TY  - JOUR
A1  - Huck, Christina
A1  - Schiffels, Johannes
A1  - Herrera, Cony N.
A1  - Schelden, Maximilian
A1  - Selmer, Thorsten
A1  - Poghossian, Arshak
A1  - Baumann, Marcus
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor
JF  - Physica Status Solidi (A)
N2  - Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the “welfare” of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis–Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.
Y1  - 2013
U6  - http://dx.doi.org/10.1002/pssa.201200900
SN  - 0031-8965
VL  - 210
IS  - 5
SP  - 926
EP  - 931
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Schultze, Joachim W.
T1  - Measuring seven parameters by two ISFET modules in a microcell set-up
JF  - Int. Journal of Computational Engineering Science. 4 (2003), H. 2
Y1  - 2003
SN  - 1465-8763
SP  - 257
EP  - 260
ER  - 
TY  - CHAP
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Han, Y.
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Poghossian, Arshak
T1  - Markierungsfreie DNA-Detektion mit Silizium-Feldeffektsensoren – Messeffekte oder Artefakte?
T2  - Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau
Y1  - 2006
SN  - 3-8007-2939-3
SP  - 443
EP  - 446
PB  - VDE Verl.
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Han, Yinhua
A1  - Offenhäusser, Andreas
A1  - Ingebrandt, Sven
T1  - Markierungsfreie DNA-Detektion mit Silizium-Feldeffekt-Sensoren – Messeffekte oder Artefakte?
JF  - tm - Technisches Messen . 74 (2007), H. 9
Y1  - 2007
SN  - 0171-8096
SP  - 466
EP  - 476
ER  - 
TY  - JOUR
A1  - Gasparyan, Ferdinand V.
A1  - Poghossian, Arshak
A1  - Vitusevich, Svetlana A.
A1  - Petrychuk, Mykhaylo V.
A1  - Sydoruk, Viktor A.
A1  - Siqueira, José R. Jr.
A1  - Oliveira, Osvaldo N. Jr.
A1  - Offenhäusser, Andreas
A1  - Schöning, Michael Josef
T1  - Low-Frequency Noise in Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers
JF  - IEEE Sensors Journal. 11 (2011), H. 1
Y1  - 2011
SN  - 1530-437X
SP  - 142
EP  - 149
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Gasparyan, F. V.
A1  - Poghossian, Arshak
A1  - Vitusevich, S. A.
A1  - Petrychuk, M. V.
A1  - Sydoruk, V. A.
A1  - Surmalyan, A. V.
A1  - Siqueira, J. R.
A1  - Oliveira, O. N.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Low Frequency Noise In Electrolyte-Gate Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers
JF  - Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso
Y1  - 2009
SN  - 9780735406650
N1  - AIP conference proceedings ; 1129 ; International Conference on Noise and Fluctuations ; (20, 2009, Pisa)
SP  - 133
EP  - 136
PB  - American Inst. of Physics
CY  - Melville, NY
ER  - 
TY  - CHAP
A1  - Bohrn, Ulrich
A1  - Stütz, Evamaria
A1  - Fleischer, Maximilian
A1  - Schöning, Michael Josef
A1  - Wagner, Patrick
T1  - Living cell-based gas sensor system for the detection of acetone in air
Y1  - 2012
SN  - 978-3-9813484-2-2
U6  - http://dx.doi.org/10.5162/IMCS2012/3.2.3
SP  - 269
EP  - 272
ER  - 
TY  - JOUR
A1  - Ermelenko, Y.
A1  - Yoshinobu, T.
A1  - Mourzina, Y.
A1  - Furuichi, K.
A1  - Levichev, S.
A1  - Vlasov, Y.
A1  - Schöning, Michael Josef
A1  - Iwasaki, H.
T1  - Lithium sensor based on the laser scanning semiconductor transducer
JF  - Analytica Chimica Acta. 459 (2002), H. 1
Y1  - 2002
SN  - 0378-4304
SP  - 1
EP  - 9
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Weißbecker, G.
A1  - Schroth, P.
A1  - Schöning, Michael Josef
T1  - Linkage of inanimate structures to biological systems – smart materials in biological micro- nanosystems
JF  - Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.
Y1  - 2001
SN  - 3-540-67957-X
SP  - 149
EP  - 157
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - CHAP
A1  - Breuer, Lars
A1  - Raue, Markus
A1  - Mang, Thomas
A1  - Schöning, Michael Josef
A1  - Thoelen, Ronald
A1  - Wagner, Torsten
T1  - Light-stimulated hydrogel actuators with incorporated graphene oxide for microfluidic applications
T2  - 12. Dresdner Sensor-Symposium 2015
Y1  - 2015
U6  - http://dx.doi.org/10.5162/12dss2015/P5.8
SP  - 206
EP  - 209
ER  -