TY - JOUR A1 - Linden, A. A1 - Fischöder, M. A1 - Laack, Walter van A1 - Staat, Manfred T1 - Einschränkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur JF - OUP Zeitschrift für die orthopädische und unfallchirurgische Praxis N2 - Die fibulare Bandruptur zählt zu einer der am häufigsten auftretenden Verletzungen des Bewegungsapparats. In den meisten Fällen wird heute die konservativ frühfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschränkung von Taluskippung und Talusvorschub untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" Röntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint. N2 - The ankle sprain is actually one of the most common injuries. Nowadays the conservative pre-functional therapy with ankle braces is generally preferred. In the present study 14 different ankle braces were tested with regard to their ability to constrict the talar tilt and anterior drawer displacement. As part of the tests a wooden model of a foot was used in order to simulate an ankle sprain. This model was clamped in a Scheuba-device with different ankle braces and a force of 150 N was applied to it. The stress radiographs showed different talar tilts and anterior drawers of each brace. Most ankle braces achieved a satisfying result. It has become obvious that a tight fitting and an anatomically designed shape seem to be favourable. T2 - Constraint of talar tilt and anterior drawer by different ankle braces after the rupture of fibular ligaments KW - Sprunggelenkorthesen KW - fibulare Bandruptur KW - Distorsion des oberen Sprunggelenks KW - ankle sprain KW - rupture of the fibular ligament KW - ankle braces Y1 - 2013 SN - 2193-5785 U6 - https://doi.org/10.3238/oup.2013.0306-0309 VL - 2 IS - 6 SP - 306 EP - 309 PB - Deutscher Ärzte-Verl. CY - Köln ER - TY - JOUR A1 - Koch, Claudia A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Wege, Christian T1 - Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors JF - Nanotheranostics N2 - The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts. Y1 - 2018 U6 - https://doi.org/10.7150/ntno.22114 SN - 2206-7418 VL - 2 IS - 2 SP - 184 EP - 196 PB - Ivyspring CY - Sydney ER - TY - JOUR A1 - Harzheim, Thomas A1 - Mühmel, Marc A1 - Heuermann, Holger T1 - A SFCW harmonic radar system for maritime search and rescue using passive and active tags JF - International Journal of Microwave and Wireless Technologies N2 - This paper introduces a new maritime search and rescue system based on S-band illumination harmonic radar (HR). Passive and active tags have been developed and tested while attached to life jackets and a small boat. In this demonstration test carried out on the Baltic Sea, the system was able to detect and range the active tags up to a distance of 5800 m using an illumination signal transmit-power of 100 W. Special attention is given to the development, performance, and conceptual differences between passive and active tags used in the system. Guidelines for achieving a high HR dynamic range, including a system components description, are given and a comparison with other HR systems is performed. System integration with a commercial maritime X-band navigation radar is shown to demonstrate a solution for rapid search and rescue response and quick localization. KW - Radar KW - microwave measurements KW - harmonic radar KW - harmonic radar tags KW - nonlinear VNA measurements Y1 - 2021 U6 - https://doi.org/10.1017/S1759078721000520 VL - 13 IS - Special Issue 7 SP - 691 EP - 707 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - Poghossian, Arshak A1 - Thust, M. A1 - Schöning, Michael Josef A1 - Müller-Veggian, Mattea A1 - Kordos, P. A1 - Lüth, H. T1 - Cross-sensitivity of a capacitive penicillin sensor combined with a diffusion barrier JF - Sensors and Actuators B. 68 (2000), H. 1-3 Y1 - 2000 SN - 0925-4005 SP - 260 EP - 265 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Brinkmann, D. A1 - Demuth, C. A1 - Poghossian, Arshak T1 - CIP (cleaning-in-place)-suitable „non-glass“ pH sensor based on a Ta2O5-gate EIS structure JF - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale]. Y1 - 2004 SN - 88-7621-282-5 N1 - Eurosensors ; (18, 2004, Roma) SP - 857 EP - 860 CY - Roma ER - TY - JOUR A1 - Poghossian, Arshak A1 - Berndsen, Lars A1 - Lüth, Hans A1 - Schöning, Michael Josef T1 - Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs JF - Proceedings of SPIE. 4560 (2001) Y1 - 2001 SP - 19 EP - 27 ER - TY - JOUR A1 - Staat, Manfred T1 - Sensitivity of and Influences on the Reliability of an HTR-Module Primary Circuit Pressure Boundary JF - Transactions of the 12th International Conference on Structural Mechanics in Reactor Technology (SMiRT-12) / Kussmaul, K. [ed] Y1 - 1993 SN - 0-444-81515-5 N1 - Vol. M, Paper MG10/2 SP - 147 EP - 152 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Stulpe, Werner T1 - Pairwise coexistence of effects versus coexistence JF - Journal of Physics: Conference Series Y1 - 2020 U6 - https://doi.org/10.1088/1742-6596/1638/1/012004 SN - 1742-6596 VL - 1638 IS - 012004 SP - 1 EP - 21 PB - IOP CY - Bristol ER - TY - JOUR A1 - Zhubanova, А. A1 - Mansurov, Z.A. A1 - Digel, Ilya A1 - Saviskaya, I.S. A1 - Akimbekov, Nuraly S. T1 - Designing of Heterogeneous Nanobiocomposites for Biotechnology JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 VL - 59 IS - No 3/1 SP - 89 EP - 93 ER - TY - JOUR A1 - Honarvarfard, Elham A1 - Gamella, Maria A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer JF - Applied Materials Today N2 - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications. KW - Electrolyte–insulator–semiconductor KW - Capacitive field-effect KW - CNOT KW - XOR KW - Enzyme logic gate Y1 - 2017 U6 - https://doi.org/10.1016/j.apmt.2017.08.003 SN - 2352-9407 VL - 9 SP - 266 EP - 270 PB - Elsevier CY - Amsterdam ER -