TY - JOUR A1 - Horstmann, Marie-Therese A1 - Bialonski, Stephan A1 - Noenning, Nina A1 - Mai, Heinke A1 - Prusseit, Jens A1 - Wellmer, Jörg A1 - Hinrichs, Hermann A1 - Lehnertz, Klaus T1 - State dependent properties of epileptic brain networks: Comparative graph–theoretical analyses of simultaneously recorded EEG and MEG JF - Clinical Neurophysiology N2 - Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks. Y1 - 2010 U6 - https://doi.org/10.1016/j.clinph.2009.10.013 SN - 1388-2457 VL - 121 IS - 2 SP - 172 EP - 185 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Lehnertz, Klaus A1 - Mormann, Florian A1 - Osterhage, Hannes A1 - Andy, Müller A1 - Prusseit, Jens A1 - Chernihovskyi, Anton A1 - Staniek, Matthäus A1 - Krug, Dieter A1 - Bialonski, Stephan A1 - Elger, Christian E. T1 - State-of-the-art of seizure prediction JF - Journal of Clinical Neurophysiology Y1 - 2007 U6 - https://doi.org/10.1097/WNP.0b013e3180336f16 SN - 1537-1603 VL - 24 IS - 2 SP - 147 EP - 153 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. T1 - Stati isomerici nei nuclei ¹⁸⁹,¹⁹¹,¹⁹³ Au JF - Bollettino della Società Italiana di Fisica Y1 - 1976 SN - 0037-8801 N1 - Trento, Italia, 28. Settembre - 2. Ottobre 1976 VL - 1976 SP - 56 PB - Zanichelli CY - Bologna ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel A1 - Thiele, Jan Philipp T1 - Statistical inference for L²-distances to uniformity JF - Computational Statistics N2 - The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study. KW - Integrated empirical distribution (survival) function KW - Goodness-of-fit tests for uniformity KW - Numerical inversion of Laplace transforms KW - Coverage probability KW - Equivalence test Y1 - 2018 U6 - https://doi.org/10.1007/s00180-018-0820-0 SN - 1613-9658 VL - 2018 IS - 33 SP - 1863 EP - 1896 PB - Springer CY - Berlin ER - TY - JOUR A1 - Heinrich, U. A1 - Blum, A. A1 - Bussmann, N. A1 - Engels, R. A1 - Kemmerling, G. A1 - Weber, S. A1 - Ziemons, Karl T1 - Statistical studies on the light output and energy resolution of small LSO single crystals with different surface treatments combined with various reflector materials JF - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment N2 - The optimization of light output and energy resolution of scintillators is of special interest for the development of high resolution and high sensitivity PET. The aim of this work is to obtain statistically reliable results concerning optimal surface treatment of scintillation crystals and the selection of reflector material. For this purpose, raw, mechanically polished and etched LSO crystals (size 2×2×10 mm3) were combined with various reflector materials (Teflon tape, Teflon matrix, BaSO4) and exposed to a 22Na source. In order to ensure the statistical reliability of the results, groups of 10 LSO crystals each were measured for all combinations of surface treatment and reflector material. Using no reflector material the light output increased up to 551±35% by mechanical polishing the surface compared to 100±5% for raw crystals. Etching the surface increased the light output to 441±29%. The untreated crystals had an energy resolution of 24.6±4.0%. By mechanical polishing the surface it was possible to achieve an energy resolution of 13.2±0.8%, by etching of 14.8±0.7%. In combination with BaSO4 as reflector material the maximum increase of light output has been established to 932±57% for mechanically polished and 895±61% for etched crystals. The combination with BaSO4 also caused the best improvement of the energy resolution up to 11.6±0.2% for mechanically polished and 12.2±0.3% for etched crystals. Relating to the light output there was no significant statistical difference between the two surface treatments in combination with BaSO4. In contrast to this, the statistical results of the energy resolution have shown the combination of mechanical polishing and BaSO4 as the optimum. Y1 - 2002 SN - 0168-9002 N1 - Proceedings of the 6th International Conference on Inorganic Scin tillators and their Use in Scientific and Industrial Applications VL - 486 IS - 1-2 SP - 60 EP - 66 ER - TY - JOUR A1 - Laack, Walter van A1 - Refisch, A. T1 - Stellenwert der Kniegelenksarthroskopie aus diagnostischer und therapeutischer Sicht JF - Aktuelle Ergebnisse der Osteologie : Timmendorfer Strand, 21. - 23. November 1985 / hrsg. von P. Dietsch Y1 - 1986 SN - 3-11-011147-0 N1 - Osteologia ; 1 PB - de Gruyter CY - Berlin ER - TY - BOOK A1 - Artmann, Gerhard T1 - Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds. Y1 - 2011 SN - 978-3-642-11864-7 PB - Springer CY - Berlin [u.a.] ER - TY - BOOK A1 - Laack, Walter van T1 - Sterben und Tod aus wissenschaftlicher Sicht - dying and death from a scientific point of view Y1 - 2018 SN - 978-3-936624-41-0 PB - van Laack GmbH CY - Aachen ER - TY - BOOK A1 - Kaminsky, Radoslav A1 - Kallweit, Stephan A1 - Weber, Hans-Joachim A1 - Simons, Antoine A1 - Verdonck, Pascal T1 - Stereo high speed PIV measurements behind two different artificial heart valves Y1 - 2006 N1 - International Symposium on Applications of Laser Techniques to Fluid Mechanics <13, 2006, Lisboa> ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Sterilization of Objects, Products, and Packaging Surfaces and Their Characterization in Different Fields of Industry: The Status in 2020 JF - physica status solidi (a) applications and materials science N2 - The treatment method to deactivate viable microorganisms from objects or products is termed sterilization. There are multiple forms of sterilization, each intended to be applied for a specific target, which depends on—but not limited to—the thermal, physical, and chemical stability of that target. Herein, an overview on the currently used sterilization processes in the global market is provided. Different sterilization techniques are grouped under a category that describes the method of treatment: radiation (gamma, electron beam, X-ray, and ultraviolet), thermal (dry and moist heat), and chemical (ethylene oxide, ozone, chlorine dioxide, and hydrogen peroxide). For each sterilization process, the typical process parameters as defined by regulations and the mode of antimicrobial activity are summarized. Finally, the recommended microorganisms that are used as biological indicators to validate sterilization processes in accordance with the rules that are established by various regulatory agencies are summarized. KW - bioburdens KW - sterility tests KW - sterilization efficacy KW - sterilization methods KW - validation methods Y1 - 2021 U6 - https://doi.org/10.1002/pssa.202000732 SN - 1862-6319 N1 - Corresponding author: Michael J. Schöning VL - 218 IS - 13 PB - Wiley-VCH CY - Weinheim ER -