TY  - CHAP
A1  - Wolf, C. Roland
A1  - Kapelyukh, Yury
A1  - Scheer, Nico
A1  - Henderson, Colin J.
ED  - Wilson, Alan G. E.
T1  - Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs
N2  - The use of transgenic animal models has transformed our knowledge of complex biochemical pathways in vivo. It has allowed disease processes to be modelled and used in the development of new disease prevention and treatment strategies. They can also be used to define cell- and tissue-specific pathways of gene regulation. A further major application is in the area of preclinical development where such models can be used to define pathways of chemical toxicity, and the pathways that regulate drug disposition. One major application of this approach is the humanisation of mice for the proteins that control drug metabolism and disposition. Such models can have numerous applications in the development of drugs and in their more sophisticated use in the clinic.
Y1  - 2015
SN  - 978-1-78262-778-4
U6  - http://dx.doi.org/10.1039/9781782622376-00152
SP  - 152
EP  - 176
PB  - RSC Publ.
CY  - Cambridge
ER  - 
TY  - CHAP
A1  - Fiedler, Gerda
A1  - Henn, Gudrun
A1  - Melcher, Karin
ED  - Morschheuser, Petra
T1  - ANPAK - Ein Anpassungskurs für Studienanfänger in den Ingenieurwissenschaften
T2  - Qualifizierung von Studierenden im Student-Life-Cycle. Tagungsband zum Mosbacher Tag der Lehre am 23.10.2014 /
Y1  - 2015
SN  - 978-3-943656-02-2
SP  - 90
EP  - 93
PB  - Duale Hochschule Baden-Württemberg (DHBW)
CY  - Mosbach
ER  - 
TY  - THES
A1  - Bassam Abduljabbar, Rasha
T1  - Physikalisch-chemische Steuerung der Proteinstabilität in biologischen Systemen
T1  - Physico-chemical management of protein stability in biological systems
Y1  - 2015
ER  - 
TY  - THES
A1  - Goßmann, Matthias
T1  - Entwicklung eines autokontraktilen Herzmuskelmodells zur funktionalen Medikamenten- und Toxinforschung
Y1  - 2015
N1  - Duisburg, Essen, Universität Duisburg-Essen, Diss., 2015
PB  - Universitätsbibliothek Duisburg-Essen
CY  - Duisburg ; Essen
ER  - 
TY  - THES
A1  - Seifarth, Volker
T1  - Ureteral tissue engineering : development of a bioreactor system and subsequent characterization of the generated biohybrids
Y1  - 2015
N1  - Duisburg, Essen, Universität Duisburg-Essen, Diss., 2015
PB  - Universitätsbibliothek Duisburg-Essen
CY  - Duisburg ; Essen
ER  - 
TY  - CHAP
A1  - Weber, Tobias
A1  - Englhard, Markus
A1  - Hailer, Benjamin
A1  - Arent, Jan-Christoph
T1  - Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling
T2  - Proceedings of SAMPE Europe Conference, Amiens , France
Y1  - 2015
SP  - 1
EP  - 10
ER  - 
TY  - CHAP
A1  - Weber, Tobias
T1  - Manufacturing Process Simulation for Tooling Optimization: Reduction of Quality Issues During Autoclave Manufacturing of Composite Parts
T2  - Proceedings of SAMPE Europe Conference 2015, Amiens, France
Y1  - 2015
SP  - 1
EP  - 8
ER  - 
TY  - CHAP
A1  - Otten, D.
A1  - Schmid, M.
A1  - Weber, Tobias
T1  - Advances In Sheet Metal-Forming: Reduction Of Tooling Cost By Methodical Optimization
T2  - Proceedings of SAMPE Europe Conference, Amiens , France
Y1  - 2015
ER  - 
TY  - JOUR
A1  - Hager, Jonathan
A1  - Hentschke, Reinhard
A1  - Hojdis, Nils
A1  - Karimi-Varzaneh, Hossein Ali
T1  - Computer Simulation of Particle–Particle Interaction in a Model Polymer Nanocomposite
JF  - Macromolecules
Y1  - 2015
U6  - http://dx.doi.org/10.1021/acs.macromol.5b01864
SN  - 1520-5835
VL  - 48
IS  - 24
SP  - 9039
EP  - 9049
ER  - 
TY  - JOUR
A1  - Klettke, Tanja
A1  - Homburg, Carsten
A1  - Gell, Sebastian
T1  - How to measure analyst forecast effort
JF  - European Accounting Review
N2  - We introduce a new way to measure the forecast effort that analysts devote to their earnings forecasts by measuring the analyst's general effort for all covered firms. While the commonly applied effort measure is based on analyst behaviour for one firm, our measure considers analyst behaviour for all covered firms. Our general effort measure captures additional information about analyst effort and thus can identify accurate forecasts. We emphasise the importance of investigating analyst behaviour in a larger context and argue that analysts who generally devote substantial forecast effort are also likely to devote substantial effort to a specific firm, even if this effort might not be captured by a firm-specific measure. Empirical results reveal that analysts who devote higher general forecast effort issue more accurate forecasts. Additional investigations show that analysts' career prospects improve with higher general forecast effort. Our measure improves on existing methods as it has higher explanatory power regarding differences in forecast accuracy than the commonly applied effort measure. Additionally, it can address research questions that cannot be examined with a firm-specific measure. It provides a simple but comprehensive way to identify accurate analysts.
Y1  - 2015
U6  - http://dx.doi.org/10.1080/09638180.2014.909291
SN  - 0963-8180
VL  - 24
IS  - 1
SP  - 129
EP  - 146
PB  - Taylor & Francis
CY  - London
ER  -