TY  - CHAP
A1  - Al-Kaidy, H.
A1  - Ulber, R.
A1  - Tippkötter, Nils
T1  - A platform technology for the automated reaction control in magnetizable micro-fluidic droplets
T2  - Biomaterials - made in bioreactors : book of abstracts, May 26 - 28, 2014, Radisson Blu Park Hotel and Conference Dentre, Radebeul, Germany
Y1  - 2014
SP  - 21
EP  - 22
PB  - DECHEMA
CY  - Frankfurt am Main
ER  - 
TY  - JOUR
A1  - Thiel, Alexander
A1  - Muffler, Kai
A1  - Tippkötter, Nils
A1  - Suck, Kirstin
A1  - Sohling, Ulrich
A1  - Hruschka, Steffen M.
A1  - Ulber, Roland
T1  - A novel integrated downstream processing approach to recover sinapic acid, phytic acid and proteins from rapeseed meal
JF  - Journal of Chemical Technology and Biotechnology
N2  - BACKGROUND
Currently, several techniques exist for the downstream processing of protein, phytic acid and sinapic acid from rapeseed and rapeseed meal, but no technique has been developed to separate all of the components in one process. In this work, two new downstream processing strategies focusing on recovering sinapic acid, phytic acid and protein from rapeseed meal were established.

RESULTS
The sinapic acid content was enhanced by a factor of 4.5 with one method and 5.1 with the other. The isolation of sinapic acid was accomplished using a zeolite-based adsorbent with high adsorptive and optimal desorption characteristics. Phytic acid was isolated using the anion-exchange resin Purolite A200®. In addition, the processes resulted in two separated protein fractions. The ratios of globulin and albumin ratio to the total protein were 59.2% and 40.1%, respectively. The steps were then combined in two different ways: (a) a ‘sequential process’ using the zeolite and A200 in batch processes; and (b) a ‘parallel process’ using only A200 in a chromatographic system to separate all of the compounds.

CONCLUSIONS
It can be concluded that isolation of all three components was possible in both processes. These could enhance the added value of current processes using rapeseed meal as a protein source. © 2015 Society of Chemical Industry
Y1  - 2015
U6  - http://dx.doi.org/10.1002/jctb.4664
VL  - 90
IS  - 11
SP  - 1999
EP  - 2006
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - PAT
A1  - Stadtmüller, Ralf
A1  - Tippkötter, Nils
A1  - Ulber, Roland
T1  - A method for production of single-stranded nucleic acids [Europäische Patentanmeldung]
Y1  - 2013
PB  - Europäisches Patentamt
CY  - Den Hague
ER  -