TY  - JOUR
A1  - Achtsnicht, Stefan
A1  - Tödter, Julia
A1  - Niehues, Julia
A1  - Telöken, Matthias
A1  - Offenhäusser, Andreas
A1  - Krause, Hans-Joachim
A1  - Schröper, Florian
T1  - 3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection
JF  - Sensors
N2  - For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.
Y1  - 2019
U6  - https://doi.org/10.3390/s19010148
SN  - 1424-8220
VL  - 19
IS  - 1
PB  - MDPI
CY  - Basel
ER  - 
TY  - BOOK
A1  - Krause, Thomas
A1  - Ulke, Bernd
A1  - Martin, Joachim
A1  - Lemke, Jörg
A1  - Sparla, Peter
A1  - Streit, Wilfried
ED  - Krause, Thomas
ED  - Ulke, Bernd
T1  - Übungsaufgaben und Berechnungen für den Baubetrieb: Klausurvorbereitung mit ausführlichen Lösungen
Y1  - 2019
SN  - 978-3-658-23126-2 (Print) 978-3-658-23127-9 (Online)
N1  - Vorangegangen ist Krause, Thomas Beispiele aus der Baubetriebspraxis
gedruckt in der Bereichsbibliothek Bayernallee unter der Signatur 11 XBS 90(3)
PB  - Springer Vieweg
CY  - Wiesbaden
ET  - 3. Auflage
ER  - 
TY  - CHAP
A1  - Kurz, Melanie
T1  - Betrifft Design : von historischen Zukunftsperspektiven zu gegenwärtigen Vergangenheitssehnsüchten
T2  - Positionen des Neuen : Zukunft im Design
Y1  - 2019
SN  - 978-3-89986-301-7
SP  - 136
EP  - 144
PB  - avedition
CY  - Stuttgart
ER  -