TY - BOOK A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül A1 - Zhubanova, Azhar A. A1 - Digel, Ilya ED - Artmann, Gerhard ED - Temiz Artmann, Aysegül ED - Zhubanova, Azhar A. ED - Digel, Ilya T1 - Biological, physical and technical basics of cell engineering Y1 - 2018 SN - 978-981-10-7903-0 PB - Springer CY - Singapore ER - TY - JOUR A1 - Babilon, Katharina A1 - Wilbring, Daniela A1 - Tappert, Tim A1 - Pfaff, Raphael A1 - Enning, Manfred T1 - Schienenfahrzeugtechnik hands on – FH Aachen IMechE Railway Challenge JF - Ingenieurspiegel Y1 - 2018 SN - 1868-5919 IS - 2 SP - 20 EP - 22 PB - Public Verlag CY - Bingen ER - TY - JOUR A1 - Balakirski, Galina A1 - Kotliar, Konstantin A1 - Pauly, Karolin J. A1 - Krings, Laura K. A1 - Rübben, Albert A1 - Baron, Jens M. A1 - Schmitt, Laurenz T1 - Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience JF - Dermatologic Surgery N2 - BACKGROUND Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. PATIENTS AND METHODS All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records. RESULTS The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7% (19/284) of the cases. In 95% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients. CONCLUSION According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients. The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects. Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13% to 29% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis. To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients. Y1 - 2018 U6 - http://dx.doi.org/10.1097/DSS.0000000000001615 IS - 44 (12) SP - 1525 EP - 1536 PB - Wolters Kluwer ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - Efficiency comparison of the Wilcoxon tests in paired and independent survey samples JF - Metrika N2 - The efficiency concepts of Bahadur and Pitman are used to compare the Wilcoxon tests in paired and independent survey samples. A comparison through the length of corresponding confidence intervals is also done. Simple conditions characterizing the dominance of a procedure are derived. Statistical tests for checking these conditions are suggested and discussed. KW - Wilcoxon tests KW - Pitman efficiency KW - Bahadur efficiency KW - Length of confidence intervals KW - Kernel density estimator Y1 - 2018 U6 - http://dx.doi.org/10.1007/s00184-018-0661-4 SN - 1435-926X VL - 2018 IS - 81 SP - 891 EP - 930 PB - Springer CY - Berlin ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel A1 - Thiele, Jan Philipp T1 - Statistical inference for L²-distances to uniformity JF - Computational Statistics N2 - The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study. KW - Integrated empirical distribution (survival) function KW - Goodness-of-fit tests for uniformity KW - Numerical inversion of Laplace transforms KW - Coverage probability KW - Equivalence test Y1 - 2018 U6 - http://dx.doi.org/10.1007/s00180-018-0820-0 SN - 1613-9658 VL - 2018 IS - 33 SP - 1863 EP - 1896 PB - Springer CY - Berlin ER - TY - CHAP A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian ED - Hofmann, Georg Rainer ED - Alm, Wolfgang T1 - Unterstützung von Wissenstransferprozessen durch Erschließung von Literaturdatenbanken - ein gestaltungsorientierter Ansatz auf Basis von Text Analytics T2 - Wissenstransfer in der Wirtschaftsinformatik Fachgespräch im Rahmen der MKWI 2018 N2 - Angesichts des anhaltenden Wachstums wissenschaftlicher Veröffentlichungen werden Instrumente benötigt, um Literaturanalysen durch Digitalisierung produktiver zu gestalten. Dieser Beitrag stellt einen Ansatz vor, der bibliographische Daten aus der Literaturdatenbank EBSCO Discovery Service mithilfe von Text-Analytics-Methoden erschließt. Die Lösung basiert auf dem Textanalysesystem IBM Watson Explorer und eignet sich für explorative Literaturanalysen, um beispielsweise den Status quo emergierender Technologiefelder in der Literatur zu reflektieren. Die generierten Ergebnisse sind in den Kontext der zunehmenden Werkzeugunterstützung des