TY - JOUR A1 - Nguyen-Xuan, H. A1 - Rabczuk, T. A1 - Nguyen-Thoi, T. A1 - Tran, Thanh Ngoc A1 - Nguyen-Thanh, N. T1 - Computation of limit and shakedown loads using a node-based smoothed finite element method JF - International Journal for Numerical Methods in Engineering N2 - This paper presents a novel numerical procedure for computing limit and shakedown loads of structures using a node-based smoothed FEM in combination with a primal–dual algorithm. An associated primal–dual form based on the von Mises yield criterion is adopted. The primal-dual algorithm together with a Newton-like iteration are then used to solve this associated primal–dual form to determine simultaneously both approximate upper and quasi-lower bounds of the plastic collapse limit and the shakedown limit. The present formulation uses only linear approximations and its implementation into finite element programs is quite simple. Several numerical examples are given to show the reliability, accuracy, and generality of the present formulation compared with other available methods. Y1 - 2011 U6 - http://dx.doi.org/10.1002/nme.3317 SN - 1097-0207 VL - 90 IS - 3 SP - 287 EP - 310 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Nguyen, Nhu Huynh A1 - Duong, Minh Tuan A1 - Tran, Thanh Ngoc A1 - Pham, Phu Tinh A1 - Grottke, O. A1 - Tolba, R. A1 - Staat, Manfred T1 - Influence of a freeze–thaw cycle on the stress–stretch curves of tissues of porcine abdominal organs JF - Journal of Biomechanics N2 - The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze–thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze–thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines. KW - Autolysis KW - Decomposition KW - Freeze–thaw process KW - Spleen KW - Liver Y1 - 2012 U6 - http://dx.doi.org/10.1016/j.jbiomech.2012.07.008 SN - 1873-2380 VL - 45 IS - 14 SP - 2382 EP - 2386 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Nguyen, N.-H. A1 - Raatschen, Hans-Jürgen A1 - Staat, Manfred T1 - A hyperelastic model of biological tissue materials in tubular organs Y1 - 2010 N1 - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010. SP - 1 EP - 12 ER - TY - JOUR A1 - Neumaier, Felix A1 - Weiss, Miriam A1 - Veldeman, Michael A1 - Kotliar, Konstantin A1 - Wiesmann, Martin A1 - Schulze-Steinen, Henna A1 - Höllig, Anke A1 - Clusmann, Hans A1 - Schubert, Gerrit Alexander A1 - Albanna, Walid T1 - Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage – preliminary findings from an observational cohort study JF - Clinical Neurology and Neurosurgery N2 - Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH. KW - constructive alignment KW - examination KW - long-term retention KW - multimodal KW - practical learning Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.clineuro.2021.106870 SN - 0303-8467 VL - 208 IS - Article No.: 106870 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Neumaier, Felix A1 - Kotliar, Konstantin A1 - Haeren, Roel Hubert Louis A1 - Temel, Yasin A1 - Lüke, Jan Niklas A1 - Seyam, Osama A1 - Lindauer, Ute A1 - Clusmann, Hans A1 - Hescheler, Jürgen A1 - Schubert, Gerrit Alexander A1 - Schneider, Toni A1 - Albanna, Walid T1 - Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA) JF - Frontiers in Neurology Y1 - 2021 U6 - http://dx.doi.org/10.3389/fneur.2021.659890 VL - 12 SP - 1 EP - 11 PB - Frontiers ER - TY - JOUR A1 - Nam, J. A1 - Arora, D. A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Benkowski, R. A1 - Behr, M. A1 - Pasquali, M. T1 - New computational method in hemolysis analysis for artificial heart pump Y1 - 2010 N1 - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Müller, Wolfram A1 - Jung, Alexander A1 - Ahammer, Helmut T1 - Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example JF - Scientific Reports Y1 - 2017 SN - 2045-2322 U6 - http://dx.doi.org/10.1038/s41598-017-02665-5 VL - 7 IS - Article number 2464 SP - 1 EP - 11 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Murgan, Ilina A1 - Beyer, Sonja A1 - Kotliar, Konstantin A1 - Weber, Lutz A1 - Bechtold-Dalla Pozza, Susanne A1 - Dalla Pozza, Robert A1 - Wegner, Aharon A1 - Sitnikova, Diana A1 - Stock, Konrad A1 - Heemann, Uwe A1 - Schmaderer, Christoph A1 - Baumann, M. T1 - Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents JF - American Journal of Hypertension Y1 - 2013 SN - 1941-7225 VL - 26 IS - 3 SP - 400 EP - 408 PB - Oxford University Press CY - Oxford ER - TY - CHAP A1 - Mueller, Wolfram A1 - Jung, Alexander A1 - Schmölzer, Bernhard ED - Faulhaber, Martin ED - Schobersberger, Wolfgang ED - Schobersberger, Beatrix ED - Sumann, Günther ED - Domej, Wolfgang T1 - Der Einfluss der Höhe über dem Meeresspiegel auf die Flugbahnen im Schispringen T1 - The influence of altitude on the flight paths in ski jumping T2 - Jahrbuch 2015 - Österreichische Gesellschaft für Alpin- und Höhenmedizin Y1 - 2015 SN - 978-3-9501312-5-3 SP - 173 EP - 190 PB - Österreichische Gesellschaft für Alpin- und Höhenmedizin CY - Innsbruck ER - TY - JOUR A1 - Morat, Mareike A1 - Faude, Oliver A1 - Hanssen, Henner A1 - Ludyga, Sebastian A1 - Zacher, Jonas A1 - Eibl, Angi A1 - Albracht, Kirsten A1 - Donath, Lars T1 - Agility Training to Integratively Promote Neuromuscular, Cognitive, Cardiovascular and Psychosocial Function in Healthy Older Adults: A Study Protocol of a One-Year Randomized-Controlled Trial JF - International Journal of Environmental Research and Public Health N2 - Exercise training effectively mitigates aging-induced health and fitness impairments. Traditional training recommendations for the elderly focus separately on relevant physiological fitness domains, such as balance, flexibility, strength and endurance. Thus, a more holistic and functional training framework is needed. The proposed agility training concept integratively tackles spatial orientation, stop and go, balance and strength. The presented protocol aims at introducing a two-armed, one-year randomized controlled trial, evaluating the effects of this concept on neuromuscular, cardiovascular, cognitive and psychosocial health outcomes in healthy older adults. Eighty-five participants were enrolled in this ongoing trial. Seventy-nine participants completed baseline testing and were block-randomized to the agility training group or the inactive control group. All participants undergo pre- and post-testing with interim assessment after six months. The intervention group currently receives supervised, group-based agility training twice a week over one year, with progressively demanding perceptual, cognitive and physical exercises. Knee extension strength, reactive balance, dual task gait speed and the Agility Challenge for the Elderly (ACE) serve as primary endpoints and neuromuscular, cognitive, cardiovascular, and psychosocial meassures serve as surrogate secondary outcomes. Our protocol promotes a comprehensive exercise training concept for older adults, that might facilitate stakeholders in health and exercise to stimulate relevant health outcomes without relying on excessively time-consuming physical activity recommendations. KW - agility KW - prevention KW - healthy aging KW - community dwelling KW - psychosocial Y1 - 2020 U6 - http://dx.doi.org/10.3390/ijerph17061853 SN - 1660-4601 VL - 17 IS - 6 SP - 1 EP - 14 PB - MDPI CY - Basel ER -