demands can only be estimated. In this work, we deal with this uncertainty by developing a chance-constrained two-stage (CCTS) stochastic program. The design and operation of a booster station working under uncertain load demand are optimized to minimize total cost including purchase price, operation cost incurred by energy consumption and penalty cost resulting from water shortage. We find optimized system layouts using a sample average approximation (SAA) algorithm, and analyze the results for different risk levels of water shortage. By adjusting the risk level, the costs and performance range of the system can be balanced, and thus the system’s resilience can be engineered KW - Stochastic Programming KW - Chance Constraint KW - Engineering Application KW - Pump System KW - Water Distribution Y1 - 2018 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.102 SN - 1662-7482 VL - 885 SP - 102 EP - 115 PB - Trans Tech Publications CY - Bäch ER - TY - JOUR A1 - Altherr, Lena A1 - Brötz, Nicolas A1 - Dietrich, Ingo A1 - Gally, Tristan A1 - Geßner, Felix A1 - Kloberdanz, Hermann A1 - Leise, Philipp A1 - Pelz, Peter Franz A1 - Schlemmer, Pia A1 - Schmitt, Andreas T1 - Resilience in mechanical engineering - a concept for controlling uncertainty during design, production and usage phase of load-carrying structures JF - Applied Mechanics and Materials N2 - Resilience as a concept has found its way into different disciplines to describe the ability of an individual or system to withstand and adapt to changes in its environment. In this paper, we provide an overview of the concept in different communities and extend it to the area of mechanical engineering. Furthermore, we present metrics to measure resilience in technical systems and illustrate them by applying them to load-carrying structures. By giving application examples from the Collaborative Research Centre (CRC) 805, we show how the concept of resilience can be used to control uncertainty during different stages of product life. Y1 - 2018 SN - 1662-7482 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.187 VL - 885 SP - 187 EP - 198 PB - Trans Tech Publications CY - Bäch ER - TY - JOUR A1 - Rausch, Lea A1 - Friesen, John A1 - Altherr, Lena A1 - Meck, Marvin A1 - Pelz, Peter F. T1 - A holistic concept to design optimal water supply infrastructures for informal settlements using remote sensing data JF - Remote Sensing N2 - Ensuring access to water and sanitation for all is Goal No. 6 of the 17 UN Sustainability Development Goals to transform our world. As one step towards this goal, we present an approach that leverages remote sensing data to plan optimal water supply networks for informal urban settlements. The concept focuses on slums within large urban areas, which are often characterized by a lack of an appropriate water supply. We apply methods of mathematical optimization aiming to find a network describing the optimal supply infrastructure. Hereby, we choose between different decentral and central approaches combining supply by motorized vehicles with supply by pipe systems. For the purposes of illustration, we apply the approach to two small slum clusters in Dhaka and Dar es Salaam. We show our optimization results, which represent the lowest cost water supply systems possible. Additionally, we compare the optimal solutions of the two clusters (also for varying input parameters, such as population densities and slum size development over time) and describe how the result of the optimization depends on the entered remote sensing data. KW - water supply design KW - mathematical optimization KW - slum classification KW - remote sensing Y1 - 2018 SN - 2072-4292 U6 - https://doi.org/10.3390/rs10020216 VL - 10 IS - 2 SP - 1 EP - 23 PB - MDPI CY - Basel ER - TY - JOUR A1 - Altherr, Lena A1 - Ederer, Thorsten A1 - Pfetsch, Marc E. A1 - Pelz, Peter F. T1 - Maschinelles Design eines optimalen Getriebes JF - ATZ - Automobiltechnische Zeitschrift N2 - Nahezu 100.000 denkbare Strukturen kann ein Getriebe bei gleicher Funktion aufweisen - je nach Ganganzahl und gefordertem Freiheitsgrad. Mit dem traditionellen Ansatz bei der Entwicklung, einzelne vielversprechende Systemkonfigurationen manuell zu identifizieren und zu vergleichen, können leicht innovative und vor allem kostenminimale Lösungen übersehen werden. Im Rahmen eines Forschungsprojekts hat die TU Darmstadt spezielle Optimierungsmethoden angewendet, um auch bei großen Lösungsräumen zielsicher ein für die individuellen Zielstellungen optimales Layout zu finden. Y1 - 2018 SN - 2192-8800 U6 - https://doi.org/10.1007/s35148-018-0131-3 VL - 120 IS - 10 SP - 72 EP - 77 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Altherr, Lena A1 - Joggerst, Laura A1 - Leise, Philipp A1 - Pfetsch, Marc E. A1 - Schmitt, Andreas A1 - Wendt, Janine T1 - On obligations in the development process of resilient systems with algorithmic design methods JF - Applied Mechanics and Materials N2 - Advanced computational methods are needed both for the design of large systems and to compute high accuracy solutions. Such methods are efficient in computation, but the validation of results is very complex, and highly skilled auditors are needed to verify them. We investigate legal questions concerning obligations in the development phase, especially for technical systems developed using advanced methods. In particular, we consider methods of resilient and robust