TY - BOOK A1 - Laack, Walter van T1 - Sterben und Tod aus wissenschaftlicher Sicht - dying and death from a scientific point of view Y1 - 2018 SN - 978-3-936624-41-0 PB - van Laack GmbH CY - Aachen ER - TY - JOUR A1 - Lapitan, Denis G. A1 - Rogatkin, Dmitrii A. A1 - Persheyev, Sydulla K. A1 - Kotliar, Konstantin T1 - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter JF - Biomedizinische Technik N2 - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise. Y1 - 2018 U6 - http://dx.doi.org/10.1515/bmt-2017-0060 SN - 0013-5585 VL - 63 IS - 4 SP - 439 EP - 444 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Laura, C.O. A1 - Drechsler, Klaus A1 - Erdt, M. A1 - Wesarg, S. A1 - Bale, R. T1 - Intervention assessment tool for primary tumors in the liver JF - Current Directions in Biomedical Engineering N2 - After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm. Y1 - 2018 U6 - http://dx.doi.org/10.1515/cdbme-2018-0081 SN - 2364-5504 VL - 4 IS - 1 SP - 337 EP - 340 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena T1 - Optimizing the design and control of decentralized water supply systems – a case-study of a hotel building T2 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization N2 - To increase pressure to supply all floors of high buildings with water, booster stations, normally consisting of several parallel pumps in the basement, are used. In this work, we demonstrate the potential of a decentralized pump topology regarding energy savings in water supply systems of skyscrapers. We present an approach, based on Mixed-Integer Nonlinear Programming, that allows to choose an optimal network topology and optimal pumps from a predefined construction kit comprising different pump types. Using domain-specific scaling laws and Latin Hypercube Sampling, we generate different input sets of pump types and compare their impact on the efficiency and cost of the total system design. As a realistic application example, we consider a hotel building with 325 rooms, 12 floors and up to four pressure zones. KW - Engineering optimization KW - Energy efficiency KW - Water KW - Pump System KW - Latin Hypercube Sampling Y1 - 2018 SN - 978-3-319-97773-7 SN - 978-3-319-97772-0 U6 - http://dx.doi.org/10.1007/978-3-319-97773-7_107 N1 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization. 17-19 September 2018. Lisboa, Portugal SP - 1241 EP - 1252 PB - Springer CY - Cham ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Technical Operations Research (TOR) - Algorithms, not Engineers, Design Optimal Energy Efficient and Resilient Cooling Systems T2 - FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems N2 - The overall energy efficiency of ventilation systems can be improved by considering not only single components, but by considering as well the interplay between every part of the system. With the help of the method "TOR" ("Technical Operations Research"), which was developed at the Chair of Fluid Systems at TU Darmstadt, it is possible to improve the energy efficiency of the whole system by considering all possible design choices programmatically. We show the ability of this systematic design approach with a ventilation system for buildings as a use case example. Based on a Mixed-Integer Nonlinear Program (MINLP) we model the ventilation system. We use binary variables to model the selection of different pipe diameters. Multiple fans are model with the help of scaling laws. The whole system is represented by a graph, where the edges represent the pipes and fans and the nodes represents the source of air for cooling and the sinks, that have to be cooled. At the beginning, the human designer chooses a construction kit of different suitable fans and pipes of different diameters and different load cases. These boundary conditions define a variety of different possible system topologies. It is not possible to consider all topologies by hand. With the help of state of the art solvers, on the other side, it is possible to solve this MINLP. Next to this, we also consider the effects of malfunctions in different components. Therefore, we show a first approach to measure the resilience of the shown example use case. Further, we compare the conventional approach with designs that are more resilient. These more resilient designs are derived by extending the before mentioned model with further constraints, that consider explicitly the resilience of the overall system. We show that it is possible to design resilient systems with this method already in the early design stage and compare the energy efficiency and resilience of these different system designs. Y1 - 2018 N1 - International Conference on Fan Noise, Aerodynamics, Applications and Systems 18-20.04.2018 Darmstadt, Deutschland SP - 1 EP - 12 ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming T2 - Operations Research Proceedings 2017 N2 - The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design. KW - Engineering optimization KW - Global optimization KW - Energy efficiency KW - Water KW - Network Y1 - 2018 SN - 978-3-319-89919-0 U6 - http://dx.doi.org/10.1007/978-3-319-89920-6_63 PB - Springer CY - Cham ER - TY - JOUR A1 - Lind, Thorsten Patric T1 - Neues zur Geschäftsführerhaftung nach § 64 GmbHG - Zugleich Anmerkung zu BGH vom 19.12.2017 - II ZR 88/16, DB 2018 S. 307, und vom 04.07.2017 - II ZR 319/15, DB 2017 S. 1959 - JF - Der Betrieb Y1 - 2018 SN - 0005-9935 IS - 17 SP - 1003 EP - 1008 PB - Fachmedien Otto Schmidt CY - Düsseldorf ER - TY - GEN A1 - Lind, Thorsten Patric T1 - Antrag auf Löschung von Insolvenzvermerken bei Insolvenz eines GbR-Gesellschafters T2 - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring Y1 - 2018 SN - 1611-1095 N1 - BGH Beschl. v. 13.7.2017 – V ZB 136/16, LMK 2018, 401892 ER - TY - CHAP A1 - Ludowicy, Jonas A1 - Rings, René A1 - Finger, Felix A1 - Braun, Carsten T1 - Sizing Studies of Light Aircraft with Serial Hybrid Propulsion Systems T2 - Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen Y1 - 2018 ER - TY - CHAP A1 - Ludowicy, Jonas A1 - Rings, René A1 - Finger, Felix A1 - Braun, Carsten T1 - Sizing Studies of Light Aircraft with Parallel Hybrid Propulsion Systems T2 - Deutscher Luft- und Raumfahrtkongress 2018 Y1 - 2018 U6 - http://dx.doi.org/10.25967/480227 ER -