TY - JOUR A1 - Schwabedal, Justus T. C. A1 - Sippel, Daniel A1 - Brandt, Moritz D. A1 - Bialonski, Stephan T1 - Automated Classification of Sleep Stages and EEG Artifacts in Mice with Deep Learning N2 - Sleep scoring is a necessary and time-consuming task in sleep studies. In animal models (such as mice) or in humans, automating this tedious process promises to facilitate long-term studies and to promote sleep biology as a data-driven f ield. We introduce a deep neural network model that is able to predict different states of consciousness (Wake, Non-REM, REM) in mice from EEG and EMG recordings with excellent scoring results for out-of-sample data. Predictions are made on epochs of 4 seconds length, and epochs are classified as artifactfree or not. The model architecture draws on recent advances in deep learning and in convolutional neural networks research. In contrast to previous approaches towards automated sleep scoring, our model does not rely on manually defined features of the data but learns predictive features automatically. We expect deep learning models like ours to become widely applied in different fields, automating many repetitive cognitive tasks that were previously difficult to tackle. Y1 - 2018 U6 - http://dx.doi.org/10.48550/arXiv.1809.08443 ER - TY - JOUR A1 - Teumer, T. A1 - Capitain, C. A1 - Ross-Jones, J. A1 - Tippkötter, Nils A1 - Rädle, M. A1 - Methner, F.-J. T1 - In-line Haze Monitoring Using a Spectrally Resolved Back Scattering Sensor JF - BrewingScience N2 - In the present work an optical sensor in combination with a spectrally resolved detection device for in-line particle-size-monitoring for quality control in beer production is presented. The principle relies on the size and wavelength dependent backscatter of growing particles in fluids. Measured interference structures of backscattered light are compared with calculated theoretical values, based on Mie-Theory, and fitted with a linear least square method to obtain particle size distributions. For this purpose, a broadband light source in combination with a process-CCD-spectrometer (charge ? coupled device spectrometer) and process adapted fiber optics are used. The goal is the development of an easy and flexible measurement device for in-line-monitoring of particle size. The presented device can be directly installed in product fill tubes or vessels, follows CIP- (cleaning in place) and removes the need of sample taking. A proof of concept and preliminary results, measuring protein precipitation, are presented. Y1 - 2018 SN - 1613-2041 VL - 71 IS - 5/6 SP - 49 EP - 55 PB - Fachverlag Hans Carl CY - Nürnberg ER - TY - CHAP A1 - Duwe, A. A1 - Tippkötter, Nils A1 - Ulber, R. T1 - Lignocellulose-Biorefinery: Ethanol-Focused T2 - Biorefineries N2 - The development prospects of the world markets for petroleum and other liquid fuels are diverse and partly contradictory. However, comprehensive changes for the energy supply of the future are essential. Notwithstanding the fact that there are still very large deposits of energy resources from a geological point of view, the finite nature of conventional oil reserves is indisputable. To reduce our dependence on oil, the EU, the USA, and other major economic zones rely on energy diversification. For this purpose, alternative materials and technologies are being sought, and is most obvious in the transport sector. The objective is to progressively replace fossil fuels with renewable and more sustainable fuels. In this respect, biofuels have a pre-eminent position in terms of their capability of blending with fossil fuels and being usable in existing cars without substantial modification. Ethanol can be considered as the primary renewable liquid fuel. In this chapter enzymes, micro-organisms, and processes for ethanol production based on renewable resources are described. KW - Bioethanol KW - Biorefinery KW - Lignocellulose feedstook Y1 - 2018 U6 - http://dx.doi.org/10.1007/10_2016_72 