TY  - CHAP
A1  - Bayer, Robin
A1  - Hescheler, Jürgen
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Treating arterial hypertension in a cell culture well
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW
N2  - Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the “Deutsche Bluthochdruck Liga” this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model.
In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology.
Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - http://dx.doi.org/10.17185/duepublico/48750
SP  - 5
EP  - 6
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - THES
A1  - Föckler, Nicole
T1  - Biomarker zur Prognose von Frühgeburten : ein biomedizintechnischer Ansatz
Y1  - 2016
U6  - http://dx.doi.org/10.4126/FRL01-006401575
N1  - Dissertation, Köln, Universität zu Köln, 2016
PB  - Deutsche Zentralbibliothek für Medizin
CY  - Köln
ER  - 
TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Staat, Manfred
T1  - A computational study of organ relocation after laparoscopic pectopexy to repair posthysterectomy vaginal vault prolapse
JF  - Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
Y1  - 2019
U6  - http://dx.doi.org/10.1080/21681163.2019.1670095
SN  - 2168-1171
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - THES
A1  - Bassam Abduljabbar, Rasha
T1  - Physikalisch-chemische Steuerung der Proteinstabilität in biologischen Systemen
T1  - Physico-chemical management of protein stability in biological systems
Y1  - 2015
ER  - 
TY  - THES
A1  - Goßmann, Matthias
T1  - Entwicklung eines autokontraktilen Herzmuskelmodells zur funktionalen Medikamenten- und Toxinforschung
Y1  - 2015
N1  - Duisburg, Essen, Universität Duisburg-Essen, Diss., 2015
PB  - Universitätsbibliothek Duisburg-Essen
CY  - Duisburg ; Essen
ER  - 
TY  - THES
A1  - Seifarth, Volker
T1  - Ureteral tissue engineering : development of a bioreactor system and subsequent characterization of the generated biohybrids
Y1  - 2015
N1  - Duisburg, Essen, Universität Duisburg-Essen, Diss., 2015
PB  - Universitätsbibliothek Duisburg-Essen
CY  - Duisburg ; Essen
ER  - 
TY  - THES
A1  - Oflaz, Hakan
T1  - Entwicklung eines Prototypen zur Prognose von Frühgeburten : ein biomedizintechnischer Ansatz
Y1  - 2012
U6  - http://dx.doi.org/10.4126/38m-004639208
N1  - Köln, Univ., Diss., 2012
PB  - Deutsche Zentralbibliothek für Medizin
CY  - Köln
ER  - 
TY  - THES
A1  - Behbahani, Mehdi
T1  - Modeling and Simulation of Shear-Dependent Platelet Reactions in Blood Vessels and Blood-Contacting Medical Devices
Y1  - 2011
SN  - 978-3-8439-0134-5
PB  - Verlag Dr. Hut
CY  - München
ER  - 
TY  - THES
A1  - Kurulgan Demirci, Eylem
T1  - The effect of rhAPC on contractile tension : an in-vitro sepsis model of cardiomyocytes and endothelial cells
T1  - Der Effekt von rhAPC auf die zelluläre Kontraktionskraft : ein In-vitro-Sepsismodell für Kardiomyozyten und Endothelzellen
Y1  - 2012
N1  - Aachen, Techn. Hochsch., Diss., 2012
ER  - 
TY  - THES
A1  - Trzewik, Jürgen
T1  - Experimental analysis of biaxial mechanical tension in cell monolayers and cultured three-dimensional tissues: the celldrum technology
Y1  - 2007
N1  - Zugl.: Ilmenau, Techn. Univ., Diss., 2007
PB  - Univeristätsverlg Ilmenau
CY  - Ilmenau
ER  -