Literaturrechercheprozesses einzuordnen und können für intra- sowie interinstitutionelle Wissenstransferprozesse in Forschungs- und Beratungskontexten genutzt werden. KW - Wissenstransfer KW - Text Analytics KW - Literaturdaten KW - Literaturanalyse KW - Literatur-analyse-prozess Y1 - 2018 SN - 9783981844207 N1 - MKWI 2018: Multikonferenz Wirtschaftsinformatik 2018 in Lüneburg, 06.03.2018-09.03.2018 SP - 6 EP - 15 PB - IMI-Verlag ; Hochschule Aschaffenburg, Information Management Institut CY - Aschaffenburg ER - TY - JOUR A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian T1 - Einsatz von Text Analytics zur Unterstützung literaturintensiver Forschungsprozesse: Konzeption, Realisierung und Lessons Learned JF - Anwendungen und Konzepte der Wirtschaftsinformatik N2 - Das anhaltende Wachstum wissenschaftlicher Veröffentlichungen wirft die Fragestellung auf, wie Literaturana-lysen im Rahmen von Forschungsprozessen digitalisiert und somit produktiver realisiert werden können. Insbesondere in informationstechnischen Fachgebieten ist die Forschungspraxis durch ein rasant wachsendes Publikationsaufkommen gekennzeichnet. Infolgedessen bietet sich der Einsatz von Methoden der Textanalyse (Text Analytics) an, die Textdaten automatisch vorbereiten und verarbeiten können. Erkenntnisse entstehen dabei aus Analysen von Wortarten und Subgruppen, Korrelations- sowie Zeitreihenanalysen. Dieser Beitrag stellt die Konzeption und Realisierung eines Prototypen vor, mit dem Anwender bibliographische Daten aus der etablierten Literaturdatenbank EBSCO Discovery Service mithilfe textanalytischer Methoden erschließen können. Der Prototyp basiert auf dem Analysesystem IBM Watson Explorer, das Hochschulen lizenzkostenfrei zur Verfügung steht. Potenzielle Adressaten des Prototypen sind Forschungseinrichtungen, Beratungsunternehmen sowie Entscheidungsträger in Politik und Unternehmenspraxis. KW - Text Analytics KW - Literaturanalyse KW - Forschungsprozess KW - EBSCO Discovery Service KW - IBM Watson Explorer Y1 - 2018 U6 - http://dx.doi.org/10.26034/lu.akwi.2018.3221 SN - 2296-4592 VL - 2018 IS - 8 SP - 1 EP - 6 PB - AKWI CY - Luzern ER - TY - CHAP A1 - Bensberg, Frank A1 - Auth, Gunnar A1 - Czarnecki, Christian A1 - Wörndle, Christopher ED - Kemal İlter, H. T1 - Transforming literature-intensive research processes through text analytics – design, implementation and lessons learned N2 - The continuing growth of scientific publications raises the question how research processes can be digitalized and thus realized more productively. Especially in information technology fields, research practice is characterized by a rapidly growing volume of publications. For the search process various information systems exist. However, the analysis of the published content is still a highly manual task. Therefore, we propose a text analytics system that allows a fully digitalized analysis of literature sources. We have realized a prototype by using EBSCO Discovery Service in combination with IBM Watson Explorer and demonstrated the results in real-life research projects. Potential addressees are research institutions, consulting firms, and decision-makers in politics and business practice. KW - Text analytics KW - Text mining KW - Literature review KW - Research process Y1 - 2018 U6 - http://dx.doi.org/10.6084/m9.figshare.7582073.v1 N1 - 5th International Management Information Systems Conference. October 24-26 2018, Ankara ER - TY - JOUR A1 - Berg, Alexander-Karl A1 - Schleser, Markus A1 - Delidovich, Artem A1 - Houben, Alexander T1 - Ultraschallunterstützter Schmelzklebstoffauftrag JF - adhäsion KLEBEN & DICHTEN Y1 - 2018 U6 - http://dx.doi.org/10.1007/s35145-018-0089-z VL - Volume 62 IS - Issue 12 SP - 32 EP - 37 PB - Springer ER - TY - RPRT A1 - Bernecker, Andreas A1 - Boyer, Pierre A1 - Gathmann, Christina T1 - The Role of Electoral Incentives for Policy Innovation: Evidence from the US Welfare Reform T2 - CESifo Working Paper Y1 - 2018 SN - ISSN 2364‐1428 (electronic version) IS - No. 6964 ER -