N1 - Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE,volume 166) SP - 177 EP - 215 PB - Springer CY - Cham ER - TY - RPRT A1 - Tippkötter, Nils T1 - Lokale Vorbehandlung nachwachsender Rohstoffe für Bioraffinerien (BioSats) : Schlussbericht zum Vorhaben : Laufzeit: 01.03.2012 bis 30.04.2017 Y1 - 2018 U6 - http://dx.doi.org/10.2314/GBV:1024204243 ER - TY - JOUR A1 - Fissabre, Anke A1 - Wilson, Ariane T1 - Der Turm mit zehn Spornen – Ein in Monthoiron gebauter Entwurf von Leonardo Da Vinci? JF - In situ: Zeitschrift für Architekturgeschichte Y1 - 2018 SN - 1866-959X N1 - gedruckt in der Bereichsbibliothek Bayernallee vorhanden. Signatur 13 Z 959-2018 IS - 1 SP - 65 EP - 82 PB - Wernersche Verlagsgesellschaft CY - Worms ER - TY - CHAP A1 - Blome, Hans-Joachim T1 - Über die kulturelle Bedeutung der Raumfahrt T2 - Überleben im Weltraum. Auf dem Weg zu neuen Grenzen. 21. Berliner Kolloquium der Daimler und Benz Stiftung 24. Mai 2017 Y1 - 2018 SP - 5 EP - 5 ER - TY - BOOK A1 - Jochim, Haldor E. A1 - Lademann, Frank T1 - Planung von Bahnanlagen: Grundlagen - Planung - Berechnung Y1 - 2018 SN - 978-3-446-44220-7 U6 - http://dx.doi.org/10.3139/9783446448940 PB - Fachbuchverlag Leipzig im Carl Hanser Verlag CY - München ET - 2., aktualisierte und erweiterte Auflage ER - TY - JOUR A1 - de Blois, Eric A1 - de Zanger, Rory M. S. A1 - Paulßen, Elisabeth A1 - Sze Chan, Ho A1 - Breeman, Wouter A. P. T1 - Semi-automated system for concentrating 68Ga-eluate to obtain high molar and volume concentration of 68Ga-Radiopharmaca for preclinical applications JF - Nuclear Medicine and Biology N2 - 68Ga-radiopharmaceuticals are common in the field of Nuclear Medicine to visualize receptor-mediated processes. In contrast to straightforward labeling procedures for clinical applications, preclinical in vitro and in vivo applications are hampered for reasons like e.g. volume restriction, activity concentration, molar activity and osmolality. Therefore, we developed a semiautomatic system specifically to overcome these problems. A difficulty appeared unexpectedly, as intrinsic trace metals derived from eluate (Zn, Fe and Cu) are concentrated as well in amounts that influence radiochemical yield and thus lower molar activity. Y1 - 2018 U6 - http://dx.doi.org/10.1016/j.nucmedbio.2018.06.006 VL - 64-65 SP - 16 EP - 21 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Keutmann, Sabine A1 - Staat, Manfred A1 - Laack, Walter van T1 - Untersuchung der thermischen Auswirkung von therapeutischem Ultraschall N2 - Zusammenfassung: In der Orthopädie zählt der therapeutische Ultraschall als Mittel zur Prävention und Therapiebegleitung. Er hat mechanische, thermische und physiko-chemische Auswirkungen auf den menschlichen Körper. Um mehr Erkenntnisse über die thermischen Auswirkungen zu erlangen, wurden Versuche an einem Hydrogel-Phantom und an Probanden durchgeführt. Dabei entstand eine signifikante Erwärmung des Gewebes, welche beim Probandenversuch an der Oberfläche und beim Hydrogelversuch in der Tiefe gemessen wurde. Summary: In orthopaedics, therapeutic ultrasound is a tool of prevention and therapy support. It has mechanical, thermal and physico-chemical effects on the human body. Tests with a hydrogel phantom and with human probands have been performed in order to obtain more knowledge about their thermal effects. Both tests measured temperature increases in cell tissue, on the surface with the human proband test and in depth with the hydrogel phantom test. T2 - Research about the thermal effects of therapeutic ultrasound Y1 - 2018 SN - 2193-5793 SN - 2193-5785 (Druckausgabe) VL - 7 IS - 10 SP - 518 EP - 522 PB - Deutscher Ärzte-Verl. CY - Köln ER - TY - JOUR A1 - Olbertz, Klaus T1 - Überwachung von Arbeitnehmern als Ausdruck von Compliance - Grundsätze sowie Zulässigkeit und Grenzen einzelner Maßnahmen JF - NWB - Steuer- und Wirtschaftsrecht Y1 - 2018 SN - 1860-9449 IS - 21 SP - 1547 EP - 1555 PB - NWB-Verl. CY - Herne ER -