TY  - CHAP
A1  - Blum, Yannik
A1  - Albanna, Walid
A1  - Benninghaus, Anne
A1  - Kotliar, Konstantin
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Vasomotion in retinal vessels of patients presenting post hemorrhagic hydrocephalus following subarachnoid hemorrhage
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen
N2  - Clearance of blood components and fluid drainage play a crucial role in subarachnoid hemorrhage (SAH) and post hemorrhagic hydrocephalus (PHH). With the involvement of interstitial fluid (ISF) and cerebrospinal fluid (CSF), two pathways for the clearance of fluid and solutes in the brain are proposed. Starting at the level of capillaries, flow of ISF follows along the basement membranes in the walls of cerebral arteries out of the parenchyma to drain into the lymphatics and CSF [1]–[3]. Conversely, it is shown that CSF enters the parenchyma between glial and pial basement membranes of penetrating arteries [4]–[6]. Nevertheless, the involved structures and the contribution of either flow pathway to fluid balance between the subarachnoid space and interstitial space remains controversial. Low frequency oscillations in vascular tone are referred to as vasomotion and corresponding vasomotion waves are modeled as the driving force for flow of ISF out of the parenchyma [7]. Retinal vessel analysis (RVA) allows non-invasive measurement of retinal vessel vasomotion with respect to diameter changes [8]. Thus, the aim of the study is to investigate vasomotion in RVA signals of SAH and PHH patients.
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
SP  - 38
EP  - 39
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Bayer, Robin
A1  - Hescheler, Jürgen
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Treating arterial hypertension in a cell culture well
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW
N2  - Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the “Deutsche Bluthochdruck Liga” this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model.
In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology.
Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
SP  - 5
EP  - 6
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Azar, Fouad
A1  - Digel, Ilya
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Utilization of fluorescence spectroscopy and neural networks in clinical analysis
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen
N2  - Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis.
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
SP  - 40
EP  - 41
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  -