TY  - CHAP
A1  - Beer, Stefan
A1  - Haidn, O.J.
A1  - Willms, Herbert
ED  - Carvalho, Maria da Graça
T1  - Control of stoichiometric propellant supply in an H2/O2-spinning reserve system
T2  - Combustion technologies for a clean environment : selected papers from the proceedings of the first international conference, Vilamoura, Portugal, September 3 - 6, 1991. - (Energy, combustion and the environment ;1)
Y1  - 1995
SN  - 2-88124-619-2
SP  - 825
EP  - 838
PB  - Gordon and Breach
CY  - Basel [u.a.]
ER  - 
TY  - GEN
A1  - Tippkötter, Nils
A1  - Wulfhorst, H.
A1  - Mogue, N.
A1  - Möhring, S.
A1  - Roth, J.
A1  - Ulber, Roland
T1  - Spektrometrische Messung und Modellierung der enzymatischen Hydrolyse von Biomasse nach Organosolv- und Liquid Hot Water-Aufschlüssen (LHW)
T2  - Chemie Ingenieur Technik
N2  - In diesem Beitrag wird die NIR- und MIR-Spektrometrie in Kombination mit multivariaten Kalibrationsmodellen zur Analyse von Monosacchariden und Cellulose aus Biomasse etabliert. Spektrengemischter Standardlösungen mit definierten Glucose- und Xylosekonzentrationen in Wasser werden im NIR-(Lambda 750, Perkin Elmer, USA) und MIR-Bereich (Spektrum 100, PerkinElmer) in Gegenwart von entweder Carboxymethylcellulose oder Grasfasern aufgenommen. Darauf basierend werden Kalibrationsmodelle (Unscrambler®, CAMO-Software AS, Norwegen) entwickelt und zur Vorhersage der Zuckerkonzentration in den Hydrolyseproben und der Celluloseanteile angewendet. Darüber hinaus wird die Partikelgröße der Rohstoffe bestimmt. Die Messergebnisse bilden die experimentelle Basis für die numerische Modellierung der Reaktionskinetik der enzymatischen Hydrolyse von Lignocellulose. Das Modell kombiniert die Bilanzierung der Partikelgrößenverteilungen mit der Multienzymkinetik. Dabei werden neben der Partikelgrößenverteilung und der Substratkonzentration die Zusammensetzung der Rohstoffe nach Vorbehandlung sowie die Produktinhibierung und mehrere enzymatische Aktivitäten berücksichtigt. Das Modell ermöglicht es, die Partikelgrößenverteilungen und die Konzentrationen der Substrate und Produkte während der Hydrolyse vorherzusagen und die kinetischen Parameter im Batch- sowie im Fed-Batch-Reaktor zu bestimmen.
Y1  - 2014
U6  - https://doi.org/10.1002/cite.201450269
SN  - 0009-286X
SN  - 1522-2640 (eISSN)
N1  - ProcessNet-Jahrestagung 2014 und 31. DECHEMA-Jahrestagung der Biotechnologen, 30. September - 2. Oktober 2014, Eurogress Aachen
VL  - 86
IS  - 9
SP  - 1584
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Wollny, S.
A1  - Stadtmüller, R.
A1  - Tippkötter, Nils
A1  - Oster, J.
A1  - Kampeis, P.
A1  - Ulber, Roland
T1  - Optimierung der selektiven Aufarbeitung von Proteinen mit Aptamer-funktionalisierten Magnetpartikeln
T2  - Chemie Ingenieur Technik
N2  - Die Herstellung pharmakologisch relevanter Proteine durch Mikroorganismen führt eine mehrstufige Aufarbeitung mit sich. Durch die Verwendung von Aptameren, kurzen einzelsträngigen DNA- oder RNA-Oligonukleotiden immobilisiert auf funktionalisierten, wiederverwendbaren Magnetpartikeln, können mehrere dieser Abtrennungsoperationen kombiniert und damit die Prozesskosten minimiert werden. Aufgrund der definierten dreidimensionalen Struktur können Aptamere kleine organische Moleküle hochspezifisch binden. Im vorgestellten Projekt wird die Aufarbeitung von His6-GFP als Modellprotein mithilfe der mit Aptamer funktionalisierten Magnetpartikel durchgeführt. In bisherigen Versuchen wurde die Bindung von Aptameren auf den magnetischen Partikeln sowie die Bindung des Modellproteins GFP auf den Partikeln optimiert. Des Weiteren wurden mehrere Strategien zur Elution des GFPs von den Partikeln verfolgt, um den Proteinertrag zu maximieren und die Partikel rezyklieren zu können. Die Untersuchung unspezifischer Bindungen von Zelltrümmern und Proteinen an die Magnetpartikel wurde mithilfe eines konfokalen Laser-Scanning-Mikroskops durchgeführt.
