TY  - JOUR
A1  - Malan, Leone
A1  - Hamer, Mark
A1  - Känel, Roland von
A1  - Kotliar, Konstantin
A1  - Wyk, Roelof D. van
A1  - Lambert, Gavin W.
A1  - Vilser, Walthard
A1  - Ziemssen, Tjalf
A1  - Schlaich, Markus P.
A1  - Smith, Wayne
A1  - Magnusson, Martin
A1  - Wentzel, Annemarie
A1  - Myburgh, Carlien E.
A1  - Steyn, Hendrik S.
A1  - Malan, Nico T.
T1  - Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study
JF  - Cardiovascular Journal of Africa
Y1  - 2020
U6  - http://dx.doi.org/10.5830/CVJA-2020-031
SN  - 1680-0745
VL  - 26
IS  - 31
SP  - 1
EP  - 12
PB  - Clinics Cardive Publishing
CY  - Durbanville
ER  - 
TY  - CHAP
A1  - Voronkova, Eva B.
A1  - Bauer, Svetlana M.
A1  - Kotliar, Konstantin
T1  - Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye
T2  - 2014 International Conference on Computer Technologies in Physical and Engineering Applications :  ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg
Y1  - 2014
SN  - 978-1-4799-5315-8
SP  - 204
EP  - 205
ER  - 
TY  - JOUR
A1  - Angermann, Susanne
A1  - Günthner, Roman
A1  - Hanssen, Henner
A1  - Lorenz, Georg
A1  - Braunisch, Matthias C.
A1  - Steubl, Dominik
A1  - Matschkal, Julia
A1  - Kemmner, Stephan
A1  - Hausinger, Renate
A1  - Block, Zenonas
A1  - Haller, Bernhard
A1  - Heemann, Uwe
A1  - Kotliar, Konstantin
A1  - Grimmer, Timo
A1  - Schmaderer, Christoph
T1  - Cognitive impairment and microvascular function in end-stage renal disease
JF  - International Journal of Methods in Psychiatric Research (MPR)
N2  - Objective
Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels.

Methods
152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions.

Results
In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained.

Conclusion
This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.
KW  - cerebral small vessel disease
KW  - cognitive impairment
KW  - dialysis
KW  - retinal vessels
Y1  - 2022
U6  - http://dx.doi.org/10.1002/mpr.1909
SN  - 1049-8931 (Print)
SN  - 1557-0657 (Online)
VL  - 31
IS  - 2
SP  - 1
EP  - 10
PB  - Wiley
ER  - 
TY  - JOUR
A1  - Feucht, Nikolaus
A1  - Schönbach, Etienne Michael
A1  - Lanzl, Ines
A1  - Kotliar, Konstantin
A1  - Lohmann, Chris Patrick
A1  - Maier, Mathias
T1  - Changes in the foveal microstructure after intravitreal bevacizumab application in patients with retinal vascular disease
JF  - Clinical Ophthalmology
Y1  - 2013
SN  - 1177-5483
VL  - 7
SP  - 173
EP  - 178
PB  - Dove Medical Press
CY  - Auckland, New Zealand
ER  - 
TY  - JOUR
A1  - Neumaier, Felix
A1  - Weiss, Miriam
A1  - Veldeman, Michael
A1  - Kotliar, Konstantin
A1  - Wiesmann, Martin
A1  - Schulze-Steinen, Henna
A1  - Höllig, Anke
A1  - Clusmann, Hans
A1  - Schubert, Gerrit Alexander
A1  - Albanna, Walid
T1  - Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage – preliminary findings from an observational cohort study
JF  - Clinical Neurology and Neurosurgery
N2  - Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.
KW  - constructive alignment
KW  - examination
KW  - long-term retention
KW  - multimodal
KW  - practical learning
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.clineuro.2021.106870
SN  - 0303-8467
VL  - 208
IS  - Article No.: 106870
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
T1  - Can vascular function be assessed by the interpretation of retinal vascular diameter changes?
JF  - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1
Y1  - 2011
SN  - 0146-0404
SP  - 635
EP  - 636
PB  - ARVO
CY  - Rockville, Md.
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Stegaev, V. A.
A1  - Parkhomov, S. D.
T1  - Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A. ; Koshitz, I. N.
JF  - Glaukoma (2004)
Y1  - 2004
N1  - Original in Russisch
SP  - 29
EP  - 39
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Sourjikov, A. V.
A1  - Zaseeva, M. V.
T1  - Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N.
JF  - Glaukoma (2004)
Y1  - 2004
N1  - Original in Russisch
SP  - 66
EP  - 76
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye
JF  - Acta of bioengineering and biomechanics
Y1  - 2002
SN  - 1509-409X
VL  - Vol. 4
IS  - Suppl. 1
SP  - 728
EP  - 729
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Makarov, F. N.
T1  - Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A.
JF  - Glaukoma (2005)
Y1  - 2005
N1  - Original in Russisch
SP  - 41
EP  - 63
PB  - -
ER  -