optimization. With these techniques, high performance solutions can be found, despite a high variety of input parameters. However, given the novelty of these methods, it is uncertain whether legal obligations are being met. The aim of this paper is to discuss if and how the choice of a specific computational method affects the developer’s product liability. The review of legal obligations in this paper is based on German law and focuses on the requirements that must be met during the design and development process. KW - legal obligations KW - product liability KW - design of technical systems KW - optimization KW - resilience Y1 - 2018 SN - 1662-7482 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.240 VL - 885 IS - 885 SP - 240 EP - 252 PB - Trans Tech Publications CY - Bäch ER - TY - JOUR A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian T1 - Einsatz von Text Analytics zur Unterstützung literaturintensiver Forschungsprozesse: Konzeption, Realisierung und Lessons Learned JF - Anwendungen und Konzepte der Wirtschaftsinformatik N2 - Das anhaltende Wachstum wissenschaftlicher Veröffentlichungen wirft die Fragestellung auf, wie Literaturana-lysen im Rahmen von Forschungsprozessen digitalisiert und somit produktiver realisiert werden können. Insbesondere in informationstechnischen Fachgebieten ist die Forschungspraxis durch ein rasant wachsendes Publikationsaufkommen gekennzeichnet. Infolgedessen bietet sich der Einsatz von Methoden der Textanalyse (Text Analytics) an, die Textdaten automatisch vorbereiten und verarbeiten können. Erkenntnisse entstehen dabei aus Analysen von Wortarten und Subgruppen, Korrelations- sowie Zeitreihenanalysen. Dieser Beitrag stellt die Konzeption und Realisierung eines Prototypen vor, mit dem Anwender bibliographische Daten aus der etablierten Literaturdatenbank EBSCO Discovery Service mithilfe textanalytischer Methoden erschließen können. Der Prototyp basiert auf dem Analysesystem IBM Watson Explorer, das Hochschulen lizenzkostenfrei zur Verfügung steht. Potenzielle Adressaten des Prototypen sind Forschungseinrichtungen, Beratungsunternehmen sowie Entscheidungsträger in Politik und Unternehmenspraxis. KW - Text Analytics KW - Literaturanalyse KW - Forschungsprozess KW - EBSCO Discovery Service KW - IBM Watson Explorer Y1 - 2018 U6 - https://doi.org/10.26034/lu.akwi.2018.3221 SN - 2296-4592 VL - 2018 IS - 8 SP - 1 EP - 6 PB - AKWI CY - Luzern ER - TY - JOUR A1 - Figueroa-Miranda, Gabriela A1 - Feng, Lingyan A1 - Shiu, Simon Chi-Chin A1 - Dirkzwager, Roderick Marshall A1 - Cheung, Yee-Wai A1 - Tanner, Julian Alexander A1 - Schöning, Michael Josef A1 - Offenhäusser, Andreas A1 - Mayer, Dirk T1 - Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability JF - Sensor and Actuators B: Chemical N2 - Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2017.07.117 SN - 0925-4005 VL - 255 IS - P1 SP - 235 EP - 243 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Koichiro A1 - Seki, Kosuke A1 - Suto, Takeyuki A1 - Werner, Frederik A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers JF - Sensor and Actuators B: Chemical N2 - The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration. Y1 - 2018 U6 - https://doi.org/10.1016/j.snb.2018.07.016 SN - 0925-4005 VL - 273 SP - 1328 EP - 1333 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Eckert, Alexander A1 - Rudolph, Tobias A1 - Guo, Jiaqi A1 - Mang, Thomas A1 - Walther, Andreas T1 - Exceptionally Ductile and Tough Biomimetic Artificial Nacre with Gas Barrier Function JF - Advanced Materials N2 - Synthetic mimics of natural high-performance structural materials have shown great and partly unforeseen opportunities for the design of multifunctional materials. For nacre-mimetic nanocomposites, it has remained extraordinarily challenging to make ductile materials with high stretchability at high fractions of reinforcements, which is however of crucial importance for flexible barrier materials. Here, highly ductile and tough nacre-mimetic nanocomposites are presented, by implementing weak, but many hydrogen bonds in a ternary nacre-mimetic system consisting of two polymers (poly(vinyl amine) and poly(vinyl alcohol)) and natural nanoclay (montmorillonite) to provide efficient energy dissipation and slippage at high nanoclay content (50 wt%). Tailored interactions enable exceptional combinations of ductility (close to 50% strain) and toughness (up to 27.5 MJ m⁻³). Extensive stress whitening, a clear sign of high internal dynamics at high internal cohesion, can be observed during mechanical deformation, and the materials can be folded like paper into origami planes without fracture. Overall, the new levels of ductility and toughness are unprecedented in highly reinforced bioinspired nanocomposites and are of critical importance to future applications, e.g., as barrier materials needed for encapsulation and as a printing substrate for flexible organic electronics. Y1 - 2018 U6 - https://doi.org/10.1002/adma.201802477 VL - 30 IS - 32 SP - Article number 1802477 PB - Wiley-VCH ER - TY - JOUR A1 - Lapitan, Denis G. A1 - Rogatkin, Dmitrii A. A1 - Persheyev, Sydulla K. A1 - Kotliar, Konstantin T1 - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter JF - Biomedizinische Technik N2 - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise. Y1 - 2018 U6 - https://doi.org/10.1515/bmt-2017-0060 SN - 0013-5585 VL - 63 IS - 4 SP - 439 EP - 444 PB - De Gruyter CY - Berlin ER -