Y1  - 2012
U6  - https://doi.org/10.1002/cite.201250031
SN  - 0009-286X
SN  - 1522-2640 (eISSN)
N1  - ProcessNet-Jahrestagung 2012 und 30. DECHEMA-Jahrestagung der Biotechnologen, 10. – 13. September 2012, Karlsruhe
VL  - 84
IS  - 8
SP  - 1203
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Tastambek, Kuanysh T.
A1  - Sherelkhan, Dinara K.
A1  - Jussupova, Dariya B.
A1  - Altynbay, Nazym P.
T1  - Low-rank coal as a source of humic substances for soil amendment and fertility management
JF  - Agriculture
N2  - Humic substances (HS), as important environmental components, are essential to soil health and agricultural sustainability. The usage of low-rank coal (LRC) for energy generation has declined considerably due to the growing popularity of renewable energy sources and gas. However, their potential as soil amendment aimed to maintain soil quality and productivity deserves more recognition. LRC, a highly heterogeneous material in nature, contains large quantities of HS and may effectively help to restore the physicochemical, biological, and ecological functionality of soil. Multiple emerging studies support the view that LRC and its derivatives can positively impact the soil microclimate, nutrient status, and organic matter turnover. Moreover, the phytotoxic effects of some pollutants can be reduced by subsequent LRC application. Broad geographical availability, relatively low cost, and good technical applicability of LRC offer the advantage of easy fulfilling soil amendment and conditioner requirements worldwide. This review analyzes and emphasizes the potential of LRC and its numerous forms/combinations for soil amelioration and crop production. A great benefit would be a systematic investment strategy implicating safe utilization and long-term application of LRC for sustainable agricultural production.
KW  - soil remediation
KW  - crop yield
KW  - soil health
KW  - soil amendment
KW  - low-rank coal
Y1  - 2021
U6  - https://doi.org/10.3390/agriculture11121261
SN  - 2077-0472
N1  - This article belongs to the Special Issue "From Waste to Fertilizer in Sustainable Agriculture"
VL  - 11
IS  - 12
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Tastambek, Kuanysh T.
A1  - Marat, Adel K.
A1  - Turaliyeva, Moldir A.
A1  - Kaiyrmanova, Gulzhan K.
T1  - Biotechnology of Microorganisms from Coal Environments: From Environmental Remediation to Energy Production
JF  - Biology
N2  - It was generally believed that coal sources are not favorable as live-in habitats for microorganisms due to their recalcitrant chemical nature and negligible decomposition. However, accumulating evidence has revealed the presence of diverse microbial groups in coal environments and their significant metabolic role in coal biogeochemical dynamics and ecosystem functioning. The high oxygen content, organic fractions, and lignin-like structures of lower-rank coals may provide effective means for microbial attack, still representing a greatly unexplored frontier in microbiology. Coal degradation/conversion technology by native bacterial and fungal species has great potential in agricultural development, chemical industry production, and environmental rehabilitation. Furthermore, native microalgal species can offer a sustainable energy source and an excellent bioremediation strategy applicable to coal spill/seam waters. Additionally, the measures of the fate of the microbial community would serve as an indicator of restoration progress on post-coal-mining sites. This review puts forward a comprehensive vision of coal biodegradation and bioprocessing by microorganisms native to coal environments for determining their biotechnological potential and possible applications.
Y1  - 2022
U6  - https://doi.org/10.3390/biology11091306
SN  - 2079-7737
N1  - This article belongs to the Special Issue "Microbial Ecology and Evolution in Extreme Environments"
VL  - 11
IS  - 9
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Niedermeier, Jana
A1  - Penner, Crystal
A1  - Usherovich, Samuel
A1  - Bélanger-Champagne, Camille
A1  - Paulßen, Elisabeth
A1  - Hoehr, Cornelia
T1  - Optical Fibers as Dosimeter Detectors for Mixed Proton/Neutron Fields - A Biological Dosimeter
JF  - electronics
N2  - In recent years, proton therapy has gained importance as a cancer treatment modality due to its conformality with the tumor and the sparing of healthy tissue. However, in the interaction of the protons with the beam line elements and patient tissues, potentially harmful secondary neutrons are always generated. To ensure that this neutron dose is as low as possible, treatment plans could be created to also account for and minimize the neutron dose. To monitor such a treatment plan, a compact, easy to use, and inexpensive dosimeter must be developed that not only measures the physical dose, but which can also distinguish between proton and neutron contributions. To that end, plastic optical fibers with scintillation materials (Gd₂O₂S:Tb, Gd₂O₂S:Eu, and YVO₄:Eu) were irradiated with protons and neutrons. It was confirmed that sensors with different scintillation materials have different sensitivities to protons and neutrons. A combination of these three scintillators can be used to build a detector array to create a biological dosimeter.
