TY  - CHAP
A1  - Simsek, Beril
A1  - Krause, Hans-Joachim
A1  - Engelmann, Ulrich M.
ED  - Digel, Ilya
ED  - Staat, Manfred
ED  - Trzewik, Jürgen
ED  - Sielemann, Stefanie
ED  - Erni, Daniel
ED  - Zylka, Waldemar
T1  - Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection
T2  - 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
N2  - Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs’ flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
SP  - 27
EP  - 28
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Ruge, C.
A1  - Müller-Veggian, Mattea
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - A long-term stable macroporoustype EIS structure for electrochemical sensor applications
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 21
EP  - 25
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems
JF  - Sensors and Actuators B. 103 (2004), H. 1-2
Y1  - 2004
SN  - 0925-4005
SP  - 429
EP  - 435
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip“ pH sensor
JF  - Sensors. 3 (2003), H. 9
Y1  - 2003
SN  - 1424-8220
SP  - 330
EP  - 339
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Krings, T.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - A „hybrid“ thin-film pH sensor with integrated thick-film reference
JF  - Sensors. 1 (2001), H. 6
Y1  - 2001
SN  - 1424-8220
SP  - 183
EP  - 192
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Dawgul, M.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology
JF  - Electrochimica Acta. 51 (2005), H. 5
Y1  - 2005
SN  - 0013-4686
U6  - http://dx.doi.org/10.1016/j.electacta.2005.04.063
SP  - 930
EP  - 937
ER  - 
TY  - CHAP
A1  - Sildatke, Michael
A1  - Karwanni, Hendrik
A1  - Kraft, Bodo
A1  - Schmidts, Oliver
A1  - Zündorf, Albert
T1  - Automated Software Quality Monitoring in Research Collaboration Projects
T2  - ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops
Y1  - 2020
U6  - http://dx.doi.org/10.1145/3387940.3391478
SP  - 603
EP  - 610
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
A1  - Schuh, G.
A1  - Levering, V.
T1  - PROPLAN / Schuh, G.; Siepmann, Th.; Levering, V.
JF  - Handbook on architectures of information systems : with 24 tables / Peter Bernus ... (ed.)
Y1  - 1998
SN  - 3-540-64453-9
N1  - International handbooks on information systems ; 1
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
A1  - Rupietta, D.
T1  - Closer to the customer with computerized  product support
JF  - Technische Mitteilungen Krupp (1993)
Y1  - 1993
CY  - Essen
ER  - 
TY  - BOOK
A1  - Siepmann, Thomas
T1  - Modeller for Value Systems
Y1  - 1997
PB  - Erasmus Universiteit Rotterdam
CY  - Rotterdam
ER  -