TY  - JOUR
A1  - Biselli, Manfred
A1  - Thömmes, J.
A1  - Kula, M.-R.
A1  - Wandrey, Christian
T1  - Batch kinetic data of hybridoma growth and productivity as a basis for the simulation of antibody production in various culture systems /  Thömmes, J. ; Biselli, M. ; Kula, M.-R. ; Wandrey, C.
JF  - Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier
Y1  - 1994
SN  - 0750618450
N1  - Meeting / European Society for Animal Cell Technology ; 12
SP  - 513
EP  - 517
PB  - Butterworth-Heinemann
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Burger, René
A1  - Lindner, Simon
A1  - Rumpf, Jessica
A1  - Do, Xuan Tung
A1  - Diehl, Bernd W.K.
A1  - Rehahn, Matthias
A1  - Monakhova, Yulia
A1  - Schulze, Margit
T1  - Benchtop versus high field NMR: Comparable performance found for the molecular weight determination of lignin
JF  - Journal of Pharmaceutical and Biomedical Analysis
N2  - Lignin is a promising renewable biopolymer being investigated worldwide as an environmentally benign substitute of fossil-based aromatic compounds, e.g. for the use as an excipient with antioxidant and antimicrobial properties in drug delivery or even as active compound. For its successful implementation into process streams, a quick, easy, and reliable method is needed for its molecular weight determination. Here we present a method using 1H spectra of benchtop as well as conventional NMR systems in combination with multivariate data analysis, to determine lignin’s molecular weight (Mw and Mn) and polydispersity index (PDI). A set of 36 organosolv lignin samples (from Miscanthus x giganteus, Paulownia tomentosa and Silphium perfoliatum) was used for the calibration and cross validation, and 17 samples were used as external validation set. Validation errors between 5.6% and 12.9% were achieved for all parameters on all NMR devices (43, 60, 500 and 600 MHz). Surprisingly, no significant difference in the performance of the benchtop and high-field devices was found. This facilitates the application of this method for determining lignin’s molecular weight in an industrial environment because of the low maintenance expenditure, small footprint, ruggedness, and low cost of permanent magnet benchtop NMR systems.
KW  - NMR
KW  - PLS-regression
KW  - Molecular weight determination
KW  - Chemometrics
KW  - Biomass
Y1  - 2022
SN  - 0731-7085
U6  - http://dx.doi.org/10.1016/j.jpba.2022.114649
VL  - 212
IS  - Article number: 114649
PB  - Elsevier
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Iding, Hans
A1  - Dünnwald, Thomas
A1  - Greiner, Lasse
A1  - Liese, Andreas
A1  - Müller, Michael
A1  - Siegert, Petra
A1  - Grötzinger, Joachim
A1  - Demir, Ayhan S.
A1  - Pohl, Martina
T1  - Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones
JF  - Chemistry - a European journal
Y1  - 2000
SN  - 1521-3765 (E-Journal); 0947-6539 (Print)
VL  - Vol. 6
IS  - Iss. 8
SP  - 1483
EP  - 1495
ER  - 
TY  - CHAP
A1  - Muffler, Kai
A1  - Poth, Sabastian
A1  - Sieker, Tim
A1  - Tippkötter, Nils
A1  - Ulber, Roland
A1  - Sell, Dieter
ED  - Moo-Young, Murray
T1  - Bio-feedstocks
T2  - Comprehensive biotechnology : principles and practices in industry, agcriculture, medicine and the environment. Volume 2: Engineering fundamentals of biotechnology
Y1  - 2011
SN  - 978-0-444-53352-4
U6  - http://dx.doi.org/10.1016/B978-0-08-088504-9.00088-X
SP  - 93
EP  - 101
PB  - Elsevier
CY  - Amsterdam
ET  - 2. edition
ER  - 
TY  - JOUR
A1  - Selmer, Thorsten
A1  - Netz, Daili Jacqueline Aguilar
A1  - Pohl, Regula
A1  - Beck-Sickinger, Annette G.
T1  - Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus / Netz, Daili Jacqueline Aguilar ; Pohl, Regula ; Beck-Sickinger, Annette G. ; Selmer, Thorsten ; Pierik, Antonio J. ;  Carmo de Frei
JF  - Journal of Molecular Biology. 319 (2002), H. 3
Y1  - 2002
SN  - 0022-2836
SP  - 745
EP  - 756
ER  - 
TY  - CHAP
A1  - Kasper, Katharina
A1  - Schiffels, Johannes
A1  - Krafft, Simone
A1  - Kuperjans, Isabel
A1  - Elbers, Gereon
A1  - Selmer, Thorsten
T1  - Biogas Production on Demand Regulated by Butyric Acid Addition
T2  - IOP Conference Series: Earth and Environmental Science. Bd. 32
Y1  - 2016
U6  - http://dx.doi.org/10.1088/1755-1315/32/1/012009
SN  - 1755-1315
N1  - ICARET 2016, International Conference on Advances in Renewable Energy and Technologies, Putrajaya, MY, Feb 23-25, 2016
VL  - 32
SP  - 012009/1
EP  - 012009/4
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, C.
A1  - Bork, M.
A1  - Kayser, Peter
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells
JF  - Medical and biological engineering and computing. 41 (2003), H. 3
Y1  - 2003
SN  - 0140-0118
SP  - 350
EP  - 356
ER  - 
TY  - BOOK
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
A1  - Zhubanova, Azhar A.
A1  - Digel, Ilya
ED  - Artmann, Gerhard
ED  - Temiz Artmann, Aysegül
ED  - Zhubanova, Azhar A.
ED  - Digel, Ilya
T1  - Biological, physical and technical basics of cell engineering
Y1  - 2018
SN  - 978-981-10-7903-0
PB  - Springer
CY  - Singapore
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Hilbert, U.
A1  - Jelinek, N.
A1  - Schmidt, S.
T1  - Bioprocess development for the cultivation of human T-lymphocytes / Hilbert, U. ; Jelinek, N.  Schmidt, S. ; Biselli, M.
JF  - Engineering in Life Sciences. 1 (2001)
Y1  - 2001
SN  - 1618-0240
SP  - 20
EP  - 23
ER  - 
TY  - BOOK
A1  - Wagemann, Kurt
A1  - Tippkötter, Nils
T1  - Biorefineries / Kurt Wagemann, Nils Tippkötter (editors)
T3  - Advances in biochemical engineering/biotechnology book series (ABE)
Y1  - 2019
SN  - 978-3-319-97117-9
SN  - 978-3-319-97119-3
U6  - http://dx.doi.org/10.1007/978-3-319-97119-3
PB  - Springer
CY  - Cham (Switzerland)
ER  -