TY - CHAP A1 - Klocke, Martina T1 - Projektmodul im Bachelorstudiengang Maschinenbau und Mechatronik T2 - VDI-Workshop Projektorientiertes und problem-basiertes Lernen (PBL) in der Ingenieurausbildung Y1 - 2012 N1 - 25 Folien zum eingeladenen Vortrag beim VDI-Workshop. Darmstadt, 22./23.11.2012 SP - 1 EP - 25 ER - TY - CHAP A1 - Knackstedt, Ralf A1 - Eggert, Mathias A1 - Fleischer, Stefan T1 - The Legal Perspective on Business to Government Reporting - A Conceptual Modeling Approach and Its Application in the Financial Sector T2 - 45th Hawaii International Conference on System Sciences 2012 Y1 - 2012 SN - 978-0-7695-4525-7 U6 - http://dx.doi.org/10.1109/HICSS.2012.576 SP - 2309 EP - 2318 ER - TY - JOUR A1 - Knüppel, Mark ED - Federmann, Rudolf ED - Kußmaul, Heinz ED - Müller, Stefan T1 - Außerbilanzielle Korrekturen JF - Handbuch der Bilanzierung online Y1 - 2012 SN - 0172-0392 SP - Artikel HI 1380074 PB - Haufe CY - Freiburg ER - TY - JOUR A1 - Kobus, Thiele A1 - Bitz, Andreas A1 - Uden, Mark J. van A1 - Lagemaat, Miram W. A1 - Rothgang, Eva A1 - Orzada, Stephan A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - In vivo 31P MR spectroscopic imaging of the human prostate at 7 T: safety and feasibility JF - Magnetic Resonance in Medicine N2 - 31P MR spectroscopic imaging of the human prostate provides information about phosphorylated metabolites that could be used for prostate cancer characterization. The sensitivity of a magnetic field strength of 7 T might enable 3D 31P MR spectroscopic imaging with relevant spatial resolution in a clinically acceptable measurement time. To this end, a 31P endorectal coil was developed and combined with an eight-channel 1H body-array coil to relate metabolic information to anatomical location. An extensive safety validation was performed to evaluate the specific absorption rate, the radiofrequency field distribution, and the temperature distribution of both coils. This validation consisted of detailed Finite Integration Technique simulations, confirmed by MR thermometry and Burn:x-wiley:07403194:media:MRM24175:tex2gif-stack-1 measurements in a phantom and in vivo temperature measurements. The safety studies demonstrated that the presence of the 31P endorectal coil had no influence on the specific absorption rate levels and temperature distribution of the external eight-channel 1H array coil. To stay within a 10 g averaged local specific absorption rate of 10 W/kg, a maximum time-averaged input power of 33 W for the 1H array coil was allowed. For transmitting with the 31P endorectal coil, our safety limit of less than 1°C temperature increase in vivo during a 15-min MR spectroscopic imaging experiment was reached at a time-averaged input power of 1.9 W. With this power setting, a second in vivo measurement was performed on a healthy volunteer. Using adiabatic excitation, 3D 31P MR spectroscopic imaging produced spectra from the entire prostate in 18 min with a spatial resolution of 4 cm3. The spectral resolution enabled the separate detection of phosphocholine, phosphoethanolamine, inorganic phosphate, and other metabolites that could play an important role in the characterization of prostate cancer. Y1 - 2012 U6 - http://dx.doi.org/10.1002/mrm.24175 SN - 1522-2594 VL - 68 IS - 6 SP - 1683 EP - 1695 PB - Wiley-Liss CY - New York ER - TY - THES A1 - Kotliar, Konstantin T1 - Pathophysiologische Beurteilung und hämodynamische Analyse von mikrostrukturellen Veränderungen des retinalen Gefäßlängsschnittsprofils Y1 - 2012 N1 - Moskau, Habil.-Schr. ,Russ. Univ., Med. Fakultät, 2012. Originaltitel in Russisch. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Hanssen, Henner A1 - Eberhardt, Karla A1 - Vilser, Walthard A1 - Halle, Martin A1 - Heemann, Uwe A1 - Schmidt-Trucksäss, Arno A1 - Baumann, Marcus T1 - Does increased blood pressure rather than aging influence retinal pulse wave velocity? JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself. Methods: A total of 12 young 25.5-year-old (24.0–28.8) [median(1st quartile–3rd quartile)] and 12 senior 68.5-year-old (63.8–71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8–65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5–35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated. Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280–500] RU/s) and in validated healthy seniors (400 [320–510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains. Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV. Y1 - 2012 U6 - http://dx.doi.org/10.1167/iovs.11-8815 SN - 0146-0404 VL - 53 IS - 4 SP - 2119 EP - 2126 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kroll-Ludwigs, Kathrin T1 - Ein optionales Vertragsrecht für Europa: Motor oder Hemmnis für den Binnenmarkt? JF - GPR : Zeitschrift für Gemeinschaftsprivatrecht Y1 - 2018 U6 - http://dx.doi.org/10.1515/gpr.2012.9.4.181 SN - 2193-9519 VL - 9 IS - 4 SP - 181 EP - 188 PB - Verlag Dr. Otto Schmidt CY - Köln ER - TY - CHAP A1 - Kuhlmann, Wolfram A1 - Butenweg, Christoph A1 - Meskouris, Konstantin A1 - Kempen, Thomas T1 - Simulation des Tragverhaltens des Aachener Doms im Erdbebenfall T2 - Die karolingische Pfalzkapelle in Aachen : Material, Bautechnik, Restaurierung. (Arbeitshefte der rheinischen Denkmalpflege ; 78) Y1 - 2012 SN - 978-3-88462-325-1 SP - 237 EP - 248 PB - Wernersche Verlags-Gesellschaft CY - Worms ER - TY - CHAP A1 - Kuhnhenne, Markus A1 - Döring, Bernd A1 - Pyschny, Dominik A1 - Feldmann, Markus T1 - Energy efficient sandwich construction T2 - Proceedings of the VI International Congress on Architectural Envelopes : 20.6. - 22.6.2012, San Sebastian, Spain Y1 - 2012 SP - 277 EP - 285 PB - ICAE ER - TY - THES A1 - Kurulgan Demirci, Eylem T1 - The effect of rhAPC on contractile tension : an in-vitro sepsis model of cardiomyocytes and endothelial cells T1 - Der Effekt von rhAPC auf die zelluläre Kontraktionskraft : ein In-vitro-Sepsismodell für Kardiomyozyten und Endothelzellen Y1 - 2012 N1 - Aachen, Techn. Hochsch., Diss., 2012 ER -