TY  - JOUR
A1  - Timme, Michael
T1  - Rechtsgeschichte als methodischer Zugang zu einem Recht der Gemeinschaftsgüter
JF  - Methodische Zugänge zu einem Recht der Gemeinschaftsgüter. Christoph Engel (Hrsg.)
Y1  - 1998
SN  - 3-7890-5530-1
N1  - Common goods ; Vol. 1
SP  - 143
EP  - 157
PB  - Nomos-Verl.-Ges.
CY  - Baden-Baden
ER  - 
TY  - JOUR
A1  - Timme, Michael
T1  - "Der widerwillige Verkäufer" - Klausur aus dem Zivilrecht
JF  - Juristische Arbeitsblätter (1998)
Y1  - 1998
SP  - 31
EP  - 41
ER  - 
TY  - JOUR
A1  - Timme, Michael
T1  - Rücktritt vom Kauf einer gestohlenen Sache
JF  - Juristische Schulung (1998)
Y1  - 1998
SP  - 0
EP  - 15
ER  - 
TY  - JOUR
A1  - Timme, Michael
T1  - Das Konkurrenzverhältnis von § 306 und § 538 BGB
Y1  - 1998
N1  - Neue Zeitschrift für Mietrecht
SP  - 396
EP  - 398
ER  - 
TY  - JOUR
A1  - Timme, Michael
T1  - Die abstrakte Berechnung des Käuferschadens
JF  - Juristische Arbeitsblätter (1998)
Y1  - 1998
SP  - 895
EP  - 900
ER  - 
TY  - JOUR
A1  - Timme, Michael
A1  - Voß, Wulf Eckart
T1  - Anmerkung zu BGH, Urteil vom 18.6.1997 (Mietrecht)
JF  - Juristenzeitung (1998)
Y1  - 1998
SP  - 304
EP  - 306
ER  - 
TY  - BOOK
A1  - Wahle, Michael
T1  - Grundlagen der Maschinen- und Strukturdynamik. - (Höhere Technische Mechanik ; 2)
Y1  - 1998
SN  - 3-89653-391-6
N1  - 2. Aufl.
PB  - Verl. Mainz
CY  - Aachen
ER  - 
TY  - BOOK
A1  - Wahle, Michael
T1  - Dynamik : Kinematik und Kinetik
Y1  - 1998
SN  - 3-89653-390-8
N1  - Die zwei Bände der ersten Auflage in einem Band.
PB  - Verl. Mainz
CY  - Aachen
ET  - 2. Aufl.
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
T1  - Applied physics of compressible and incompressible fluids
T2  - Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo
Y1  - 1998
SN  - 978-94-010-6306-7
SP  - 63
EP  - 84
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Weckesser, Martin
A1  - Grießmeier, Martin
A1  - Schmidt, Daniela
A1  - Sonnenberg, Frank
A1  - Ziemons, Karl
A1  - Kemna, Lars
A1  - Holschbach, Marcus
A1  - Langen, Karl-J.
A1  - Müller-Gärtner, Hans-W.
T1  - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent
JF  - European Journal of Nuclear Medicine
N2  - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Y1  - 1998
SN  - 1619-7089
VL  - 25
IS  - 2
SP  - 150
EP  - 156
ER  -