TY  - JOUR
A1  - Seifarth, Volker
A1  - Schehl, D.
A1  - Linder, Peter
A1  - Gossmann, Matthias
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Porst, Dariusz
A1  - Preiß, C.
A1  - Kayser, Peter
A1  - Pack, O.
A1  - Temiz Artmann, Aysegül
T1  - Ureplace: development of a bioreactor for in vitro culturing of cell seeded tubular vessels on collagen scaffolds
N2  - The demand of replacements for inoperable organs exceeds the amount of available organ transplants. Therefore, tissue engineering developed as a multidisciplinary field of research for autologous in-vitro organs. Such three dimensional tissue constructs request the application of a bioreactor. The UREPLACE bioreactor is used to grow cells on tubular collagen scaffolds OPTIMAIX Sponge 1 with a maximal length of 7 cm, in order to culture in vitro an adequate ureter replacement. With a rotating unit, (urothelial) cells can be placed homogeneously on the inner scaffold surface. Furthermore, a stimulation is combined with this bioreactor resulting in an orientation of muscle cells. These culturing methods request a precise control of several parameters and actuators. A combination of a LabBox and the suitable software LabVision is used to set and conduct parameters like rotation angles, velocities, pressures and other important cell culture values. The bioreactor was tested waterproof successfully. Furthermore, the temperature controlling was adjusted to 37 °C and the CO2 - concentration regulated to 5 %. Additionally, the pH step responses of several substances showed a perfect functioning of the designed flow chamber. All used software was tested and remained stable for several days.
KW  - Tissue Engineering
KW  - Bioreaktor
KW  - Organkultur
KW  - Harnleiter
Y1  - 2011
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Delle, L.
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Zang, Werner
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Electrochemical sensor array for bioprocess monitoring
JF  - Electrochimica Acta (2011)
Y1  - 2011
VL  - 56
IS  - 26
SP  - 9673
EP  - 9678
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kurulgan Demirci, Eylem
A1  - Demirci, T.
A1  - Trzewik, Jürgen
A1  - Linder, Peter
A1  - Karakulah, G.
A1  - Artmann, Gerhard
A1  - Sakizli, M.
A1  - Temiz Artmann, Aysegül
T1  - Genome-Wide Gene Expression Analysis of NIH 3T3 Cell Line Under Mechanical Stimulation
JF  - Cellular and molecular bioengineering. 4 (2011), H. 1
Y1  - 2011
SN  - 1865-5025
SP  - 46
EP  - 55
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Huck, Christina
A1  - Jolly, Christina
A1  - Wagner, Patrick
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen
JF  - Procedia Engineering. 25 (2011)
Y1  - 2011
SN  - 1877-7058
N1  - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece
SP  - 1161
EP  - 1164
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Gun, Jenny
A1  - Gutkin, Vitaly
A1  - Lev, Ovadia
A1  - Boyen, Hans-Gerd
A1  - Saitner, Marc
A1  - Wagner, Patrick
A1  - Olieslaeger, Marc D´
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices
JF  - Journal of Physical Chemistry C. 115 (2011), H. 11
Y1  - 2011
SN  - 1932-7455
SP  - 4439
EP  - 4445
PB  - American Cemical Society
CY  - Washington, DC
ER  -