KW  - biological dosimeter
KW  - Bragg peak
KW  - relative dosimetry
KW  - optical fibers
KW  - proton therapy
KW  - protons
KW  - neutrons
Y1  - 2023
U6  - https://doi.org/10.3390/electronics12020324
SN  - 2079-9292
N1  - This article belongs to the Special Issue "Applications of Optical Fiber Sensors"
VL  - 12
IS  - 2
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Biewendt, Marcel
A1  - Böhnert, Arno
A1  - Blaschke, Florian
T1  - The repercussions of the digital twin in the automotive industry on the new marketing logic
JF  - European Journal of Marketing and Economics
N2  - Rapid development of virtual and data acquisition technology makes Digital Twin Technology (DT) one of the fundamental areas of research, while DT is one of the most promissory developments for the achievement of Industry 4.0. 48% percent of organisations implementing the Internet of Things are already using DT or plan to use DT in 2020. The global market for DT is expected to grow by 38 percent annually, reaching USD16 billion by 2023. In addition, the number of participating organisations using digital twins is expected to triple by 2022. DTs are characterised by the integration between physical and virtual spaces. The driving idea for DT is to develop, test and build our devices in a virtual environment. The objective of this paper is to study the impact of DT in the automotive industry on the new marketing logic. This paper outlines the current challenges and possible directions for the future DT in marketing. This paper will be helpful for managers in the industry to use the advantages and potentials of DT.
KW  - industry 4.0
KW  - marketing
KW  - automotive
KW  - digital twin
Y1  - 2020
U6  - https://doi.org/10.26417/229eim64f
SN  - 2601-8659
VL  - 4
IS  - 1
SP  - 68
EP  - 73
PB  - Revistia
CY  - London
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - On Hotelling’s T² test in a special paired sample case
JF  - Communications in Statistics - Theory and Methods
N2  - In a special paired sample case, Hotelling’s T² test based on the differences of the paired random vectors is the likelihood ratio test for testing the hypothesis that the paired random vectors have the same mean; with respect to a special group of affine linear transformations it is the uniformly most powerful invariant test for the general alternative of a difference in mean. We present an elementary straightforward proof of this result. The likelihood ratio test for testing the hypothesis that the covariance structure is of the assumed special form is derived and discussed. Applications to real data are given.
KW  - complete block symmetry
KW  - Hotelling’s T² test
KW  - likelihood ratio test
KW  - uniformly most powerful invariant test
Y1  - 2017
U6  - https://doi.org/10.1080/03610926.2017.1408828
SN  - 1532-415X
VL  - 48
IS  - 2
SP  - 257
EP  - 267
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - CHAP
A1  - Hartmann, Axel
A1  - Kallweit, Stephan
A1  - Feldusen, Antje
A1  - Schröder, Wolfgang
T1  - Detection of upstream propagating sound waves at buffet flow using high-speed PIV
BT  - 16th International Symposium on Applications of Laser Techniques to Fluid Mechanics ; 9th to 12th July 2012 Lisbon, Portugal
Y1  - 2012
N1  - Aerodynamisches Institut <Aachen> ; International Symposium on Applications of Laser Techniques to Fluid Mechanics <16, 2012, Lissabon>
ER  - 
TY  - CHAP
A1  - Raatschen, Hans-Jürgen
T1  - Von der Königlichen Höheren Maschinenbauschule Aachen zu den Ingenieurfachbereichen der FH Aachen
T2  - Ingenieurfreunde FH Aachen : 75 Jahre Förderverein; Elektrotechnik und Informationstechnik, Luft- und Raumfahrttechnik, Maschinenbau und Mechatronik
KW  - Geschichte
Y1  - 2010
SN  - 978-3-941704-03-9
SP  - 13
EP  - 18
PB  - Klinkenberg
CY  - Aachen
ER  -