TY  - JOUR
A1  - Terstegge, Andreas
A1  - Weber, Stefan
A1  - Herzog, H.
A1  - Reinartz, R. [u.a.]
T1  - The design of an animal PET: flexible geometry for achieving optimal spatial resolution or high sensitivity
JF  - IEEE transactions on medical imaging. 16 (1997), H. 5
Y1  - 1997
SN  - 0278-0062
SP  - 684
EP  - 689
ER  - 
TY  - JOUR
A1  - Thiebes, Anja Lena
A1  - Klein, Sarah
A1  - Zingsheim, Jonas
A1  - Möller, Georg H.
A1  - Gürzing, Stefanie
A1  - Reddemann, Manuel A.
A1  - Behbahani, Mehdi
A1  - Cornelissen, Christian G.
T1  - Effervescent atomizer as novel cell spray technology to decrease the gas-to-liquid ratio
JF  - pharmaceutics
N2  - Cell spraying has become a feasible application method for cell therapy and tissue engineering approaches. Different devices have been used with varying success. Often, twin-fluid atomizers are used, which require a high gas velocity for optimal aerosolization characteristics. To decrease the amount and velocity of required air, a custom-made atomizer was designed based on the effervescent principle. Different designs were evaluated regarding spray characteristics and their influence on human adipose-derived mesenchymal stromal cells. The arithmetic mean diameters of the droplets were 15.4–33.5 µm with decreasing diameters for increasing gas-to-liquid ratios. The survival rate was >90% of the control for the lowest gas-to-liquid ratio. For higher ratios, cell survival decreased to approximately 50%. Further experiments were performed with the design, which had shown the highest survival rates. After seven days, no significant differences in metabolic activity were observed. The apoptosis rates were not influenced by aerosolization, while high gas-to-liquid ratios caused increased necrosis levels. Tri-lineage differentiation potential into adipocytes, chondrocytes, and osteoblasts was not negatively influenced by aerosolization. Thus, the effervescent aerosolization principle was proven suitable for cell applications requiring reduced amounts of supplied air. This is the first time an effervescent atomizer was used for cell processing.
KW  - tri-lineage differentiation
KW  - survival
KW  - twin-fluid atomizer
KW  - adipose-derived stromal cells (ASCs)
KW  - cell atomization
KW  - cell aerosolization
Y1  - 2022
U6  - https://doi.org/10.3390/pharmaceutics14112421
N1  - This article belongs to the Special Issue "Stromal, Stem, Signaling Cells: The Multiple Roles and Applications of Mesenchymal Cells"
VL  - 14
IS  - 11
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Naser, S.
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Crosssensitivity of a capacitive penicillin sensor combined with a diffusion barrier
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague)
SP  - 573
EP  - 576
CY  - The Hague, The Netherlands
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Naser, S.
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Cross-sensitivity of a capacitive penicillin sensor combined with a diffusion barrier
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. - Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors <13, 1999, 's-Gravenhage> ; Eurosensors <13, 1999, The Hague> ;  European Conference on Solid-State Transducers <13, 1999, The Hague>
SP  - 573
EP  - 576
CY  - The Hague, The Netherlands
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Schroth, P.
A1  - Töpler, A.
A1  - Schöning, Michael Josef
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Improving the detection limit of a capacitive sensor by means of a diffusion barrier
JF  - Eurosensors XII : proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13 - 16 September 1998 / ed. by N. M. White ; Vol. 1
Y1  - 1998
SN  - 0-7503-0595-9
N1  - Eurosensors ; (12, 1998, Southampton) ; UK Conference on Sensors and Their Applications ; (9, 1998, Southampton)
SP  - 507
EP  - 510
PB  - Inst. of Physics Publ.
CY  - Bristol [u.a.]
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Schöning, Michael Josef
A1  - Muchandani, A.
A1  - Wang, J.
A1  - Arzdorf, Michael
A1  - Mulchandani, P.
A1  - Chen, W.
T1  - Feldeffekt-Enzymsensor zur Detektion von Pestiziden
JF  - Sensoren für zukünftige Hochtechnologien und Neuentwicklungen für die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. Jörg Peter Baselt; Gerald Gerlach (Hg.)
Y1  - 2003
SN  - 3-935712-92-8
SP  - 125
EP  - 128
PB  - w.e.b.-Univ.-Verl.
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Thust, M.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Malkoc, Ü.
A1  - Dicker, C. I.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Enzyme immobilisation on planar and porous silicon substrates for biosensor applications
JF  - Journal of Molecular Catalysis B: Enzymatic. 7 (1999), H. 1-4
Y1  - 1999
SN  - 1381-1177
SP  - 77
EP  - 83
ER  - 
TY  - JOUR
A1  - Thust, Marion
A1  - Mulchandani, Ashok
A1  - Wang, Joseph
A1  - Arzdorf, Michael
A1  - Mulchandani, Priti
A1  - Chen, Wilfried
A1  - Schöning, Michael Josef
T1  - Feldeffekt-Enzymsensor zur Detektion von Pestiziden
JF  - Technisches Messen. 70 (2003), H. 12
Y1  - 2003
SN  - 0171-8096
SP  - 561
EP  - 564
ER  - 
TY  - JOUR
A1  - Thust, Marion
A1  - Schöning, Michael Josef
A1  - Frohnhoff, S.
A1  - Arens-Fischer, R.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Porous silicon as a substrate material for potentiometric biosensors
JF  - Measurement Science and Technology
Y1  - 1996
U6  - https://doi.org/10.1088/0957-0233/7/1/003
VL  - 7
IS  - 1
SP  - 26
EP  - 29
ER  - 
TY  - GEN
A1  - Topcu, Murat
A1  - Madabhushi, Gopal Santana Phani
A1  - Staat, Manfred
T1  - Datasets from FEM Simulations done with COMSOL Multiphysics and Code_Aster
N2  - Datasets from FEM Simulations done with COMSOL Multiphysics and Code_Aster for an elastic stress transfer between matrix and fibres having a variable radius.
KW  - Natural fibres
KW  - Polymer-matrix composites
KW  - Biocomposites
KW  - Stress concentrations
KW  - Finite element analysis (FEA)
Y1  - 2022
U6  - https://doi.org/10.6084/m9.figshare.19333295.v2
ER  -